Work by @jinyangliang.bsky.social , welcome on Bluesky Jinyang!

In conclusion, our new method Polarisation By Estimation of the Ancestral Recombination graph (PolarBEAR) offers a complementary or even alternative approach to outgroup-based polarization methods. (5/5)

Unfolded site frequency spectra (uSFS) can be inferred with great accuracy using a posterior averaging approach, even using positions where little signal for the ancestral allele is available. (4/5)

With currently available ARG inference methods, the polarization accuracy is lower than when using the true ARG. The best results are obtained by applying a UPGMA tree reconstruction on PSMC pairwise TMRCAs! (3/5)

When the ARG is known, polarization can be achieved with great accuracy at some positions, depending on the shape of the underlying marginal genealogy. (2/5)

New study from the Lab! Jinyang Liang assesses the possibility of inferring ancestral alleles (aka allele polarization) without outgroup sequence, using the ancestral recombination graph (ARG) alone. Here are some of our findings. (1/5)

The call for PhD positions at the Max Planck Institute for Evolutionary Biology is now open, including one in my group! www.evolbio.mpg.de/3017297/appl.... If you are interested in playing with ancestral recombination graphs, please reach out!

Mince, s'il se met en quête de parité, on va avoir Brigitte Bardot alors ?

(3/3) Check out details here pallareslab.github.io/bionoise2025... - We have only 40 spots, so register soon! @smbmathbiology.bsky.social

(2/3) Come to Tübingen to discuss this with us! We are hosting an SMBE Satellite Meeting on the 'Origin, Maintenance, and Evolution of Biological Noise' in June 2025. Co-organizers: Julien Dutheil, Nacho Bravo, and Dan Weinreich.

(1/3) Ever wonder if there is anything in common between people studying #plasticity, #variability, #robustness, #bethedging, #variance, error-prone #molecularmechanisms? Might we all be thinking about different manifestations of Biological Noise? @official-smbe.bsky.social @mpi-bio-fml.bsky.social

Geometriphylogenetics xkcd.com/3010