A canonical problem in computer science is to find the shortest route to every point in a network. A new approach beats the classic algorithm taught in textbooks.

Scientists at EPFL have reimagined 3D printing by turning simple hydrogels into tough metals and ceramics. Their process allows multiple infusions of metal salts that form dense, high-strength structu...

The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.

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A research team led by Kyushu University has developed a new fabrication method for energy-efficient magnetic random-access memory (MRAM) using a new material called thulium iron garnet (TmIG) that ha...

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A groundbreaking Australian study reveals that fitter individuals actually use fewer heartbeats each day than their sedentary counterparts, dispelling the myth that exercise "uses up" heartbeats. Forg...

Three scientists, including one from the U.S., share the 2025 Nobel Prize in chemistry for developing “metal-organic frameworks,” versatile molecular cages that can trap contaminants, store energy and...

The Nobel Prize winner in Medicine is investigating genetic changes that could have given our species a competitive advantage, and the possibility of extracting the genome of the Flores hobbit

Where we explore the historical figures that count. An in-depth look at the history of mathematics, in chronological order, looking at the people, the theories, the ideas - with as fewer gaps as possi...

MIT engineers have developed a recipe for a printable aluminum alloy that can withstand high temperatures and is five times stronger than traditionally manufactured aluminum.

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Agency officials confirmed that layoffs are imminent this month, but declined to provide an exact number of affected employees.

Mathematician Terence Tao recently described how he used ChatGPT to help solve a math problem on MathOverflow.

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Endurance exercise promotes adaptive growth and improved function of myocytes, which is supported by increased mitochondrial activity. In skeletal muscle, these benefits are in part transcriptionally coordinated by peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α). The importance of PGC-1α to exercise-induced adaptations in the heart has been unclear. Here we show that deleting PGC-1α specifically in cardiomyocytes prevents the expected benefits from exercise training and instead leads to heart failure after just 6 weeks of training. Consistent with this, in humans, rare genetic variants in PPARGC1A, which encodes PGC-1α, are associated with increased risk of heart failure. In this model, we identify growth differentiation factor 15 (GDF15) as a key heart-secreted mediator that contributes to this dysfunction. Blocking cardiac Gdf15 expression improves cardiac performance and exercise capacity in these mice. Finally, in human heart tissue, lower cardiomyocyt

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Being named as a Nobel laureate is the ultimate prize for many scientists, but how do other science prizes compare?