Lightnews — Scholar-powered news

Giordano Lippi @lippilab.bsky.social · 2d

Come to the Symposium

Ardem Patapoutian @ardemp.bskyverified.social · 2d

Attending #SfN2025 in San Diego☀️? Don’t miss the Dorris Neuroscience Center Symposium at @scripps.edu, happening right before the meeting. A great lineup of speakers to kick off your SfN week. Plan your trip accordingly and register for free here:
www.eventbrite.com/e/dorris-neu...

Please amplify!

2

Giordano Lippi @lippilab.bsky.social · 28d

Congrats!

Reposted by Giordano Lippi

Scripps Research @scripps.edu · Sep 8

In our first pitch session, Ryan Shenvi, PhD, @lippilab.bsky.social, PhD, and Li Ye, PhD, will each share their approach to understanding the brain—from neuroactive compound synthesis, to microRNAs in circuit development, to brain energetics—and will take questions after each of their pitches.

1 1 3

Giordano Lippi @lippilab.bsky.social · Aug 23

Congrats!

1 2

Giordano Lippi @lippilab.bsky.social · Aug 12

Congrats!

1

Giordano Lippi @lippilab.bsky.social · Jul 23

Yeah Marko!

1

Giordano Lippi @lippilab.bsky.social · Jun 13

Congrats

1 1

Giordano Lippi @lippilab.bsky.social · May 28

🎉

1

Giordano Lippi @lippilab.bsky.social · May 21

First author @norjin.bsky.social has a different version of the birth of this project. A classic case of convergent evolution.

1 1

Giordano Lippi @lippilab.bsky.social · May 21

How fitting that the Preview of our Neuron paper was written by the one and only Roy Sillitoe. I saw him giving a talk at the 2018 Neural Development GRC, and his incredible data, storytelling, and enthusiasm convinced me to use Purkinje Cells as a model system.
www.cell.com/neuron/fullt...

Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor

Zolboot et al.1 developed tools to manipulate and map microRNA function in cerebellar Purkinje cells with temporal precision, revealing key roles in dendritic development and circuit connectivity. The...

www.cell.com

1 1 6

Giordano Lippi @lippilab.bsky.social · May 18

Wow! Great stuff Debby congrats!

1 3

Giordano Lippi @lippilab.bsky.social · Apr 26

😂

1

Giordano Lippi @lippilab.bsky.social · Apr 24

Congrats buddy! 🎉🎉

1

Giordano Lippi @lippilab.bsky.social · Apr 22

Congrats!

2

Giordano Lippi @lippilab.bsky.social · Apr 20

Congrats Alex!

4

Giordano Lippi @lippilab.bsky.social · Apr 20

Congrats Chen!

1

Giordano Lippi @lippilab.bsky.social · Apr 17

Congrats Emilia!

1

Reposted by Giordano Lippi

Joris de Wit @synapse-lab.bsky.social · Apr 8

Postdoc opportunity in the heart of Europe! Check out the flyer below.
Join our team on an international project with Anthony Holtmaat exploring synaptic plasticity and specificity in cortical and thalamocortical circuits.

18 21

Giordano Lippi @lippilab.bsky.social · Apr 4

Thanks Eric!

1

Giordano Lippi @lippilab.bsky.social · Apr 4

Thank you NP

2

Reposted by Giordano Lippi

Scripps Research @scripps.edu · Apr 3

The Lipp Lab (@lippilab.bsky.social) has uncovered how microRNAs guide the development of Purkinje cells—rare neurons tied to movement and autism.

Published in Neuron, a @cellpress.bsky.social journal, the study maps how precise timing and gene regulation shape these cells’ identity and structure.

How microRNAs act as a “blueprint” for the developing brain

www.scripps.edu

3 22

Giordano Lippi @lippilab.bsky.social · Apr 3

😂

2

Giordano Lippi @lippilab.bsky.social · Apr 2

Very grateful to Bennie Babayan at @cp-neuron.bsky.social for a fantastic job as editor, and the funding that supported this project. NIH, @autismspeaks.org and @cziscience.bsky.social.

3

Giordano Lippi @lippilab.bsky.social · Apr 2

My favorite part is finding cell type-specific post-transcriptional mechanisms that drive morphological diversification among neurons. For example, strong repression in Purkinje cells of genes expressed also in pyramidal neurons is necessary for exuberant arborization! 🤯

1 2

Giordano Lippi @lippilab.bsky.social · Apr 2

Here is a link to the paper:
cell.com/neuron/fullt...

and to the press release from Scripps:
scripps.edu/news-and-event

MicroRNA mechanisms instructing Purkinje cell specification

Zolboot et al. introduce DD-T6B and SAP-seq, methods for investigating microRNA function with enhanced spatiotemporal resolution, and identify Purkinje cell-specific microRNAs and targets instructing ...

cell.com

1