Orthopaedic Research Society
LightNews LightNews
banner
orssociety.bsky.social
Orthopaedic Research Society
@orssociety.bsky.social
510 followers 390 following 520 posts
The home of your global orthopaedic research community. Accelerating musculoskeletal discovery to improve health. #orthoresearch #ORSAmbassador #ORSSMC #ORSSML #ORS2026
Posts Replies Media Videos
Pinned
orssociety.bsky.social
Orthopaedic Research Society @orssociety.bsky.social · 4d
Join us for the virtual ORS Annual Business Meeting of the Membership on Dec 10 at 11 AM CT. Hear updates on the Society’s financials, membership data, and what’s new at ORS. Learn about member benefits and share your questions or feedback. Register here: https://ors.memberclicks.net/2025mbm#/
orssociety.bsky.social
🚨 One week left to submit your applications for the #ORS2026 Dr. Peter Roughley Award! This award provides $2,000 to support travel for a mentor–trainee team conducting research in spine, disc, and cartilage biology. Apply by December 15: https://www.ors.org/ors-dr-peter-roughley-award.
December 8, 2025 at 8:21 PM
orssociety.bsky.social
🎓 The Chronicle of Higher Education is hosting a free webinar series on the administration’s impact on higher education. Join Sarah Brown and Rick Seltzer for insights from Washington. Final session: Dec 15. On-demand recordings available. Register here: https://bit.ly/48nIOOs
December 8, 2025 at 6:15 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
Manmeet S. Dhiman & coauthors found that human disc degeneration is accompanied by a loss of anterior annulus fibrosus interlamellar matrix integrity as assessed by peel tests: onlinelibrary.wiley....
(a) Schematic of the AF sample harvested (light shaded portion) from the individuals with degenerative disc disease and non-DD individuals. Sample dimension parameters labeled as: (1) Circumferential Length, (2) Disc Height/Tissue Width, (3) Radial Length, and (4) Peel Length. The blue and orange shaded faces of the sample showcase the change in orientation of the sample from (a) to (b). (b) Schematic showing the preparation of the peel test sample. The tissue strip on the left shows the Peel Length in red and the projected incision in white. The tissue is cut along the white line using a number 11 scalpel blade. The tissue strip on the right with the incision shows the annular tabs that are used to clamp the tissue for the peel test. Wp is the tissue width (disc height), Fp is the force experienced by the tissue for delamination, and Fc is the force exerted by the clamp to stretch and delaminate the tissue. Clamp force, Fc, is assumed to be equal to the peel force, Fp.
December 5, 2025 at 9:56 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Wonhee Lee & coauthors performed an evaluation of the baseplate position and screws in reverse total shoulder arthroplasty using 3D printed patient-specific instrumentation: onlinelibrary.wiley.com/doi/10.1002/...
Schematic figure for both normal and malpositioned baseplate and screws.
December 5, 2025 at 10:53 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Linus Hötzel & coauthors examined differences in the movement of the glenoid over the humeral head between subject-specific and generalized glenohumeral motion: onlinelibrary.wiley.com/doi/10.1002/... #shoulder #biomechanics
Method for obtaining generalized motion trajectories. Subject-specific motion trajectories captured with bi-planar fluoroscopy are available from an open-source. Data-processing included time normalization, offset removal, sub-selection of the forward motion, and averaging. The average translation was based on polynomial regression and the average rotation based on quaternion averaging. For each subject, the generalized motion (based on the average of all subjects) was also applied and compared to the subject-specific motion.
December 8, 2025 at 12:46 AM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Masatake Matsuoka & coauthors found that a retinoid antagonist attenuates bone growth inhibition after growth plate injury in mice. Learn more in JOR: onlinelibrary.wiley.com/doi/10.1002/...
The actions of 7 C, the retinoid antagonist on stimulation of GP repair.
December 8, 2025 at 4:59 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Issei Shinohara & coauthors performed dynamic analysis of ultrasound images of the median nerve using particle image velocimetry to look for differences in nerve motion in people with carpal tunnel syndrome: onlinelibrary.wiley.com/doi/10.1002/...
(a) Ultrasound linear probe is applied to the inlet of the carpal tunnel to delineate the median nerve. With this view depicted, fingers are flexed and extended. (b) Median nerve short-axis image (red arrows) at the inlet of the carpal tunnel.
December 4, 2025 at 10:53 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Ketsia Seide & coauthors found that a siglec-15 antibody promotes high quality bone formation in adult female mice with osteogenesis imperfecta: onlinelibrary.wiley.com/doi/10.1002/...
Micro-CT 3D images of WT and OIM trabecular bone.
December 5, 2025 at 4:59 PM
Reposted by Orthopaedic Research Society
isfrfractures.bsky.social
We’re pleased to share our latest ISFR Spotlight Interview, featuring Dr.-Ing. Edoardo Borgiani (KU Leuven). In this conversation, Dr. Borgiani discusses multi-scale computational modeling for fracture healing 🦴. Check it out here: www.linkedin.com/feed/update/...
November 30, 2025 at 6:09 PM
orssociety.bsky.social
The University of Limerick will host the 31st Annual Bioengineering Conference, Jan 23–24, 2026. Join keynote talks, workshops, & networking. #ORSAmbassador David Hoey, PhD will be on-site promoting #musculoskeletal research. Learn more & register: https://www.ors.org/ambassadorevents/
December 5, 2025 at 7:00 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
Ying Zhang & coauthors found that diurnal asymmetric loading modulates cell phenotype in intervertebral disc: onlinelibrary.wiley....
Representative Safranin O/Fast Green staining images of sagittal sections of IVDs. Bovine coccygeal IVD organ explant cultured with different loading regimes for 7 days and 6 μm sections from EDTA-decalcified and paraffin-embedded tissue. Scale bar: 2 mm.
December 5, 2025 at 3:13 PM
orssociety.bsky.social
Our 2025 #WebinarWednesday series wrapped with 1,520 participants across 26 webinars. Scientific talks, career sessions, socials & more! Missed one? On-demand recordings are open to all, no cost for ORS Members in the LearnORS Video Library: https://www.ors.org/learnorsvideolibrary/
December 5, 2025 at 4:58 PM
orssociety.bsky.social
Submit your abstracts for the @isfrfractures.bsky.social 19th Biennial Meeting! Join us May 6–8, 2026 in Berlin with the AO Germany Conference. Registration is open, plan your trip and share your work in #fracturerepair, bone regeneration & #orthopaedic trauma. https://www.ors.org/2026isfrmeeting/
December 4, 2025 at 8:02 PM
Reposted by Orthopaedic Research Society
orssociety.bsky.social
🏆 Nominate a leader for the #ORS2026 @isfrfractures.bsky.social Lifetime Achievement Award, honoring impactful contributions in fracture repair, bone regeneration, bone biology, and trauma. The deadline for nominations is January 12. Learn more: www.ors.org/isfr-lifetim...
October 20, 2025 at 7:48 PM
orssociety.bsky.social
Join us for the virtual ORS Annual Business Meeting of the Membership on Dec 10 at 11 AM CT. Hear updates on the Society’s financials, membership data, and what’s new at ORS. Learn about member benefits and share your questions or feedback. Register here: https://ors.memberclicks.net/2025mbm#/
December 4, 2025 at 3:36 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Yoshiaki Ito & coauthors performed a comparison of external rotation torque of short external rotator muscles in hip flexion position. This information is important for techniques aimed at preventing dislocation after total hip arthroplasty: onlinelibrary.wiley.com/doi/10.1002/...
Schematic diagram of muscle lines of action projected onto a plane perpendicular to the hip rotation axis in the neutral and flexed positions.
December 2, 2025 at 4:59 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
Kyung Wook Kim & coauthors performed a temporal study in rats to look at the interplay of angiogenesis and osteogenesis in non-dtabilized incomplete tibial fractures: onlinelibrary.wiley.com/doi/10.1002/...
H&E stained tissue sections of the tibia bone fracture site taken at 1 week, 2 weeks, 4 weeks, and 8 weeks post-fracture induction showing the tissue formation over time. Compared to the fractured bone, pristine bone tissue showed relatively low numbers of cells within the bone matrix and appeared relatively uneventful in terms of microstructural changes. Spongy bony callus can be observed within the medullary space after 1 week. Thickened and externally expanded bony callus can be observed at 2 weeks. Highly consolidated bony callus is observed at 4 weeks although the fracture gap is still highly discernable. No visible trace of the fracture can be observed at 8 weeks post-fracture induction (Scale bar = 200 µm).
December 2, 2025 at 10:53 PM
Reposted by Orthopaedic Research Society
jorthopres.bsky.social
There is currently no method for objectively identifying and quantifying hip instability. Edward Godbold & coauthors used dynamic joint space during physiological loading to Objectively measure hip stability: onlinelibrary.wiley.com/doi/10.1002/...
Biplane radiography data collection and processing. (A) Participants walked (shown; 1.1 ± 0.2 m/s) and squatted while (B) synchronized biplane radiographs were collected (50 frames/s, 80 kV, 320 mA, 3.2 ms pulse width). (C) CT scans (0.3 × 0.3 × 0.625 mm) were collected and (D) used to create 3D bone models. (E) Bone motion was tracked using a validated process that matched digitally reconstructed radiographs from CT-based bone models to the biplane radiographs to determine (F) the range in minimum subchondral bone distance.
December 3, 2025 at 4:59 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
Maryam Kazemi Naeini & coauthors found evidence for a causal relationship between cytomegalovirus infection and chronic back pain. Learn more in this JOR Spine SHORT COMMUNICATION:
Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One‐Sample Mendelian Randomization Study
Background Chronic back pain (CBP) is a major cause of disability globally. While its etiology is multifactorial, specific contributing genetic and environmental factors remain to be discovered. Par...
onlinelibrary.wiley.com
December 1, 2025 at 3:45 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
Wei Wang & coauthors found that disk senescence and reduced height in aged mice are linked to upregulated expression of senescence-associated phenotypes and macrophage polarization markers, highlighting potential targets for therapeutic intervention: onlinelibrary.wiley....
Mouse IVD images showing tissue staining and DR showing the disk height statistics. (A) Saffron O, Fast Green, and Alcian Blue staining (scale bar: 200 μm, magnification ×10); (B, C) DR and caudal vertebrae of adult and aged mice and height statistics; (D) IVD altered histological scoring statistic (*p < 0.05, ****p < 0.0001). Each point on the statistical chart represents a mouse.
December 1, 2025 at 5:45 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
This review by Kaiyuan Zheng & coauthors emphasizes that macrophage polarization is a pivotal regulator of intervertebral disc degeneration pathology, providing promising therapeutic targets: onlinelibrary.wiley....
Diagram of the mechanism by which macrophage polarization influences IVDD by modulating the inflammatory microenvironment.
December 1, 2025 at 6:45 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
Sabina M. Pinto & coauthors present their findings on the relationship between lumbar multifidus morphometry and pain/disability in people with chronic nonspecific low back pain after considering demographics, fear-avoidance beliefs, insomnia, and spinal degenerative changes: onlinelibrary.wiley....
Case reporting and completeness of data collection.
December 1, 2025 at 7:26 PM
Reposted by Orthopaedic Research Society
jorspine.bsky.social
Karthikeyan Rajagopal & coauthors found that in vivo measurements reveal increased nucleus pulposus lactate and oxygen concentrations in a goat model of intervertebral disc degeneration: onlinelibrary.wiley....
(A) Representative Alcian blue and picrosirius red (ABPR) and (B) hematoxylin and eosin (H&E) stained mid-sagittal histological sections of healthy and degenerate goat discs; scale = 5 mm. Note the presence of endplate damage and associated eruption of disc tissue into adjacent vertebrae in the severely degenerate disc (arrow). (C–G) Semi-quantitative histological grading of NP cellularity, NP matrix, AF organization, AF/NP border, and CEP structure. (H) Overall histological grade. *p < 0.05 versus healthy; N = 3–6; median and interquartile range.
December 1, 2025 at 8:46 PM
orssociety.bsky.social
Check out this @jorspine.bsky.social Editor’s Pick: Researchers tested potassium iodide (KI) as a new contrast agent to improve micro-CT imaging of the nucleus pulposus for earlier detection of IVD degeneration. Read more: bit.ly/3XyGQVk
High‐Resolution 3‐Dimensional Micro‐CT Imaging of Intervertebral Discs Using a Novel Contrast Agent
This study introduces the first use of a contrast agent (potassium iodide) to enhance 3D imaging of the nucleus pulposus within an intact intervertebral disc (IVD). This method was used to demonstrat...
bit.ly
December 3, 2025 at 8:51 PM
Reposted by Orthopaedic Research Society
orssociety.bsky.social
It’s time to renew your ORS Membership for 2026!
We’ve expanded member benefits to give you more ways to learn, engage, and connect: access to all 8 ORS Sections, LearnORS, expanded #ORS2026 access + lunch Sat/Sun, and advocacy resources. Join or renew: https://www.ors.org/join-ors/
November 18, 2025 at 10:00 PM