James Konopka
@jkonopka.bsky.social
45 followers
55 following
14 posts
Professor of Microbiology and Immunology at Stony Brook University. My research laboratory studies pathogenic fungi to help
Identify Identify new therapies. As a hobby, I enjoy brewing beer. Fungi are fascinating!
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James Konopka
@jkonopka.bsky.social
· Jun 4
Proximity labeling identification of plasma membrane eisosome proteins in Candida albicans
Abstract. The ability of Candida albicans to resist stressful conditions in the host and grow invasively into tissues contributes to the virulence of this
academic.oup.com
James Konopka
@jkonopka.bsky.social
· Apr 29
The Cwr1 protein kinase localizes to the plasma membrane and mediates resistance to cell wall stress in Candida albicans | mSphere
The ability of Candida albicans to grow invasively in the host and resist stress is critical for it to be an effective
human pathogen. Identifying the genes that promote these processes is important f...
journals.asm.org
James Konopka
@jkonopka.bsky.social
· Feb 8
Pathogenic strategies of Pseudogymnoascus destructans during torpor and arousal of hibernating bats
Millions of hibernating bats across North America have died from white-nose syndrome (WNS), an emerging disease caused by a psychrophilic (cold-loving) fungus, Pseudogymnoascus destructans, that invad...
www.science.org
James Konopka
@jkonopka.bsky.social
· Feb 6
James Konopka
@jkonopka.bsky.social
· Jan 7
Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain - Nature
Cryo-electron microscopy, in vitro reconstitution and molecular dynamics simulations provide insight into the architecture of a plasma membrane microdomain in yeast, the organization and dynamics of t...
www.nature.com
James Konopka
@jkonopka.bsky.social
· Dec 30
Candida albicans resistance to hypochlorous acid | mBio
Hypochlorous acid (HOCl), commonly known as bleach, is generated during the respiratory burst by phagocytes and is a key weapon used to attack Candida albicans and other microbial pathogens. However, the effects of hypochlorous acid on C. albicans have ...
journals.asm.org
James Konopka
@jkonopka.bsky.social
· Dec 21
Sur7 mediates a novel pathway for PI4,5P2 regulation in C. albicans that promotes stress resistance and cell wall morphogenesis | Molecular Biology of the Cell
The human fungal pathogen Candida albicans can cause lethal systemic infections due to its ability to resist stress from the host and to undergo invasive hyphal growth. Previous studies showed that pl...
www.molbiolcell.org