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Lightcast
@lightcastbio.bsky.social
At Lightcast we are enabling scientists to gain a deeper understanding of human health and disease at the cellular level.
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At Lightcast, we're developing a flexible platform to enables direct, precise interrogation of #SingleCell heterogeneity, interactions, and functional behaviours at scale. We aim to provide the freedom to accelerate discovery and apply novel biological insights.
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#ScienceSky 🧪
Seamlessly customise your single-cell workflow with Lightcast
YouTube video by Lightcast
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We're on-site at #PEGSEurope today ready to answer your questions about function-focused #SingleCellAnalysis. Join Paul Wylie's presentation TODAY at 12.15 pm GMT (Auditorium 3-4) and then meet the rest of the team at Booth #325 to see our Envisia technology in action!
November 11, 2025 at 10:47 AM
We're looking forward to bringing our Envisia benchtop #SingleCellAnalysis platform to Lisbon for #PEGSEurope next week! Drop by poster session A078 on Nov. 11-12, or join a software demo at Booth #325.

#microfluidics #ScienceSky 🧪 #AcademicSky
November 4, 2025 at 11:59 AM
Just a couple of weeks until we're back at #PEGSEurope in Lisbon! Find the Lightcast team & our Envisia instrument at Stand #325, or join our luncheon presentation "Envisia: Advancing Antibody Discovery with Single-Cell, Function-Focused Profiling" on Nov. 11 at 12:15 PM.

#SingleCell #Microfluidics
October 28, 2025 at 9:35 AM
Day 2 of #ELRIGDD25 is just getting started! The Lightcast team is on-booth at #F08, ready to show you our Envisia benchtop platform and answer your questions about function-focused #SingleCell analysis!
October 22, 2025 at 9:15 AM
We're looking forward to connecting at ELRIG #DrugDiscovery2025 next week! In this clip from last year's conference, Lightcast Dir. of Portfolio Management shares what he values most about being part of the ELRIG community.

Find Paul and the Lightcast team in Booth F08!
October 16, 2025 at 11:10 AM
“Phenotype tells you what a cell is — but 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻 tells you if it has 𝗿𝗲𝗮𝗹 𝘁𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹.” 💡

In this video, Lightcast Assoc. Dir. of Commercial Development Carrie Maynard explains why functional assays are so important for driving innovation in #DrugDiscovery.

#ScienceSky #SingleCell
September 23, 2025 at 11:30 AM
Antibody-based immunotherapies can target disease with high precision — but #AntibodyDiscovery workflows are slow & costly.

Using streamlined functional analysis earlier in the discovery process can help deliver promising therapies quicker, writes our own Jonathan Didier.

go.lightcast.bio/47R6ZoF
Why antibody discovery needs to focus on function
Early functional testing could transform the future of antibody-based therapies — here’s how.
www.drugdiscoverynews.com
September 22, 2025 at 3:23 PM
#AntibodyDiscovery is at a turning point: traditional methods focused on binding rather than function are no longer sufficient.

By leveraging droplet #microfluidics our Envisia platform enables deeper analysis of cellular functions.

Learn more at our presentation @ the #FestivalofBiologics!
September 16, 2025 at 1:01 PM
Our Envisia benchtop platform supports a wide range of #SingleCell functional assays — all designed to deepen understanding of cellular heterogeneity & cell-specific behaviours.

Find out how you can quickly & more confidently identify promising candidates: go.lightcast.bio/42a4Dxc

#Microfluidics
September 2, 2025 at 12:31 PM
There's a hint of autumn in the air 🍂 , which can only mean one thing: Our team will soon be on the road again!

Meet us at an upcoming event to find out more about unlocking deeper #SingleCell insights w/our Envisia benchtop platform.

More info on our website: go.lightcast.bio/4n2itKm
August 26, 2025 at 12:27 PM
Capturing functional readouts like 𝗯𝗶𝗼𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗲 𝘀𝗲𝗰𝗿𝗲𝘁𝗶𝗼𝗻, 𝗮𝗻𝘁𝗶𝗯𝗼𝗱𝘆 𝗯𝗹𝗼𝗰𝗸𝗶𝗻𝗴 & 𝘁𝗮𝗿𝗴𝗲𝘁 𝗰𝗲𝗹𝗹 𝗸𝗶𝗹𝗹𝗶𝗻𝗴 at the #SingleCell level helps researchers gain a deeper understanding of cell behaviour & therapeutic potential, improving #DrugDiscovery timelines.

Learn more: go.lightcast.bio/45WSPAP

#ScienceSky 🧪
August 19, 2025 at 3:02 PM
Our Envisia platform takes a function-focused approach to #AntibodyDiscovery, streamlining the discovery workflow with:

1️⃣ Real-time functional insights
2️⃣ Multi-assay screening
3️⃣ Faster hit identification & single-cell recovery
4️⃣ oEWOD technology to eliminate crosstalk

go.lightcast.bio/47w2EH3
Four ways Envisia is changing the game in antibody discovery
By integrating single-cell analysis, multi-functional assays, and robust cell recovery into one seamless system, Lightcast empowers researchers to shift from a binding-first approach to a function-focused paradigm. Workflows on the Envisia platform has the potential to enhance lead quality, reduce attrition rates, and accelerate the discovery of antibodies with real therapeutic potential.
go.lightcast.bio
August 14, 2025 at 12:06 PM
Whether we’re developing new workflows, implementing updates to our smart cartridge system, or testing new software features, one thing is clear: success comes from sharing & building on ideas within and across teams.

Learn more about what drives our team: lnkd.in/e7gbeBeN

#ScienceJobs #ScienceSky
July 18, 2025 at 8:22 AM
Designed with scientists in mind, our software combines an intuitive user experience with powerful algorithms, enabling analysis of even the most complex functional behaviours.

Get results faster, with less time spent learning a new software platform. (1/3)

#ScienceSky #AcademicSky #SingleCell
July 16, 2025 at 10:40 AM
Signal crosstalk between neighbouring cells or reactions can lead to noisy, unreliable data and compromised decision-making. The Envisia platform uses enclosed droplet microenvironments to isolate each cell and its functional assay. (1/3)

#SingleCell #ScienceSky #Microfluidics
July 9, 2025 at 12:43 PM
We're still seeking two commercial development associates to support the commercial expansion of our Envisia benchtop platform in the U.S. and European markets.

Learn more and apply: go.lightcast.bio/4lHCKEp

#ScienceJobs #ScienceSky 🧪 #Hiring
July 3, 2025 at 8:16 AM
We're seeking a Commercial Development Associate to help us put our groundbreaking function-focused single-cell analysis technology into the hands of researchers in North America.

📍Boston, US

Learn more & apply: go.lightcast.bio/3HTdg8q

#ScienceSky #Hiring #ScienceJobs #ResearchJobs #AcademicSky
June 26, 2025 at 2:49 PM
(1/3) Why does our Envisia platform use droplets? Picolitre-sized droplets are fundamental to isolating individual cells and enabling complex, multi-step assays — without losing biological context or introducing noise from secreted biomolecules.

Learn more: go.lightcast.bio/3FZ0zby

#microfluidics
June 19, 2025 at 1:16 PM
Still relying on binding-focused approaches in #AntibodyDiscovery? You could be missing your best functional candidates. Envisia, our next-generation, single-cell platform, was designed to prioritise cellular & antibody functionality from the very start.

go.lightcast.bio/4k0KyQa

#ScienceSky 🧪
Four ways Envisia is changing the game in antibody discovery
By integrating single-cell analysis, multi-functional assays, and robust cell recovery into one seamless system, Lightcast empowers researchers to shift from a binding-first approach to a function-foc...
www.lightcast.bio
June 19, 2025 at 10:28 AM
How can our benchtop Envisia platform accelerate #AntibodyDiscovery by bringing key cellular functions — including cytokine secretion, internalisation, and serial killing — into focus? Watch the video to learn more.

#ScienceSky 🧪 #AcademicSky #Microfluidics

www.youtube.com/watch?v=YctY...
Lightcast: The functional readouts guiding antibody discovery
YouTube video by Lightcast
www.youtube.com
June 11, 2025 at 12:14 PM
Reposted by Lightcast
From load to dispense in under 6 hours?

Paul Wylie, Lightcast Dir. of Portfolio Management, walks through some of the Envisia #microfluidic platform's key features (like speed!), live from our booth at #PEGS2025.

Learn more about Envisia: go.lightcast.bio/42ZdDGx

www.youtube.com/watch?v=GjEW...
Lightcast at PEGS 2025
YouTube video by Lightcast
www.youtube.com
May 15, 2025 at 1:39 PM
Reposted by Lightcast
Last week at #PEGSummit, we were delighted to reveal our Envisia platform to a global audience — and even more thrilled by the interest and engagement we received. Watch the video to see Envisia in action & hear about Lightcast's plans for the future of #SingleCell.

www.youtube.com/watch?v=pePx...
Showcasing the future of single-cell analysis at PEGS 2025
YouTube video by Lightcast
www.youtube.com
May 20, 2025 at 4:01 PM
Reposted by Lightcast
Centrally located among biotechs and universities in Kendall Square, our Boston Innovation Center (BIC) manages feasibility studies for our North American customers.

📹 Meet BIC Head Megan Gottlieb and Product Applications Scientist Jassmine Ibea.

#ScienceSky 🧪

www.youtube.com/watch?v=57JW...
Meet the team at Lightcast's Boston Innovation Center
YouTube video by Lightcast
www.youtube.com
May 27, 2025 at 2:32 PM
Reposted by Lightcast
More about our Envisia benchtop platform: www.lightcast.bio/technology/e...

#microfluidics #ScienceSky
May 29, 2025 at 1:05 PM
Reposted by Lightcast
#AntibodyDiscovery is often a slow process — especially when multiple functional assays are spread across different instruments in the lab.

👉 Discover how a unified, function-focused platform like Envisia accelerates the discovery process: go.lightcast.bio/43HuFrR

#ScienceSky 🧪 #AcademicSky
May 29, 2025 at 1:05 PM