Periklis Paganos
@perievodevo.bsky.social
Animal evolution from a cell type perspective, evolution of organogenesis, gene regulatory networks in evolution and development, echinoderms
Pinned
I am beyond excited to share that my postdoc project @szndohrn.bsky.social and the @arnonelab.bsky.social is now available in #ScienceAdvances @science.org. www.science.org/doi/10.1126/...
Reposted by Periklis Paganos
New findings on genomic regulation mechanisms throughout evolution | EurekAlert! www.eurekalert.org/news-release...
New findings on genomic regulation mechanisms throughout evolution
The conservation of genome regulatory elements over long periods of evolution is not limited to vertebrates, as previously thought, but also in echinoderms (invertebrates). This is one of the most not...
www.eurekalert.org
January 15, 2026 at 9:39 AM
New findings on genomic regulation mechanisms throughout evolution | EurekAlert! www.eurekalert.org/news-release...
Reposted by Periklis Paganos
Thrilled to share that I’ve been awarded a FIS-3 Advanced Grant (ERC-inspired) to study the evolution of neurogenic GRNs.
Recruiting soon: 4 postdocs + 3 PhDs
Press release in Italian — to decolonise scientific language 😄
magazine.unibo.it/it/articoli/...
Email me if interested in joining the lab
Recruiting soon: 4 postdocs + 3 PhDs
Press release in Italian — to decolonise scientific language 😄
magazine.unibo.it/it/articoli/...
Email me if interested in joining the lab
Un viaggio all’origine dei sistemi nervosi
Il nuovo progetto GRNevo, finanziato con un grant FIS-3 Advanced da 1,9 milioni di euro, studierà come si formano i neuroni durante lo sviluppo in specie animali molto distanti tra loro: dal moscerino...
magazine.unibo.it
January 13, 2026 at 11:14 AM
Thrilled to share that I’ve been awarded a FIS-3 Advanced Grant (ERC-inspired) to study the evolution of neurogenic GRNs.
Recruiting soon: 4 postdocs + 3 PhDs
Press release in Italian — to decolonise scientific language 😄
magazine.unibo.it/it/articoli/...
Email me if interested in joining the lab
Recruiting soon: 4 postdocs + 3 PhDs
Press release in Italian — to decolonise scientific language 😄
magazine.unibo.it/it/articoli/...
Email me if interested in joining the lab
Coolness alert!! If you didn’t attend this fantastic microscopy course last year, make sure you do so this coming April! Don’t miss the chance to learn from the best in the field. Plus, the course takes place at @szndohrn.bsky.social, one of the most iconic marine stations in the world!
EMHOC’s preliminary program is out. Check it out to stay updated!
EMHOC 2026 preliminary program
EMHOC 2026 Preliminary Program Day 1 - Wednesday, April 8th 13h00 - 14h00 Arrival and registration 14h00 - 14h15 Welcome and introduction to the course Giovanna Benvenuto, Stazione Zoologica Napoli, ...
docs.google.com
January 12, 2026 at 11:25 AM
Coolness alert!! If you didn’t attend this fantastic microscopy course last year, make sure you do so this coming April! Don’t miss the chance to learn from the best in the field. Plus, the course takes place at @szndohrn.bsky.social, one of the most iconic marine stations in the world!
Reposted by Periklis Paganos
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
Evolutionary dynamics of temporal transcription factor series in the insect optic lobe https://www.biorxiv.org/content/10.64898/2026.01.08.698497v1
January 10, 2026 at 9:43 AM
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
Reposted by Periklis Paganos
Our work on the evolution of the regulatory genome of echinoderms is now out in @natecoevo.nature.com. Led by my former PhD Marta Magri, Danila Voronov & Saoirse Foley. Great collaboration of Arnone, Hinman & Maeso labs, started long time ago with our missed José Luis Gomez-Skarmeta: rdcu.be/eXX8l
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
Nature Ecology & Evolution - Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms...
rdcu.be
January 7, 2026 at 7:33 PM
Our work on the evolution of the regulatory genome of echinoderms is now out in @natecoevo.nature.com. Led by my former PhD Marta Magri, Danila Voronov & Saoirse Foley. Great collaboration of Arnone, Hinman & Maeso labs, started long time ago with our missed José Luis Gomez-Skarmeta: rdcu.be/eXX8l
Reposted by Periklis Paganos
Congratulations to the all team for this amazing work understanding how the cis regulatory elements and chromatin organization are relevant in the ancestral regulatory features of animal genomes.
This study started with a collaboration with José Luís Gómez Skarmeta from #CABD.
This study started with a collaboration with José Luís Gómez Skarmeta from #CABD.
Exciting news to start the new year! We’re thrilled to see this work finally out in @natecoevo.nature.com, the result of a major collaboration between my lab and the labs of Veronica Hinman and Nacho Maeso, began many years ago with the dear José Luis Gómez-Skarmeta.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 7, 2026 at 11:57 AM
Congratulations to the all team for this amazing work understanding how the cis regulatory elements and chromatin organization are relevant in the ancestral regulatory features of animal genomes.
This study started with a collaboration with José Luís Gómez Skarmeta from #CABD.
This study started with a collaboration with José Luís Gómez Skarmeta from #CABD.
Reposted by Periklis Paganos
I am extremely proud and happy to announce that another paper from my PhD days has just been published in @natecoevo.nature.com on evolution of genome and gene regulation thanks to all the amazing people involved.
Check the paper out at:
www.nature.com/articles/s41...
Check the paper out at:
www.nature.com/articles/s41...
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes - Nature Ecology & Evolution
Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms and the long-term evolutionary dynam...
www.nature.com
January 7, 2026 at 12:08 PM
I am extremely proud and happy to announce that another paper from my PhD days has just been published in @natecoevo.nature.com on evolution of genome and gene regulation thanks to all the amazing people involved.
Check the paper out at:
www.nature.com/articles/s41...
Check the paper out at:
www.nature.com/articles/s41...
Extremely happy to see this work out! I am deeply grateful to everyone who contributed, and especially to @danivoronov.bsky.social, who took the lead! @arnonelab.bsky.social sky is the limit! 🌊🔬🧬
Exciting news to start the new year! We’re thrilled to see this work finally out in @natecoevo.nature.com, the result of a major collaboration between my lab and the labs of Veronica Hinman and Nacho Maeso, began many years ago with the dear José Luis Gómez-Skarmeta.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 7, 2026 at 10:28 AM
Extremely happy to see this work out! I am deeply grateful to everyone who contributed, and especially to @danivoronov.bsky.social, who took the lead! @arnonelab.bsky.social sky is the limit! 🌊🔬🧬
When you combine a brilliant scientist with strong grant support, the result is magic. This is exactly what the NEF project will deliver, nothing less!
I am deeply honored to share that my project NeurEvoFun has been awarded support from the Fondo Italiano per la Scienza (FIS), the Advanced Grant by the Italian Ministry of Education, Universities and Research, supporting fundamental research inspired by the ERC model. Excited for what’s ahead!
January 3, 2026 at 10:34 AM
When you combine a brilliant scientist with strong grant support, the result is magic. This is exactly what the NEF project will deliver, nothing less!
Reposted by Periklis Paganos
First #MicroscopeMonday contribution!
Early auricularia larva of Holothuria tubulosa (4 days post-fertilisation, dpf) shown in brightfield (left) and with DAPI-stained nuclei (right, blue). Same larva. Same view.
Bonus: this was also my first DAPI stain, imaged on an inverted microscope.
Early auricularia larva of Holothuria tubulosa (4 days post-fertilisation, dpf) shown in brightfield (left) and with DAPI-stained nuclei (right, blue). Same larva. Same view.
Bonus: this was also my first DAPI stain, imaged on an inverted microscope.
December 1, 2025 at 9:21 PM
First #MicroscopeMonday contribution!
Early auricularia larva of Holothuria tubulosa (4 days post-fertilisation, dpf) shown in brightfield (left) and with DAPI-stained nuclei (right, blue). Same larva. Same view.
Bonus: this was also my first DAPI stain, imaged on an inverted microscope.
Early auricularia larva of Holothuria tubulosa (4 days post-fertilisation, dpf) shown in brightfield (left) and with DAPI-stained nuclei (right, blue). Same larva. Same view.
Bonus: this was also my first DAPI stain, imaged on an inverted microscope.
Reposted by Periklis Paganos
Researchers discover an "all-body brain" in sea urchins - @mfnberlin.bsky.social
www.museumfuernaturkunde.berlin/en/museum/me...
www.museumfuernaturkunde.berlin/en/museum/me...
Researchers discover an “all-body brain” in sea urchins
An international team of researchers, including scientists from the Museum für Naturkunde Berlin, has uncovered a surprisingly complex nervous system in sea urchins. The animals appear to possess an “...
www.museumfuernaturkunde.berlin
November 6, 2025 at 1:06 AM
Researchers discover an "all-body brain" in sea urchins - @mfnberlin.bsky.social
www.museumfuernaturkunde.berlin/en/museum/me...
www.museumfuernaturkunde.berlin/en/museum/me...
Reposted by Periklis Paganos
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Single-nucleus profiling highlights the all-brain echinoderm nervous system
A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
www.science.org
November 5, 2025 at 7:03 PM
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
I am beyond excited to share that my postdoc project @szndohrn.bsky.social and the @arnonelab.bsky.social is now available in #ScienceAdvances @science.org. www.science.org/doi/10.1126/...
November 5, 2025 at 7:02 PM
I am beyond excited to share that my postdoc project @szndohrn.bsky.social and the @arnonelab.bsky.social is now available in #ScienceAdvances @science.org. www.science.org/doi/10.1126/...
Thrilled to share my newest perspective article with @arnonelab.bsky.social in @dev-journal.bsky.social
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
In preprints: cell type-specific gene regulation through the lens of echinoderms
One of the most intriguing questions in developmental biology is how a single cell, the zygote, gives rise to hundreds or millions of distinct cell types during embryogenesis. Decades of research have...
journals.biologists.com
November 3, 2025 at 3:02 PM
Thrilled to share my newest perspective article with @arnonelab.bsky.social in @dev-journal.bsky.social
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Reposted by Periklis Paganos
Our lab studies how animals regenerate their body, e.g. how crustaceans regenerate broken legs. One of our aims is to understand if regeneration re-uses the gene networks that built the legs in the first place. Arthur Monternier, an artist in our team, captured the question in this cartoon.
October 27, 2025 at 3:25 PM
Our lab studies how animals regenerate their body, e.g. how crustaceans regenerate broken legs. One of our aims is to understand if regeneration re-uses the gene networks that built the legs in the first place. Arthur Monternier, an artist in our team, captured the question in this cartoon.
Reposted by Periklis Paganos
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Reposted by Periklis Paganos
📣 II Edition of the International Summer School “The Systems Biology Approach to Discover Marine Life: From a Big Eye to a Microscopic Picture”
📍 Stazione Zoologica Anton Dohrn / Darwin-Dohrn Museum, Naples (Italy)
🗓️ 27–30 October 2025
isssb2022.wixsite.com/isssystemsbi...
📍 Stazione Zoologica Anton Dohrn / Darwin-Dohrn Museum, Naples (Italy)
🗓️ 27–30 October 2025
isssb2022.wixsite.com/isssystemsbi...
June 26, 2025 at 9:04 AM
📣 II Edition of the International Summer School “The Systems Biology Approach to Discover Marine Life: From a Big Eye to a Microscopic Picture”
📍 Stazione Zoologica Anton Dohrn / Darwin-Dohrn Museum, Naples (Italy)
🗓️ 27–30 October 2025
isssb2022.wixsite.com/isssystemsbi...
📍 Stazione Zoologica Anton Dohrn / Darwin-Dohrn Museum, Naples (Italy)
🗓️ 27–30 October 2025
isssb2022.wixsite.com/isssystemsbi...
🤩
Our brittle star patterning study is now out at EvoDevo! 🥳
doi.org/10.1186/s132...
@lowelab.bsky.social
doi.org/10.1186/s132...
@lowelab.bsky.social
June 6, 2025 at 2:45 PM
🤩
Reposted by Periklis Paganos
Excited to welcome @mariacocurullo.bsky.social to the Tessmar-Raible lab, who secured a prestigious #MSCA Postdoctoral fellowship to explore how monthly timing shapes brain #plasticity in Platynereis dumerilii — and how light pollution at night may disrupt it.
#BrightPlaty #Platynereis #ALAN
#BrightPlaty #Platynereis #ALAN
May 27, 2025 at 3:40 PM
Excited to welcome @mariacocurullo.bsky.social to the Tessmar-Raible lab, who secured a prestigious #MSCA Postdoctoral fellowship to explore how monthly timing shapes brain #plasticity in Platynereis dumerilii — and how light pollution at night may disrupt it.
#BrightPlaty #Platynereis #ALAN
#BrightPlaty #Platynereis #ALAN
Reposted by Periklis Paganos
Job Alert! We are recruiting one postdoc to work on spiralian embryos and their crazy polar lobes. More info about this HFSP-funded position on our website baronelab.org: scroll to the end, click on "this could be you"...start your adventure!
May 28, 2025 at 2:48 AM
Job Alert! We are recruiting one postdoc to work on spiralian embryos and their crazy polar lobes. More info about this HFSP-funded position on our website baronelab.org: scroll to the end, click on "this could be you"...start your adventure!
Reposted by Periklis Paganos
Less than a week left to register and submit an abstract ‼️
Come & join us!
Come & join us!
May 27, 2025 at 8:08 PM
Less than a week left to register and submit an abstract ‼️
Come & join us!
Come & join us!
Reposted by Periklis Paganos
Interested in Developmental biology? Imaging? Marine invertebrate body plans? Then this three year postdoc in my group @sotonbiosciences.bsky.social is for you! Join our team to decypher how signalling molecules shape skeletal phenotype in juvenile sea urchins. jobs.soton.ac.uk/Vacancy.aspx...
May 12, 2025 at 11:00 AM
Interested in Developmental biology? Imaging? Marine invertebrate body plans? Then this three year postdoc in my group @sotonbiosciences.bsky.social is for you! Join our team to decypher how signalling molecules shape skeletal phenotype in juvenile sea urchins. jobs.soton.ac.uk/Vacancy.aspx...
Guys another fantastic opportunity, in a fantastic environment, wonderful PI and with one of the most promising new experimental systems!!Apply NOW!
Do you want to unravel the function of fluorescent cells in marine organisms?
Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers!
To apply: www.szn.it/.../ph-d-pro...
Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers!
To apply: www.szn.it/.../ph-d-pro...
May 23, 2025 at 4:42 PM
Guys another fantastic opportunity, in a fantastic environment, wonderful PI and with one of the most promising new experimental systems!!Apply NOW!
Don’t hesitate!!! Amazing project and team and fantastic mentor!!! Apply NOW!
Do you want to understand how developmental programs are encoded in animal genomes? Join our lab at the @szndohrn.bsky.social for a PhD project to unravel the developmental dynamics in sea urchins during the metamorphosis from larva to juvenile.
Deadline JUNE 14th!
www.szn.it/index.php/it...
Deadline JUNE 14th!
www.szn.it/index.php/it...
May 21, 2025 at 6:56 PM
Don’t hesitate!!! Amazing project and team and fantastic mentor!!! Apply NOW!
Reposted by Periklis Paganos
Single Nucleus Profiling Highlights the All-Brain Echinoderm Nervous System https://www.biorxiv.org/content/10.1101/2025.03.24.644250v1
March 28, 2025 at 1:34 PM
Single Nucleus Profiling Highlights the All-Brain Echinoderm Nervous System https://www.biorxiv.org/content/10.1101/2025.03.24.644250v1