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Reposted by Philipp Klein

Julia M. Rohrer @dingdingpeng.the100.ci · 4d

Happy to announce that I'll give a talk on how we can make rigorous causal inference more mainstream 📈

You can sign up for the Zoom link here: tinyurl.com/CIIG-JuliaRo...

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Philipp Klein @jpkhl.bsky.social · 7d

Digging somewhat deeper: Judea Pearl, the pioneer of modern causal inference: youtu.be/MNyI1Xkapxg?...

Philipp Klein @jpkhl.bsky.social · 9d

And about to inaugurate a new head of state this coming weekend, I just learned

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Philipp Klein @jpkhl.bsky.social · 14d

@mayer-l.bsky.social

Philipp Klein @jpkhl.bsky.social · 14d

www.researchgate.net/publication/...

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Philipp Klein @jpkhl.bsky.social · 14d

Congratulations, Lynn, on putting this together with such unwavering attention to detail! It has been a great pleasure working on this with you. And thank you wholeheartedly to Arnoud Arntz without whom this project would have been impossible!

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Philipp Klein @jpkhl.bsky.social · 14d

She highlights that the advantages of the BPD-CL include the fact that it measures all symptom domains considered necessary for the diagnosis of BPD in the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM).

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Philipp Klein @jpkhl.bsky.social · 14d

That is the result of a study just published by Lynn Mayer in the International Journal of Methods in Psychiatric Research.

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Philipp Klein @jpkhl.bsky.social · 14d

The Borderline Personality Disorder Checklist (BPD-CL) can be used for self-assessment in various languages because it is a reliable and valid measure of symptoms of BPD in its Dutch, English, German, Greek, Italian and Spanish version.

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Philipp Klein @jpkhl.bsky.social · 20d

A great thanks to @toshi-frkw.bsky.social and @dingdingpeng.the100.ci for nudging me in the direction of modern causal inference methods.

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Philipp Klein @jpkhl.bsky.social · 20d

Quite possibly one of the best presentations on how to conduct research. It is by Peter WG Tennant from the University of Leeds, UK and focusses on modern causal inference methods.

More on it here: youtube.com/playlist?lis...

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Reposted by Philipp Klein

Julia M. Rohrer @dingdingpeng.the100.ci · Sep 10

Getting ready to teach internal/external/construct validity, for the first time using the framing by Estlinger, @davebrady72.bsky.social and @eschwitz.bsky.social (www.degruyterbrill.com/document/doi...).

Super happy because this is much clearer than what I told student before!

Slide titled "Types of validity"

Violence in video games affects aggression in youths.

A affects B in C.

This statement is a generalization, of which any part could potentially be invalid.

Formalization of types of validity according to Estlinger et al., 2025

Slide titled: Overview validity

A influences B in C

Internal Validity: A influences B, rather than just being correlated with it.
Construct validity (of the manipulation/treatment/cause): It is indeed A that has the effect, and not something else.
Construct validity (of the effect, the outcome): It is indeed B that is being influenced
External validity: The effect indeed occurs in C.

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Philipp Klein @jpkhl.bsky.social · Sep 9

www.researchgate.net/publication/...

Philipp Klein @jpkhl.bsky.social · Sep 9

Congratulations, Katharina, on publishing this excellent study and thank you for letting me accompany you on this exciting scientific journey :-)

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Philipp Klein @jpkhl.bsky.social · Sep 9

That is likely due to the fact that, thankfully, QTc prolongation due to psychotropics is rare and a much larger trial would be needed to demonstrate the clinical effect of pharmacist support.

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Philipp Klein @jpkhl.bsky.social · Sep 9

They found that medical staff indeed enjoy the pharmacists support; and this support also enhances adherence to guidelines for monitoring QTc intervals. But it did not have an effect on clinical outcomes including changes in QTc time.

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Philipp Klein @jpkhl.bsky.social · Sep 9

But does this also lead to better outcomes? That is the question addressed by Katharina Wien from Stefan Borgwardt's research group at Lübeck University.

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Philipp Klein @jpkhl.bsky.social · Sep 9

Wouldn't it be wonderful if a pharmacist looked over your shoulder while prescribing psychotropics and made sure you are doing everything right to prevent your patient from prolonged QTc intervals and its consequences like life-threatening cardiac arrhythmias?

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Philipp Klein @jpkhl.bsky.social · Sep 9

Yes, the data are available from
the corresponding author. And thank you for your interest in this paper :-)

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Philipp Klein @jpkhl.bsky.social · Sep 9

www.researchgate.net/publication/...

Treatment expectations and depressive symptoms in an internet-based intervention for depression. A secondary analysis | Request PDF

Request PDF | On Aug 1, 2025, Gwendolyn Wälchli and others published Treatment expectations and depressive symptoms in an internet-based intervention for depression. A secondary analysis | Find, read ...

www.researchgate.net

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Philipp Klein @jpkhl.bsky.social · Sep 9

I am grateful for the opportunity to contribute to this work!

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Philipp Klein @jpkhl.bsky.social · Sep 9

They conclude that treatment expectations might be a therapeutic process that can be utilized to enhance treatment outcomes.

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Philipp Klein @jpkhl.bsky.social · Sep 9

This notion is supported by a recent study published by Thomas Berger's group from Bern, Switzerland. In a paper authored by Gwendolyn Wälchli they find that expectations developing during the course of therapy predict outcome but not expectations prior to the onset of therapy.

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Philipp Klein @jpkhl.bsky.social · Sep 9

It has often been suggested that psychotherapy works because patients expect it will work before they have even started treatment. But what if treatment expectations are an emergent phenomenon that develops in the course of psychotherapy and contributes to a successful outcome?

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Philipp Klein @jpkhl.bsky.social · Jul 23

If confirmed in randomized trials, enhancing the acquisition of skills taught in both BA and MCT could lead to greater treatment effectiveness.