@mikesleutel.bsky.social
For over 100 years, Bt spores have been used to protect crops from caterpillars. These spores bear mysterious hair-like ENAs. Thanks to cryoEM, we now know ENAs are robust protein fibers that cluster spores like grappling hooks. Read more in Nature Communications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cryo-EM identifies F-ENA of Bacillus thuringiensis as a widespread family of endospore appendages across Firmicutes - Nature Communications
B. thuringiensis spores contain uncharacterized protein filaments that extend from the surface of the exosporium. Here, the authors show that these filaments feature conserved β-barrel neck domains an...
www.nature.com
August 16, 2025 at 7:03 PM
For over 100 years, Bt spores have been used to protect crops from caterpillars. These spores bear mysterious hair-like ENAs. Thanks to cryoEM, we now know ENAs are robust protein fibers that cluster spores like grappling hooks. Read more in Nature Communications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Happy to see the final version out! Cryo-EM structure of the PS2 S-layer in Corynebacterium 🔬! We show it provides mechanical support to the cell wall and assembles at the poles in coordination with PG. It can also be used for covalent surface display.
www.pnas.org/doi/10.1073/...
#microsky
www.pnas.org/doi/10.1073/...
#microsky
Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum | PNAS
The polar-growing Corynebacteriales have a complex cell envelope architecture characterized
by the presence of a specialized outer membrane compose...
www.pnas.org
July 30, 2025 at 4:50 AM
Happy to see the final version out! Cryo-EM structure of the PS2 S-layer in Corynebacterium 🔬! We show it provides mechanical support to the cell wall and assembles at the poles in coordination with PG. It can also be used for covalent surface display.
www.pnas.org/doi/10.1073/...
#microsky
www.pnas.org/doi/10.1073/...
#microsky
In our latest preprint we used cryoEM to solve the structure of A-ENA fibers and show that they are stabilized by 10 isopeptide bonds per monomer. A-ENA couples the spore to the cry-toxins, and in doing so increases the virulence of Bacillus thuringiensis: www.researchsquare.com/article/rs-6...
May 20, 2025 at 9:22 AM
In our latest preprint we used cryoEM to solve the structure of A-ENA fibers and show that they are stabilized by 10 isopeptide bonds per monomer. A-ENA couples the spore to the cry-toxins, and in doing so increases the virulence of Bacillus thuringiensis: www.researchsquare.com/article/rs-6...