Background Long Covid (LC) is associated with long-term health impacts that require ongoing support from healthcare services. We aimed to gain insights into patients' perceptions of their ongoing sy.....

Background and aim The COVID-19 pandemic has left a lasting imprint on immune function, particularly in the elderly—a population already vulnerable to immunosenescence. While acute and long-COVID immu...

Background Autonomic symptoms and orthostatic syndromes have been reported in Long COVID, but few studies have characterized findings using head up tilt table testing. Objective To characterize auto...

Current understanding of pediatric COVID-19-associated encephalopathy/encephalitis remains limited, particularly concerning the risk factors for morta…

Using data from the United States Centers for Disease Control and Prevention (CDC) disease surveillance systems, we sought to quantify the indirect effects of the COVID-19 pandemic, and the possibilit...

Long COVID, a multisystemic syndrome following SARS-CoV-2 infection characterized by persistent immune dysregulation, systemic inflammation, and neuroimmune dysfunction, is a significant area of inves...

Scientific Reports - Long-term retinal oximetry and OCT angiography in patients recovered from COVID-19

The COVID-19 pandemic led to substantial health services disruption in England. Health-care policy makers need reliable national-level information on …

ObjectivesTo describe clinical and cardiologic findings in patients with multisystem inflammatory

COVID vaccines enhance the antitumour response of immunotherapies and result in increased patient survival.

This cohort study examines the presence, severity, and patterns of olfactory dysfunction in US adults with and without prior SARS-CoV-2 infection.

COVID-19 caused by SARS-CoV-2 is often compared to other pandemics for its societal and global health impact, with some commentators drawing parallels to HIV/AIDS due to the immune dysfunction caused ...

Researchers say that the number of infections for this time of year is unusual.

Whether paternal pre-conceptual SARS-CoV-2 infection impacts sperm RNA content, or effects offspring phenotypes, has not been previously investigated. Here authors report changes in sperm noncoding RNAs in SARS-CoV-2 infected sires and increased anxiety-like behaviors in offspring.

Author summary Why was this study done? It is known that people may suffer medical complications long after COVID-19, which are called post-acute sequelae (PAS). Similar sequelae are also known to h...

Objective This study aims to investigate the impact of SARS-CoV-2 infection on HPV-related cancer and carcinoma in situ. Method We utilized data from TriNetX, a database encompassing 106 healthcare organizations spanning 15 countries and comprising information from over 124 million participants. Propensity score matching was utilized to compare two cohorts: SARS-CoV-2 infection and non- SARS-CoV-2 infection groups. The cohorts consisted of females aged 18–90 with no previous history of HPV-related cancers before SARS-CoV-2 infection in 2020 and no HPV vaccine before 2020. We utilized Cox proportional hazard regression analysis to estimate hazard ratios (HRs) and their corresponding 95% confidence intervals (CIs). Subgroup analyses were performed based on age and race to validate the findings. Results The study included a total of 4,872,295 patients, with 1,281,997 in the SARS-CoV-2 infection group and 3,590,298 in the non-infection group. After propensity score matching, both groups comprised 1,281,997 patients each. Over a 3-year follow-up period, individuals with SARS-CoV-2 infection had significantly higher risks of developing HPV-related cancers compared to those without infection: a 67% increase in cervical cancer, 131% in vaginal cancer, 98% in vulvar cancer, 92% in anal cancer, and 78% in oropharyngeal cancer. Similar trends were observed for carcinoma in situ, with increased risks of 34% for cervical, 61% for vaginal, 74% for vulvar, 96% for anal, and 78% for oropharyngeal carcinoma in situ. Subgroup analyses stratified by age and race demonstrated consistent results. Conclusion SARS-CoV-2 infection is associated with elevated risks of HPV-related carcinoma in situ and cancer, irrespective of age or race. The findings underscore the importance of understanding the interplay between viral infections and cancer development, particularly in the context of the COVID-19 pandemic.

Scientific Reports - Persistent neuromuscular disorders associated with changes in tibialis anterior and gastrocnemius lateralis muscle architecture in long-covid: an observational longitudinal study

npj Dementia - COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years

Eye - Ophthalmic complications associated with COVID-19: a large US national database analysis