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#mCRPC #ProstateCancer #OncologyTools #CancerCare #ClinicalOncology #DigitalHealth #OncologyApp #AdvancedProstateCancer #oncologytools
✅ Imfinzi (durvalumab) becomes the first perioperative immunotherapy approved in the US for early gastric & GEJ cancers.
Phase III MATTERHORN data show strong outcomes:
🔹 29% lower risk of progression, recurrence or reduced OS.
🔹 22% lower risk of reduced OS vs. standard chemo
✅ Imfinzi (durvalumab) becomes the first perioperative immunotherapy approved in the US for early gastric & GEJ cancers.
Phase III MATTERHORN data show strong outcomes:
🔹 29% lower risk of progression, recurrence or reduced OS.
🔹 22% lower risk of reduced OS vs. standard chemo
🔔 PharmaEssentia, announces that positive results from its pivotal Phase 3 SURPASS-ET clinical trial have been published in The Lancet Haematology.
➡️ The SURPASS-ET compared ropeginterferon alfa-2b vs anagrelide in hydroxyurea-resistant/intolerant ET with leukocytosis.
🔔 PharmaEssentia, announces that positive results from its pivotal Phase 3 SURPASS-ET clinical trial have been published in The Lancet Haematology.
➡️ The SURPASS-ET compared ropeginterferon alfa-2b vs anagrelide in hydroxyurea-resistant/intolerant ET with leukocytosis.
🔔 The EC approves expanded use of Breyanzi® (lisocabtagene maraleucel; liso-cel) for R/R Mantle Cell Lymphoma (MCL).
🧬 In the TRANSCEND MCL trial, 82.7% of patients responded, with 71.6% achieving a complete response, and over 50% maintaining response at 24 months.
🔔 The EC approves expanded use of Breyanzi® (lisocabtagene maraleucel; liso-cel) for R/R Mantle Cell Lymphoma (MCL).
🧬 In the TRANSCEND MCL trial, 82.7% of patients responded, with 71.6% achieving a complete response, and over 50% maintaining response at 24 months.
🔔 The FDA has approved pembrolizumab in combination with enfortumab vedotin-ejfv as a neoadjuvant + adjuvant treatment for adults with MIBC who are ineligible for cisplatin.
🎯 The major efficacy outcome measure was EFS assessed by blinded independent central review.
🔔 The FDA has approved pembrolizumab in combination with enfortumab vedotin-ejfv as a neoadjuvant + adjuvant treatment for adults with MIBC who are ineligible for cisplatin.
🎯 The major efficacy outcome measure was EFS assessed by blinded independent central review.
🔔 FDA grants accelerated approval to Sevabertinib for adults with metastatic non-squamous NSCLC harboring HER2 TKD activating mutations after prior systemic therapy.
➡️ FDA also clears the Oncomine Dx Target Test as a companion diagnostic to identify eligible patients.
🔔 FDA grants accelerated approval to Sevabertinib for adults with metastatic non-squamous NSCLC harboring HER2 TKD activating mutations after prior systemic therapy.
➡️ FDA also clears the Oncomine Dx Target Test as a companion diagnostic to identify eligible patients.
🔔 The FDA has granted full approval to daratumumab and hyaluronidase-fihj plus VCd for newly diagnosed light chain (AL) amyloidosis, converting its 2021 accelerated approval to traditional approval.
✅ This decision is supported by results from the ANDROMEDA Phase 3 trial.
🔔 The FDA has granted full approval to daratumumab and hyaluronidase-fihj plus VCd for newly diagnosed light chain (AL) amyloidosis, converting its 2021 accelerated approval to traditional approval.
✅ This decision is supported by results from the ANDROMEDA Phase 3 trial.
📢 FDA approves selumetinib(KOSELUGO, AstraZeneca Pharmaceuticals LP) for adults with NF1 experiencing symptomatic, inoperable plexiform neurofibromas.
🔹FDA previously approved selumetinib capsules and granules for pediatric patients 1 year of age and older for this indication.
📢 FDA approves selumetinib(KOSELUGO, AstraZeneca Pharmaceuticals LP) for adults with NF1 experiencing symptomatic, inoperable plexiform neurofibromas.
🔹FDA previously approved selumetinib capsules and granules for pediatric patients 1 year of age and older for this indication.
✅ EU approves Libtayo® (cemiplimab) as the first immunotherapy for adjuvant treatment of CSCC at high risk of recurrence after surgery and radiation.
📉 Phase 3 C-POST trial: Significant improvement in disease-free survival with a 68% reduction in recurrence.
✅ EU approves Libtayo® (cemiplimab) as the first immunotherapy for adjuvant treatment of CSCC at high risk of recurrence after surgery and radiation.
📉 Phase 3 C-POST trial: Significant improvement in disease-free survival with a 68% reduction in recurrence.
✅ FDA grants full approval to Amgen's IMDELLTRA® (tarlatamab-dlle) in extensive stage small cell lung cancer (ES-SCLC).
🎯 Phase 3 DeLLphi-304 shows 40% reduction in risk of death vs chemo.
🔗 Read more: bit.ly/ONCOnews20N3
#ONCOnews #OncoAlert #OncEd #Oncology #CancerUpdates
✅ FDA grants full approval to Amgen's IMDELLTRA® (tarlatamab-dlle) in extensive stage small cell lung cancer (ES-SCLC).
🎯 Phase 3 DeLLphi-304 shows 40% reduction in risk of death vs chemo.
🔗 Read more: bit.ly/ONCOnews20N3
#ONCOnews #OncoAlert #OncEd #Oncology #CancerUpdates
The CTCAE criteria are designed to standardise adverse event reporting in oncology research and practice.
#ONCOassist #CTCAEv6 #ToxicityGrading #AdverseEvents #OncologyTools #DigitalHealth #CancerCare #ClinicalOncology #OncologyApp
The CTCAE criteria are designed to standardise adverse event reporting in oncology research and practice.
#ONCOassist #CTCAEv6 #ToxicityGrading #AdverseEvents #OncologyTools #DigitalHealth #CancerCare #ClinicalOncology #OncologyApp
🆕 EU approves Roche’s Lunsumio® (mosunetuzumab) subcutaneous (SC) for relapsed/refractory follicular lymphoma — offering durable responses even in later-line disease.
⏱️ New SC option cuts administration time to ~1 minute, supporting greater treatment flexibility for patients.
🆕 EU approves Roche’s Lunsumio® (mosunetuzumab) subcutaneous (SC) for relapsed/refractory follicular lymphoma — offering durable responses even in later-line disease.
⏱️ New SC option cuts administration time to ~1 minute, supporting greater treatment flexibility for patients.
🔔 The European Commission has approved subcutaneous KEYTRUDA® (pembrolizumab) for all adult EU-approved indications — becoming the first and only subcutaneous immune checkpoint inhibitor in Europe.
🔗 Read more: bit.ly/ONCOnews20N-1
#ONCOnews #OncoAlert #OncEd #Oncology
🔔 The European Commission has approved subcutaneous KEYTRUDA® (pembrolizumab) for all adult EU-approved indications — becoming the first and only subcutaneous immune checkpoint inhibitor in Europe.
🔗 Read more: bit.ly/ONCOnews20N-1
#ONCOnews #OncoAlert #OncEd #Oncology
🔹Stay up to date with the latest adverse event standards.
🔹Search and grade adverse events instantly.
🔹Streamline your documentation.
🔹Improve communication and safety in daily oncology practice.
➡️ CTCAE v4 & v5 are still available in the app.
🔹Stay up to date with the latest adverse event standards.
🔹Search and grade adverse events instantly.
🔹Streamline your documentation.
🔹Improve communication and safety in daily oncology practice.
➡️ CTCAE v4 & v5 are still available in the app.
✅ FDA approves EPKINLY® (epcoritamab-bysp) in combination with Rituximab and Lenalidomide for relapsed/refractory follicular lymphoma!
💥 First-ever bispecific antibody combination approved, delivering superior PFS & response rates in Phase 3 EPCORE FL-1 study.
✅ FDA approves EPKINLY® (epcoritamab-bysp) in combination with Rituximab and Lenalidomide for relapsed/refractory follicular lymphoma!
💥 First-ever bispecific antibody combination approved, delivering superior PFS & response rates in Phase 3 EPCORE FL-1 study.
📣 Phase 3 results show ZIIHERA® (zanidatamab) delivers strong efficacy as a leading HER2-targeted therapy.
✅ Its combination with TEVIMBRA® (tislelizumab) + chemotherapy is emerging as a new first-line standard of care in HER2-positive gastroesophageal cancer.
📣 Phase 3 results show ZIIHERA® (zanidatamab) delivers strong efficacy as a leading HER2-targeted therapy.
✅ Its combination with TEVIMBRA® (tislelizumab) + chemotherapy is emerging as a new first-line standard of care in HER2-positive gastroesophageal cancer.
💊 Roche’s giredestrant becomes the first oral SERD to show superior iDFS vs standard endocrine therapy.
📈 A potential new standard of care emerges - lidERA trial delivers a second Phase III success after evERA trial.
🔗 Read more: bit.ly/ONCOnews18N-1
💊 Roche’s giredestrant becomes the first oral SERD to show superior iDFS vs standard endocrine therapy.
📈 A potential new standard of care emerges - lidERA trial delivers a second Phase III success after evERA trial.
🔗 Read more: bit.ly/ONCOnews18N-1
✅ FDA Approves First Ever Perjeta Biosimilar!
📢 Poherdy (pertuzumab-dpzb, Shanghai Henlius Biologics Co. Ltd.) is now approved as an interchangeable biosimilar to Perjeta(pertuzumab, Genentech Inc.) for HER2+ breast cancer across metastatic, neoadjuvant, and adjuvant settings.
✅ FDA Approves First Ever Perjeta Biosimilar!
📢 Poherdy (pertuzumab-dpzb, Shanghai Henlius Biologics Co. Ltd.) is now approved as an interchangeable biosimilar to Perjeta(pertuzumab, Genentech Inc.) for HER2+ breast cancer across metastatic, neoadjuvant, and adjuvant settings.
✅ The FDA has approved ziftomenib (Komzifti), a menin inhibitor, for adults with relapsed/refractory AML harboring an NPM1 mutation who lack satisfactory treatment options.
🎯 Decision supported by the KO-MEN-001 trial evaluating efficacy and safety in 112 patients.
✅ The FDA has approved ziftomenib (Komzifti), a menin inhibitor, for adults with relapsed/refractory AML harboring an NPM1 mutation who lack satisfactory treatment options.
🎯 Decision supported by the KO-MEN-001 trial evaluating efficacy and safety in 112 patients.
#ONCOassist #MASCC #FebrileNeutropenia #OncologyTools #DigitalHealth #SupportiveCare
#ONCOassist #MASCC #FebrileNeutropenia #OncologyTools #DigitalHealth #SupportiveCare
✅ The FDA has approved Promega’s OncoMate® MSI Dx Analysis System as a companion diagnostic for KEYTRUDA® (pembrolizumab) + LENVIMA® (lenvatinib) in advanced endometrial carcinoma.
🔬 This MSI technology helps identify patients with microsatellite stable (MSS) disease.
✅ The FDA has approved Promega’s OncoMate® MSI Dx Analysis System as a companion diagnostic for KEYTRUDA® (pembrolizumab) + LENVIMA® (lenvatinib) in advanced endometrial carcinoma.
🔬 This MSI technology helps identify patients with microsatellite stable (MSS) disease.
Meet ONCO-IQ — the new quiz-based feature inside #ONCOassist that turns learning into action.
Fast. Evidence-based.Interactive.
🎯 Take the quiz → buff.ly/kno5ObA
#Oncology #OncoAlert 🚨
@oncoalert.bsky.social
@myesmo.bsky.social
@ascopost.bsky.social
Meet ONCO-IQ — the new quiz-based feature inside #ONCOassist that turns learning into action.
Fast. Evidence-based.Interactive.
🎯 Take the quiz → buff.ly/kno5ObA
#Oncology #OncoAlert 🚨
@oncoalert.bsky.social
@myesmo.bsky.social
@ascopost.bsky.social
@ONCOassist
. A fast, visual guide for clinicians & surgeons.
Watch now: youtu.be/WwFUqUa6OJI
#LiverAnatomy #Couinaud #OncologyTools #ONCOassist #Radiology #CTscan #Oncoalert
@HundalJasmin
@ONCOassist
. A fast, visual guide for clinicians & surgeons.
Watch now: youtu.be/WwFUqUa6OJI
#LiverAnatomy #Couinaud #OncologyTools #ONCOassist #Radiology #CTscan #Oncoalert
@HundalJasmin
📢 Reducing Daunorubicin (DNR) in induction therapy for children with favorable-prognosis B-lineage ALL shows promising results in Phase III AIEOP-BFM ALL 2009.
💊 Aim: Maintain high cure rates while minimizing anthracycline-related toxicity.
📢 Reducing Daunorubicin (DNR) in induction therapy for children with favorable-prognosis B-lineage ALL shows promising results in Phase III AIEOP-BFM ALL 2009.
💊 Aim: Maintain high cure rates while minimizing anthracycline-related toxicity.
✅ Update from HARMONi-A Study Conducted by Akeso in China:
🔹 Ivonescimab + chemotherapy significantly improved overall survival (HR = 0.74) in 2L+ EGFRm NSCLC.
🔹 Marks the first Phase III trial of Ivonescimab to achieve a statistically significant OS benefit.
✅ Update from HARMONi-A Study Conducted by Akeso in China:
🔹 Ivonescimab + chemotherapy significantly improved overall survival (HR = 0.74) in 2L+ EGFRm NSCLC.
🔹 Marks the first Phase III trial of Ivonescimab to achieve a statistically significant OS benefit.