🚀New preprint w/ @roberto_amv: We used chemogenetics to precisely control mitochondrial H2O2 in skeletal muscle in vivo. This exposes a dose-dependent sequence: translation suppression → proteolysis → denervation-like → degeneration @tejensen23 www.biorxiv.org/content/10.1...

Check out our latest paper challenging the long-standing belief that insulin elicits a transient H₂O₂ production. New insights into skeletal muscle redox signaling and insulin action 🤩

“Exploring NADPH oxidases 2 and 4 in cardiac and skeletal muscle adaptations – A cross-tissue comparison” by @robertoandresmv.bsky.social, @musclebiology.bsky.social, @elbenhardt.bsky.social et al. (sorry if I do not find all of the #bluesky handles).

www.sciencedirect.com/science/arti...

3/17

The system is broken, also editors, in part, judge papers from the institutions and PI’s indexes in order to send papers for review

Even myoblasts enjoy mechanical stress. Keep your muscles strong 💪 #myoblue

Free radicals and antioxidants: appealing to magic

Our short paper argues that molecules cannot be classified as good or evil. Limited evidence supporting the consumption of antioxidants or superfoods and such interventions risk disrupting fundamental redox processes.

www.cell.com/trends/endoc...

Happy to join the #myoblue community. Aiming to share many many pictures of muscle fibers 😃