Nechama Wieder
@nechamawieder.bsky.social
PhD candidate @ University of Oxford
~ UTRs ~
~ UTRs ~
Reposted by Nechama Wieder
I wrote about how genetic risk works in the context of embryo selection and how people often think about it all wrong. A short 🧵:
What we talk about when we talk about risk
How embryo selection exploits our flawed intuitions about risk
open.substack.com
August 10, 2025 at 7:08 PM
I wrote about how genetic risk works in the context of embryo selection and how people often think about it all wrong. A short 🧵:
Reposted by Nechama Wieder
📣 We are recruiting! Please share!!
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
July 31, 2025 at 4:12 PM
📣 We are recruiting! Please share!!
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
Reposted by Nechama Wieder
New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells
In the presence of cell division errors, mammalian cells can pause in mitosis for tens of hours with little to no transcription, while still requiring continued translation for viability. These unique...
www.biorxiv.org
July 23, 2025 at 10:57 AM
New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Nechama Wieder
Deadline extended to August 1st!
Fully funded DPhil (PhD) in Statistical Genetics at Oxford, available to international candidates!
Fully funded DPhil (PhD) in Statistical Genetics at Oxford, available to international candidates!
Come join us! We have an exciting PhD opportunity in statistical genetics at the University of Oxford.
More info here: bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025.
Please share!
More info here: bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025.
Please share!
Research Studentships | statistics
bit.ly
July 21, 2025 at 11:39 AM
Deadline extended to August 1st!
Fully funded DPhil (PhD) in Statistical Genetics at Oxford, available to international candidates!
Fully funded DPhil (PhD) in Statistical Genetics at Oxford, available to international candidates!
Super excited to share our new review paper - The role of untranslated region variants in Mendelian disease!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The role of untranslated region variants in Mendelian disease: a review - European Journal of Human Genetics
European Journal of Human Genetics - The role of untranslated region variants in Mendelian disease: a review
www.nature.com
July 4, 2025 at 8:08 AM
Super excited to share our new review paper - The role of untranslated region variants in Mendelian disease!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nechama Wieder
Come join us! We have an exciting PhD opportunity in statistical genetics at the University of Oxford.
More info here: bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025.
Please share!
More info here: bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025.
Please share!
Research Studentships | statistics
bit.ly
June 9, 2025 at 1:55 PM
Come join us! We have an exciting PhD opportunity in statistical genetics at the University of Oxford.
More info here: bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025.
Please share!
More info here: bit.ly/biomedDPhil
🗓️ App deadline: June 30th 2025.
Please share!
Delighted to see my phenomenal phd supervisor get recognition for the all round fab scientist and super powerhouse she is! Go Nicky 🤩🥰
Congratulations to @nickywhiffin.bsky.social on being awarded the Balfour Lecturer! Her innovative contributions on the role of genetic variants in rare diseases are shaping the future of research and discovery. We look forward to her inspiring lecture!
genetics.org.uk/medals-and-p...
genetics.org.uk/medals-and-p...
November 24, 2024 at 11:50 AM
Delighted to see my phenomenal phd supervisor get recognition for the all round fab scientist and super powerhouse she is! Go Nicky 🤩🥰
As a recent graduate of a DPhil in Oxford could not recommend it more highly! Check these out and apply 😊
It's PhD application season here in Oxford with two weeks until the deadlines (3rd Dec) @universityofoxford.bsky.social
Here is a short 🧵 highlighting 3 amazing programs in the genomics, data science, statistics space 🩺🖥️🧬
Please share with anyone you think would be interested!
1/4
Here is a short 🧵 highlighting 3 amazing programs in the genomics, data science, statistics space 🩺🖥️🧬
Please share with anyone you think would be interested!
1/4
November 21, 2024 at 1:16 PM
As a recent graduate of a DPhil in Oxford could not recommend it more highly! Check these out and apply 😊