eric lai
@lucksmith.bsky.social
study small RNAs/APA/splicing/m6A/Notch. neural development+behavior; genomic conflict+evolution.
http://www.mskcc.org/lai
also, indie rock and glassblowing.
http://www.mskcc.org/lai
also, indie rock and glassblowing.
unexpected collision of my two worlds this week: (1) thrilled to be enveloped by the mesmerizing vibes of the American Analog Set, 1st show in 20 years! (2) learned that Andrew Kenny, gtr/vox of AmAnSet and Wooden Birds, studied biochemistry and worked for years in fly RNA regulation! what?! 🎸+🪰+🧬=❤️
November 23, 2025 at 4:25 PM
unexpected collision of my two worlds this week: (1) thrilled to be enveloped by the mesmerizing vibes of the American Analog Set, 1st show in 20 years! (2) learned that Andrew Kenny, gtr/vox of AmAnSet and Wooden Birds, studied biochemistry and worked for years in fly RNA regulation! what?! 🎸+🪰+🧬=❤️
Reposted by eric lai
Boston's Mayor Wu playing with Yo-Yo Ma at Symphony Hall
November 23, 2025 at 5:11 AM
Boston's Mayor Wu playing with Yo-Yo Ma at Symphony Hall
having spent my early childhood in a tiny hockey town, watching the zamboni clean up the ice is one of most favoritist kid memories! 🧊
I checked:
There's no rule in hockey that a dinosaur can't drive a Zamboni.
Let's talk about Frank Zamboni's marvelous invention.
Frank was born in 1901 to Italian immigrant parents & raised on a farm in Lava Hot Springs, Idaho (ironically?).
There's no rule in hockey that a dinosaur can't drive a Zamboni.
Let's talk about Frank Zamboni's marvelous invention.
Frank was born in 1901 to Italian immigrant parents & raised on a farm in Lava Hot Springs, Idaho (ironically?).
a t-rex is sitting on the back of a truck that says derock demolition
Alt: a t-rex is sitting on the back of a Zamboni ice resurfacer that says derock demolition
media.tenor.com
November 22, 2025 at 4:59 PM
having spent my early childhood in a tiny hockey town, watching the zamboni clean up the ice is one of most favoritist kid memories! 🧊
Reposted by eric lai
No more paylines at the NIH
grants.nih.gov/news-events/...
grants.nih.gov/news-events/...
Implementing a Unified NIH Funding Strategy to Guide Consistent and Clearer Award Decisions | Grants & Funding
grants.nih.gov
November 21, 2025 at 7:45 PM
No more paylines at the NIH
grants.nih.gov/news-events/...
grants.nih.gov/news-events/...
AmAnSet gear. yours truly directly in front!
November 20, 2025 at 1:05 AM
AmAnSet gear. yours truly directly in front!
eagerly waiting the american analog set at pioneer works!!
November 20, 2025 at 12:51 AM
eagerly waiting the american analog set at pioneer works!!
you only feel alive when you're living on the edge!
ps, opportunity to share my PSA that the triangle on the pump icon tells you which side of the car your tank opens to. this way, you can easily know which way to pull up to the station, eg in an unfamiliar rental car.
ps, opportunity to share my PSA that the triangle on the pump icon tells you which side of the car your tank opens to. this way, you can easily know which way to pull up to the station, eg in an unfamiliar rental car.
November 19, 2025 at 2:47 PM
you only feel alive when you're living on the edge!
ps, opportunity to share my PSA that the triangle on the pump icon tells you which side of the car your tank opens to. this way, you can easily know which way to pull up to the station, eg in an unfamiliar rental car.
ps, opportunity to share my PSA that the triangle on the pump icon tells you which side of the car your tank opens to. this way, you can easily know which way to pull up to the station, eg in an unfamiliar rental car.
items for the top shelf of your bar: vintage can of pickup stix, little microscope with a creepy doll head on top of the eyepiece, big music box roll (?), fallout shelter sign. (ps this place was cozy and great for a date night!)
November 19, 2025 at 2:59 AM
items for the top shelf of your bar: vintage can of pickup stix, little microscope with a creepy doll head on top of the eyepiece, big music box roll (?), fallout shelter sign. (ps this place was cozy and great for a date night!)
thanks @davidlabmsk.bsky.social and Iestyn Whitehouse for organizing the Center of Epigenetics Research Symposium @mskcancercenter.bsky.social. packed a lot into one day, learned so much my head hurts. also, is it true that we just witnessed the last academic talk of Sir Tony Kouzarides?? wow.
November 18, 2025 at 12:13 AM
thanks @davidlabmsk.bsky.social and Iestyn Whitehouse for organizing the Center of Epigenetics Research Symposium @mskcancercenter.bsky.social. packed a lot into one day, learned so much my head hurts. also, is it true that we just witnessed the last academic talk of Sir Tony Kouzarides?? wow.
closing night of the blaze! 🎃
November 17, 2025 at 1:10 PM
closing night of the blaze! 🎃
i occasionally see the consolidated boiler service truck in the bronx. i always thought the thing on top was supposed to be a boiler. however, finally did some internet sleuthing this morning, and turns out it used to be A ROCKET!!! any new yorkers seen it back in the day? 🚀
consolidatedboiler.com
consolidatedboiler.com
November 15, 2025 at 2:16 PM
i occasionally see the consolidated boiler service truck in the bronx. i always thought the thing on top was supposed to be a boiler. however, finally did some internet sleuthing this morning, and turns out it used to be A ROCKET!!! any new yorkers seen it back in the day? 🚀
consolidatedboiler.com
consolidatedboiler.com
Reposted by eric lai
65 Years Ago,,, History was made. #RubyBridges
November 15, 2025 at 4:41 AM
65 Years Ago,,, History was made. #RubyBridges
Reposted by eric lai
BREAKING: In AAUP et al v. Trump (wall-to-wall union lawsuit challenging the administration’s unlawful use of TItle VI to reshape the University of California system), the faculty and staff of the UC system WON!!!
We were granted our preliminary injunction! @aaup.org
We were granted our preliminary injunction! @aaup.org
November 14, 2025 at 11:55 PM
BREAKING: In AAUP et al v. Trump (wall-to-wall union lawsuit challenging the administration’s unlawful use of TItle VI to reshape the University of California system), the faculty and staff of the UC system WON!!!
We were granted our preliminary injunction! @aaup.org
We were granted our preliminary injunction! @aaup.org
super news that Simons Foundation is hosting the next NY Area Pop Gen meeting March 9, 2026. I personally am also excited to finally have a new lab member working in this area so they are looking forward to interacting with this community!
Our NY area population genetics meeting is back and "upgraded", as Simons Foundation @simonsfoundation.org generously agreed to host. Please save the date: March 9, 2026. Look forward to seeing many of you from NY and beyond.
SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the
@simonsfoundation.org. Details to follow. Please RT.
@simonsfoundation.org. Details to follow. Please RT.
November 14, 2025 at 10:14 PM
super news that Simons Foundation is hosting the next NY Area Pop Gen meeting March 9, 2026. I personally am also excited to finally have a new lab member working in this area so they are looking forward to interacting with this community!
Reposted by eric lai
The main project of my postdoc with @spo11rulz.bsky.social is now available on bioRxiv! By systematically integrating structural information with molecular evolution analyses, we gained new fascinating insights into the evolution of key meiotic recombination proteins: www.biorxiv.org/content/10.1...
www.biorxiv.org
November 14, 2025 at 10:10 AM
The main project of my postdoc with @spo11rulz.bsky.social is now available on bioRxiv! By systematically integrating structural information with molecular evolution analyses, we gained new fascinating insights into the evolution of key meiotic recombination proteins: www.biorxiv.org/content/10.1...
Reposted by eric lai
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
U.S. Congress considers sweeping ban on Chinese collaborations
Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students
www.science.org
November 14, 2025 at 1:03 AM
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
v sad to hear Antonio García-Bellido's passing. his work on mitotic clones led to fundamental insights such as compartment boundaries, enabled post-embryonic analysis of lethals, and revealed autonomous vs non-autonomous effects of mutants. and founding father of Spanish DB and Drosophila schools.🪰
The European Drosophila Society #flyEDS extends the condolences on the passing of Antonio García-Bellido, considered the founder of the Spanish school of #Drosophila genetics and an influential figure in developmental biology research worldwide. May he rest in peace.
November 12, 2025 at 5:08 PM
v sad to hear Antonio García-Bellido's passing. his work on mitotic clones led to fundamental insights such as compartment boundaries, enabled post-embryonic analysis of lethals, and revealed autonomous vs non-autonomous effects of mutants. and founding father of Spanish DB and Drosophila schools.🪰
i love it when the morning emails include one that says "MANUSCRIPT ACCEPTED"!! (it wasn't actually in caps, that's just me shouting into the bluesky). let's gooooooo!!
November 12, 2025 at 2:57 PM
i love it when the morning emails include one that says "MANUSCRIPT ACCEPTED"!! (it wasn't actually in caps, that's just me shouting into the bluesky). let's gooooooo!!
Reposted by eric lai
Breaking News: The Supreme Court denied a request to consider overturning its landmark decision to legalize same-sex marriage a decade ago. nyti.ms/3Ju2Ayd
November 10, 2025 at 2:51 PM
Breaking News: The Supreme Court denied a request to consider overturning its landmark decision to legalize same-sex marriage a decade ago. nyti.ms/3Ju2Ayd
new Lai lab paper @natsmb.nature.com! Dicer is specifically mutated in cancer, but we don't fully understand its molecular/reg impacts. with @danweihuangfu.bsky.social, we characterized the first knockin Dicer hotspot in hESCs, and found unexpected defects in miRNA biogenesis! 🧬 1/4
rdcu.be/eOc0q
rdcu.be/eOc0q
Human DICER1 hotspot mutation induces both loss and gain of miRNA function
Nature Structural & Molecular Biology - Jee et al. study a cancer hotspot allele of DICER1 that disrupts RNaseIIIb activity. Beyond ablating 5p hairpin cleavage, 3p passenger strands are...
rdcu.be
November 10, 2025 at 4:43 PM
new Lai lab paper @natsmb.nature.com! Dicer is specifically mutated in cancer, but we don't fully understand its molecular/reg impacts. with @danweihuangfu.bsky.social, we characterized the first knockin Dicer hotspot in hESCs, and found unexpected defects in miRNA biogenesis! 🧬 1/4
rdcu.be/eOc0q
rdcu.be/eOc0q
finally made it to sunshine laundromat. in the back beyond this door is a pinball bar!! (inc special edition addams family, which i've never seen/played).
November 9, 2025 at 7:34 PM
finally made it to sunshine laundromat. in the back beyond this door is a pinball bar!! (inc special edition addams family, which i've never seen/played).
ladies and gentlemen there will be a delay
November 9, 2025 at 4:49 PM
ladies and gentlemen there will be a delay
startled to see this in the closet at the gym
November 9, 2025 at 2:02 PM
startled to see this in the closet at the gym
as my friend points out, the blizzard logo on the upside-down blizzard pic is actually upside-down.
November 8, 2025 at 9:36 PM
as my friend points out, the blizzard logo on the upside-down blizzard pic is actually upside-down.