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Josue Zambrano @josthescientist.bsky.social · Jul 27

Grateful for the opportunity to share my research about heart development and proteostasis at #BCVS25 #AHA.
I presented my research “RBX1 a novel, dosage sensitive regulator of perinatal heart development” in the Next best thing sessions where the top abstracts from grad students where selected.

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Reposted by Josue Zambrano

Nature Metabolism @natmetabolism.nature.com · Mar 22

RESEARCH | Y Wang, H Xie, Q Liu, CY Wang et al. (HUST, CN)

#Kdm2a demethylates #H3K36me2 to mediate fast-to-slow-twitch #myofiber transition and reshape #SkeletalMuscle metabolic flexibility under #metabolic stress conditions

Kdm2a inhibition in skeletal muscle improves metabolic flexibility in obesity - Nature Metabolism

Kdm2a demethylates H3K36me2 to mediate fast-to-slow-twitch myofiber transition and reshape skeletal muscle metabolic flexibility under metabolic stress conditions.

bit.ly

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Josue Zambrano @josthescientist.bsky.social · Feb 21

If you’re attending #APS25 and are interested in cardiac development stop by to my presentation and poster.
#Scisky #AcademicSky #BioSky #heart #research #PhD

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Josue Zambrano @josthescientist.bsky.social · Feb 21

So happy to share that I was selected as finalist for the Cardiovascular Section Outstanding Graduate Student Trainee Award of Physiological American Society #APS! 🤩
I will be presenting my research about ubiquitin E3 ligases in cardiac development 🫀 and compete against other two finalist. #APS25

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Reposted by Josue Zambrano

Nature Portfolio @natureportfolio.nature.com · Feb 8

There is evidence that technologies like search engines and GPS maps can alter our ability to learn and remember. Nature reports how scientists are now working out what AI might do to our memories. 🧪

Are the Internet and AI affecting our memory? What the science says

Search engines, GPS maps and other tech can alter our ability to learn and remember. Now scientists are working out what AI might do.

go.nature.com

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Reposted by Josue Zambrano

Communications Biology @commsbio.nature.com · Feb 7

Functional characterization of PfFBXO1, utilizing cell biology, genetics, and biochemistry, demonstrates essential roles for this protein in formation of the inner membrane complex in asexual merozoites and sexual-stage gametocytes.

www.nature.com/articles/s42...

PfFBXO1 is essential for inner membrane complex formation in Plasmodium falciparum during both asexual and transmission stages - Communications Biology

Functional characterization of PfFBXO1, utilizing cell biology, genetics, and biochemistry, demonstrates essential roles for this protein in formation of the inner membrane complex in asexual merozoit...

www.nature.com

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Reposted by Josue Zambrano

Molecular Cell @cp-molcell.bsky.social · Feb 7

Combinatorial mapping of E3 ubiquitin ligases to their target substrates

The substrate(s) of most E3 ubiquitin ligases remain unknown. Suiter et al. present COMET, a combinatorial framework for identifying proteolytic E3-substrate relationships at scale. Deep-learning-based structural prediction provides in silico validation…

dlvr.it

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Josue Zambrano @josthescientist.bsky.social · Jan 22

Newly moved from X! Looking forward to engage and interact with other #cardiovascular scientists on here 🦋.

#science #heart #cardiac #health #phd #scientist #research

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