Aline Petrin
@petrinlab.bsky.social
Assistant Professor, UIowa, scientist, mom, writer, #Genetics #Epigenetics #orofacialclefts #DNAmethylation #cleftlipandpalate #twinsresearch #Hawkeye 🧬🔬🧫
Pinned
Aline Petrin
@petrinlab.bsky.social
· Jun 25
Another Hatton Award for Iowa! Congratulations, Saba Manafi for winning 2nd place Junior Category! It is so rewarding to see your hard work recognized. #proudmentor 🎉 ❤️ #IADR2025 #uiowadentistry #uiowaresearch #cleftlipandpalate #womeninscience #oavs #PetrinLab
Ready for the 73rd Iowa Section of the AADOCR. Come see our work on Genomics and Epigenomics of Orofacial Clefts and Van der Woude Syndrome. #uiowadentistry #uiowaresearch #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience
February 5, 2026 at 4:59 PM
Ready for the 73rd Iowa Section of the AADOCR. Come see our work on Genomics and Epigenomics of Orofacial Clefts and Van der Woude Syndrome. #uiowadentistry #uiowaresearch #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience
Our latest research is now available on MedRxiv. We examined laterality and completeness patterns in nonsyndromic cleft lip with or without cleft palate (NSCL/P) across a multiethnic cohort. #uiowaresearch #laterality #cleftresearch #uiowadentistry
www.medrxiv.org/content/10.6...
www.medrxiv.org/content/10.6...
Laterality and Completeness Patterns of Nonsyndromic Clefts in a Multiethnic Cohort
Objective: Orofacial clefts may involve the complete vertical thickness of the lip (complete) or partial thickness (incomplete). This study evaluates side preference for completeness in nonsyndromic a...
www.medrxiv.org
December 30, 2025 at 2:33 AM
Our latest research is now available on MedRxiv. We examined laterality and completeness patterns in nonsyndromic cleft lip with or without cleft palate (NSCL/P) across a multiethnic cohort. #uiowaresearch #laterality #cleftresearch #uiowadentistry
www.medrxiv.org/content/10.6...
www.medrxiv.org/content/10.6...
Reposted by Aline Petrin
Laterality and Completeness Patterns of Nonsyndromic Clefts in a Multiethnic Cohort https://www.medrxiv.org/content/10.64898/2025.12.29.25343144v1
December 30, 2025 at 12:40 AM
Laterality and Completeness Patterns of Nonsyndromic Clefts in a Multiethnic Cohort https://www.medrxiv.org/content/10.64898/2025.12.29.25343144v1
Grateful for the continued support to our research program! 🙏 🧬 🔬 #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics
dentistry.uiowa.edu/news/2025/09...
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics
dentistry.uiowa.edu/news/2025/09...
CRISP grant supports study of genetic variation in Van der Woude syndrome
Aline Petrin, assistant professor of orthodontics, received a CRISP grant to complete genetic screening of patients with Van der Woude syndrome. Her study will help clarify how genetic mutations influ...
dentistry.uiowa.edu
October 3, 2025 at 4:16 PM
Grateful for the continued support to our research program! 🙏 🧬 🔬 #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics
dentistry.uiowa.edu/news/2025/09...
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics
dentistry.uiowa.edu/news/2025/09...
Kicking off two days of learning and scientific networking at the University of Minnesota. Come see poster 31 to learn more about our work on Methylation Quantitative Traits and Orofacial Clefts #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #scgdb2025
September 30, 2025 at 4:06 PM
Kicking off two days of learning and scientific networking at the University of Minnesota. Come see poster 31 to learn more about our work on Methylation Quantitative Traits and Orofacial Clefts #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #scgdb2025
Another Hatton Award for Iowa! Congratulations, Saba Manafi for winning 2nd place Junior Category! It is so rewarding to see your hard work recognized. #proudmentor 🎉 ❤️ #IADR2025 #uiowadentistry #uiowaresearch #cleftlipandpalate #womeninscience #oavs #PetrinLab
June 25, 2025 at 6:29 PM
Another Hatton Award for Iowa! Congratulations, Saba Manafi for winning 2nd place Junior Category! It is so rewarding to see your hard work recognized. #proudmentor 🎉 ❤️ #IADR2025 #uiowadentistry #uiowaresearch #cleftlipandpalate #womeninscience #oavs #PetrinLab
Wrapping the #AADOCR2025 meeting in NYC. What an amazing week of learning, networking and reconnecting with friends! #uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #craniofacial #twinstudies #oavs #aadocr2025 🧬 🦷 🔬 🗽
March 15, 2025 at 7:06 PM
Wrapping the #AADOCR2025 meeting in NYC. What an amazing week of learning, networking and reconnecting with friends! #uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #craniofacial #twinstudies #oavs #aadocr2025 🧬 🦷 🔬 🗽
Another successful day for the Petrin Lab at #AADOCR2025. Great presentations by these bright young scientists. Thank you for your dedication representing our work!
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬
March 13, 2025 at 6:59 PM
Another successful day for the Petrin Lab at #AADOCR2025. Great presentations by these bright young scientists. Thank you for your dedication representing our work!
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬
#Proudmentor moment! Super congratulations to this amazing young scientist for all her hard work on this project and for winning second place in the #AADOCR2025 Hatton Competition! Next stop - Barcelona 🇪🇸 #IADR2025
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs
March 13, 2025 at 12:29 PM
#Proudmentor moment! Super congratulations to this amazing young scientist for all her hard work on this project and for winning second place in the #AADOCR2025 Hatton Competition! Next stop - Barcelona 🇪🇸 #IADR2025
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs
10 days until the #AADOCR2025 in New York City. Come visit our posters and hear from these amazing students about their work on genetic and epigenetics of orofacial clefts. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #genetics #twinstudies #nidcr #aadocr2025
March 2, 2025 at 10:45 PM
10 days until the #AADOCR2025 in New York City. Come visit our posters and hear from these amazing students about their work on genetic and epigenetics of orofacial clefts. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #genetics #twinstudies #nidcr #aadocr2025
The College of Dentistry’s, Iowa Institute for Oral Health and Research is seeking a Biostatistician to collaborate with investigators, driving impactful studies, analyzing complex data, and crafting reports for grants and publications – apply today!
phxc3c.rfer.us/UIOWA7njOWH
phxc3c.rfer.us/UIOWA7njOWH
Biostatistician - Iowa Institute for Oral Health in Iowa City, Iowa, United States
The College of Dentistry’s, Iowa Institute for Oral Health and Research is seeking a Biostatistician. In this role, you’ll collaborate...
phxc3c.rfer.us
February 16, 2025 at 5:46 PM
The College of Dentistry’s, Iowa Institute for Oral Health and Research is seeking a Biostatistician to collaborate with investigators, driving impactful studies, analyzing complex data, and crafting reports for grants and publications – apply today!
phxc3c.rfer.us/UIOWA7njOWH
phxc3c.rfer.us/UIOWA7njOWH
Reposted by Aline Petrin
Methylation quantitative loci analysis in nonsyndromic orofacial clefts https://www.medrxiv.org/content/10.1101/2025.02.09.25321494v1
February 12, 2025 at 8:40 PM
Methylation quantitative loci analysis in nonsyndromic orofacial clefts https://www.medrxiv.org/content/10.1101/2025.02.09.25321494v1
New preprint from the Petrin Lab: doi.org/10.1101/2025...
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl
Methylation quantitative loci analysis in nonsyndromic orofacial clefts
Objectives: Nonsyndromic orofacial clefts (OFCs) etiology involves multiple genetic and environmental factors with over 60 identified risk loci; however, they account for a minority of the estimated r...
doi.org
February 12, 2025 at 10:31 PM
New preprint from the Petrin Lab: doi.org/10.1101/2025...
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl
OAVS is caused by abnormalities of the first and second pharyngeal arches during embryogenesis and requires many corrective surgeries. Check our new paper on the genomics of a familial case with autosomal dominant inheritance #PetrinLab #OAVS #cleft #microsomia
journals.sagepub.com/doi/epub/10....
journals.sagepub.com/doi/epub/10....
January 17, 2025 at 5:26 PM
OAVS is caused by abnormalities of the first and second pharyngeal arches during embryogenesis and requires many corrective surgeries. Check our new paper on the genomics of a familial case with autosomal dominant inheritance #PetrinLab #OAVS #cleft #microsomia
journals.sagepub.com/doi/epub/10....
journals.sagepub.com/doi/epub/10....
Reposted by Aline Petrin
Reposted by Aline Petrin
Whole genome sequencing of a family with autosomal dominant features within the oculoauriculovertebral spectrum https://www.medrxiv.org/content/10.1101/2024.02.07.24301824v1
Whole genome sequencing of a family with autosomal dominant features within the oculoauriculovertebral spectrum https://www.medrxiv.org/content/10.1101/2024.02.07.24301824v1
Background: Oculoauriculovertebral Spectrum (OAVS) encompasses a wide variety of anomalies derived f
www.medrxiv.org
February 7, 2024 at 8:40 PM
Whole genome sequencing of a family with autosomal dominant features within the oculoauriculovertebral spectrum https://www.medrxiv.org/content/10.1101/2024.02.07.24301824v1
Check out our new paper on DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #vanderwoudesyndrome #lipits #uicod #womeninscience #proudmentor #nidcr #PetrinLab
doi.org/10.1177/1055...
doi.org/10.1177/1055...
DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability - Amanda Seaberg, Waheed Awotoye, Fang Qian, Ligiane A. Machado-Paula, Lindsey Dunlay, Azeez Butali, Jeff Murray, Lina Moreno-...
Objective Van der Woude Syndrome (VWS) presents with combinations of lip pits (LP) and cleft lip and/or cleft palate (CL/P, CPO). VWS phenotypic heterogeneity e...
doi.org
December 10, 2024 at 2:53 AM
Check out our new paper on DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #vanderwoudesyndrome #lipits #uicod #womeninscience #proudmentor #nidcr #PetrinLab
doi.org/10.1177/1055...
doi.org/10.1177/1055...
New preprint: Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57. #uiowadentistry #twinstudies #uicod #cleftlipandpalate #nidcr #Epigenetics
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57
Background Disturbances in the intricate processes that control craniofacial morphogenesis can result in birth defects, most common of which are orofacial clefts (OFCs). Nonsyndromic cleft lip (nsCL),...
www.medrxiv.org
December 10, 2024 at 2:52 AM
New preprint: Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57. #uiowadentistry #twinstudies #uicod #cleftlipandpalate #nidcr #Epigenetics
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...