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onclive.bsky.social
OncLive
@onclive.bsky.social
930 followers 140 following 2.5K posts
Healthcare publisher of oncology focused articles, videos, panel discussions, and much more that run the gamut of oncology care and management.
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onclive.bsky.social
Cevostamab-Based Combos Could Represent Next Bispecific Antibody Approach in R/R #Myeloma

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Cevostamab-Based Combos Could Represent Next Bispecific Antibody Approach in R/R Myeloma | OncLive
Joshua Richter, MD, discusses the evaluation of the FcRH5 x CD3 bispecific antibody in multiple myeloma.
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November 25, 2025 at 5:49 PM
onclive.bsky.social
Subcutaneous Toripalimab Plus Chemo Meets PK End Points in Recurrent/Metastatic Nonsquamous #NSCLC

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Subcutaneous Toripalimab Plus Chemo Meets PK End Points in Recurrent/Metastatic Nonsquamous NSCLC | OncLive
Subcutaneous toripalimab generated non-inferior efficacy and safety outcomes vs the IV formulation in recurrent/metastatic non squamous NSCLC.
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November 25, 2025 at 3:46 PM
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Sacituzumab Tirumotecan Plus Pembrolizumab Improves PFS in PD-L1+ Advanced NSCLC #lcsm #oncology www.onclive.com/view/sacituz...
Sacituzumab Tirumotecan Plus Pembrolizumab Improves PFS in PD-L1+ Advanced NSCLC | OncLive
Sacituzumab tirumotecan plus pembrolizumab improved PFS as first-line treatment in PD-L1–positive advanced NSCLC.
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November 24, 2025 at 4:04 PM
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Patient Factors Drive Chemotherapy Decision-Making in Metastatic #PancreaticCancer @mdanderson.bsky.social #PancreaticCancerAwareness

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Patient Factors Drive Chemotherapy Decision-Making in Metastatic Pancreatic Cancer | OncLive
Shubham Pant, MD, MBBS, explores frontline chemotherapy decision-making in metastatic pancreatic cancer.
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November 24, 2025 at 3:42 PM
onclive.bsky.social
Vorasidenib Shows Rapid Real-World Uptake in IDH-Mutated Glioma @neuroonc.bsky.social #SNO2025 #oncology #glioma
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Vorasidenib Shows Rapid Real-World Uptake in IDH-Mutated Glioma | OncLive
Vorasidenib is being integrated in the real-world setting for the treatment of patients with IDH-mutated glioma.
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November 24, 2025 at 1:11 PM
onclive.bsky.social
8F-Fluciclovine Imaging Differentiates Progression From Treatment-Related Changes in Brain Metastases @uwsph.bsky.social @neuroonc.bsky.social #SNO25 #oncology www.onclive.com/view/18f-flu...
18F-Fluciclovine Imaging Differentiates Progression From Treatment-Related Changes in Brain Metastases | OncLive
18F-Fluciclovine PET/MRI detected disease progression and ruled out disease in non-progressors among patients with solid tumor brain metastases.
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November 23, 2025 at 11:29 PM
onclive.bsky.social
Erdafitinib Is Safe and Shows Preliminary Efficacy in F3T3 Fusion+ Glioma @neuroonc.bsky.social #SNO25 #oncology www.onclive.com/view/erdafit...
Erdafitinib Is Safe and Shows Preliminary Efficacy in F3T3 Fusion+ Glioma | OncLive
Erdafitinib had a safety profile that was deemed tolerable in patients with recurrent or progressive IDH wild-type glioma harboring F3T3 gene fusions.
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November 23, 2025 at 3:31 AM
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Eflornithine Plus Lomustine Extends PFS, OS in Reclassified WHO Grade 3 IDH-Mutated Astrocytoma @huntsmancancer.bsky.social #SNO2025 #btsm #oncology www.onclive.com/view/eflorni...
Eflornithine Plus Lomustine Extends PFS, OS in Reclassified WHO Grade 3 IDH-Mutated Astrocytoma | OncLive
Eflornithine plus lomustine produced superior OS and PFS outcomes vs lomustine in WHO grade 3 IDH-mutated astrocytoma.
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November 23, 2025 at 2:24 AM
onclive.bsky.social
Temozolomide Plus Radiotherapy Yields Survival Benefit in IDH-Mutant LGG @neuroonc.bsky.social #SNO2025 #oncology
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Temozolomide Plus Radiotherapy Yields Survival Benefit in IDH-Mutant LGG | OncLive
Temozolomide plus radiotherapy significantly improved OS vs radiotherapy alone in IDH-mutant low-grade gliomas without codeletions of 1q and 19q.
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November 23, 2025 at 1:57 AM
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Mirdametinib Shows Improved ORR Over Time in NF1-Associated Symptomatic Plexiform Neurofibroma #SNO2025 #oncology www.onclive.com/view/mirdame...
Mirdametinib Shows Improved ORR Over Time in NF1-Associated Symptomatic Plexiform Neurofibroma | OncLive
Long-term ReNeu results showed deeper, more durable responses to mirdametinib in NF1-PN with extended treatment in both adults and children.
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November 22, 2025 at 9:15 PM
onclive.bsky.social
CAR T-Cell Therapy Shows Early Safety in Recurrent Brain/Leptomeningeal Mets From HER2+ Breast Cancer
@cityofhope.bsky.social @neuroonc.bsky.social #SNO25 #bcsm #oncology www.onclive.com/view/car-t-c...
CAR T-Cell Therapy Proves Safe in Recurrent Brain/Leptomeningeal Mets From HER2+ Breast Cancer | OncLive
HER2-directed CAR T-cell therapy was safe in patients with brain/leptomeningeal metastases from HER2-positive breast cancer.
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November 22, 2025 at 8:47 PM
onclive.bsky.social
B7-H3–Directed CAR T-Cell Therapy Has Acceptable Safety Profile in Recurrent Glioblastoma @uncdeptmedicine.bsky.social @unclineberger.bsky.social #SNO25 #oncology www.onclive.com/view/b7-h3-d...
B7-H3–Directed CAR T-Cell Therapy Has Acceptable Safety Profile in Recurrent Glioblastoma | OncLive
B7-H3–directed CAR T-cell therapy given intraventricularly was well tolerated and showed early efficacy signals in patients with recurrent glioblastoma.
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November 22, 2025 at 5:01 AM
onclive.bsky.social
Mirdametinib Generates Responses and Is Safe in Pediatric Low-Grade Glioma @stjude.bsky.social @neuroonc.bsky.social #SNO25 #oncology #glioma #braincancer www.onclive.com/view/mirdame...
Mirdametinib Generates Responses and Is Safe in Pediatric Low-Grade Glioma | OncLive
Mirdametinib had clinical activity and was deemed well tolerated in MEK inhibitor–naive pediatric patients with recurrent/progressive low-grade glioma.
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November 22, 2025 at 2:34 AM
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Regorafenib Plus Temozolomide and RT Shows Early Signs of Tolerability in MGMT-Methylated, IDH Wild-Type Glioblastoma #SNO2025 #btsm #oncology www.onclive.com/view/regoraf...
Regorafenib Plus Temozolomide and RT Shows Early Signs of Tolerability in MGMT-Methylated, IDH Wild-Type Glioblastoma | OncLive
The RP2D of regorafenib when given with temozolomide and radiotherapy in patients with MGMT-methylated, IDH wild-type glioblastoma was 120 mg.
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November 22, 2025 at 2:04 AM
onclive.bsky.social
Vorasidenib Plus Temozolomide Demonstrates Safety in IDH1/2+ Glioma
@neuroonc.bsky.social #SNO2025 #oncology #braincancer #glioma
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Vorasidenib Plus Temozolomide Demonstrates Safety in IDH1/2+ Glioma | OncLive
Vorasidenib plus temozolomide was safe in glioma harboring IDH1/2 mutations.
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November 22, 2025 at 1:41 AM
onclive.bsky.social
🚨 BREAKING NEWS 🚨: @fda.gov Approves Perioperative Enfortumab Vedotin Plus Pembrolizumab for Cisplatin-Ineligible MIBC

Here's what you should know about the decision: www.onclive.com/view/fda-app...

#oncology #fdanews
November 21, 2025 at 5:29 PM
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FDA Accepts NDA for Zidesamtinib in ROS1+ Advanced NSCLC After a Prior TKI #oncology #lcsm #NSCLC
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FDA Accepts NDA for Zidesamtinib in ROS1+ Advanced NSCLC After a Prior TKI | OncLive
Will the FDA approve zidesamtinib for ROS1-positive advanced non–small cell lung cancer after a prior TKI?
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November 21, 2025 at 4:51 PM
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CELMoDs Aim to Build on Established IMiDs in Multiple Myeloma Management @mountsinainyc.bsky.social #mmsm #hematology
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CELMoDs Aim to Build on Established IMiDs in Multiple Myeloma Management | OncLive
Joshua Richter, MD, discusses the exploration of CELMoDs in the treatment of patients with multiple myeloma.
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November 21, 2025 at 1:22 PM
onclive.bsky.social
The Essential But Often Complex Role of Numbers and Measurements in Oncology @cityofhope.bsky.social #oncology
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The Essential But Often Complex Role of Numbers and Measurements in Oncology | OncLive
Maurie Markman, MD, discusses the evolving role of measurements in cancer care.
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November 20, 2025 at 7:52 PM
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FDA Clears Oncomine Dx Target Test as Companion Diagnostic for Sevabertinib in NSCLC #oncology #lcsm #NSCLC
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FDA Clears Oncomine Dx Target Test as Companion Diagnostic for Sevabertinib in NSCLC | OncLive
The FDA OKs the Oncomine Dx Target Test to identify patients with HER2 TKD–mutant NSCLC eligible for sevabertinib, enabling targeted treatment selection.
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November 20, 2025 at 6:28 PM
onclive.bsky.social
Venetoclax-Enhanced RBAC Shows Promise in High-Risk Mantle Cell Lymphoma #oncology #MCL
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Venetoclax-Enhanced RBAC Shows Promise in High-Risk Mantle Cell Lymphoma | OncLive
Carlo Visco, MD, discusses phase 2 FIL_V-RBAC results showing venetoclax plus RBAC achieved a meaningful PFS and manageable toxicity in high-risk MCL.
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November 20, 2025 at 6:22 PM
onclive.bsky.social
@fda.gov Approves Osvyrti and Jubereq in High Fracture Risk Populations, Including in Breast and Prostate Cancer.

#oncology #bcsm #pcsm

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FDA Approves Osvyrti and Jubereq in High Fracture Risk Populations, Including in Breast and Prostate Cancer | OncLive
Denosumab-desu (Osvyrti and Jubereq) received FDA approval in the same indications as reference denosumab (Prolia and Xgeva).
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November 20, 2025 at 6:22 PM
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Moffitt Study Reveals Way to Spark Immune Hotspots That Attack Tumors @moffittnews.bsky.social #oncology
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Moffitt Study Reveals Way to Spark Immune Hotspots That Attack Tumors | OncLive
Investigators at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary lymphoid-like structures.
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November 20, 2025 at 5:00 PM
onclive.bsky.social
Targeting OXPHOS With Lixumistat Could Lessen Chemoresistance in Pancreatic Cancer @mdanderson.bsky.social #oncology #pancreaticcancer
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Targeting OXPHOS With Lixumistat Could Lessen Chemoresistance in Pancreatic Cancer | OncLive
Shubham Pant, MD, MBBS, and Ryan W. Huey, MD, MS, discuss OXPHOS pathway inhibition in pancreatic cancer with lixumistat.
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November 20, 2025 at 4:55 PM
onclive.bsky.social
BREAKING❗: @fda.gov Grants Accelerated Approval to Sevabertinib in HER2-Mutated Nonsquamous NSCLC

Learn more about this regulatory decision below. 👇
🔗https://www.onclive.com/view/fda-grants-accelerated-approval-to-sevabertinib-in-her2-mutated-nonsquamous-nsclc

#lcsm #oncology #FDAapproved
November 19, 2025 at 8:05 PM