Microbial cell-free DNA next-generation sequencing (mcfDNA-NGS) had a positive diagnostic impact in 30% of patients with fever of unknown origin (FUO). Pre

Mold plasma cell-free DNA (cfDNA) PCR is a promising non-invasive diagnostic modality for early diagnosis of invasive mold disease (IMD) in immunocompromised patients. Although mold cfDNA PCR has been shown to be highly accurate, the value of invasive procedures to collect specimens for conventional fungal diagnostics following plasma cfDNA testing remains unclear.

This Clinical Insights discusses how the methicillin-resistant Staphylococcus aureus (MRSA) nares swab may be used alongside disease prevalence and clinical factors to determine when MRSA coverage is ...

Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

In the management of immunocompromised patients with neutropenia and Gram-negative bloodstream infection, short antimicrobial courses (≤10 days) had comparable propensity score-adjusted 90-day outcom...