NC3Rs
@nc3rs.bsky.social
A UK-based scientific organisation dedicated to helping the research community worldwide to identify, develop and use 3Rs technologies and approaches. https://nc3rs.org.uk/
We are delighted to publish a report with @abpi.bsky.social that examines the UK landscape in human relevant in vitro models. It will help inform wider policy, funding and infrastructure requirements to accelerate translation and deliver benefits for pharmaceutical R&D. nc3rs.org.uk/news/landsca...
A landscape review of human relevant pre-clinical model development in the UK
New report by the Association of the British Pharmaceutical Industry (ABPI) and the NC3Rs examines the UK's capabilities in developing human relevant pre-clinical models for medicine development.
nc3rs.org.uk
February 12, 2026 at 12:33 PM
We are delighted to publish a report with @abpi.bsky.social that examines the UK landscape in human relevant in vitro models. It will help inform wider policy, funding and infrastructure requirements to accelerate translation and deliver benefits for pharmaceutical R&D. nc3rs.org.uk/news/landsca...
We are working with @oga-community.bsky.social to recruit a cohort of early career researchers who will drive the validation and use of better antibodies. Are you our next Antibody Champion?
More details, eligibility and application process: nc3rs.org.uk/news/antibod...
More details, eligibility and application process: nc3rs.org.uk/news/antibod...
February 5, 2026 at 2:04 PM
We are working with @oga-community.bsky.social to recruit a cohort of early career researchers who will drive the validation and use of better antibodies. Are you our next Antibody Champion?
More details, eligibility and application process: nc3rs.org.uk/news/antibod...
More details, eligibility and application process: nc3rs.org.uk/news/antibod...
Registration deadline: If you would like to join us on Thursday (5 February) for our interactive webinar on commercialising NAMs technologies, please register by 13.00 on Wednesday.
Join the conversation about commercialising new approach methodologies (NAMs) for safety assessment in an interactive webinar featuring a live Q&A with expert method developers at our next NAMs Network event.
📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...
📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...
February 2, 2026 at 3:12 PM
Registration deadline: If you would like to join us on Thursday (5 February) for our interactive webinar on commercialising NAMs technologies, please register by 13.00 on Wednesday.
📢 Delivering the alternatives strategy – Pharmacokinetics and cardiac safety: nc3rs.org.uk/events/nc3rs...
Join us and @innovateuk.bsky.social to explore how research collaboration and innovation can deliver government targets to replace animal use in drug development.
📅 10 March, Central London
Join us and @innovateuk.bsky.social to explore how research collaboration and innovation can deliver government targets to replace animal use in drug development.
📅 10 March, Central London
January 30, 2026 at 10:46 AM
📢 Delivering the alternatives strategy – Pharmacokinetics and cardiac safety: nc3rs.org.uk/events/nc3rs...
Join us and @innovateuk.bsky.social to explore how research collaboration and innovation can deliver government targets to replace animal use in drug development.
📅 10 March, Central London
Join us and @innovateuk.bsky.social to explore how research collaboration and innovation can deliver government targets to replace animal use in drug development.
📅 10 March, Central London
Webinar recording – Replacing fish studies in chemical safety screening and regulatory environmental risk assessment: nc3rs.org.uk/3rs-resource...
Learn more about fish cell line-based reproductive toxicity assays developed by aQuaTox Solutions GmbH and Eawag through our SAFE CRACK IT Challenge.
Learn more about fish cell line-based reproductive toxicity assays developed by aQuaTox Solutions GmbH and Eawag through our SAFE CRACK IT Challenge.
Data-driven design of fish cell line-based reproductive toxicity assays
Outcomes from the SAFE CRACK IT Challenge to replace fish studies in chemical safety screening and environmental risk assessment.
nc3rs.org.uk
January 27, 2026 at 4:02 PM
Webinar recording – Replacing fish studies in chemical safety screening and regulatory environmental risk assessment: nc3rs.org.uk/3rs-resource...
Learn more about fish cell line-based reproductive toxicity assays developed by aQuaTox Solutions GmbH and Eawag through our SAFE CRACK IT Challenge.
Learn more about fish cell line-based reproductive toxicity assays developed by aQuaTox Solutions GmbH and Eawag through our SAFE CRACK IT Challenge.
Do you use artificial intelligence to improve toxicity prediction, support regulatory science or reduce the reliance on animal use in safety assessment?
Share your work and insights with the 3Rs Collaborative AI Initiative: forms.cloud.microsoft/pages/respon...
⏰ Survey closes: 21 February.
Share your work and insights with the 3Rs Collaborative AI Initiative: forms.cloud.microsoft/pages/respon...
⏰ Survey closes: 21 February.
January 26, 2026 at 10:18 AM
Do you use artificial intelligence to improve toxicity prediction, support regulatory science or reduce the reliance on animal use in safety assessment?
Share your work and insights with the 3Rs Collaborative AI Initiative: forms.cloud.microsoft/pages/respon...
⏰ Survey closes: 21 February.
Share your work and insights with the 3Rs Collaborative AI Initiative: forms.cloud.microsoft/pages/respon...
⏰ Survey closes: 21 February.
📢 Due to unforeseen circumstances this webinar has been postponed.
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
Welfare webinars
Practical welfare refinements to support positive change in day-to-day practice.
nc3rs.org.uk
January 21, 2026 at 3:07 PM
📢 Due to unforeseen circumstances this webinar has been postponed.
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
📢 Due to unforeseen circumstances this webinar has been postponed.
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
January 21, 2026 at 3:06 PM
📢 Due to unforeseen circumstances this webinar has been postponed.
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.
Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...
Join the conversation about commercialising new approach methodologies (NAMs) for safety assessment in an interactive webinar featuring a live Q&A with expert method developers at our next NAMs Network event.
📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...
📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...
January 21, 2026 at 12:10 PM
Join the conversation about commercialising new approach methodologies (NAMs) for safety assessment in an interactive webinar featuring a live Q&A with expert method developers at our next NAMs Network event.
📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...
📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...
Galleria mellonella offers researchers an alternative to traditional vertebrate animal models in many fields and the NC3Rs has supported a number of projects that demonstrate its versatility across a range of applications.
Explore our funding portfolio to find out more: nc3rs.org.uk/our-portfoli...
Explore our funding portfolio to find out more: nc3rs.org.uk/our-portfoli...
January 16, 2026 at 11:40 AM
Galleria mellonella offers researchers an alternative to traditional vertebrate animal models in many fields and the NC3Rs has supported a number of projects that demonstrate its versatility across a range of applications.
Explore our funding portfolio to find out more: nc3rs.org.uk/our-portfoli...
Explore our funding portfolio to find out more: nc3rs.org.uk/our-portfoli...
@gmrc.bsky.social has published its rearing manual online: nc3rs.org.uk/3rs-resource...
Reviewed by the NC3Rs and other external experts, this resource supports consistent, reliable and reproducible insect husbandry and empowers institutions to adopt wax moth larvae as a partial replacement model.
Reviewed by the NC3Rs and other external experts, this resource supports consistent, reliable and reproducible insect husbandry and empowers institutions to adopt wax moth larvae as a partial replacement model.
Galleria mellonella rearing manual
Developed by the Galleria Mellonella Research Centre at the University of Exeter, to support consistent, reliable and reproducible insect husbandry.
nc3rs.org.uk
January 16, 2026 at 11:40 AM
@gmrc.bsky.social has published its rearing manual online: nc3rs.org.uk/3rs-resource...
Reviewed by the NC3Rs and other external experts, this resource supports consistent, reliable and reproducible insect husbandry and empowers institutions to adopt wax moth larvae as a partial replacement model.
Reviewed by the NC3Rs and other external experts, this resource supports consistent, reliable and reproducible insect husbandry and empowers institutions to adopt wax moth larvae as a partial replacement model.
Are you involved in toxicology studies with dogs, minipigs or non-human primates? Register for our next welfare webinar to learn habituation techniques to refine their use in safety assessment: nc3rs.org.uk/events/welfa...
📅 29 January, 12.30 – 13.30 (GMT)
⏰ Registration closes: 28 January
📅 29 January, 12.30 – 13.30 (GMT)
⏰ Registration closes: 28 January
Welfare webinar: Habituation of minipigs, non-human primates and dogs for procedures in toxicology studies
Practical guidance to reduce stress during inhalation studies, blood sampling and ophthalmological exams.
nc3rs.org.uk
January 13, 2026 at 11:09 AM
Are you involved in toxicology studies with dogs, minipigs or non-human primates? Register for our next welfare webinar to learn habituation techniques to refine their use in safety assessment: nc3rs.org.uk/events/welfa...
📅 29 January, 12.30 – 13.30 (GMT)
⏰ Registration closes: 28 January
📅 29 January, 12.30 – 13.30 (GMT)
⏰ Registration closes: 28 January
Register for our online workshop ‘Rigorous experiments and clear communication with the Experimental Design Assistant’ as part of Love Methods Week this January: nc3rs.org.uk/events/love-...
📅 20 January, 9.00 – 11.00 (GMT)
⏰ Registration closes 19 January
📜 Certificates of attendance available
📅 20 January, 9.00 – 11.00 (GMT)
⏰ Registration closes 19 January
📜 Certificates of attendance available
January 9, 2026 at 1:11 PM
Register for our online workshop ‘Rigorous experiments and clear communication with the Experimental Design Assistant’ as part of Love Methods Week this January: nc3rs.org.uk/events/love-...
📅 20 January, 9.00 – 11.00 (GMT)
⏰ Registration closes 19 January
📜 Certificates of attendance available
📅 20 January, 9.00 – 11.00 (GMT)
⏰ Registration closes 19 January
📜 Certificates of attendance available
It's definitely worth a read. We were pleased to have the opportunity to provide evidence and contributions to the note given our expertise and long-standing programmes in this area working with researchers and organisations across the sector.
January 5, 2026 at 12:25 PM
It's definitely worth a read. We were pleased to have the opportunity to provide evidence and contributions to the note given our expertise and long-standing programmes in this area working with researchers and organisations across the sector.
2026 is continuing where 2025 left off with a focus on alternatives to animal use in research and testing. Today the Parliamentary Office of Science and Technology published a POSTnote on this topic highlighting the opportunities and challenges: post.parliament.uk/research-bri...
Technology alternatives to animals in life sciences research
How is the UK replacing animal testing with technology alternatives? What are the opportunities, risks and barriers?
post.parliament.uk
January 5, 2026 at 12:25 PM
2026 is continuing where 2025 left off with a focus on alternatives to animal use in research and testing. Today the Parliamentary Office of Science and Technology published a POSTnote on this topic highlighting the opportunities and challenges: post.parliament.uk/research-bri...
Developed in direct response to NC3Rs recommendations, new guidance from the World Health Organisation (@who.int) encourages manufacturers and regulators to replace or remove animal-based quality control methods for vaccines and biologics: nc3rs.org.uk/news/new-who...
New WHO guidelines on non-animal tests for quality control of biologics
Developed in direct response to NC3Rs recommendations, new guidance supports manufacturers and regulators to transition to non-animal testing strategies.
nc3rs.org.uk
December 18, 2025 at 10:00 AM
Developed in direct response to NC3Rs recommendations, new guidance from the World Health Organisation (@who.int) encourages manufacturers and regulators to replace or remove animal-based quality control methods for vaccines and biologics: nc3rs.org.uk/news/new-who...
Eight teams kick-started the commercialisation of their 3Rs tools and technologies this year through the BBSRC-NC3Rs ICURe Explore programme.
Learn more about their success and next steps to translate new approaches into real-world applications that minimise animal use: nc3rs.org.uk/news/driving...
Learn more about their success and next steps to translate new approaches into real-world applications that minimise animal use: nc3rs.org.uk/news/driving...
December 17, 2025 at 2:05 PM
Eight teams kick-started the commercialisation of their 3Rs tools and technologies this year through the BBSRC-NC3Rs ICURe Explore programme.
Learn more about their success and next steps to translate new approaches into real-world applications that minimise animal use: nc3rs.org.uk/news/driving...
Learn more about their success and next steps to translate new approaches into real-world applications that minimise animal use: nc3rs.org.uk/news/driving...
If you are interested in training methods for laboratory animals, the previous webinar in this series focusing on socialisation and positive reinforcement training for pigs and dogs is available to watch in our 3Rs resource library: nc3rs.org.uk/3rs-resource...
Welfare webinar: Socialisation and positive reinforcement training for pigs and dogs
Practical examples of how positive reinforcement techniques can be applied in a research environment to improve animal welfare.
nc3rs.org.uk
December 10, 2025 at 3:47 PM
If you are interested in training methods for laboratory animals, the previous webinar in this series focusing on socialisation and positive reinforcement training for pigs and dogs is available to watch in our 3Rs resource library: nc3rs.org.uk/3rs-resource...
Our next welfare webinar will focus on practical guidance to habituate dogs, minipigs and non-human primates to procedures in toxicology studies, minimising stress and refining their use in safety assessment.
📅 Thursday 29 January, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
📅 Thursday 29 January, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
Welfare webinar: Habituation of minipigs, non-human primates and dogs for procedures in toxicology studies
Practical guidance to reduce stress during inhalation studies, blood sampling and ophthalmological exams.
nc3rs.org.uk
December 10, 2025 at 3:47 PM
Our next welfare webinar will focus on practical guidance to habituate dogs, minipigs and non-human primates to procedures in toxicology studies, minimising stress and refining their use in safety assessment.
📅 Thursday 29 January, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
📅 Thursday 29 January, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
The OECD has agreed to develop new guidance that will reduce the number of fish used in some environmental toxicology studies. This is a result of work led by the NC3Rs and collaborators to understand and solve challenges in vitellogenin assessment.
Find out more: nc3rs.org.uk/news/new-int...
Find out more: nc3rs.org.uk/news/new-int...
December 5, 2025 at 11:14 AM
The OECD has agreed to develop new guidance that will reduce the number of fish used in some environmental toxicology studies. This is a result of work led by the NC3Rs and collaborators to understand and solve challenges in vitellogenin assessment.
Find out more: nc3rs.org.uk/news/new-int...
Find out more: nc3rs.org.uk/news/new-int...
Join @drejpearl.bsky.social at @unistrathclyde.bsky.social 3Rs day next week for an interactive workshop on using the Experimental Design Assistant to design rigorous in vivo experiments, with live support and guidance on hand.
📅 Friday 5 December
👉 Find out more: nc3rs.org.uk/events/unive...
📅 Friday 5 December
👉 Find out more: nc3rs.org.uk/events/unive...
November 27, 2025 at 3:57 PM
Join @drejpearl.bsky.social at @unistrathclyde.bsky.social 3Rs day next week for an interactive workshop on using the Experimental Design Assistant to design rigorous in vivo experiments, with live support and guidance on hand.
📅 Friday 5 December
👉 Find out more: nc3rs.org.uk/events/unive...
📅 Friday 5 December
👉 Find out more: nc3rs.org.uk/events/unive...
Registration is now closed. A recording of the webinar will be made available in our 3Rs resource library in due course: nc3rs.org.uk/3rs-resources
3Rs resource library
nc3rs.org.uk
November 26, 2025 at 1:10 PM
Registration is now closed. A recording of the webinar will be made available in our 3Rs resource library in due course: nc3rs.org.uk/3rs-resources
The strategy also recognises that animal research will remain important for years to come, acknowledging the need for animal research in parallel with the drive, coordination & funding required to achieve the ethical, scientific & economic benefits that innovations in animal alternatives can bring.
November 26, 2025 at 12:07 PM
The strategy also recognises that animal research will remain important for years to come, acknowledging the need for animal research in parallel with the drive, coordination & funding required to achieve the ethical, scientific & economic benefits that innovations in animal alternatives can bring.
There are clear actions outlined in the strategy to change the whole research ecosystem—from funders and universities to publishers and regulators—to enable rapid exploitation of scientific and technological opportunities to minimise reliance on animals in research.
November 26, 2025 at 12:07 PM
There are clear actions outlined in the strategy to change the whole research ecosystem—from funders and universities to publishers and regulators—to enable rapid exploitation of scientific and technological opportunities to minimise reliance on animals in research.
Our Chief Executive Vicky Robinson appears in @resprofnews.bsky.social today, in an opinion piece focusing on the UK government's ambitious strategy to replace the use of animals in research and testing: www.researchprofessionalnews.com/rr-news-uk-v....
UK’s plan to reduce animal experiments is strong - Research Professional News
Government strategy reflects recent progress and sets a path to the future, says Vicky Robinson
www.researchprofessionalnews.com
November 26, 2025 at 12:07 PM
Our Chief Executive Vicky Robinson appears in @resprofnews.bsky.social today, in an opinion piece focusing on the UK government's ambitious strategy to replace the use of animals in research and testing: www.researchprofessionalnews.com/rr-news-uk-v....