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Nature Reviews Methods Primers
@natrevmethodsprimers.nature.com
Nature Reviews Methods Primers publishes Primers - introductory reviews on methods and techniques across the life and physical sciences. https://www.nature.com/nrmp/
Day 6️⃣ of the NRMP 5th Anniversary Highlights 🧁

Continuing to address the advancement of #AI in methods, this Q&A discusses concerns such as quality, transparency, and reproducibility in AI-driven research.
www.nature.com/articles/s43...
Promoting open and transparent research in an AI-driven world - Nature Reviews Methods Primers
Artificial intelligence is increasingly used for data analysis, literature synthesis and experimental design, posing a challenge to open research. Here, David Moher of the Ottawa Hospital Research Ins...
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January 16, 2026 at 2:50 PM
Day 5️⃣ of the NRMP 5th Anniversary Highlights 🧁

What's rugged, portable, and analytically precise? A Raman spectrometer, of course!

This comment discusses how Raman spectroscopy can be adapted for use in extreme environments, like space. 🪐
www.nature.com/articles/s43...
Using Raman spectrometers developed for space exploration in other extreme environments - Nature Reviews Methods Primers
Optimizing Raman spectrometer designs for use in extreme environments can enable acquisition of critical information that may not be accessible in situ by humans. Technology advancements currently bei...
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January 15, 2026 at 5:32 PM
Check out answers to these questions, and more, in this Q&A with Rainer Bromme: www.nature.com/articles/s43...
Client Challenge
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January 14, 2026 at 3:47 PM
Day 4️⃣ of the NRMP 5th Anniversary Highlights 🧁

With the rising influence of #AI, how should researchers best communicate their findings and what are the best avenues for the general public to read these results?
January 14, 2026 at 3:47 PM
Day3️⃣ of the NRMP 5th Anniversary Highlights🧁

From @audreyalejandro.bsky.social at @lsemethodology.bsky.social comes a topic that everyone can reflect on, #reflexivity. Learn more about your bias and applying these realizations to your research 👇 www.nature.com/articles/s43...
Client Challenge
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January 13, 2026 at 5:48 PM
This Comment draws on discussions from the National Heart, Lung, and Blood Institute Workshop on Digital Twins in Heart Lung and Sleep Research held in September 2025. 🫀🫁🩸🛌
January 12, 2026 at 4:09 PM
Day2️⃣ of the NRMP 5th Anniversary Highlights 🧁

@clancyatheart.bsky.social and @masi-lab.bsky.social discuss the emerging role of digital twins, combined with AI, for biomedical research that can inform preclinical decisions.

www.nature.com/articles/s43...
Client Challenge
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January 12, 2026 at 4:09 PM
Day 1️⃣ of the NRMP 5th Anniversary Highlights 🧁

Joshua Patterson provides tips for designing undergraduate research projects. 🎓🏫 When undergraduates have limited time and expertise, how do you craft a project that will keep them engaged and successful? www.nature.com/articles/s43...
Client Challenge
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January 9, 2026 at 6:34 PM
Reposted by Nature Reviews Methods Primers
🔭 What’s the future of reflexivity & how do we put it into practice? New article in @natrevmethodsprimers.nature.com
I argue for three priorities 1) evaluation criteria 2) studying reflexivity as a socio-cognitive phenomenon 3) adapting it across research traditions
OA: rdcu.be/eX79L
January 8, 2026 at 12:22 PM
To kick things off, check out this Editorial 👇 that reflects on the past 5 years of NRMP and discusses the increasing role of AI in method development.
www.nature.com/articles/s43...
Client Challenge
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January 8, 2026 at 4:11 PM
This month, we are celebrating 5 years of Nature Reviews Methods Primers with a variety of Comments and Q&As that address recent advancements in methods!
January 8, 2026 at 4:11 PM
Thanks to @cecilesauvanet.bsky.social, @doritsb.bsky.social, and the rest of the team!
December 11, 2025 at 3:54 PM
The associated #PrimeView features the sample preparation necessary for achieving high-quality #cryo-ET images 👨‍🔬👩‍🔬🖼️
www.nature.com/articles/s43...
Correlative cryogenic light and electron tomography of eukaryotic cells - Nature Reviews Methods Primers
This PrimeView outlines the key sample-preparation workflows involved in analysing eukaryotic cells with cryogenic electron tomography (cryo-ET).
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December 11, 2025 at 3:54 PM
This week, check out a new #Primer on #cryogenic electron tomography (cryo-ET) used for visualizing 3D structures of cells with sub-nanometer resolution. 🔬🧫
www.nature.com/articles/s43...
Correlative cryogenic light and electron tomography of eukaryotic cells - Nature Reviews Methods Primers
Cryogenic electron tomography provides unparalleled insights into cell biology and disease. When combined with light microscopy, it enables precise localization of regions of interest and direct corre...
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December 11, 2025 at 3:54 PM
A huge thanks to our author team, including @irssubc.bsky.social @forestry.ubc.ca @lwiniwar.bsky.social
November 27, 2025 at 10:30 AM
The #PrimeView highlights the various applications of lidar in the environment, from snow depth mapping to riverbed geomorphology. Check it out here:
www.nature.com/articles/s43586-025-00452-5
Light detection and ranging of natural systems - Nature Reviews Methods Primers
This PrimeView highlights the various applications of lidar in the environment, from snow depth mapping to riverbed geomorphology.
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November 27, 2025 at 10:30 AM
Explore the potential of #lidar in our latest #Primer, an active remote sensing technology that can consistently measure distances by emitting light from a laser source and recording the signal reflected from the target. www.nature.com/articles/s43586-025-00446-3
Light detection and ranging of natural systems - Nature Reviews Methods Primers
Light detection and ranging (lidar) is an active remote sensing technology that produces foundational geospatial datasets across natural systems. This Primer introduces core lidar technological compon...
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November 27, 2025 at 10:30 AM
A huge thanks to our diverse author team, including @durrant-group.bsky.social, @ifanstephens.bsky.social, and many others!
November 20, 2025 at 3:30 PM
The #PrimeView highlights the spectral results obtained from SEC, such as cyclic voltammetry SEC, square-wave voltammetry SEC, and potential decay SEC. 💡📑 Check it out here: www.nature.com/articles/s43...
Operando ultraviolet–visible optical spectroelectrochemistry of surfaces - Nature Reviews Methods Primers
This PrimeView highlights the variety of information that can be obtained using spectroelectrochemistry depending on the mode of operation.
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November 20, 2025 at 3:30 PM
Our newest #Primer is on #spectroelectrochemistry (SEC), a method for studying redox-active interfaces in a UV-Vis spectral window. With this technique, redox stoichiometries and kinetics can be determined and analyzed. 🌈🔋https://www.nature.com/articles/s43586-025-00445-4
November 20, 2025 at 3:30 PM
The related #PrimeView highlights the experimental setup of frontal polymerization where the ignition of an initiator generates a reactive intermediate for polymerization. 🔥🧪
www.nature.com/articles/s43...
Frontal polymerization for rapid low-energy synthesis - Nature Reviews Methods Primers
In frontal polymerization, a self-sustaining reaction is driven by the heat generated by the reactive front. This PrimeView features the experimental process of frontal polymerization, including a var...
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November 13, 2025 at 4:18 PM
This week #Primer is on frontal #polymerization, a self-sustaining, energy-efficient method for polymerization! This technique is used in radical-induced cationic frontal polymerization and frontal ring-opening metathesis polymerization. Check it out here: www.nature.com/articles/s43...
Frontal polymerization for rapid low-energy synthesis - Nature Reviews Methods Primers
Frontal polymerization is a self-sustaining, energy-efficient technique for rapidly converting monomers into polymers. This Primer explores frontal polymerization mechanisms, experimental set-up, appl...
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November 13, 2025 at 4:18 PM
Thanks to our diverse author team from @diamondlightsource.bsky.social, @sheffielduni.bsky.social, @dukeengineering.bsky.social, and beyond!
October 30, 2025 at 2:25 PM
The associated #PrimeView features the variety of applications of #ptychography, such as inspection in industrial manufacturing, material characterization, and live cell imaging.📱⚛️🧑‍🔬
www.nature.com/articles/s43...
Ptychography at all wavelengths - Nature Reviews Methods Primers
This PrimeView outlines the use of ptychography to obtain high-resolution images for applications across the life sciences, materials sciences and industry.
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October 30, 2025 at 2:25 PM