Jan Mašek
@maseklab.bsky.social
PI at CUNI Prague🇨🇿, Karolinska Institutet🇸🇪, Czexpat🌍, Junior Faculty chair. Notch & Wnt in development and disease 🔬🧫🐁. *All views my own; 🇪🇺🇺🇦 https://maseklab.org
Pinned
Paper alert! 🤓 Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It's called crosstalk. But doesn't it defy the logic of clear communication channels between cells? 🧐
Reposted by Jan Mašek
Today at PI_Forum Brno we will discuss this graph.
From 62% women at PhD level to 17% at professor level.
Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social
From 62% women at PhD level to 17% at professor level.
Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social
February 3, 2026 at 7:51 AM
Today at PI_Forum Brno we will discuss this graph.
From 62% women at PhD level to 17% at professor level.
Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social
From 62% women at PhD level to 17% at professor level.
Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social
Paper alert! 🤓 Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It's called crosstalk. But doesn't it defy the logic of clear communication channels between cells? 🧐
January 27, 2026 at 3:22 PM
Paper alert! 🤓 Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It's called crosstalk. But doesn't it defy the logic of clear communication channels between cells? 🧐
Reposted by Jan Mašek
Author copies of our new book on statistics (mainly) for life scientists arrived recently. After three years of work, this is exciting, especially as we really hope it can help make a positive difference.
What's so special about it?
🧵
What's so special about it?
🧵
December 9, 2025 at 1:49 PM
Author copies of our new book on statistics (mainly) for life scientists arrived recently. After three years of work, this is exciting, especially as we really hope it can help make a positive difference.
What's so special about it?
🧵
What's so special about it?
🧵
Great article about starting a lab at @sciencecharles.bsky.social and the positive effect of supportive peer community from my colleague and co-chair of JF Vito @geohazards.group. For more context check also my article in @vedavyzkumcz.bsky.social - vedavyzkum.cz/nazory/nazor....
Our article on the #JuniorFaculty initiative is now online!
‘Anyone hired a student before?’ How a group of novice lab leaders are supporting each other www.nature.com/articles/d41...
‘Anyone hired a student before?’ How a group of novice lab leaders are supporting each other www.nature.com/articles/d41...
‘Anyone hired a student before?’ How a group of novice lab leaders are supporting each other
By creating a network of early-career principal investigators, my colleagues and I have enacted change and battled bureaucracy.
www.nature.com
December 3, 2025 at 11:59 PM
Great article about starting a lab at @sciencecharles.bsky.social and the positive effect of supportive peer community from my colleague and co-chair of JF Vito @geohazards.group. For more context check also my article in @vedavyzkumcz.bsky.social - vedavyzkum.cz/nazory/nazor....
15th PhD Conference in Dev Cell biology just started and it looks like another year packed with great science, opening with brilliant @ruibenedito.bsky.social keynote!
October 22, 2025 at 8:01 AM
15th PhD Conference in Dev Cell biology just started and it looks like another year packed with great science, opening with brilliant @ruibenedito.bsky.social keynote!
Reposted by Jan Mašek
👩🔬👨💻 Postdoc recruitment! 👨🔬👩💻
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Postdoctoral studies in next generation single cell lineage tracing of skin (scholarship)
Do you want to contribute to top quality medical research? A postdoctoral scholarship is available in the lab of Emma R Andersson at the Department of Cell and Molecular Biology, Karolinska Institutet
ki.varbi.com
September 27, 2025 at 7:41 AM
👩🔬👨💻 Postdoc recruitment! 👨🔬👩💻
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Reposted by Jan Mašek
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
September 15, 2025 at 5:26 PM
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
Reposted by Jan Mašek
🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
Scientific bedlam at the world’s weirdest and wildest research conference
Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.
www.nature.com
July 31, 2025 at 4:22 AM
🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
Reposted by Jan Mašek
Read all Elements in The Philosophy of Biology series for FREE during the ISHPSSB conference 20 - 25 July. You can find all of these Elements free to download and read here: cup.org/4kEgivL
Philosophy of Biology
Welcome to Cambridge Core
cup.org
July 20, 2025 at 5:16 PM
Read all Elements in The Philosophy of Biology series for FREE during the ISHPSSB conference 20 - 25 July. You can find all of these Elements free to download and read here: cup.org/4kEgivL
Reposted by Jan Mašek
We should have the equivalent for PIs looking for students and/or postdocs
go.bsky.app/8zZNEGV
Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪
Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪
July 17, 2025 at 12:40 PM
We should have the equivalent for PIs looking for students and/or postdocs
Reposted by Jan Mašek
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
FDA-NIH Workshop: Reducing Animal Testing
The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.
tinyurl.com
July 11, 2025 at 5:22 PM
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
Reposted by Jan Mašek
Reposted by Jan Mašek
Read this piece. It gives a great impression of #TCTeAC WoodstockBio2 & Night Science from one of the #Instigators. This is the next best thing to being there... I like the expression #BohemianFixers. Many thanks to them! Děkujeme.
thenode.biologists.com/from-posters...
thenode.biologists.com/from-posters...
From Posters to Parades: Inside Woodstock.Bio² & Night Science Conference - the Node
A fever dream of science and spirit wrapped in the forests of Bohemia. Here’s an escalating list — starting with the standard (though nothing was standard
thenode.biologists.com
June 26, 2025 at 12:13 PM
Read this piece. It gives a great impression of #TCTeAC WoodstockBio2 & Night Science from one of the #Instigators. This is the next best thing to being there... I like the expression #BohemianFixers. Many thanks to them! Děkujeme.
thenode.biologists.com/from-posters...
thenode.biologists.com/from-posters...
Reposted by Jan Mašek
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
June 26, 2025 at 8:15 AM
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
Reposted by Jan Mašek
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
June 16, 2025 at 12:19 PM
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
Reposted by Jan Mašek
This might be useful for the #TCTeAC participants 🇨🇿, 🙏 @svobodalab.bsky.social @odedrechavi.bsky.social @itaiyanai.bsky.social go.bsky.app/DPH6r8o
June 13, 2025 at 1:24 PM
This might be useful for the #TCTeAC participants 🇨🇿, 🙏 @svobodalab.bsky.social @odedrechavi.bsky.social @itaiyanai.bsky.social go.bsky.app/DPH6r8o
Super nice talk by @jesseveenvliet.bsky.social on how the environment restricts the possible courses of embryonic development 🤓 #TCTeAC
June 11, 2025 at 10:18 AM
Super nice talk by @jesseveenvliet.bsky.social on how the environment restricts the possible courses of embryonic development 🤓 #TCTeAC
@honzadobes87.bsky.social nailing his talk at WoB2 conference #TCTeAC
June 11, 2025 at 8:10 AM
@honzadobes87.bsky.social nailing his talk at WoB2 conference #TCTeAC
Reposted by Jan Mašek
📣Check out our recent review (written with Martina Huranova lab) on converging mechanisms controlling #cilia #dynamics during #cell #cycle, #cell #signaling, and cross-talk of ciliary modules.
rdcu.be/epVDc
rdcu.be/epVDc
Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle
rdcu.be
June 10, 2025 at 6:35 AM
📣Check out our recent review (written with Martina Huranova lab) on converging mechanisms controlling #cilia #dynamics during #cell #cycle, #cell #signaling, and cross-talk of ciliary modules.
rdcu.be/epVDc
rdcu.be/epVDc
Reposted by Jan Mašek
English-speaking colleagues welcome!
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
May 18, 2025 at 10:35 AM
English-speaking colleagues welcome!
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
Reposted by Jan Mašek
Let's talk about a party—where drugs don't hit the dance floor but finely tune #EpithelialMechanics by hitting actomyosin cortex! 🧬💊
Here's our guide to doing drugs 🧵
Here's our guide to doing drugs 🧵
May 18, 2025 at 2:19 AM
Let's talk about a party—where drugs don't hit the dance floor but finely tune #EpithelialMechanics by hitting actomyosin cortex! 🧬💊
Here's our guide to doing drugs 🧵
Here's our guide to doing drugs 🧵
Reposted by Jan Mašek
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 1, 2025 at 7:32 AM
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
Reposted by Jan Mašek
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes
www.pnas.org
May 12, 2025 at 7:33 AM
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
Reposted by Jan Mašek
🌟 #PI_Forum Brno #5: Academic Leadership: The Big Picture is ahead!
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
April 30, 2025 at 8:34 AM
🌟 #PI_Forum Brno #5: Academic Leadership: The Big Picture is ahead!
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...