Lightnews — Scholar-powered news

Mission Bio @missionbio.bsky.social · Sep 3

Thanks for posting, Lars!

Mission Bio @missionbio.bsky.social · Sep 3

To overcome cellular heterogeneity, the critical challenge driving drug resistance in oncology and impacting safety in cell & gene therapy, targeted single-cell DNA and RNA analysis is the key to linking genetic drivers to their functional expression in every cell.

missionbio.com/company/blog...

Pharma Assay Development with Single-Cell Targeted DNA + RNA Analysis. | Mission Bio

De-risk drug development and cell & gene therapies with targeted single-cell multi-omics linking genomics with gene expression data leveraging Mission Bio’s Pharma Assay Development (PAD) services.

missionbio.com

1

Mission Bio @missionbio.bsky.social · Aug 25

[Open Paper] Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing.

bmccancer.biomedcentral.com/articles/10....

Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing - BMC Cancer

Background Cutaneous squamous cell carcinoma (CSCC) is a prevalent skin cancer with aggressive progression that poses significant challenges, especially in metastatic cases. Single-cell DNA sequencing...

bmccancer.biomedcentral.com

Mission Bio @missionbio.bsky.social · Aug 21

www.youtube.com/shorts/e9nYe...

What is Single-Cell Multiomics?

YouTube video by Mission Bio

www.youtube.com

Mission Bio @missionbio.bsky.social · Aug 19

In this blog post, discover how single-cell multi-omics helps you see what bulk methods miss. By linking DNA, RNA, and protein in the same cell, researchers can spot relapse earlier, follow clonal evolution, & shape better therapies for cancer and cell & gene therapy. missionbio.com/company/blog...

An image, where the background image is a DNA protein. The image reads "What is single-cell multi-omits?" which is the title of the blog the post is linked to.

Mission Bio @missionbio.bsky.social · Aug 6

🚨 [New Blog] 🚨 Discover how by combining single-cell targeted DNA and RNA analysis, Mission Bio’s Tapestri platform now lets researchers connect genotype with function for a more complete view of disease biology.

🖊️ - Authored by Jacqueline Marin

Read here: missionbio.com/company/blog...

1

Mission Bio @missionbio.bsky.social · Aug 5

📣 [New Press Release] - Mission Bio is accelerating the development of single-cell tri-omics to unlock deeper insights in cancer research and treatment.

Read the full release here: missionbio.com/press/equity...

Mission Bio Secures Equity Financing to Accelerate Single-Cell Trio-mics Platform Expansion. Image of Mission Bio Tapestri Instrument.

1

Mission Bio @missionbio.bsky.social · Jun 18

Last call for savings! 📣

Mission Bio is offering limited-time discounts on Tapestri® kits and warranties to help academic and non-profit labs stretch their budgets further — and still generate high-impact single-cell data.

Learn more 👉 bit.ly/453RcBr

Mission Bio @missionbio.bsky.social · Jun 5

We're excited to announce our newest advancement in precision oncology: the Single-Cell Genotype and Targeted Gene Expression assay! This solution enables simultaneous profiling of genotype and targeted gene expression in over 10,000 cells 🎉

Learn more ➡️ bit.ly/4ktWgUE

1

Mission Bio @missionbio.bsky.social · Jun 4

💸Budget tight? We’ve got your back.

Mission Bio is offering limited-time discounts on Tapestri® kits and warranties to help academic and non-profit labs stretch their budgets further — and still generate high-impact single-cell data.

Learn more 👉 bit.ly/453RcBr

Mission Bio @missionbio.bsky.social · May 21

Published today in @nature.com, researchers from @crg.eu and @irbbarcelona.org utilized Tapestri to develop EPI-clone, which tracks clonal dynamics in hematopoiesis with naturally occurring DNA methylation patterns.

Learn more here ➡️ bit.ly/4drZc12

Nature Publication Shows Mission Bio's Tapestri® Platform Enables Real-Time, Single-Cell Tracking of Precancerous Clones Using Natural Epigenetic Markers | Mission Bio

Epigenetic barcoding incorporating Tapestri unlocks high-throughput single-cell lineage tracing of clonality with or without mutation drivers, a previously invisible precursor to cancer development EP...

bit.ly

2 3

Mission Bio @missionbio.bsky.social · May 14

#ASGCT2025 is in full swing! We're having a blast in New Orleans meeting everyone and sharing how Tapestri is advancing genome editing validation with single-cell precision.

Swing by Booth #1749 to say hello to our team! 👋

Mission Bio @missionbio.bsky.social · May 13

At #ASGCT2025? Don’t miss our poster on advancing genome editing validation with single-cell precision

🧬 Comprehensive On- and Off-target Validation Using Integrated rhAmpSeq and Targeted DNA Resequencing Single-Cell Technology

📅 May 15 | 5:30 PM CT

Learn more here ➡️ bit.ly/4jS33Hc

Mission Bio @missionbio.bsky.social · May 8

🎉 We're headed to the Big Easy! Join us next week in New Orleans for @asgct.bsky.social #ASGCT2025 🎉

Visit Mission Bio at Booth #1749 to learn more about how Tapestri is advancing #cgt characterization 🧬

Check out the *can't-miss* oral and poster presentations here ➡️ bit.ly/3SrruPD

Mission Bio @missionbio.bsky.social · May 6

Our partnership with Integrated DNA Technologies is built on the principle of therapeutic safety— bringing single-cell resolution and unmatched precision to genome editing analysis.

Read the full story here 👉 bit.ly/3GBbCro

Mission Bio @missionbio.bsky.social · Apr 17

Bulk sequencing and traditional assays miss critical details that impact the safety and efficacy of cell therapies. 🧐

With the Tapestri, you can interrogate zygosity, detect off-target effects, and assess immunophenotype—all in one assay.

Learn more ➡️ bit.ly/42kjBS5

Mission Bio @missionbio.bsky.social · Apr 16

Our team is having an *AWSOM* time in Atlanta today at the 4th annual Atlanta Workshop of Single-cell Omics. If you're attending, be sure to swing by our table to say hi! 👋

Learn more about the Tapestri platform here ➡️ missionbio.com/products/pla...

Mission Bio @missionbio.bsky.social · Apr 10

Actionable Insights, Accelerated Outcomes 💪

Get the right drug to market faster with PAD services. Learn more about PAD services for drug development here ➡️ bit.ly/4ia8uj2

1

Mission Bio @missionbio.bsky.social · Apr 1

Your partner at every step 🤝

From assay design to sample analysis and data interpretation, the PAD Services Team is here to help.

Learn more ➡️ bit.ly/3FLtsYj

1

Mission Bio @missionbio.bsky.social · Feb 26

🚨 Last chance to register!🚨 Join us tomorrow to learn how researchers from @cincychildrens.bsky.social utilized single-cell DNA + Fusion multi-omic analysis for acute leukemias

📅 Thursday, February 27
⏰ 11:30a ET | 8:30a PT

Register here ➡️ bit.ly/4131uPD

Mission Bio @missionbio.bsky.social · Feb 6

[Live Webinar] Learn how researchers from @cincychildrens.bsky.social utilized single-cell DNA + Fusion multi-omic analysis for acute leukemias

📅 Thursday, February 27
⏰ 11:30a ET | 8:30a PT

Register now to save your spot! ➡️ bit.ly/4131uPD

Mission Bio @missionbio.bsky.social · Jan 14

📌 📅 Save the date! Join us Thursday, January 30 for a live webinar with Dr. Nils Wellhausen of @upenn.edu School of Medicine. He'll be discussing how epitope editing enables safe, CD45-directed CAR-T therapies for blood cancers.

Register here ➡️ missionbio.zoom.us/webinar/regi...