Pablo Perez Lopez
@pabloplopez.bsky.social
🩺 UAM MD Y5 | 👥 Medical Student Leadership ACC | 🫀CNIC Student | 🗞️ SoMe Editor @escardio.bsky.social #CardioSky
#EHJCVI 🚀 A new accelerated stress-perfusion CMR protocol shows non-inferior per-vessel diagnostic accuracy (<5%) and comparable per-patient accuracy, saving over 20 min per scan. Could this be the future for evaluating suspected angina? 🫀 👉 Read more: doi.org/10.1093/ehjc... #MedSky
November 25, 2025 at 12:26 PM
#EHJCVI 🚀 A new accelerated stress-perfusion CMR protocol shows non-inferior per-vessel diagnostic accuracy (<5%) and comparable per-patient accuracy, saving over 20 min per scan. Could this be the future for evaluating suspected angina? 🫀 👉 Read more: doi.org/10.1093/ehjc... #MedSky
#EHJCVI 🧬 Should Lp(a) be considered a biomarker of bioprosthetic valve vulnerability? Elevated Lp(a) emerges as an independent predictor of structural valve degeneration, particularly in stenotic/mixed phenotypes 🫀🔍 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
November 20, 2025 at 7:20 PM
#EHJCVI 🧬 Should Lp(a) be considered a biomarker of bioprosthetic valve vulnerability? Elevated Lp(a) emerges as an independent predictor of structural valve degeneration, particularly in stenotic/mixed phenotypes 🫀🔍 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
#EHJCVI 🌡️ What is the link between stress and PCAT attenuation? ↑ Attenuation is associated with ↑ IL-6, ↑ TNF-α, and ↑ plaque volume, though not with vulnerable plaque features or coronary stenosis. Chronic stress may shape these relationships🫀 👉 doi.org/10.1093/ehjc... #MedSky #CVImaging
November 17, 2025 at 10:48 AM
#EHJCVI 🌡️ What is the link between stress and PCAT attenuation? ↑ Attenuation is associated with ↑ IL-6, ↑ TNF-α, and ↑ plaque volume, though not with vulnerable plaque features or coronary stenosis. Chronic stress may shape these relationships🫀 👉 doi.org/10.1093/ehjc... #MedSky #CVImaging
#EHJCVI 🫀 Can CMR help detect cardiac allograft vasculopathy?
Myocardial perfusion reserve offers high sensitivity and a high negative predictive value, with a suggested cut-off of 2.2 for ruling out disease 🔍 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
Myocardial perfusion reserve offers high sensitivity and a high negative predictive value, with a suggested cut-off of 2.2 for ruling out disease 🔍 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
November 16, 2025 at 7:26 PM
#EHJCVI 🫀 Can CMR help detect cardiac allograft vasculopathy?
Myocardial perfusion reserve offers high sensitivity and a high negative predictive value, with a suggested cut-off of 2.2 for ruling out disease 🔍 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
Myocardial perfusion reserve offers high sensitivity and a high negative predictive value, with a suggested cut-off of 2.2 for ruling out disease 🔍 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
#EHJCVI 🫀 What are the effects of disopyramide and mavacamten on myocardial mechanics? Only mavacamten reduced LV mechanical dispersion and GWW, while improving GWE in obstructive HCM. LVMD <72 ms at follow-up is useful to predict VT or SCA ⚡ doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
November 15, 2025 at 6:06 PM
#EHJCVI 🫀 What are the effects of disopyramide and mavacamten on myocardial mechanics? Only mavacamten reduced LV mechanical dispersion and GWW, while improving GWE in obstructive HCM. LVMD <72 ms at follow-up is useful to predict VT or SCA ⚡ doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
#EHJCVI 🫀 What is the prognostic value of RVol/LAV in ventricular functional MR undergoing M-TEER? Lower RVol/LAV is linked to a higher risk of heart failure hospitalization (HR 1.25) and serves as an independent predictor 📊⚠️ 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
November 14, 2025 at 8:31 PM
#EHJCVI 🫀 What is the prognostic value of RVol/LAV in ventricular functional MR undergoing M-TEER? Lower RVol/LAV is linked to a higher risk of heart failure hospitalization (HR 1.25) and serves as an independent predictor 📊⚠️ 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
#EHJCVI 🩻 What predicts persistent LAA patency after closure on CCTA? 💡 At 45 days, having two factors: side-gap leak prox area >37.7 mm², radial diameter >3 mm, or angle >39.4° — predicted persistence with 94% sens and 70% spec 🫀 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
November 13, 2025 at 9:06 PM
#EHJCVI 🩻 What predicts persistent LAA patency after closure on CCTA? 💡 At 45 days, having two factors: side-gap leak prox area >37.7 mm², radial diameter >3 mm, or angle >39.4° — predicted persistence with 94% sens and 70% spec 🫀 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
#EHJCVI 🤖 Can #whyCMR improve prognostic assessment in AL cardiac amyloidosis? DL analysis of LGE distinguishes patients within the same Mayo stage but with different outcomes, capturing prognostic features beyond amyloid-affected areas 🫀✨ 👉 Read more: doi.org/10.1093/ehjc... #MedSky
November 12, 2025 at 4:34 PM
#EHJCVI 🤖 Can #whyCMR improve prognostic assessment in AL cardiac amyloidosis? DL analysis of LGE distinguishes patients within the same Mayo stage but with different outcomes, capturing prognostic features beyond amyloid-affected areas 🫀✨ 👉 Read more: doi.org/10.1093/ehjc... #MedSky
#EHJCVI 🏃♂️ Dilated athlete’s heart or mild dilated cardiomyopathy? CMR reveals that septal fibrosis is rare in athletes, who show lower native T1 and ECV, but higher RVEDVi and MBP, with an AUC ≈ 0.85 for ECV 🫀📊 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
November 11, 2025 at 12:44 PM
#EHJCVI 🏃♂️ Dilated athlete’s heart or mild dilated cardiomyopathy? CMR reveals that septal fibrosis is rare in athletes, who show lower native T1 and ECV, but higher RVEDVi and MBP, with an AUC ≈ 0.85 for ECV 🫀📊 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
EHJCVI 🫀 How does thin-cap fibroatheroma affect non-culprit lesions? Patients with DM show more of these plaques and face higher risks of NCL-MACE after AMI, but long-term prognosis worsens in both DM and non-DM patients ⚠️🔍 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
November 10, 2025 at 9:06 AM
EHJCVI 🫀 How does thin-cap fibroatheroma affect non-culprit lesions? Patients with DM show more of these plaques and face higher risks of NCL-MACE after AMI, but long-term prognosis worsens in both DM and non-DM patients ⚠️🔍 👉 Read more: doi.org/10.1093/ehjc... #MedSky @jgrapsa.bsky.social
#EHJCVI 🫀 Long-axis shortening or GLS in CMR? A UK Biobank study shows that longitudinal shortening provides a similar predictive value for cardiovascular outcomes, with a hazard ratio of 0.78 for incident heart failure 📊💡 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
November 9, 2025 at 7:10 PM
#EHJCVI 🫀 Long-axis shortening or GLS in CMR? A UK Biobank study shows that longitudinal shortening provides a similar predictive value for cardiovascular outcomes, with a hazard ratio of 0.78 for incident heart failure 📊💡 👉 Read more: doi.org/10.1093/ehjc... #whyCMR #MedSky @jgrapsa.bsky.social
Reposted by Pablo Perez Lopez
Must read...
#EHJCVI When should we use #EchoFirst in cardiovascular emergencies and critical care?
The new EACVI–ACVC consensus highlights its key role in cardiogenic shock, AMI, ADHF, and more 🚨🫀📘 👉 Read more: doi.org/10.1093/ehjc... @EACVIPresident @ACVCPresident #MedSky
The new EACVI–ACVC consensus highlights its key role in cardiogenic shock, AMI, ADHF, and more 🚨🫀📘 👉 Read more: doi.org/10.1093/ehjc... @EACVIPresident @ACVCPresident #MedSky
November 7, 2025 at 3:03 PM
Must read...
#EHJCVI 📈 What is the impact of long-term adiposity in early adulthood? Higher body roundness index is associated with a greater risk of coronary artery calcium over 25 years (OR 2.59) and increased all-cause mortality 🫀⚠️ Read more 👉 doi.org/10.1093/ehjc... #CVImaging
November 8, 2025 at 12:55 PM
#EHJCVI 📈 What is the impact of long-term adiposity in early adulthood? Higher body roundness index is associated with a greater risk of coronary artery calcium over 25 years (OR 2.59) and increased all-cause mortality 🫀⚠️ Read more 👉 doi.org/10.1093/ehjc... #CVImaging
#EHJCVI 🫀 What are the differences between current diastolic dysfunction guidelines? 📖 This editorial by @jgrapsa, @argulian, @OttoSmiseth reviews key differences and their impact 👉 Read more: doi.org/10.1093/ehjc... #EchoFirst #CVImaging #Echocardiography
November 7, 2025 at 11:17 AM
#EHJCVI 🫀 What are the differences between current diastolic dysfunction guidelines? 📖 This editorial by @jgrapsa, @argulian, @OttoSmiseth reviews key differences and their impact 👉 Read more: doi.org/10.1093/ehjc... #EchoFirst #CVImaging #Echocardiography
#EHJCVI When should we use #EchoFirst in cardiovascular emergencies and critical care?
The new EACVI–ACVC consensus highlights its key role in cardiogenic shock, AMI, ADHF, and more 🚨🫀📘 👉 Read more: doi.org/10.1093/ehjc... @EACVIPresident @ACVCPresident #MedSky
The new EACVI–ACVC consensus highlights its key role in cardiogenic shock, AMI, ADHF, and more 🚨🫀📘 👉 Read more: doi.org/10.1093/ehjc... @EACVIPresident @ACVCPresident #MedSky
November 6, 2025 at 6:09 PM
#EHJCVI When should we use #EchoFirst in cardiovascular emergencies and critical care?
The new EACVI–ACVC consensus highlights its key role in cardiogenic shock, AMI, ADHF, and more 🚨🫀📘 👉 Read more: doi.org/10.1093/ehjc... @EACVIPresident @ACVCPresident #MedSky
The new EACVI–ACVC consensus highlights its key role in cardiogenic shock, AMI, ADHF, and more 🚨🫀📘 👉 Read more: doi.org/10.1093/ehjc... @EACVIPresident @ACVCPresident #MedSky
#EHJCVI🫀What’s the impact of VExUS in acute heart failure management and risk stratification?💧Improvement is linked to better mortality outcomes, while persistent abnormalities may require extended diuretic titration or closer monitoring 📖 Read more 👉 doi.org/10.1093/ehjc... @jgrapsa.bsky.social
October 5, 2025 at 4:14 PM
#EHJCVI🫀What’s the impact of VExUS in acute heart failure management and risk stratification?💧Improvement is linked to better mortality outcomes, while persistent abnormalities may require extended diuretic titration or closer monitoring 📖 Read more 👉 doi.org/10.1093/ehjc... @jgrapsa.bsky.social
#EHJCVI 🫀 How can we better select NICM patients for ICD prevention therapy? ⚡ Does LGE provide additional prognostic value? 🔍 Midwall LGE and scar location significantly influence MAACE risk and can guide treatment decisions 📖 Read more 👉 doi.org/10.1093/ehjc... #CardioSky @jgrapsa.bsky.social
October 4, 2025 at 4:26 PM
#EHJCVI 🫀 How can we better select NICM patients for ICD prevention therapy? ⚡ Does LGE provide additional prognostic value? 🔍 Midwall LGE and scar location significantly influence MAACE risk and can guide treatment decisions 📖 Read more 👉 doi.org/10.1093/ehjc... #CardioSky @jgrapsa.bsky.social
🌟 Excited to share that I will be a SoMe ambassador for this year #ESCCongress in Madrid 🇪🇸 I will be sharing highlights in CV imaging, as well as CHD, VHD and PH 🫀🫁 Stay tuned for live updates! #CVImaging #CHD #PulmonaryHypertension #ValvularHeartDisease
🎉 The wait is almost over! #ESCCongress kicks off tomorrow!
Meet our amazing Social Media Ambassadors 🙌
Follow their journey, join the conversation, and catch the hottest updates & highlights straight from Madrid!💙
Meet our amazing Social Media Ambassadors 🙌
Follow their journey, join the conversation, and catch the hottest updates & highlights straight from Madrid!💙
August 28, 2025 at 11:50 AM
🌟 Excited to share that I will be a SoMe ambassador for this year #ESCCongress in Madrid 🇪🇸 I will be sharing highlights in CV imaging, as well as CHD, VHD and PH 🫀🫁 Stay tuned for live updates! #CVImaging #CHD #PulmonaryHypertension #ValvularHeartDisease
#EHJIMP 🫁 Can we use free-breathing ECG-triggered cine CMR instead of SSFP? 🔄 Both methods show good agreement 🫀 Ideal for patients with arrhythmias or limited breath-hold capacity 🧪 Similar diagnostic performance to SSFP 📖 Read more 👉 doi.org/10.1093/ehji... #CardioSky @jgrapsa.bsky.social
June 17, 2025 at 7:52 PM
#EHJIMP 🫁 Can we use free-breathing ECG-triggered cine CMR instead of SSFP? 🔄 Both methods show good agreement 🫀 Ideal for patients with arrhythmias or limited breath-hold capacity 🧪 Similar diagnostic performance to SSFP 📖 Read more 👉 doi.org/10.1093/ehji... #CardioSky @jgrapsa.bsky.social
#EHJCVI 📢 Call for Papers: 🫀 Special Issue on CHD
📤 Original, reviews, clinical case series, technical notes & innovations are welcomed!
📚 Topics: tech advancements, clinical applications, multidisciplinary integration, challenges
🔗 Learn more academic.oup.com/ehjimp/pages... #CardioSky
📤 Original, reviews, clinical case series, technical notes & innovations are welcomed!
📚 Topics: tech advancements, clinical applications, multidisciplinary integration, challenges
🔗 Learn more academic.oup.com/ehjimp/pages... #CardioSky
June 16, 2025 at 6:55 PM
#EHJCVI 📢 Call for Papers: 🫀 Special Issue on CHD
📤 Original, reviews, clinical case series, technical notes & innovations are welcomed!
📚 Topics: tech advancements, clinical applications, multidisciplinary integration, challenges
🔗 Learn more academic.oup.com/ehjimp/pages... #CardioSky
📤 Original, reviews, clinical case series, technical notes & innovations are welcomed!
📚 Topics: tech advancements, clinical applications, multidisciplinary integration, challenges
🔗 Learn more academic.oup.com/ehjimp/pages... #CardioSky
#EHJCVI 🔍 What LV TTE markers predict outcomes in systemic right ventricles? 📏 Systemic RV diameter & FAC, LV ESDi & LV FAC are independent predictors of mortality & transplantation in ACHD patients 📚 Want to know more? 👉 doi.org/10.1093/ehjc... #CardioSky @jgrapsa.bsky.social @escardio.bsky.social
June 16, 2025 at 6:41 PM
#EHJCVI 🔍 What LV TTE markers predict outcomes in systemic right ventricles? 📏 Systemic RV diameter & FAC, LV ESDi & LV FAC are independent predictors of mortality & transplantation in ACHD patients 📚 Want to know more? 👉 doi.org/10.1093/ehjc... #CardioSky @jgrapsa.bsky.social @escardio.bsky.social
#EHJIMP 🐭 What’s the best method to assess LVEF & volumes in a rat model of DOX-cardiotoxicity? 🌀4D & M-mode show the lowest bias and narrowest limits of agreement ✅ Strong correlation across most parameters! 🔍 Read more 👉 doi.org/10.1093/ehji... #CardioSky @jgrapsa.bsky.social @escardio.bsky.social
June 15, 2025 at 8:34 PM
#EHJIMP 🐭 What’s the best method to assess LVEF & volumes in a rat model of DOX-cardiotoxicity? 🌀4D & M-mode show the lowest bias and narrowest limits of agreement ✅ Strong correlation across most parameters! 🔍 Read more 👉 doi.org/10.1093/ehji... #CardioSky @jgrapsa.bsky.social @escardio.bsky.social
#EHJCVI 🔄 How is LV-A & RV-PA coupling in HFpEF with high LVEF? ⚠️ Higher risk of death & readmission, but why? 📈 These patients show ↑ left Ees/Ea 🫀 Meanwhile, TAPSE/PASP predicts event-free survival, independent of LVEF 📖 Read more 👉 doi.org/10.1093/ehjc... #CardioSky @jgrapsa.bsky.social
June 15, 2025 at 8:24 PM
#EHJCVI 🔄 How is LV-A & RV-PA coupling in HFpEF with high LVEF? ⚠️ Higher risk of death & readmission, but why? 📈 These patients show ↑ left Ees/Ea 🫀 Meanwhile, TAPSE/PASP predicts event-free survival, independent of LVEF 📖 Read more 👉 doi.org/10.1093/ehjc... #CardioSky @jgrapsa.bsky.social
#EHJIMP 🫀 Is anterior mitral valve leaflet length linked to response to mavacamten in HCM? 📐 Shorter length ➡️ Lower dose & Faster response🔬 Could this be a new treatment predictor? 📚 Read more 👉 doi.org/10.1093/ehji... #CardioSky @jgrapsa.bsky.social @escardio.bsky.social
June 14, 2025 at 9:08 PM
#EHJIMP 🫀 Is anterior mitral valve leaflet length linked to response to mavacamten in HCM? 📐 Shorter length ➡️ Lower dose & Faster response🔬 Could this be a new treatment predictor? 📚 Read more 👉 doi.org/10.1093/ehji... #CardioSky @jgrapsa.bsky.social @escardio.bsky.social
#EHJCVI 📊 What’s the prognostic utility of CAC vs CCTA metrics in suspected CAD?💡Models including % atheroma vol outperform CAC in prediction 🧱 Non-calcified plaque % shows the highest accuracy for MI 📉 CAC alone may underestimate risk 🔗 Read more 👉 doi.org/10.1093/ehjc... #CardioSky
June 14, 2025 at 8:57 PM
#EHJCVI 📊 What’s the prognostic utility of CAC vs CCTA metrics in suspected CAD?💡Models including % atheroma vol outperform CAC in prediction 🧱 Non-calcified plaque % shows the highest accuracy for MI 📉 CAC alone may underestimate risk 🔗 Read more 👉 doi.org/10.1093/ehjc... #CardioSky