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Michelle Lupton

@michelleklupton.bsky.social

26 followers 75 following 5 posts

Head of the Neurogenetics and Dementia group at QIMR Berghofer @qimrb.bsky.social

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Michelle Lupton @michelleklupton.bsky.social · 2d

Our newest preprint is now available, using Mendelian randomisation to investigate the causal relationship between Frailty and Alzheimer's disease. www.medrxiv.org/content/10.1...
Awesome work from our visiting PhD student Jonny Flint #NGDgroup

Domains of Frailty as Early Risk Factors for Alzheimer Dementia - Genetic and Causal Evidence

Background Alzheimer’s dementia (AD) is a leading cause of disability and dependency in older adults. Frailty is a phenotypic risk factor for AD, but its causal role remains unclear - partly due to re...

www.medrxiv.org

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Michelle Lupton @michelleklupton.bsky.social · May 29

If you are heading to the ADRF conference in Perth next week, come along to our special research session for the DEMON Network on "The convergence of traditional and digital biomarkers: A new era for Alzheimer’s disease diagnostics?"

Michelle Lupton @michelleklupton.bsky.social · May 20

We contributed data to the largest GWAS of personality traits, available in preprint. #PISA_DementiaStudy #NGDgroup

Ted Schwaba @tedmond.bsky.social · May 20

Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...

Michelle Lupton @michelleklupton.bsky.social · Apr 13

Proud to have contributed data to the largest GWAS of osteoarthritis, highlighting disease pathways and potential drug targets #PISA_DementiaStudy #NGDgroup rdcu.be/ehycr

Translational genomics of osteoarthritis in 1,962,069 individuals

Nature - A genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of...

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Michelle Lupton @michelleklupton.bsky.social · Nov 12

Our latest Paper from #PISA_DementiaStudy #NGDgroup

Renate Thienel (PhD, MPsych) @rthienel.bsky.social · Nov 11

Cortical and cognitive profiles reveal intricate interactions among factors that shape cognition and brain structure from mid-life onward, offering critical insights for advancing neurodegeneration research and improving future screening algorithms.
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The interplay of age, gender and amyloid on brain and cognition in mid-life and older adults

Scientific Reports - The interplay of age, gender and amyloid on brain and cognition in mid-life and older adults

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