g adverse reactions, and ensuring patient compliance with prescribed regimens. The aim of this study is to assess the degree of compliance with nimodipine use, causes of noncompliance and explore if adherence to nimodipine in clinical practice correlates with improved neurological outcomes as indicated by modified Rankin Scale (mRS) scores.METHODS: A retrospective study of consecutive aSAH admissions to a comprehensive stroke center over a 67-month period. Compliance was defined as receiving at least 80% of the recommended doses of nimodipine over 21 days. A chart review was performed to explore the reasons for noncompliance. We examined hospital disposition at discharge and 90-day mRS, adjusted for severity of aSAH. Compliance rates before and after a pharmacist-guided intervention were also examined.RESULTS: Among 141 patients, the overall compliance rate was just 30%. The leading reasons for missed doses included hypotension (68.1%) and patients being off the unit (56%). Compliance was not associated with improvement in 90-day mRS scores for low-grade aSAH (P=0.3638) and high-grade aSAH (P=0.227). After pharmacist-guided intervention, compliance improved from 18.2% to 43.8%.CONCLUSION: There is a high rate of noncompliance with nimodipine use in aSAH, but it did not significantly impact patient outcomes. Although pharmacist interventions improved compliance, full compliance remains challenging....

elational design to explore the relationship between intolerance of uncertainty, symptom severity, and disease self-management in MS patients. A total of 105 MS patients followed in the neurology clinic were included in the study. RESULTS: A positive moderate correlation was found between the participants’ mean scores on the Intolerance of Uncertainty Scale and the mean scores on the Monitoring My Multiple Sclerosis Scale (r=0.429; P0.01), while a negative moderate correlation was found between the participants’ mean scores on the Intolerance of Uncertainty Scale and the mean scores on the Multiple Sclerosis Self-Management Scale (r=−0.558; P0.01). CONCLUSIONS: Intolerance of uncertainty explained 18% of the total variance in symptom severity and 30% of the total variance in self-management of PwMS patients (P0.01). Intolerance of uncertainty increased symptom severity and decreased self-management level in PwMS and was an important predictor of both symptom severity and self-management. Nurses should address intolerance of uncertainty and take initiatives to reduce uncertainty in the care and treatment process of PwMS....

elational design to explore the relationship between intolerance of uncertainty, symptom severity, and disease self-management in MS patients. A total of 105 MS patients followed in the neurology clinic were included in the study. RESULTS: A positive moderate correlation was found between the participants’ mean scores on the Intolerance of Uncertainty Scale and the mean scores on the Monitoring My Multiple Sclerosis Scale (r=0.429; P0.01), while a negative moderate correlation was found between the participants’ mean scores on the Intolerance of Uncertainty Scale and the mean scores on the Multiple Sclerosis Self-Management Scale (r=−0.558; P0.01). CONCLUSIONS: Intolerance of uncertainty explained 18% of the total variance in symptom severity and 30% of the total variance in self-management of PwMS patients (P0.01). Intolerance of uncertainty increased symptom severity and decreased self-management level in PwMS and was an important predictor of both symptom severity and self-management. Nurses should address intolerance of uncertainty and take initiatives to reduce uncertainty in the care and treatment process of PwMS....

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and O'Malley's 5-stage framework. We systematically searched the PubMed and CINAHL databases through December 2023 for studies of interventions for SDB after stroke that could be implemented by nursing staff. Data on intervention characteristics, stroke and SDB types, timing, and outcomes were extracted. RESULTS: From 2866 screened articles, 10 studies met inclusion criteria. From these, we identified 5 distinct interventions: positional therapy, oropharyngeal muscle exercises, physical exercise, compression devices, and education. As confirmed by polysomnography or home sleep testing, 9 studies targeted obstructive sleep apnea. CONCLUSION: This review provides the first analysis of nurse-implementable interventions for poststroke SDB. The identified interventions appear promising for improving SDB parameters, particularly when adapted for stroke-specific care. Future research on developing standardized protocols that integrate these interventions into comprehensive care pathways will enhance the role of nurses in the early detection and management of poststroke SDB....

and O'Malley's 5-stage framework. We systematically searched the PubMed and CINAHL databases through December 2023 for studies of interventions for SDB after stroke that could be implemented by nursing staff. Data on intervention characteristics, stroke and SDB types, timing, and outcomes were extracted. RESULTS: From 2866 screened articles, 10 studies met inclusion criteria. From these, we identified 5 distinct interventions: positional therapy, oropharyngeal muscle exercises, physical exercise, compression devices, and education. As confirmed by polysomnography or home sleep testing, 9 studies targeted obstructive sleep apnea. CONCLUSION: This review provides the first analysis of nurse-implementable interventions for poststroke SDB. The identified interventions appear promising for improving SDB parameters, particularly when adapted for stroke-specific care. Future research on developing standardized protocols that integrate these interventions into comprehensive care pathways will enhance the role of nurses in the early detection and management of poststroke SDB....

LETTER TO THE EDITOR: Bridging the Gap Between Routine Practice and Patient Experience: A Call for Empathy in Postoperative Neurological CareRead the article...