levkats.bsky.social
@levkats.bsky.social
Heme biosynthesis is a really fascinating pathway. We think targeting the enzymes that make heme is a really promising strategy for AML. Check out our paper online today in @cellpress.bsky.social @petermaccc.bsky.social

www.cell.com/cell/fulltex...
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
Reduced levels of the essential metabolite heme are a common feature of acute myeloid leukemia, and consequently, leukemic cells are highly sensitive to inhibition of de novo heme synthesis. Blockade ...
www.cell.com
November 20, 2025 at 6:07 AM