Nature Medicine
@natmed.nature.com
Nature Medicine is a research journal devoted to publishing the latest advances in translational and clinical research for scientists and physicians.
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⚡Our December issue is live! Check out our Year in Review for 2025 highlights and a what to look out for in 2026; also featuring news, opinioin & new research on #agingclocks, #liquidbiopsies, #Alzheimersdisease, #PCOS, #sepsis, & more.
Read it here: https://www.nature.com/nm/volumes/31/issues/12
Read it here: https://www.nature.com/nm/volumes/31/issues/12
Interpersonal conflict & excessive #socialmedia use are linked to increased levels of depression during political protests — but we must not lose sight of the wider contexts in which such protests take place. News & Views from Jon Roozenbeek, Ili Ma
https://www.nature.com/articles/s41591-025-04110-x
https://www.nature.com/articles/s41591-025-04110-x
Political protests, social media use and mental well-being - Nature Medicine
A large, longitudinal study shows that interpersonal conflict and excessive social media use are associated with increased levels of depression during political protests — but we should not lose sight of the wider contexts in which such protests take place.
www.nature.com
January 14, 2026 at 6:30 PM
Interpersonal conflict & excessive #socialmedia use are linked to increased levels of depression during political protests — but we must not lose sight of the wider contexts in which such protests take place. News & Views from Jon Roozenbeek, Ili Ma
https://www.nature.com/articles/s41591-025-04110-x
https://www.nature.com/articles/s41591-025-04110-x
🚨 Worried about infections? Angela Rasmussen explains how removing six vaccines to match Denmark’s schedule risks a measles comeback amid immune amnesia & fragile public health systems. Urgent plea: return to science‑led vaccine policy🧬#VaccinesWork https://ow.ly/8Jkl50XWi9P
January 13, 2026 at 5:49 PM
🚨 Worried about infections? Angela Rasmussen explains how removing six vaccines to match Denmark’s schedule risks a measles comeback amid immune amnesia & fragile public health systems. Urgent plea: return to science‑led vaccine policy🧬#VaccinesWork https://ow.ly/8Jkl50XWi9P
When is yogurt not yogurt?
Moran, Khandpur & Roberto in Nature Medicine propose defining ultra‑processed foods by what they are not to better regulate these products—avoiding loopholes that the food industry exploits.
Read more👉https://ow.ly/Wszx50XTkg4 (Also in STAT News!) #nutrition #foodpolicy
Moran, Khandpur & Roberto in Nature Medicine propose defining ultra‑processed foods by what they are not to better regulate these products—avoiding loopholes that the food industry exploits.
Read more👉https://ow.ly/Wszx50XTkg4 (Also in STAT News!) #nutrition #foodpolicy
Identifying ultra-processed foods for policy - Nature Medicine
Defining non-ultra-processed foods, rather than ultra-processed foods, would better protect the public’s health.
ow.ly
January 13, 2026 at 4:05 PM
When is yogurt not yogurt?
Moran, Khandpur & Roberto in Nature Medicine propose defining ultra‑processed foods by what they are not to better regulate these products—avoiding loopholes that the food industry exploits.
Read more👉https://ow.ly/Wszx50XTkg4 (Also in STAT News!) #nutrition #foodpolicy
Moran, Khandpur & Roberto in Nature Medicine propose defining ultra‑processed foods by what they are not to better regulate these products—avoiding loopholes that the food industry exploits.
Read more👉https://ow.ly/Wszx50XTkg4 (Also in STAT News!) #nutrition #foodpolicy
Including data from 1,047 patients across 19 inflammatory diseases, a new atlas presents a comprehensive model of inflammation in circulating immune cells.
https://www.nature.com/articles/s41591-025-04126-3
https://www.nature.com/articles/s41591-025-04126-3
Interpretable inflammation landscape of circulating immune cells - Nature Medicine
Including data from 1,047 patients across 19 inflammatory diseases, a new atlas presents a comprehensive model of inflammation in circulating immune cells.
www.nature.com
January 12, 2026 at 3:26 PM
Including data from 1,047 patients across 19 inflammatory diseases, a new atlas presents a comprehensive model of inflammation in circulating immune cells.
https://www.nature.com/articles/s41591-025-04126-3
https://www.nature.com/articles/s41591-025-04126-3
🛡️ Comment on “Lessons in public trust” by Heidi Larson (profheidilarson.bsky.social) & Alexander Toledo make a compelling case that strategies used to safeguard vaccine confidence are essential to restoring public faith in organ donation programs.
👉 Full Article: https://ow.ly/IXgn50XSpzQ
👉 Full Article: https://ow.ly/IXgn50XSpzQ
January 6, 2026 at 2:10 PM
🛡️ Comment on “Lessons in public trust” by Heidi Larson (profheidilarson.bsky.social) & Alexander Toledo make a compelling case that strategies used to safeguard vaccine confidence are essential to restoring public faith in organ donation programs.
👉 Full Article: https://ow.ly/IXgn50XSpzQ
👉 Full Article: https://ow.ly/IXgn50XSpzQ
📢 Don’t miss this!
“Eleven clinical trials that will shape medicine in 2026” — FREE to access in Nature Medicine.
See the editors' picks of next-gen vaccines, stem cell therapies and innovative cancer treatments to watch in 2026.
👉 https://ow.ly/ahfu50XLxka
“Eleven clinical trials that will shape medicine in 2026” — FREE to access in Nature Medicine.
See the editors' picks of next-gen vaccines, stem cell therapies and innovative cancer treatments to watch in 2026.
👉 https://ow.ly/ahfu50XLxka
Eleven clinical trials that will shape medicine in 2026 - Nature Medicine
Nature Medicine asks leading researchers to name their top clinical trial for 2026, from long-awaited vaccines for infectious diseases to new treatments for advanced cancers and long COVID.
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December 19, 2025 at 3:01 PM
📢 Don’t miss this!
“Eleven clinical trials that will shape medicine in 2026” — FREE to access in Nature Medicine.
See the editors' picks of next-gen vaccines, stem cell therapies and innovative cancer treatments to watch in 2026.
👉 https://ow.ly/ahfu50XLxka
“Eleven clinical trials that will shape medicine in 2026” — FREE to access in Nature Medicine.
See the editors' picks of next-gen vaccines, stem cell therapies and innovative cancer treatments to watch in 2026.
👉 https://ow.ly/ahfu50XLxka
In a year that has dealt many blows to biomedical research, many breakthroughs nevertheless continued to inspire us. Here is our selection of critical developments that moved medicine forward in 2025.
https://www.nature.com/articles/s41591-025-04098-4
https://www.nature.com/articles/s41591-025-04098-4
Notable advances 2025 - Nature Medicine
In a year that has dealt many blows to biomedical research, many breakthroughs nevertheless continued to inspire us. From regenerative medicine to reproductive technologies and everything in between — here is our selection of critical developments that moved medicine forward in 2025.
www.nature.com
December 18, 2025 at 2:02 PM
In a year that has dealt many blows to biomedical research, many breakthroughs nevertheless continued to inspire us. Here is our selection of critical developments that moved medicine forward in 2025.
https://www.nature.com/articles/s41591-025-04098-4
https://www.nature.com/articles/s41591-025-04098-4
⚡Our December issue is live! Check out our Year in Review for 2025 highlights and a what to look out for in 2026; also featuring news, opinioin & new research on #agingclocks, #liquidbiopsies, #Alzheimersdisease, #PCOS, #sepsis, & more.
Read it here: https://www.nature.com/nm/volumes/31/issues/12
Read it here: https://www.nature.com/nm/volumes/31/issues/12
December 18, 2025 at 12:53 PM
⚡Our December issue is live! Check out our Year in Review for 2025 highlights and a what to look out for in 2026; also featuring news, opinioin & new research on #agingclocks, #liquidbiopsies, #Alzheimersdisease, #PCOS, #sepsis, & more.
Read it here: https://www.nature.com/nm/volumes/31/issues/12
Read it here: https://www.nature.com/nm/volumes/31/issues/12
Our latest Review discusses #liquidbiopsy approaches and their clinical validity and utility, highlighting opportunities to support implementation in cancer care. From Valsamo Anagnostou, Victor Velculescu et al. @hopkinsmedicine.bsky.social
https://www.nature.com/articles/s41591-025-04093-9
https://www.nature.com/articles/s41591-025-04093-9
Liquid biopsies across the cancer care continuum - Nature Medicine
This Review summarizes current and emerging liquid biopsy methods, together with their clinical validity and utility, and highlights opportunities to support their implementation throughout the cancer care continuum.
www.nature.com
December 11, 2025 at 1:01 PM
Our latest Review discusses #liquidbiopsy approaches and their clinical validity and utility, highlighting opportunities to support implementation in cancer care. From Valsamo Anagnostou, Victor Velculescu et al. @hopkinsmedicine.bsky.social
https://www.nature.com/articles/s41591-025-04093-9
https://www.nature.com/articles/s41591-025-04093-9
Derived from millions of routine clinical records, a full‑lifecycle clock reveals insights into development & aging, enabling diagnostic & mechanistic insights
News & Views from Nathan Price and colleagues at The Buck Institute for Research on Aging
https://www.nature.com/articles/s41591-025-04095-7
News & Views from Nathan Price and colleagues at The Buck Institute for Research on Aging
https://www.nature.com/articles/s41591-025-04095-7
A lifespan clock tells the biology of time - Nature Medicine
A full‑lifecycle clock derived from millions of routine clinical records reveals that human development and aging form a continuous physiological trajectory, enabling early disease detection and mechanistic insights for preventive and precision health.
www.nature.com
December 10, 2025 at 12:30 PM
Derived from millions of routine clinical records, a full‑lifecycle clock reveals insights into development & aging, enabling diagnostic & mechanistic insights
News & Views from Nathan Price and colleagues at The Buck Institute for Research on Aging
https://www.nature.com/articles/s41591-025-04095-7
News & Views from Nathan Price and colleagues at The Buck Institute for Research on Aging
https://www.nature.com/articles/s41591-025-04095-7
As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance. https://www.nature.com/articles/s41591-025-04044-4
Endotyping-informed therapy for patients with chest pain and no obstructive coronary artery disease: a randomized trial - Nature Medicine
As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance.
www.nature.com
December 5, 2025 at 7:30 PM
As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance. https://www.nature.com/articles/s41591-025-04044-4
A phase 1/2 and a phase 3 trials testing an AAV-FIX Padua gene therapy in patients with hemophilia B in China show that the treatment was well tolerated and effective in reducing annualized bleeding rate. https://www.nature.com/articles/s41591-025-04012-y
December 5, 2025 at 12:00 PM
A phase 1/2 and a phase 3 trials testing an AAV-FIX Padua gene therapy in patients with hemophilia B in China show that the treatment was well tolerated and effective in reducing annualized bleeding rate. https://www.nature.com/articles/s41591-025-04012-y
A new study provides the first evidence in humans that tirzepatide modulates brain electrophysiology, with changes in low-frequency accumbens power linked to food preoccupation.
https://www.nature.com/articles/s41591-025-04035-5
https://www.nature.com/articles/s41591-025-04035-5
December 2, 2025 at 4:00 PM
A new study provides the first evidence in humans that tirzepatide modulates brain electrophysiology, with changes in low-frequency accumbens power linked to food preoccupation.
https://www.nature.com/articles/s41591-025-04035-5
https://www.nature.com/articles/s41591-025-04035-5
How can we measure the value of #genomics in #healthcare? How can #HTA, #implementation & data management be adapted to suit the rapidly evolving nature of genomics? For insights, read the Review from Zornitza Stark, Ilias Goranitis & colleagues.
https://www.nature.com/articles/s41591-025-04061-3
https://www.nature.com/articles/s41591-025-04061-3
Determining the value of genomics in healthcare - Nature Medicine
Assessing the value of genomics is key to informing evidence-based policies; this Review outlines how current approaches to health technology assessment, implementation and data management can be adapted to suit the rapidly evolving technology and evidence base.
www.nature.com
December 2, 2025 at 12:30 PM
How can we measure the value of #genomics in #healthcare? How can #HTA, #implementation & data management be adapted to suit the rapidly evolving nature of genomics? For insights, read the Review from Zornitza Stark, Ilias Goranitis & colleagues.
https://www.nature.com/articles/s41591-025-04061-3
https://www.nature.com/articles/s41591-025-04061-3
In a phase 1 trial, treatment of fibrolamellar hepatocellular carcinoma with a therapeutic peptide vaccine targeting the DNAJB1::PRKACA fusion, together with nivolumab and ipilimumab, was safe and led to encouraging preliminary clinical responses. https://www.nature.com/articles/s41591-025-03995-y
December 1, 2025 at 1:00 PM
In a phase 1 trial, treatment of fibrolamellar hepatocellular carcinoma with a therapeutic peptide vaccine targeting the DNAJB1::PRKACA fusion, together with nivolumab and ipilimumab, was safe and led to encouraging preliminary clinical responses. https://www.nature.com/articles/s41591-025-03995-y
A combination of high resolution spatial imaging, spatial proteomics and transcriptional data reveals sparse and heterogeneous bacterial signals in gliomas and brain metastases. @gmorad.bsky.social https://www.nature.com/articles/s41591-025-03957-4
November 28, 2025 at 3:00 PM
A combination of high resolution spatial imaging, spatial proteomics and transcriptional data reveals sparse and heterogeneous bacterial signals in gliomas and brain metastases. @gmorad.bsky.social https://www.nature.com/articles/s41591-025-03957-4
In a phase 1 trial, treatment of fibrolamellar hepatocellular carcinoma with a therapeutic peptide vaccine targeting the DNAJB1::PRKACA fusion, together with nivolumab and ipilimumab, was safe and led to encouraging preliminary clinical responses. https://www.nature.com/articles/s41591-025-03995-y
November 26, 2025 at 1:01 PM
In a phase 1 trial, treatment of fibrolamellar hepatocellular carcinoma with a therapeutic peptide vaccine targeting the DNAJB1::PRKACA fusion, together with nivolumab and ipilimumab, was safe and led to encouraging preliminary clinical responses. https://www.nature.com/articles/s41591-025-03995-y
As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance. https://www.nature.com/articles/s41591-025-04044-4
Endotyping-informed therapy for patients with chest pain and no obstructive coronary artery disease: a randomized trial - Nature Medicine
As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance.
www.nature.com
November 25, 2025 at 7:30 PM
As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance. https://www.nature.com/articles/s41591-025-04044-4
A phase 1/2 and a phase 3 trials testing an AAV-FIX Padua gene therapy in patients with hemophilia B in China show that the treatment was well tolerated and effective in reducing annualized bleeding rate. https://www.nature.com/articles/s41591-025-04012-y
November 25, 2025 at 6:20 PM
A phase 1/2 and a phase 3 trials testing an AAV-FIX Padua gene therapy in patients with hemophilia B in China show that the treatment was well tolerated and effective in reducing annualized bleeding rate. https://www.nature.com/articles/s41591-025-04012-y
A new study provides the first evidence in humans that tirzepatide modulates brain electrophysiology, with changes in low-frequency accumbens power linked to food preoccupation.
https://www.nature.com/articles/s41591-025-04035-5
https://www.nature.com/articles/s41591-025-04035-5
November 25, 2025 at 4:02 PM
A new study provides the first evidence in humans that tirzepatide modulates brain electrophysiology, with changes in low-frequency accumbens power linked to food preoccupation.
https://www.nature.com/articles/s41591-025-04035-5
https://www.nature.com/articles/s41591-025-04035-5
A landmark clinical trial of gene therapy infusion for hemophilia B revealed surprising findings—reshaping the future of genetic medicine.
Read the full Turning Point essay in Nature Medicine: https://ow.ly/RVST50XvVs0
#GeneTherapy #HemophiliaB #NatureMedicine
Read the full Turning Point essay in Nature Medicine: https://ow.ly/RVST50XvVs0
#GeneTherapy #HemophiliaB #NatureMedicine
Turning genes into medicines - Nature Medicine
The first clinical trial of a gene therapy infusion for hemophilia B revealed unexpected findings.
ow.ly
November 21, 2025 at 5:17 PM
A landmark clinical trial of gene therapy infusion for hemophilia B revealed surprising findings—reshaping the future of genetic medicine.
Read the full Turning Point essay in Nature Medicine: https://ow.ly/RVST50XvVs0
#GeneTherapy #HemophiliaB #NatureMedicine
Read the full Turning Point essay in Nature Medicine: https://ow.ly/RVST50XvVs0
#GeneTherapy #HemophiliaB #NatureMedicine
Women, children & adolescents bear the brunt of climate impacts — from preterm births to malnutrition.
In Nature Medicine, Rajat Khosla, Helen Clark & co-authors outline actionable strategies for climate resilience & health equity.
Free to access 👉 www.nature.com/articles/d41...
#COP30 #HealthForAll
In Nature Medicine, Rajat Khosla, Helen Clark & co-authors outline actionable strategies for climate resilience & health equity.
Free to access 👉 www.nature.com/articles/d41...
#COP30 #HealthForAll
November 20, 2025 at 5:27 PM
Women, children & adolescents bear the brunt of climate impacts — from preterm births to malnutrition.
In Nature Medicine, Rajat Khosla, Helen Clark & co-authors outline actionable strategies for climate resilience & health equity.
Free to access 👉 www.nature.com/articles/d41...
#COP30 #HealthForAll
In Nature Medicine, Rajat Khosla, Helen Clark & co-authors outline actionable strategies for climate resilience & health equity.
Free to access 👉 www.nature.com/articles/d41...
#COP30 #HealthForAll
⚡Our November issue is out! Featuring trials of #CARTcells for #LUPUS, an #ADC for #lungcancer, cardiac #genetherapy, an #ebola #vaccine, discovery of microbial elements in #braintumors, #liquidbiopsies, #newbornscreening, News, Reviews, & more.
https://www.nature.com/nm/volumes/31/issues/11
https://www.nature.com/nm/volumes/31/issues/11
November 19, 2025 at 4:33 PM
⚡Our November issue is out! Featuring trials of #CARTcells for #LUPUS, an #ADC for #lungcancer, cardiac #genetherapy, an #ebola #vaccine, discovery of microbial elements in #braintumors, #liquidbiopsies, #newbornscreening, News, Reviews, & more.
https://www.nature.com/nm/volumes/31/issues/11
https://www.nature.com/nm/volumes/31/issues/11
A combination of high resolution spatial imaging, spatial proteomics and transcriptional data reveals sparse and heterogeneous bacterial signals in gliomas and brain metastases. @gmorad.bsky.social https://www.nature.com/articles/s41591-025-03957-4
November 19, 2025 at 1:15 PM
A combination of high resolution spatial imaging, spatial proteomics and transcriptional data reveals sparse and heterogeneous bacterial signals in gliomas and brain metastases. @gmorad.bsky.social https://www.nature.com/articles/s41591-025-03957-4
Pretrained using 335,645 whole-slide images, a foundation model is developed to provide representations for slide- and patient-level tasks. It is capable of performing clinical tasks even in data-scarce scenarios, without further fine-tuning. https://www.nature.com/articles/s41591-025-03982-3
November 18, 2025 at 3:15 PM
Pretrained using 335,645 whole-slide images, a foundation model is developed to provide representations for slide- and patient-level tasks. It is capable of performing clinical tasks even in data-scarce scenarios, without further fine-tuning. https://www.nature.com/articles/s41591-025-03982-3