Alex Costa
@labcosta.bsky.social
Editorial Board @PlantCellEnvir, Board of Advisors @New Phytol, and @Facultyopinions
#Calcium #signaling #Arabidopsis #organelles #PCS #imaging
#Calcium #signaling #Arabidopsis #organelles #PCS #imaging
We thank Jon K. Pittman for his thoughtful and inspiring commentary
nph.onlinelibrary.wiley.com/doi/10.1111/...
published in @newphyt.bsky.social
on our recent work (Grenzi et al. 2025)
nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com/doi/10.1111/...
published in @newphyt.bsky.social
on our recent work (Grenzi et al. 2025)
nph.onlinelibrary.wiley.com/doi/10.1111/...
February 1, 2026 at 2:49 PM
We thank Jon K. Pittman for his thoughtful and inspiring commentary
nph.onlinelibrary.wiley.com/doi/10.1111/...
published in @newphyt.bsky.social
on our recent work (Grenzi et al. 2025)
nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com/doi/10.1111/...
published in @newphyt.bsky.social
on our recent work (Grenzi et al. 2025)
nph.onlinelibrary.wiley.com/doi/10.1111/...
🔥 Spodoptera littoralis feeding doesn’t just spike cytosolic Ca²⁺ — it also unleashes a surge of apoplastic glutamate in Nicotiana benthamiana
@ScienceAdvances
science.org/doi/10.1126/...
@ScienceAdvances
science.org/doi/10.1126/...
January 30, 2026 at 7:43 AM
🔥 Spodoptera littoralis feeding doesn’t just spike cytosolic Ca²⁺ — it also unleashes a surge of apoplastic glutamate in Nicotiana benthamiana
@ScienceAdvances
science.org/doi/10.1126/...
@ScienceAdvances
science.org/doi/10.1126/...
Registration is now OPEN for the EMBO Workshop on Plant Calcium Signaling 2026!
Dive into cutting-edge research on Ca²⁺ signaling in plants 🌿
📍 Primosten, Croatia | 🗓️ 20–24 September 2026
meetings.embo.org/event/26-cal...
Dive into cutting-edge research on Ca²⁺ signaling in plants 🌿
📍 Primosten, Croatia | 🗓️ 20–24 September 2026
meetings.embo.org/event/26-cal...
January 27, 2026 at 9:53 AM
Registration is now OPEN for the EMBO Workshop on Plant Calcium Signaling 2026!
Dive into cutting-edge research on Ca²⁺ signaling in plants 🌿
📍 Primosten, Croatia | 🗓️ 20–24 September 2026
meetings.embo.org/event/26-cal...
Dive into cutting-edge research on Ca²⁺ signaling in plants 🌿
📍 Primosten, Croatia | 🗓️ 20–24 September 2026
meetings.embo.org/event/26-cal...
The MAPPI setup we @AndreaBassi78 @labcosta.bsky.social
published in @ScienceAdvances shows its versatility, enabling us to design amazing experiments that we never thought could be possible...
science.org/doi/10.1126/...
So, now guess what this video is showing❔❔
published in @ScienceAdvances shows its versatility, enabling us to design amazing experiments that we never thought could be possible...
science.org/doi/10.1126/...
So, now guess what this video is showing❔❔
January 26, 2026 at 3:11 PM
The MAPPI setup we @AndreaBassi78 @labcosta.bsky.social
published in @ScienceAdvances shows its versatility, enabling us to design amazing experiments that we never thought could be possible...
science.org/doi/10.1126/...
So, now guess what this video is showing❔❔
published in @ScienceAdvances shows its versatility, enabling us to design amazing experiments that we never thought could be possible...
science.org/doi/10.1126/...
So, now guess what this video is showing❔❔
@labcosta.bsky.social Out now in ScienceAdvances
our new work with @AndreaBassi78
MAcro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging | Science Advances science.org/doi/10.1126/...
our new work with @AndreaBassi78
MAcro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging | Science Advances science.org/doi/10.1126/...
January 23, 2026 at 8:13 PM
@labcosta.bsky.social Out now in ScienceAdvances
our new work with @AndreaBassi78
MAcro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging | Science Advances science.org/doi/10.1126/...
our new work with @AndreaBassi78
MAcro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging | Science Advances science.org/doi/10.1126/...
🚀 New Review out by @elenist.bsky.social @labcosta.bsky.social
Bioelectronics for basic plant science and precision agriculture 🌱⚡️
A deep dive into how bioelectronic tools are transforming plant research & farming...
Published in Nature Reviews Electrical Engineering: doi.org/10.1038/s442...
Bioelectronics for basic plant science and precision agriculture 🌱⚡️
A deep dive into how bioelectronic tools are transforming plant research & farming...
Published in Nature Reviews Electrical Engineering: doi.org/10.1038/s442...
January 15, 2026 at 6:32 AM
🚀 New Review out by @elenist.bsky.social @labcosta.bsky.social
Bioelectronics for basic plant science and precision agriculture 🌱⚡️
A deep dive into how bioelectronic tools are transforming plant research & farming...
Published in Nature Reviews Electrical Engineering: doi.org/10.1038/s442...
Bioelectronics for basic plant science and precision agriculture 🌱⚡️
A deep dive into how bioelectronic tools are transforming plant research & farming...
Published in Nature Reviews Electrical Engineering: doi.org/10.1038/s442...
Plant Physiology @plantphys.bsky.social by Denise Scuffi @charliemdq.bsky.social is the Article of the Week
doi.org/10.1093/plph...
doi.org/10.1093/plph...
Hydrogen sulfide modulates flagellin-induced stomatal immunity
Hydrogen sulfide and L-CYSTEINE DESULFHYDRASE1 actively participate in flagellin-induced stomatal closure, modulating apoplastic and cytosolic reactive oxy
doi.org
January 10, 2026 at 10:19 AM
Plant Physiology @plantphys.bsky.social by Denise Scuffi @charliemdq.bsky.social is the Article of the Week
doi.org/10.1093/plph...
doi.org/10.1093/plph...
Huge thanks to @Nikon for an unforgettable Christmas present 🎁 Feeling truly privileged to receive such a unique microscope 🔬
January 5, 2026 at 1:28 PM
Huge thanks to @Nikon for an unforgettable Christmas present 🎁 Feeling truly privileged to receive such a unique microscope 🔬
Small molecule, big impact: H2S contributes to pathogen-induced stomatal closure url: academic.oup.com/plphys/artic...
Really nice News & Views on the new paper from @charliemdq.bsky.social’s lab 👏
academic.oup.com/plphys/artic...
Really nice News & Views on the new paper from @charliemdq.bsky.social’s lab 👏
academic.oup.com/plphys/artic...
Small molecule, big impact: H2S contributes to pathogen-induced stomatal closure
Plants are sessile organisms and must integrate information from a range of external stimuli to respond appropriately to their environment. Stomata form a
academic.oup.com
December 27, 2025 at 6:55 AM
Small molecule, big impact: H2S contributes to pathogen-induced stomatal closure url: academic.oup.com/plphys/artic...
Really nice News & Views on the new paper from @charliemdq.bsky.social’s lab 👏
academic.oup.com/plphys/artic...
Really nice News & Views on the new paper from @charliemdq.bsky.social’s lab 👏
academic.oup.com/plphys/artic...
Reposted by Alex Costa
Just for Xmas! Nice collaboration with @schwarzlanderlab.bsky.social and @labcosta.bsky.social labs.
Hydrogen sulfide modulates flagellin-induced stomatal immunity url: academic.oup.com/plphys/artic...
Hydrogen sulfide modulates flagellin-induced stomatal immunity url: academic.oup.com/plphys/artic...
Hydrogen sulfide modulates flagellin-induced stomatal immunity
Hydrogen sulfide and L-CYSTEINE DESULFHYDRASE1 actively participate in flagellin-induced stomatal closure, modulating apoplastic and cytosolic reactive oxy
academic.oup.com
December 24, 2025 at 11:08 AM
Just for Xmas! Nice collaboration with @schwarzlanderlab.bsky.social and @labcosta.bsky.social labs.
Hydrogen sulfide modulates flagellin-induced stomatal immunity url: academic.oup.com/plphys/artic...
Hydrogen sulfide modulates flagellin-induced stomatal immunity url: academic.oup.com/plphys/artic...
Great collaboration with @Charlie Garcia-Mata lab!
🧪 New Plant Physiology paper: Hydrogen sulfide modulates flagellin-induced stomatal immunity, revealing a key role for H₂S in guard cell immune responses 🌱
academic.oup.com/plphys/artic...
🧪 New Plant Physiology paper: Hydrogen sulfide modulates flagellin-induced stomatal immunity, revealing a key role for H₂S in guard cell immune responses 🌱
academic.oup.com/plphys/artic...
Hydrogen sulfide modulates flagellin-induced stomatal immunity
Hydrogen sulfide and L-CYSTEINE DESULFHYDRASE1 actively participate in flagellin-induced stomatal closure, modulating apoplastic and cytosolic reactive oxy
academic.oup.com
December 23, 2025 at 6:18 PM
Great collaboration with @Charlie Garcia-Mata lab!
🧪 New Plant Physiology paper: Hydrogen sulfide modulates flagellin-induced stomatal immunity, revealing a key role for H₂S in guard cell immune responses 🌱
academic.oup.com/plphys/artic...
🧪 New Plant Physiology paper: Hydrogen sulfide modulates flagellin-induced stomatal immunity, revealing a key role for H₂S in guard cell immune responses 🌱
academic.oup.com/plphys/artic...
Reposted by Alex Costa
Subfamily I ethylene receptors are functionally conserved in calcium permeability across the green lineage #research #MolecularPlant cell.com/molecular-pl...
December 23, 2025 at 6:33 AM
Subfamily I ethylene receptors are functionally conserved in calcium permeability across the green lineage #research #MolecularPlant cell.com/molecular-pl...
Merry Christmas and Happy Holidays from @labcosta.bsky.social! 🎄✨ Thanks to all our collaborators, colleagues, and friends for a great year together.
December 19, 2025 at 5:35 PM
Merry Christmas and Happy Holidays from @labcosta.bsky.social! 🎄✨ Thanks to all our collaborators, colleagues, and friends for a great year together.
Reposted by Alex Costa
Investigating the origin of spontaneous cytosolic calcium oscillations in stomatal guard cells: a dialogue between apoplastic and endoplasmic reticulum stores
Grenzi et al. @labcosta.bsky.social
nph.onlinelibrary.wiley.com/share/KRMCPP...
Grenzi et al. @labcosta.bsky.social
nph.onlinelibrary.wiley.com/share/KRMCPP...
December 15, 2025 at 11:17 PM
Investigating the origin of spontaneous cytosolic calcium oscillations in stomatal guard cells: a dialogue between apoplastic and endoplasmic reticulum stores
Grenzi et al. @labcosta.bsky.social
nph.onlinelibrary.wiley.com/share/KRMCPP...
Grenzi et al. @labcosta.bsky.social
nph.onlinelibrary.wiley.com/share/KRMCPP...
...we can infer that, in the presence of CPA, the ER behaves like anengine without fuel, incapable of sustaining the mechanism required to maintain the [Ca²⁺]cyt oscillations... doi.org/10.1111/nph....
December 16, 2025 at 6:50 AM
...we can infer that, in the presence of CPA, the ER behaves like anengine without fuel, incapable of sustaining the mechanism required to maintain the [Ca²⁺]cyt oscillations... doi.org/10.1111/nph....
Blue light decreases ER Ca²⁺ in stomatal guard cells, with refilling in the dark. Our new @newphyt.bsky.social study shows how ER Ca²⁺ shapes cytosolic Ca²⁺ dynamics
doi.org/10.1111/nph....
doi.org/10.1111/nph....
December 13, 2025 at 7:27 AM
Blue light decreases ER Ca²⁺ in stomatal guard cells, with refilling in the dark. Our new @newphyt.bsky.social study shows how ER Ca²⁺ shapes cytosolic Ca²⁺ dynamics
doi.org/10.1111/nph....
doi.org/10.1111/nph....
Two acceptances back-to-back on plant Ca²⁺ signaling!
🌱 The ER role in guard cell Ca²⁺ signaling
@newphyt.bsky.social
🔬 A new way to perform Ca²⁺ imaging in adult plants grown under physiological conditions
Science Advances @science.org
Stay tuned — details coming soon!
🌱 The ER role in guard cell Ca²⁺ signaling
@newphyt.bsky.social
🔬 A new way to perform Ca²⁺ imaging in adult plants grown under physiological conditions
Science Advances @science.org
Stay tuned — details coming soon!
December 12, 2025 at 8:45 AM
Two acceptances back-to-back on plant Ca²⁺ signaling!
🌱 The ER role in guard cell Ca²⁺ signaling
@newphyt.bsky.social
🔬 A new way to perform Ca²⁺ imaging in adult plants grown under physiological conditions
Science Advances @science.org
Stay tuned — details coming soon!
🌱 The ER role in guard cell Ca²⁺ signaling
@newphyt.bsky.social
🔬 A new way to perform Ca²⁺ imaging in adult plants grown under physiological conditions
Science Advances @science.org
Stay tuned — details coming soon!
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance | Science www.science.org/doi/10.1126/...
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance
Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...
www.science.org
October 11, 2025 at 8:59 AM
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance | Science www.science.org/doi/10.1126/...
Farewell party for Matteo! After 8 successful years in my lab, he is now ready to begin a new adventure in Sierla’s lab at
@helsinki.fi. Wishing him the best of luck!
@helsinki.fi. Wishing him the best of luck!
September 27, 2025 at 4:38 AM
Farewell party for Matteo! After 8 successful years in my lab, he is now ready to begin a new adventure in Sierla’s lab at
@helsinki.fi. Wishing him the best of luck!
@helsinki.fi. Wishing him the best of luck!
🍕 Pizza day for @lab_costa with our new guests from Spain — Jorge Morello (Miguel Botella lab, Malaga) and Pavel Brito-Gutiérrez (Maite Sanmartín lab, Valencia). Great way to kick things off!
September 12, 2025 at 4:27 PM
🍕 Pizza day for @lab_costa with our new guests from Spain — Jorge Morello (Miguel Botella lab, Malaga) and Pavel Brito-Gutiérrez (Maite Sanmartín lab, Valencia). Great way to kick things off!
Differential regulation of calcium-activated plant kinases in Arabidopsis thaliana 🌱
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
September 11, 2025 at 4:47 PM
Differential regulation of calcium-activated plant kinases in Arabidopsis thaliana 🌱
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
A fascinating insight into how plants decode Ca²⁺ signals through CPKs — revealing specificity in calcium signaling.
🔗 onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Alex Costa
Why would anyone want to be a scientist?
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
September 7, 2025 at 12:06 PM
Why would anyone want to be a scientist?
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."
journals.biologists.com/jcs/article/...
Thrilled to share that Stefano Buratti has been awarded the Fratelli Confalonieri Postdoctoral Fellowship! He'll be joining my lab @LaStatale to develop innovative tools for exploring plant–environment interactions. Congratulations, Stefano!
June 10, 2025 at 6:53 PM
Thrilled to share that Stefano Buratti has been awarded the Fratelli Confalonieri Postdoctoral Fellowship! He'll be joining my lab @LaStatale to develop innovative tools for exploring plant–environment interactions. Congratulations, Stefano!
Reposted by Alex Costa
What started as a 'funky' observation back in 2017 while visiting the lab of @labcosta.bsky.social, and after skilfull execution of Dominic Kuang, Shanna Romand, and many more, now found a home in Current Biology. www.sciencedirect.com/science/arti...
The burning glass effect of water droplets triggers a high light-induced calcium response in the chloroplast stroma
Plants rely on water and light for photosynthesis, but water droplets on leaves can focus light into high-intensity spots, risking photodamage. Excess…
www.sciencedirect.com
May 20, 2025 at 3:21 PM
What started as a 'funky' observation back in 2017 while visiting the lab of @labcosta.bsky.social, and after skilfull execution of Dominic Kuang, Shanna Romand, and many more, now found a home in Current Biology. www.sciencedirect.com/science/arti...