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neuralstemcells.bsky.social @neuralstemcells.bsky.social · 21d

Science fun on this beautiful Friday in Albany! The Capital District Postdoc Association held their annual symposium at the University at Albany. NSCI was well represented by CDPA president Sol Toruella, presenters Runia Roy & Catherine Hamann, and new postdocs Jenica Acheta & Alexis Guevara!

neuralstemcells.bsky.social @neuralstemcells.bsky.social · 23d

- with Brigitte Arduini, Susan Borden, Dhruv Sareen, Clive Svendsen, Paul Lee, Charles Ryan, Shilpa Kodati, Caroline Nyaiburi, Keith Wolsieffer, Eric Oh, Shuna Park, Glenna Ford, Keith Dionne and Sally Temple

@cellpress.bsky.social

neuralstemcells.bsky.social @neuralstemcells.bsky.social · 23d

Dr. Rajesh Rao and the terrific team at the University of Michigan Kellogg Eye Center performed each surgery and conducted clinical assessments.

@umich.edu

neuralstemcells.bsky.social @neuralstemcells.bsky.social · 23d

This first-in-human Phase 1/2a trial led by study PI Jeffrey Stern seeks to evaluate the safety and tolerability of adult RPE stem cell-derived RPE for treatment of dry age-related macular degeneration.

Safety and tolerability of RPESC-RPE transplantation in patients with dry age-related macular degeneration: Low-dose clinical outcomes

neuralstemcells.bsky.social @neuralstemcells.bsky.social · 23d

Big news! Early results from Cohort 1 of our Luxa Biotechnology-sponsored and #NEIfunded clinical trial are now available online at Cell Stem Cell!

Open Access Full Text | zurl.co/piAT4

#NIHfunded #MacularDegeneration #ClinicalTrials

Retinal pigment epithelium (RPE) cell loss in dry age-related macular degeneration leads to progressive vision decline. Stern and others implanted adult RPE stem cell-derived RPE progeny at a 4-week p...

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Sep 4

This work was supported by the National Institutes of Health and Luxa Biotechnology.

Full text | zurl.co/4hwI6
@isscr.org
@cellpress.bsky.social

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Sep 4

Using cell surface proteins identified with CITE-seq, we describe unique spatial patterns that suggest functional differences for RPE subpopulations.

- with Swapna Nandakumar, Taylor Bertucci, Thomas Kiehl, Steven Lotz, Yue Wang, Jacob Black, Skanda Sai, Jade Kozak, Brigitte Arduini & Sally Temple

Single-cell transcriptome and surfaceome profiling of the adult human retinal pigment epithelium

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Sep 4

Available now at @stemcellreports.bsky.social: Our #NEIfunded study led by Farhad Farjood, Nathan Boles and Jeffrey Stern reveals the surprising heterogeneity of retinal pigment epithelium cells in the human eye using single cell transcriptomics and proteomics.

Farjood et al. has set the stage for characterizing RPE heterogeneity by using single-cell sequencing technology to identify cell surface markers compatible with isolating each subpopulation for furth...

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neuralstemcells.bsky.social @neuralstemcells.bsky.social · Aug 11

🔊 Are you a detail-oriented PhD scientist with cell biology or #biomanufacturing experience? Interested in development of a novel clinical stage cell replacement therapy for dry age-related #MacularDegeneration (AMD)? We are #hiring!

Learn more: zurl.co/uwrDd

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jul 29

Today, Liz Fisher presents "PLD3 contributions to vascular dysfunction in the context of AD" during the poster session at #AAIC2025!

Poster | #107171
Time | 7:30AM – 4:15PM
Where | Exhibit Hall

AAIC | July 27-31, 2025 | Alzheimer's Association

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jul 27

Today at #AAIC2025: Taylor Bertucci presents "APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells."

Session | Dissecting molecular disease mechanisms
Time | 2:00 – 3:30PM
Location | Hall G

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jul 21

Coming up at #AAIC2025, Taylor Bertucci and Liz Fisher will present data related to APOE and PLD3 contributions to vascular dysfunction in #Alzheimers Disease. Check it out!

Alzheimer's Association | zurl.co/jgQ7m

The Alzheimer's Association International Conference is the world's largest forum for the dementia research community. Toronto, Canada, and online.

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jun 13

Our own Tom Kiehl, Taylor Bertucci and Brigitte Arduini will collaborate with this interdisciplinary team from @albany.edu, AIM Photonics, @binghamtonu.bsky.social, Hudson Valley Community College, and CUNY Bronx Community College.

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jun 13

📣 Just announced! Susan Sharfstein of @sunypolytechnic.bsky.social led a successful #FutureManufacturing grant application to develop next generation devices enabling advanced real-time measurement and manipulation in cellular systems.

#NSFfunded

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jun 3

Many thanks to Brigitte Arduini, Runia Roy, Dylan Murphy, Jade Kozak, Carmen Nazario, Liz Fisher, Susan Goderie, Habiba Khan, Sally Temple and Jeffrey Stern!

#biomanufacturing #CellTherapy

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jun 3

We had a terrific time with the #NIIMBLeXperience students hosted by ACPHS and the Stack Family Center for Biopharmaceutical Education and Training (CBET) program! These students are the future of pharmacy, biomanufacturing, bioengineering, and cell science. We love to see it!

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

neuralstemcells.bsky.social @neuralstemcells.bsky.social · Jun 2

Proceedings from the 2024 Global Tau Conference are available through the @alzassociation.bsky.social in collaboration with @CurePSP and the #RainwaterCharitableTrust.

Full text | zurl.co/0AnwI

Abstract Recent years have seen major advances in tau-associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic develo...

neuralstemcells.bsky.social @neuralstemcells.bsky.social · May 29

@reppaultonko.bsky.social, we were delighted to discuss our work with you today! We deeply appreciate your advocacy in support of our shared goal - to improve healthcare for patients and ultimately develop cures for Alzheimer's Disease, Macular Degeneration and other neurodegenerative conditions.

Rep. Paul Tonko @reppaultonko.bsky.social · May 29

Today, I stopped by @neuralstemcells.bsky.social new facility in Albany to learn more about how NIH grants are helping this small, nonprofit institution perform groundbreaking research and develop new therapies for neurodegenerative conditions like Alzheimer’s disease.

neuralstemcells.bsky.social @neuralstemcells.bsky.social · May 22

We were thrilled to host Dr. Kristen Brennand of @Yale University this week! She gave a terrific talk on "Using Stem Cells to Explore the Genetics Underlying Brain Disease."

#Schizophrenia
#StemCell

@kristenbrennand.bsky.social

Jared Lamson, Karen Bertasso-Hughes win 2025 CDPHP Workforce Challenge in Albany

neuralstemcells.bsky.social @neuralstemcells.bsky.social · May 17

Congrats to the winners and to everyone who completed the @CDPHP #WorkforceTeamChallenge!

@timesunion.com coverage | zurl.co/DDAjZ

Jared Lamson and Karen Bertasso-Hughes claimed top honors at the 2025 CDPHP Workforce Team Challenge in Albany, finishing first in the 3.5-mile race.

Jared Lamson, Karen Bertasso-Hughes win 2025 CDPHP Workforce Challenge in Albany

Reposted

Times Union @timesunion.com · May 16

Lamson broke away from runner-up Jack Huber of Delmar around the two-mile mark and never looked back in finishing in 17:06. On the women’s side, Karen Bertasso-Hughes of Selkirk added to her storied resume, claiming her sixth career Workforce Challenge title with a time of 20:05.

Jared Lamson and Karen Bertasso-Hughes claimed top honors at the 2025 CDPHP Workforce Team Challenge in Albany, finishing first in the 3.5-mile race.

www.timesunion.com