Maurice Lab
banner
mauricelab.bsky.social
Maurice Lab
@mauricelab.bsky.social
67 followers 51 following 8 posts
Exploring the dual nature of signals, particularly Wnt signaling, in homeostasis and cancer using organoids and proteomics to uncover patient-specific mechanisms. Founder of Laigo Bio. Center for Molecular Medicine | Oncode Institute | madelonmauricelab.nl
Posts Media Videos Starter Packs
Jelte van der Vaart, postdoc in our lab, has been awarded an NWO Veni grant! 🎉
He will develop human adrenal organoids to uncover how hormone producing cells change identity and function, shedding light on endocrine health.
We're so proud of his achievement and will support him along the way 😁
Yesterday, @antonvenhuizen.bsky.social successfully defended his thesis "Molecular mechanisms of the
β-catenin destruction complex in health and disease", which describes the versatile field of WNT regulator AXIN1.

We are super proud and wish Dr. Venhuizen all the best in Cambridge!
Reposted by Maurice Lab
Our Center for Molecular Medicine (cmmutrecht.eu) at UMC Utrecht, NL, is looking for a Principal Investigator in the field of fundamental Cancer Biology! The vacancy states tenure track level, but candidates with a more advanced career are very welcome to apply. shorturl.at/KZeYQ. Please repost!
Center for Molecular Medicine
cmmutrecht.eu
Great work by @joepsprangers.bsky.social and more members from the lab! And that 3 days after receiving his doctorate!!!🎓
Pre-print Alert! 📢
Proud to share our insights on WNT7B driving pancreatic cancer progression. Sprangers et al uses organoids to show that WNT7B employs short-range signaling driving tumor growth and mediate a shift of PDAC cells towards a more aggressive phenotype

www.biorxiv.org/content/10.1...
WNT7B drives a program for pancreatic cancer subtype switching and progression
Hyperactivation of WNT signaling is a well-established hallmark of cancer. Various epithelial cancers express high levels of WNT7B and WNT10A that are not commonly expressed during tissue homeostasis,...
www.biorxiv.org
🎉 Huge congratulations to Dr. Joep Sprangers! Yesterday, Joep successfully defended his PhD thesis and officially became a doctor! His studies describe the role of WNT7B and WNT10A in regeneration, homeostasis, and cancer.
It was a very special day, couldn’t be prouder.
Yesterday, our lab turned festive for late Sinterklaas/early Christmas! 🎁 With poems, laughter, and guessing games, we shared stories, gifts, and some surprising personal details. Add drinks, snacks, and a digital fireplace, and it was a night of bonding, cheer, and fun!✨#LifeOutsideTheLab
Our first post on BlueSky is here 🦋. Great story from @antonvenhuizen.bsky.social from our lab describing the role of AXIN1 mutations in hepatocellular carcinoma. Congrats to Anton for the hard work and the deserved BioRxiv pre-publication! 🥳

www.biorxiv.org/content/10.1...