Reposted by Merve Nur Güler
In our new study, we investigate how GWAS test statistics behave when a trait’s genetic architecture includes epistasis. We first model the bias mathematically and show via simulations how linear models can produce spurious significance (more in comments).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Bias in genome-wide association test statistics due to omitted interactions
Over the past two decades, genome-wide association studies (GWAS) enabled the discovery of thousands of variants associated with many complex human traits. However, conventional GWAS are still widely ...
www.biorxiv.org
November 23, 2025 at 10:43 AM
In our new study, we investigate how GWAS test statistics behave when a trait’s genetic architecture includes epistasis. We first model the bias mathematically and show via simulations how linear models can produce spurious significance (more in comments).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
I am happy and honoured to share that I won the Grand Prize in the Artur Lind Scholarship video competition at the Gene Forum 2025. 🎉
September 12, 2025 at 9:29 AM
I am happy and honoured to share that I won the Grand Prize in the Artur Lind Scholarship video competition at the Gene Forum 2025. 🎉
Our genetic kinship estimation tool “DeepKin” is now available! Our neural network models trained on simulated data work effectively on real ancient data from diverse backgrounds and often outperform available tools. @compevohumang.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
DeepKin: Predicting Relatedness From Low‐Coverage Genomes and Palaeogenomes With Convolutional Neural Networks
DeepKin is a novel tool designed to predict relatedness from genomic data using convolutional neural networks (CNNs). Traditional methods for estimating relatedness often struggle when genomic data i...
onlinelibrary.wiley.com
August 18, 2025 at 12:07 PM
Our genetic kinship estimation tool “DeepKin” is now available! Our neural network models trained on simulated data work effectively on real ancient data from diverse backgrounds and often outperform available tools. @compevohumang.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
Happy to share our new study I contributed to during my master’s: "Female lineages and changing kinship patterns in Neolithic Çatalhöyük." @compevohumang.bsky.social
Female lineages and changing kinship patterns in Neolithic Çatalhöyük
Combining 131 paleogenomes with bioarchaeological and archaeological data, we studied social organization and gendered practices in Çatalhöyük East Mound (7100 to 5950 BCE), a major Neolithic settleme...
www.science.org
June 27, 2025 at 6:54 AM
Happy to share our new study I contributed to during my master’s: "Female lineages and changing kinship patterns in Neolithic Çatalhöyük." @compevohumang.bsky.social
Reposted by Merve Nur Güler
Excited to share our recently published overview of the @estbiobank.bsky.social 🧬
We highlight the unique features of the biobank and the conducted scientific research it has enabled, including the many recall studies that have been carried out over the years!
www.nature.com/articles/s41...
We highlight the unique features of the biobank and the conducted scientific research it has enabled, including the many recall studies that have been carried out over the years!
www.nature.com/articles/s41...
The Estonian Biobank’s journey from biobanking to personalized medicine - Nature Communications
Large-scale biobanks have become a font of data that have led to discoveries across many fields of research. Here, the authors provide an overview of the Estonian Biobank, highlighting its value for r...
www.nature.com
April 7, 2025 at 9:13 AM
Excited to share our recently published overview of the @estbiobank.bsky.social 🧬
We highlight the unique features of the biobank and the conducted scientific research it has enabled, including the many recall studies that have been carried out over the years!
www.nature.com/articles/s41...
We highlight the unique features of the biobank and the conducted scientific research it has enabled, including the many recall studies that have been carried out over the years!
www.nature.com/articles/s41...