Nature Synthesis
@natsynth.nature.com
A synthesis-oriented chemistry & materials science journal from
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@natureportfolio.nature.com. Posts by the editors @peterseavill.bsky.social @alexrgroves.bsky.social @jetsinglee.bsky.social
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January 13, 2026 at 4:58 PM
Now online:
Article by Tao Xiong & co-workers
Catalytic asymmetric hydroalkylation of 1,1-dialkyl-substituted alkenes with unactivated alkyl electrophiles
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Article by Tao Xiong & co-workers
Catalytic asymmetric hydroalkylation of 1,1-dialkyl-substituted alkenes with unactivated alkyl electrophiles
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January 13, 2026 at 12:57 PM
Now online:
Article by Tao Xiong & co-workers
Catalytic asymmetric hydroalkylation of 1,1-dialkyl-substituted alkenes with unactivated alkyl electrophiles
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Article by Tao Xiong & co-workers
Catalytic asymmetric hydroalkylation of 1,1-dialkyl-substituted alkenes with unactivated alkyl electrophiles
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Now online:
Article by Zhenxing Wang, Feng Wang, Qingdao Zeng, Zhenpeng Hu, Jun He & co-workers
Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering
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Article by Zhenxing Wang, Feng Wang, Qingdao Zeng, Zhenpeng Hu, Jun He & co-workers
Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering
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Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering - Nature Synthesis
Using a molecular engineering approach, wafer-scale uniaxially oriented Te nanowire thin films are synthesized with excellent controllability and uniformity. The anchor-rope structural molecules form ...
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January 6, 2026 at 11:55 AM
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Article by Zhenxing Wang, Feng Wang, Qingdao Zeng, Zhenpeng Hu, Jun He & co-workers
Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering
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Article by Zhenxing Wang, Feng Wang, Qingdao Zeng, Zhenpeng Hu, Jun He & co-workers
Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering
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Now online:
Article by Kang Cai, Dong-Sheng Guo, Jonathan L. Sessler, Chunju Li & co-workers
Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes
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Article by Kang Cai, Dong-Sheng Guo, Jonathan L. Sessler, Chunju Li & co-workers
Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes
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Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes - Nature Synthesis
Intramolecular coupling of extended biphen[n]arenes is developed to yield cycloparaphenylenes (CPPs). The modular nature of biphen[n]arenes makes it possible to customize CPP structures, which permits...
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January 6, 2026 at 11:51 AM
Now online:
Article by Kang Cai, Dong-Sheng Guo, Jonathan L. Sessler, Chunju Li & co-workers
Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes
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Article by Kang Cai, Dong-Sheng Guo, Jonathan L. Sessler, Chunju Li & co-workers
Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes
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Now online and open access:
Article by Hai I. Wang, Minghao Yu, Xinliang Feng & co-workers
Triphasic synthesis of MXenes with uniform and controlled halogen terminations
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Article by Hai I. Wang, Minghao Yu, Xinliang Feng & co-workers
Triphasic synthesis of MXenes with uniform and controlled halogen terminations
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Triphasic synthesis of MXenes with uniform and controlled halogen terminations - Nature Synthesis
A gas–liquid–solid triphasic etching strategy is demonstrated to obtain MXenes with uniform and tunable halogen terminations. The resulting MXenes have highly ordered structures, enhanced charge trans...
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January 6, 2026 at 11:49 AM
Now online and open access:
Article by Hai I. Wang, Minghao Yu, Xinliang Feng & co-workers
Triphasic synthesis of MXenes with uniform and controlled halogen terminations
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Article by Hai I. Wang, Minghao Yu, Xinliang Feng & co-workers
Triphasic synthesis of MXenes with uniform and controlled halogen terminations
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Research Highlight now online:
A terminal germanium oxido dianion by Bei Zhang
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Highlighting the @jacs.acspublications.org article by Valentin D. Hannibal & Lutz Greb
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A terminal germanium oxido dianion by Bei Zhang
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Highlighting the @jacs.acspublications.org article by Valentin D. Hannibal & Lutz Greb
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A terminal germanium oxido dianion - Nature Synthesis
Nature Synthesis - A terminal germanium oxido dianion
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January 5, 2026 at 12:51 PM
Research Highlight now online:
A terminal germanium oxido dianion by Bei Zhang
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Highlighting the @jacs.acspublications.org article by Valentin D. Hannibal & Lutz Greb
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A terminal germanium oxido dianion by Bei Zhang
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Highlighting the @jacs.acspublications.org article by Valentin D. Hannibal & Lutz Greb
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Research Highlight now online:
Ammonia synthesis over AuRu alloys by @alexrgroves.bsky.social
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Highlighting the @natenergy.nature.com Article by Lin Yuan, Junwei Lucas Bao, Jennifer A. Dionne & co-workers
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Ammonia synthesis over AuRu alloys by @alexrgroves.bsky.social
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Highlighting the @natenergy.nature.com Article by Lin Yuan, Junwei Lucas Bao, Jennifer A. Dionne & co-workers
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Ammonia synthesis over AuRu alloys - Nature Synthesis
Nature Synthesis - Ammonia synthesis over AuRu alloys
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January 5, 2026 at 12:49 PM
Research Highlight now online:
Ammonia synthesis over AuRu alloys by @alexrgroves.bsky.social
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Highlighting the @natenergy.nature.com Article by Lin Yuan, Junwei Lucas Bao, Jennifer A. Dionne & co-workers
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Ammonia synthesis over AuRu alloys by @alexrgroves.bsky.social
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Highlighting the @natenergy.nature.com Article by Lin Yuan, Junwei Lucas Bao, Jennifer A. Dionne & co-workers
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Now online:
News & Views on the Articles:
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And
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meta-Selective radical halogenation of pyridines by Nirmala Mohanta & Jacquelyne A. Read
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News & Views on the Articles:
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And
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meta-Selective radical halogenation of pyridines by Nirmala Mohanta & Jacquelyne A. Read
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meta-Selective radical halogenation of pyridines - Nature Synthesis
Radical processes can be leveraged to impart meta selectivity in pyridine functionalization, offering a valuable approach for the late-stage functionalization of bioactive molecules.
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January 5, 2026 at 12:44 PM
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News & Views on the Articles:
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And
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meta-Selective radical halogenation of pyridines by Nirmala Mohanta & Jacquelyne A. Read
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News & Views on the Articles:
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And
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meta-Selective radical halogenation of pyridines by Nirmala Mohanta & Jacquelyne A. Read
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Now online:
News & Views on the Article by Aoni Xu, Sung-Fu Hung & co-workers
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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts by Karl Adrian Gandionco, Zhiyuan Zhang & Jongwoo Lim
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News & Views on the Article by Aoni Xu, Sung-Fu Hung & co-workers
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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts by Karl Adrian Gandionco, Zhiyuan Zhang & Jongwoo Lim
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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts - Nature Synthesis
The strategic placement of sulfur within a nickel porphyrin complex coupled with copper facilitates efficient electrochemical CO2 reduction to ethylene and ethanol.
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January 5, 2026 at 12:35 PM
Now online:
News & Views on the Article by Aoni Xu, Sung-Fu Hung & co-workers
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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts by Karl Adrian Gandionco, Zhiyuan Zhang & Jongwoo Lim
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News & Views on the Article by Aoni Xu, Sung-Fu Hung & co-workers
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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts by Karl Adrian Gandionco, Zhiyuan Zhang & Jongwoo Lim
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Now online:
Article by Li-Ping Xu, Hao Wei & co-workers
Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles
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Article by Li-Ping Xu, Hao Wei & co-workers
Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles
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Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles - Nature Synthesis
A skeletal editing strategy for the direct conversion of oxazoles and isoxazoles into thiazoles and isothiazoles is described. These one-step transformations may be beneficial for drug development pro...
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January 5, 2026 at 12:29 PM
Now online:
Article by Li-Ping Xu, Hao Wei & co-workers
Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles
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Article by Li-Ping Xu, Hao Wei & co-workers
Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles
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Now online and open access:
Article by Benjamin List & co-workers
Catalytic asymmetric activation of bicyclobutanes
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Article by Benjamin List & co-workers
Catalytic asymmetric activation of bicyclobutanes
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Catalytic asymmetric activation of bicyclobutanes - Nature Synthesis
The precise manipulation of unfunctionalized hydrocarbons remains a fundamental challenge in chemical synthesis and catalysis. Here an organocatalytic asymmetric hydroxylation of bicyclobutanes with a...
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January 5, 2026 at 12:27 PM
Now online and open access:
Article by Benjamin List & co-workers
Catalytic asymmetric activation of bicyclobutanes
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Article by Benjamin List & co-workers
Catalytic asymmetric activation of bicyclobutanes
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Now online:
Article by Jie Yang, Hengxu Li, Qiong Wang & Qiang Liu
Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling
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Article by Jie Yang, Hengxu Li, Qiong Wang & Qiang Liu
Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling
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Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling - Nature Synthesis
An electrochemical cobalt-catalysed reductive coupling reaction between alkynes and cyclobutenes enables diastereodivergent cyclobutane synthesis. By modulating the steric and electronic properties of...
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January 5, 2026 at 12:25 PM
Now online:
Article by Jie Yang, Hengxu Li, Qiong Wang & Qiang Liu
Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling
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Article by Jie Yang, Hengxu Li, Qiong Wang & Qiang Liu
Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling
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Now online:
Article by Peidong Yang, Hailiang Wang & co-workers
Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide
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Article by Peidong Yang, Hailiang Wang & co-workers
Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide
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Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide - Nature Synthesis
The sustainable synthesis of carbohydrates from CO2 is challenging due to the complexity of controlled CO2 reduction. Here a two-step method for the sustainable synthesis of C5+ carbohydrates is repor...
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January 2, 2026 at 4:16 PM
Now online:
Article by Peidong Yang, Hailiang Wang & co-workers
Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide
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Article by Peidong Yang, Hailiang Wang & co-workers
Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide
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Now online:
Article by Rui Tan, Shiyong Liu, Zhengbiao Zhang & co-workers
Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins
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Article by Rui Tan, Shiyong Liu, Zhengbiao Zhang & co-workers
Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins
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Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins - Nature Synthesis
The precision synthesis of uniform oligoethylenes with chain lengths of up to 576 carbon atoms is achieved via an iterative growth approach based on the Julia–Kocienski reaction. The oligoethylenes ar...
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January 2, 2026 at 4:14 PM
Now online:
Article by Rui Tan, Shiyong Liu, Zhengbiao Zhang & co-workers
Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins
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Article by Rui Tan, Shiyong Liu, Zhengbiao Zhang & co-workers
Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins
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Now online:
Article by Yu Zhao, Ming Joo Koh & co-workers
Divergent synthesis of N heterocycles from carbocycles enabled by electrochemical nitrogen atom insertion
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Article by Yu Zhao, Ming Joo Koh & co-workers
Divergent synthesis of N heterocycles from carbocycles enabled by electrochemical nitrogen atom insertion
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Divergent synthesis of N heterocycles from carbocycles enabled by electrochemical nitrogen atom insertion - Nature Synthesis
A divergent electrochemical nitrogen atom insertion into saturated carbocycles is reported, enabling selective access to either functionalized quinolines or N-alkylated saturated N heterocycles. This ...
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December 18, 2025 at 1:46 PM
Now online:
Article by Yu Zhao, Ming Joo Koh & co-workers
Divergent synthesis of N heterocycles from carbocycles enabled by electrochemical nitrogen atom insertion
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Article by Yu Zhao, Ming Joo Koh & co-workers
Divergent synthesis of N heterocycles from carbocycles enabled by electrochemical nitrogen atom insertion
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Reposted by Nature Synthesis
I’m here at #Pacifichem2025, looking forward to meeting peeps and talking about all things synthetic @natsynth.nature.com
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December 15, 2025 at 9:17 PM
I’m here at #Pacifichem2025, looking forward to meeting peeps and talking about all things synthetic @natsynth.nature.com
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Now online and open access:
Article by Pavel K. Mykhailiuk, Peng Liu, K. Barry Sharpless, Keary M. Engle & co-workers
Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes
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Article by Pavel K. Mykhailiuk, Peng Liu, K. Barry Sharpless, Keary M. Engle & co-workers
Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes
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Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes - Nature Synthesis
The ambiphilic reactivity of alkyl sulfonyl fluorides in stereoselective cyclopropanation under Pd(II) catalysis is reported. The method provides convenient access to cis-disubstituted cyclopropanes t...
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December 16, 2025 at 1:51 PM
Now online and open access:
Article by Pavel K. Mykhailiuk, Peng Liu, K. Barry Sharpless, Keary M. Engle & co-workers
Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes
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Article by Pavel K. Mykhailiuk, Peng Liu, K. Barry Sharpless, Keary M. Engle & co-workers
Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes
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December 15, 2025 at 10:37 AM
Research Highlight now online:
Heck-type reactions with bismuth photocatalysts by Eric Piechota
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Highlighting the Nature Catalysis Article by Josep Cornella & co-workers
Heck-type reactions with bismuth photocatalysts by Eric Piechota
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Highlighting the Nature Catalysis Article by Josep Cornella & co-workers
Heck-type reactions with bismuth photocatalysts - Nature Synthesis
Nature Synthesis - Heck-type reactions with bismuth photocatalysts
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December 15, 2025 at 10:34 AM
Research Highlight now online:
Heck-type reactions with bismuth photocatalysts by Eric Piechota
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Highlighting the Nature Catalysis Article by Josep Cornella & co-workers
Heck-type reactions with bismuth photocatalysts by Eric Piechota
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Highlighting the Nature Catalysis Article by Josep Cornella & co-workers
Now online:
Article by Jianwei Nai, Lin Guo, Hua Wang & co-workers
Scalable ultrathin sodium metal anodes
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Article by Jianwei Nai, Lin Guo, Hua Wang & co-workers
Scalable ultrathin sodium metal anodes
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Scalable ultrathin sodium metal anodes - Nature Synthesis
Sodium metal is of interest for high-energy-density batteries, but the lack of large-area ultrathin sodium metal foils hinders research. Here a metre-length, ultrathin (≤50 μm), mechanically strengthe...
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December 15, 2025 at 10:29 AM
Now online:
Article by Jianwei Nai, Lin Guo, Hua Wang & co-workers
Scalable ultrathin sodium metal anodes
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Article by Jianwei Nai, Lin Guo, Hua Wang & co-workers
Scalable ultrathin sodium metal anodes
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Now online and open access:
Article by Roly J. Armstrong, Erli Lu, Koji Kubota, Hajime Ito & co-workers
Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides
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Article by Roly J. Armstrong, Erli Lu, Koji Kubota, Hajime Ito & co-workers
Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides
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Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides - Nature Synthesis
A mechanochemical protocol for the direct synthesis of organosodium compounds is developed using cheap and shelf-stable sodium lumps and readily available organic halides under bulk, solvent-free cond...
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December 15, 2025 at 10:25 AM
Now online and open access:
Article by Roly J. Armstrong, Erli Lu, Koji Kubota, Hajime Ito & co-workers
Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides
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Article by Roly J. Armstrong, Erli Lu, Koji Kubota, Hajime Ito & co-workers
Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides
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Now online:
Review article by Weihua Guo, Zihao Li, Libei Huang, Ma Qian, James M. Tour & Ruquan Ye
Laser-assisted materials engineering at the atomic and nanoscales
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Review article by Weihua Guo, Zihao Li, Libei Huang, Ma Qian, James M. Tour & Ruquan Ye
Laser-assisted materials engineering at the atomic and nanoscales
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Laser-assisted materials engineering at the atomic and nanoscales - Nature Synthesis
Laser technology offers high energy, precise spatial resolution and seamless automation for materials synthesis and device fabrication. This Review highlights laser-assisted materials engineering at t...
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December 5, 2025 at 3:42 PM
Now online:
Review article by Weihua Guo, Zihao Li, Libei Huang, Ma Qian, James M. Tour & Ruquan Ye
Laser-assisted materials engineering at the atomic and nanoscales
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Review article by Weihua Guo, Zihao Li, Libei Huang, Ma Qian, James M. Tour & Ruquan Ye
Laser-assisted materials engineering at the atomic and nanoscales
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Now online:
Article by Min Ye, Xue Qiao, Menghao Cai & co-workers
Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast
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Article by Min Ye, Xue Qiao, Menghao Cai & co-workers
Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast
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Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast - Nature Synthesis
Microbial biosynthesis is a promising alternative to plant extraction to obtain post-modified flavonoids, but current de novo biosynthesis is limited to milligrams per litre. Now the production of pla...
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December 5, 2025 at 3:37 PM
Now online:
Article by Min Ye, Xue Qiao, Menghao Cai & co-workers
Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast
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Article by Min Ye, Xue Qiao, Menghao Cai & co-workers
Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast
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Article by Dmitri V. Talapin & co-workers
Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes
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Article by Dmitri V. Talapin & co-workers
Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes
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Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes - Nature Synthesis
Ti-, Zr- and Nb-based MXenes with Cl, Br or mixed terminations can be synthesized by a bottom-up, atom-economic route directly from metals and molecular organohalides. The reactivity of organohalide p...
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December 3, 2025 at 5:16 PM
Now online:
Article by Dmitri V. Talapin & co-workers
Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes
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Article by Dmitri V. Talapin & co-workers
Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes
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Now online:
News & Views by @jetsinglee.bsky.social to mark the 2025 Nobel Prize in Chemistry
Medal for metal–organic frameworks
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News & Views by @jetsinglee.bsky.social to mark the 2025 Nobel Prize in Chemistry
Medal for metal–organic frameworks
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Medal for metal–organic frameworks - Nature Synthesis
Building space into solids is the focus of the 2025 Nobel Prize in Chemistry, which has been awarded to Susumu Kitagawa (Kyoto University), Richard Robson (University of Melbourne) and Omar M. Yaghi (...
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December 1, 2025 at 3:26 PM
Now online:
News & Views by @jetsinglee.bsky.social to mark the 2025 Nobel Prize in Chemistry
Medal for metal–organic frameworks
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News & Views by @jetsinglee.bsky.social to mark the 2025 Nobel Prize in Chemistry
Medal for metal–organic frameworks
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