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Mike Waring @mikewaring.bsky.social · Jun 13

New paper: We've always used TPGS in our micellar #DEL synthesis. This paper shows you can find better ones using @baonguyengroup.bsky.social surfactant map. Great work from Jake Odger et al pubs.rsc.org/en/Content/A...

Improvements in micelle promoted DNA-encoded library synthesis by surfactant optimisation

DNA-encoded libraries are increasingly important in hit identification at the early stage of the drug discovery process. The approach relies on efficient methods for synthesis of drug-like compounds a...

pubs.rsc.org

Mike Waring @mikewaring.bsky.social · Jun 9

Something makes me think that this invite might have been autogenerated...

Reposted by Mike Waring

CRUK Newcastle Drug Discovery Group @nudrugdiscovery.bsky.social · May 13

It's official, our med chem Senior Research Associate @hannahstewart92.bsky.social is the world's fastest scientist @guinnessworldrecords.com guinnessworldrecords.com/world-record...

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Mike Waring @mikewaring.bsky.social · Apr 15

Starting the @mosmedcdt.bsky.social conference. It will get better from here!

Newcastle Chemistry @chemistryncl.bsky.social · Apr 15

Great start to the @mosmedcdt.bsky.social CDT conference in Durham from director @mikewaring.bsky.social. Welcome to all the students, supervisors & industry partners in attendance!

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Mike Waring @mikewaring.bsky.social · Apr 11

Group trip to the pub / watch the bins being emptied.

Mike Waring @mikewaring.bsky.social · Apr 10

This work also provides some hopefully useful information on how to generate and interpret SAR of covalent inhibitors.

Mike Waring @mikewaring.bsky.social · Apr 10

New paper published today describing some SAR on EGFR inhibitors including an interesting effect of a pair of enantiomers on covalent biinding www.nature.com/articles/s42...

Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding - Communications Chemistry

Covalent inhibitors are a successful class of drugs, however, the optimization of targeted covalent inhibitors has challenges due to the need to increase non-covalent interactions and modulate reactiv...

www.nature.com

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Apr 7

Prof. Mike Waring (@mikewaring.bsky.social), Chair of Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Apr 2

Nikol Zografou Barredo, PhD Student (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Mar 31

Dr Hannah Stewart (@hannahstewart92.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Mar 17

Dr Harriet Stanway-Gordon (@harrietsg.bsky.social), Research Fellow (Medicinal Chemistry/Chemical Biology), Newcastle University #facesofscience #chemsky #sciencesky

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Mike Waring @mikewaring.bsky.social · Mar 14

Highlighting scientists and the possibility that they may also be humans, give them a follow bsky.app/profile/face...

bsky.app

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Mar 3

COMING SOON! Sneak preview of the selection of people we're showcasing this month 🧪

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Mar 5

Dr Celine Cano, Reader in Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Mar 10

Dr Grace Roper, PDRA (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

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Reposted by Mike Waring

Faces of Science @facesofscience.bsky.social · Mar 12

Dr Suzannah Harnor (@sjharnor.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

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Mike Waring @mikewaring.bsky.social · Mar 10

We have a PhD studentship in the @nudrugdiscovery.bsky.social @chemistryncl.bsky.social with me and @hannahstewart92.bsky.social to develop methods of making macrocycles as a new class of antimicrobial agents. Apply at the link and contact us if you have questions. www.findaphd.com/phds/project...

A Build-couple-transform approach to diverse macrocyclic libraries for antimicrobial drug discovery. at Newcastle University on FindAPhD.com

PhD Project - A Build-couple-transform approach to diverse macrocyclic libraries for antimicrobial drug discovery. at Newcastle University, listed on FindAPhD.com

www.findaphd.com

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Mike Waring @mikewaring.bsky.social · Mar 6

Check out RSC Medicinal Chemistry now on Bluesky @rscmedchem.rsc.org

bsky.app

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Mike Waring @mikewaring.bsky.social · Feb 22

Yesterday Julian Knight officially retired from @chemistryncl.bsky.social Julian is a brilliant organic chemistry lecturer and will be sorely missed

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Mike Waring @mikewaring.bsky.social · Feb 8

Congratulations to Dr Matt Anderson on passing his PhD viva yesterday. @chemistryncl.bsky.social @nudrugdiscovery.bsky.social

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Mike Waring @mikewaring.bsky.social · Jan 31

We have a #PhDstudentship starting in Sept with me and @hannahstewart92.bsky.social ideal for candidates with interest in research in #medicinalchemistry and #organicsynthesis
Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...

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Reposted by Mike Waring

CRUK Newcastle Drug Discovery Group @nudrugdiscovery.bsky.social · Dec 27

Read about our potential breakthrough in oncology - restoring wild type p53 function with ASTX295. This molecule was co-developed with Astex Pharmaceuticals, and is currently showing great phase I trial readout! #cancer #medchem #clinicaltrials

www.linkedin.com/posts/cancer...

Cancer Research Horizons on LinkedIn: #onmyhorizon #cancerresearch

2024 milestones worth celebrating 🧬🌟 Bravo to the incredible researchers at the Drug Discovery Unit at Newcastle University. They've unlocked a potential…

www.linkedin.com

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Reposted by Mike Waring

CRUK Newcastle Drug Discovery Group @nudrugdiscovery.bsky.social · Dec 19

Our research is critically dependent on funding we receive from @cancerresearchuk.org and we are also willing to do our bit towards fundraising. In 2024:
Funds Raised: £6,440 (+£1,031 gift aid)
Online Donations: 283
Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz

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Reposted by Mike Waring

Ute Jungwirth @utejungwirth.bsky.social · Dec 13

Exciting collaboration from our @nudrugdiscovery.bsky.social team
@newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌

CRUK Newcastle Drug Discovery Group @nudrugdiscovery.bsky.social · Dec 13

Thrilled to share the new collaboration between @diamondlightsource.bsky.social + @crhorizons.bsky.social + @newcastleuni.bsky.social to accelerate structure-based drug development via fragment screening! More here: bit.ly/4g7Et3f 🧬🧶 #chemsky #chembio We're already hard at work on exciting targets 💪

Cancer Research Horizons and Diamond Light Source establish drug discovery partnership

Cancer Research Horizons is partnering with Diamond Light Source, the UK’s national synchrotron, to build a world-leading fragment-based drug discovery programme.

bit.ly

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Mike Waring @mikewaring.bsky.social · Nov 29

Looking forward to speaking at the #scireviewmeeting next week. Some interesting topics...

30th SCI Annual Review Meeting – New Directions in Organic Chemistry

The 30th Annual Review Meeting – New Directions in Organic Chemistry, organised by SCI's Young Chemists’ Panel, will address key areas of contemporary synthetic organic chemistry.

www.soci.org

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