Maurice Lab
@mauricelab.bsky.social
67 followers
51 following
8 posts
Exploring the dual nature of signals, particularly Wnt signaling, in homeostasis and cancer using organoids and proteomics to uncover patient-specific mechanisms. Founder of Laigo Bio.
Center for Molecular Medicine | Oncode Institute | madelonmauricelab.nl
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Maurice Lab
@mauricelab.bsky.social
· Jan 29
✨ New #Review ✨
@madelonmaurice.bsky.social & Stephane Angers discuss the newest insights on #WntSignalling with a focus on biogenesis & transport of Wnts and Wnt receptor complex activation.
👉 go.nature.com/42ynuU0
@madelonmaurice.bsky.social & Stephane Angers discuss the newest insights on #WntSignalling with a focus on biogenesis & transport of Wnts and Wnt receptor complex activation.
👉 go.nature.com/42ynuU0
Mechanistic insights into Wnt–β-catenin pathway activation and signal transduction - Nature Reviews Molecular Cell Biology
Wnt–β-catenin signalling regulates stem cell renewal, development and tissue homeostasis. In this Review, the authors examine recent findings concerning Wnt protein production, receptor activation and...
go.nature.com
Maurice Lab
@mauricelab.bsky.social
· Dec 22
Maurice Lab
@mauricelab.bsky.social
· Dec 22
WNT7B drives a program for pancreatic cancer subtype switching and progression
Hyperactivation of WNT signaling is a well-established hallmark of cancer. Various epithelial cancers express high levels of WNT7B and WNT10A that are not commonly expressed during tissue homeostasis,...
www.biorxiv.org
Maurice Lab
@mauricelab.bsky.social
· Dec 9