Karishma Bisht
@karishmabisht.bsky.social
LSRF Postdoc Fellow at Princeton University | te Velthuis Lab| Interested in RNA viruses #influenza #coinfection🧬🦠 🧫🔬🌡️| Previously #biofilms #pseudomonas #phages |She/Her|🇺🇸~🇮🇳
Reposted by Karishma Bisht
Now out in Science Advances: www.science.org/doi/10.1126/...
www.science.org
August 8, 2025 at 6:33 PM
Now out in Science Advances: www.science.org/doi/10.1126/...
Excited to share our latest preprint in which we integrate mathematical modeling with experimental approaches to investigate how ⬆️ temperature influences aberrant RNA synthesis and innate immunity in flu infection 🦠
Flu infection => temperature⬆️ => NP levels⬇️ => aberrant RNAs⬆️ => interferon⬆️. Elegant modeling and experimental work by @karishmabisht.bsky.social and @danielweilandt.bsky.social! Preprint: www.biorxiv.org/content/10.1...
www.biorxiv.org
May 20, 2025 at 3:58 PM
Excited to share our latest preprint in which we integrate mathematical modeling with experimental approaches to investigate how ⬆️ temperature influences aberrant RNA synthesis and innate immunity in flu infection 🦠
Reposted by Karishma Bisht
Reposted by Karishma Bisht
Our new paper is out: "Mapping the complete influenza A virus infection cycle through single vRNP imaging". Combining newly-developed single-molecule imaging approaches with in situ viral transcriptomics, we identify numerous non-canonical infection pathways.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mapping the complete influenza A virus infection cycle through single vRNP imaging
Cell-to-cell heterogeneity is a common feature of viral infection that can generate enormous complexity, complicating understanding of infection progression and interpretation of differences between v...
www.biorxiv.org
January 21, 2025 at 9:56 AM
Our new paper is out: "Mapping the complete influenza A virus infection cycle through single vRNP imaging". Combining newly-developed single-molecule imaging approaches with in situ viral transcriptomics, we identify numerous non-canonical infection pathways.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Karishma Bisht
Excited to share this new preprint showing that non-canonical influenza virus transcripts are produced in a sequence/RNA structure-dependent manner on aberrant RNAs: www.biorxiv.org/content/10.1...
A two-step mechanism for RIG-I activation by influenza virus mini viral RNAs
Influenza A virus (IAV) non-canonical replication products can be bound by various host pathogen sensors, including retinoic acid-inducible gene I (RIG-I). However, it is not clear why non-canonical I...
www.biorxiv.org
January 5, 2025 at 5:58 PM
Excited to share this new preprint showing that non-canonical influenza virus transcripts are produced in a sequence/RNA structure-dependent manner on aberrant RNAs: www.biorxiv.org/content/10.1...
Reposted by Karishma Bisht
Get ready for ASV 2025! The 2025 American Society for Virology meeting will be hosted by McGill University and held at the Palais des Congrès de Montréal, Montréal, Québec, Canada from July 14 - 17, 2025. Abstract submission, travel award apps, and registration are now open! asv.org/asv2025/regi...
Register 2025 | American Society for Virology
The 44th Annual Meeting of the American Society for Virology! Dates: July 14 – 17, 2025 (Monday – Thursday) Palais des congrès de Montréal Host: McGill University *TEACHER TRAVEL GRANTS: Applications…
asv.org
December 4, 2024 at 6:25 PM
Get ready for ASV 2025! The 2025 American Society for Virology meeting will be hosted by McGill University and held at the Palais des Congrès de Montréal, Montréal, Québec, Canada from July 14 - 17, 2025. Abstract submission, travel award apps, and registration are now open! asv.org/asv2025/regi...