John Weir
@jweir.bsky.social
860 followers 160 following 11 posts
Research Group Leader at the Max Planck in Tübingen. Protein biochemistry and meiosis.
Posts Media Videos Starter Packs
jweir.bsky.social
Congratulations Hassan, very well deserved!
jweir.bsky.social
Thanks a lot Ula, it was a really enjoyable visit!
Reposted by John Weir
mpi-bio-fml.bsky.social
Class 4b from Grundschule am Hechinger Eck visited our lab. 22 kids learned about DNA with @jweir.bsky.social, peered through microscopes to explore their cheek cells, insects & even carpet (!). Best part? DNA extraction from bananas! 🧬🍌 #biology #education #STEM #schoolvisit #DNA #MaxPlanck
jweir.bsky.social
Thank you to everyone involved in the project. Emma Kane provided outstanding leadership and supervision in the project, but we would like in particular to thank the @unituebingen.bsky.social students Lena Eckert and Lio Trefs for their amazing work!
jweir.bsky.social
We find that the proteins of the Ectocarpus axis have many features shared with other organisms, but in a unique combination. We speculate that the arrangement may allow brown algae to regulate recombination by diverse mechanisms of recruiting more or less ecHOP1 to chromosomes
jweir.bsky.social
Thanks to all the people involved in the project, in particular to the outstanding @unituebingen.bsky.social students Lena Eckert and Lio Trefs!
jweir.bsky.social
#AlphaFold2 found that ecRED1 had *six* candidate closure motifs. Careful biochemical analysis could only prove the veracity of one of these, but with the door open for the other motifs to be activated by post-translational modifications
jweir.bsky.social
We found that ecHOP1 has two splice variants. One, which contains two "closure motifs"- sequences that bind to other ecHOP1 proteins - and one isoform with none
jweir.bsky.social
Previous work from @eelcotromer.bsky.social and @bungoakiyoshi.bsky.social had identified potential candidates for two factors that assemble on meiotic chromosomes to form the "axis". We found that both of these proteins, ecHOP1 and ecRED1 are specifically expressed in meiotic tissue
jweir.bsky.social
This is a great opportunity to join two fantastic labs starting in an outstanding research environment. Apply!
mpi-bio-fml.bsky.social
Apply for a PhD in Biology! Exciting projects (part 1 of 5) from.
Beatrice Ramm & Can Aztekin (@canaztekin.bsky.social).
Contact your referees, prepare your documents & apply by 27 Jan. www.phd.tuebingen.mpg.de

#imprs #graduateprogram #maxplanck #phd #phdlife #phdpositiongermany
Reposted by John Weir
hunterlab.bsky.social
Registration now open for the 2025 EMBO workshop on Meiosis! June 22-26, 2025, Engelberg, Switzerland.
Deadline for abstract submissions and registration is Feb 15th, 2025. Lots of speaker slots will be selected from abstracts, so apply now! meetings.embo.org/event/25-mei...
Meiosis: Exploring diversity to discover the fundamentals
Meiosis is an essential cell division for sexual reproduction and fertility across eukaryotes. It involves a series of tightly regulated processes, including entry into meiosis, pairing of homologs, …
meetings.embo.org
Reposted by John Weir
biorxivpreprint.bsky.social
Kinetic and structure-based comparisons of silent and stimulatory flagellin interactions with TLR5 https://www.biorxiv.org/content/10.1101/2024.12.09.627598v1