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NC3Rs @nc3rs.bsky.social · 6d

Recordings available: nc3rs.org.uk/crackit/tech...

Watch presentations from six model developers to learn more about their technologies and explore new partnerships to access 3Rs approaches for your oncology research.

NC3Rs @nc3rs.bsky.social · Sep 5

Are you interested in the latest 3Rs technologies in oncology research? Join us at our next Technology Partn3Ring webinar for opportunities to collaborate and access new 3Rs models.
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...

Cartoon icon of a cancer cells surrounded by icons of lightbulbs, shaking hands and silhouettes.

NC3Rs @nc3rs.bsky.social · 8d

We were delighted to welcome 12 BBSRC-funded PhD students to our annual summer school this year alongside NC3Rs-funded students. Our training for early career researchers focuses on their role as ambassadors for the 3Rs throughout their PhD and beyond.

💡 Read more: nc3rs.org.uk/news/trainin...

PhD students in an experimental design workshop at the NC3Rs-BBSRC summer school.

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NC3Rs @nc3rs.bsky.social · 15d

The Experimental Design Assistant (EDA) is back online. Thank you for your patience while we undertook some core maintenance of the system.

NC3Rs @nc3rs.bsky.social · 17d

Please note that our Experimental Design Assistant (EDA) eda.nc3rs.org.uk will be offline tomorrow from 4pm (BST) for planned maintenance.

Full details 👇.

Esther Pearl @drejpearl.bsky.social · 20d

🚨⚠️The @nc3rs.bsky.social's Experimental Design Assistant (EDA) will be offline for planned maintenance on Tuesday 23 September from 4pm BST. We anticipate it will be back online by the morning of Wednesday 24 September. We apologise for any inconvenience caused.⚠️🚨

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NC3Rs @nc3rs.bsky.social · 22d

We use the term new approach methodologies (NAMs) to refer to full and partial replacement approaches for assessing chemical or drug toxicity. Non-animal methods describe full replacement approaches irrespective of the scientific discipline they are used in. Read more: nc3rs.org.uk/replacement-...

Replacement and NAMs – it’s all in the NAMe

The two most common uses of NAMs are to refer to non-animal methods and new approach methodologies. Here we explain the differences between these two terms.

nc3rs.org.uk

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NC3Rs @nc3rs.bsky.social · 22d

Are you a researcher, developer, or industry/regulatory user of NAMs?

Join our webinar with @brittoxsoc.bsky.social on how AI can improve safety assessment and reduce reliance on animals: nc3rs.org.uk/events/artif...

⏰ Registration closes: 24 September, 14.00
📅 Webinar: 25 September, 14.00 – 16.00

NC3Rs @nc3rs.bsky.social · Aug 27

Webinar: Future perspectives on artificial intelligence in safety assessment

Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.

📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...

Icons representing safety assessment (a chemical structure, a warning label, medicines, a lab flask, a computer, a rat and an environmental scene) connected in a microchip-style design. Text reads: AI in safety assessment.

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NC3Rs @nc3rs.bsky.social · 23d

New report from the NC3Rs, in collaboration with @abpi.bsky.social and MHRA, explores how New Approach Methodologies (NAMs) can transform the way new medicines are developed, harnessing cutting edge human relevant technologies and reducing reliance on animal testing.
nc3rs.org.uk/news/incorpo...

Report cover page: Incorporating new approach methodologies in the development of new medicines.

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NC3Rs @nc3rs.bsky.social · 24d

Final week to register! Join us at our next Technology Partn3Ring webinar to collaborate with academics and SMEs developing the latest 3Rs technologies in cancer research: nc3rs.org.uk/events/techn...

⏰Registration closes: Tuesday 23 September, 14.00
📅 Webinar: Wednesday 24 September, 14.00 – 15.15

NC3Rs @nc3rs.bsky.social · Sep 5

Are you interested in the latest 3Rs technologies in oncology research? Join us at our next Technology Partn3Ring webinar for opportunities to collaborate and access new 3Rs models.
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...

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NC3Rs @nc3rs.bsky.social · 28d

Join us next week to learn more about misconceptions around sex-inclusive research and how the Sex Inclusive Research Framework can be used by scientists, ethical review bodies and funders: nc3rs.org.uk/events/tackl...

📅 18 September, 15.00 – 16.00

📜 One hour of continuing professional development

A black mouse with a litter of pups in a laboratory cage.

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NC3Rs @nc3rs.bsky.social · 29d

Online conference: Dosing in animal models of neuroscience

@britpharmsoc.bsky.social ‬and @britishneuro.bsky.social ‬are hosting an online conference to explore 3Rs opportunities in preclinical dosing practices for neuropharmacology research.

📅 23 Sept, 9.30 – 16.15

👉 nc3rs.org.uk/events/dosin...

British Pharmacological Society and British Neuroscience Association logos, overlaid on an illustration of neurons. Text reads: 'Dosing in animal models of neuroscience. Time to challenge the status quo? 23 September 2025, online'.

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NC3Rs @nc3rs.bsky.social · Sep 9

Teach others how to use the EDA to design rigorous in vivo experiments that use the minimum number of animals: nc3rs.org.uk/events/ukrn-...

⏳ Registration closing soon: Wednesday 17 September

🤝Delivered by @drejpearl.bsky.social and @ukrepro.bsky.social

📅 Thursday 13 November, 10.00 – 16.00 (GMT)

NC3Rs @nc3rs.bsky.social · Aug 4

Looking for support to teach experimental design? Join our online workshop with @ukrepro.bsky.social on using the Experimental Design Assistant (EDA) to plan rigorous, reproducible animal studies.

📅 13 November, 10.00 – 16.00 (GMT)
❗ Registration closes: 17 September
👉 nc3rs.org.uk/events/ukrn-...

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NC3Rs @nc3rs.bsky.social · Sep 8

Congratulations to Dr Renata Nundes for winning the EUSAAT poster award at WC13! It is fantastic to see further global recognition of her in vitro assay to replace mice in snake antivenom potency testing, which was highly commended in this years’ International 3Rs Prize: nc3rs.org.uk/news/3rs-pri...

Dr Renata Nundes receiving a poster award from the European Society for Alternatives to Animal Testing (EUSAAT) at WC13 in Rio.

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NC3Rs @nc3rs.bsky.social · Sep 5

Are you interested in the latest 3Rs technologies in oncology research? Join us at our next Technology Partn3Ring webinar for opportunities to collaborate and access new 3Rs models.
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...

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NC3Rs @nc3rs.bsky.social · Sep 3

We are supporting in-person training workshops to promote the use of skin swabbing as a refined approach for genotyping zebrafish.
🐟 Suitable for technical staff and researchers
🤝 Personalised support in small groups
📍 Delivered at your facility (UK only)

Find out more: nc3rs.org.uk/training-wor...

A zebrafish is held in a hand net and swabbed.

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NC3Rs @nc3rs.bsky.social · Sep 2

Register now for two upcoming sessions on minimising animal suffering with early interventions and refined humane endpoints.

📅 11 and 16 September, 12.30 – 13.30
🙋🏻‍ For animal technicians, ethics committee members and researchers
📜 Certificates of attendance available
👉 nc3rs.org.uk/welfare-webi...

A staff member performing a welfare check on mice. They are standing in front of a rack of cages and holding one cage in their hand to inspect the mice.

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NC3Rs @nc3rs.bsky.social · Sep 1

Elliot Lilley is co-chairing a session on transitioning away from animal testing for vaccine quality control testing. He will be sharing our work to integrate the 3Rs into WHO guidelines and accelerate the global adoption of non-animal testing methods.

💉 Find out more: nc3rs.org.uk/events/world...

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NC3Rs @nc3rs.bsky.social · Aug 28

If you are attending WC13, make sure you connect with @james-barker.bsky.social and @drejpearl.bsky.social from our Experimental Design and Reporting team to learn more about resources to embed the 3Rs in the planning and publication of research.

📝 Find out more: nc3rs.org.uk/events/world...

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NC3Rs @nc3rs.bsky.social · Aug 27

Webinar: Future perspectives on artificial intelligence in safety assessment

Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.

📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...

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NC3Rs @nc3rs.bsky.social · Aug 26

⏳ Registration closing on Thursday 28 August!

Interested in driving the uptake and impact of 3Rs models and technologies through cross sector collaborations? Join us and the BBSRC in London on September 12 as we launch our new joint funding initiative.

Find out more: nc3rs.org.uk/events/nc3rs...

Icons representing NC3Rs Networks in oncology, cardiovascular science and new approach methodologies for safety assessment.

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NC3Rs @nc3rs.bsky.social · Aug 22

The next webinar in our welfare series will focus on refined humane endpoints and early interventions. Join us next month, across two lunchtime sessions, with expert speakers from academia and industry.

📅 Part 1: Thursday 11 September.
📅 Part 2: Tuesday 16 September.

👉 nc3rs.org.uk/welfare-webi...

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NC3Rs @nc3rs.bsky.social · Aug 20

Thank you to everyone who came to hear Esther talk about outputs from a joint workshop we held with @rspcalabanimal.bsky.social to discuss evidence-based refinements for amphibian welfare.

Visit our conference stand to find out more about NC3Rs resources relevant to research involving Xenopus.

Dr Esther Pearl, NC3Rs Programme Manager, standing behind a stall at a scientific conference. The table has a selection of NC3Rs resources. There is a poster on using the Experimental Design Assistant and the ARRIVE guidelines in teaching.

Dr Esther Pearl, NC3Rs Programme Manager, giving a talk at a scientific conference.

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NC3Rs @nc3rs.bsky.social · Aug 7

Thank you to the 100+ people from 24 countries who joined us at our 20th International 3Rs Prize ceremony to hear about work to replace animal-derived antibodies and in vivo antivenom tests, and to GSK who have sponsored the Prize from the start.

Watch the recording: nc3rs.org.uk/news/3rs-pri...

The picture shows in vitro techniques on the left, and a snake sitting on vials of antivenom on the right. Image credit: Steve Townsley.

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NC3Rs @nc3rs.bsky.social · Aug 6

As a commonly used species in research, interest in how to maintain and promote higher standards of welfare for zebrafish continues to grow.

This webinar adds to our resource library which includes guidance on all aspects of the use of zebrafish in research: nc3rs.org.uk/3rs-resource...

A technician working in a zebrafish aquaculture facility standing between rows of tanks.

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NC3Rs @nc3rs.bsky.social · Aug 6

Webinar recording and Q&A available: Improving the lives of laboratory zebrafish

Professor Robert Gerlai explores how optimising housing and handling improves zebrafish welfare and research quality.

👉 nc3rs.org.uk/3rs-resource-library/welfare-webinar-improving-lives-laboratory-zebrafish

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