Phage papers
@phagepapers.bsky.social
Bsky bot that delivers new phage related papers and news! Tweets are not endorsements! Started by
@jamesgurney.bsky.social and saved by @yawnxyz.bsky.social
@jamesgurney.bsky.social and saved by @yawnxyz.bsky.social
Transmission mechanisms and risk tracing of antibiotic resistance genes in rivers driven by wastewater inputs.
DOI: 10.1016/j.jhazmat.2025.140523
https://pubmed.ncbi.nlm.nih.gov/41259914/
DOI: 10.1016/j.jhazmat.2025.140523
https://pubmed.ncbi.nlm.nih.gov/41259914/
Transmission mechanisms and risk tracing of antibiotic resistance genes in rivers driven by wastewater inputs - PubMed
Aquatic environments are critical for ARG dissemination, yet contributions from different wastewater sources, dominant HGT mechanisms, and residual risks in natural waters remain unclear. Based on 863 metagenomic samples across China, we systematically analyzed wastewater inputs, HGT mechanisms, and …
pubmed.ncbi.nlm.nih.gov
November 25, 2025 at 11:53 AM
Transmission mechanisms and risk tracing of antibiotic resistance genes in rivers driven by wastewater inputs.
DOI: 10.1016/j.jhazmat.2025.140523
https://pubmed.ncbi.nlm.nih.gov/41259914/
DOI: 10.1016/j.jhazmat.2025.140523
https://pubmed.ncbi.nlm.nih.gov/41259914/
Technological advancements in antibody-based therapeutics for treatment of diseases.
DOI: 10.1186/s12929-025-01190-2
https://pubmed.ncbi.nlm.nih.gov/41219972/
DOI: 10.1186/s12929-025-01190-2
https://pubmed.ncbi.nlm.nih.gov/41219972/
Technological advancements in antibody-based therapeutics for treatment of diseases - PubMed
Monoclonal antibodies (mAbs) represent a major class of therapeutics with widespread clinical applications in oncology, immunology, hematology, neurology and infectious disease. Since the introduction of hybridoma technology in 1975, the field has been advanced by a succession of innovations includi …
pubmed.ncbi.nlm.nih.gov
November 25, 2025 at 7:53 AM
Technological advancements in antibody-based therapeutics for treatment of diseases.
DOI: 10.1186/s12929-025-01190-2
https://pubmed.ncbi.nlm.nih.gov/41219972/
DOI: 10.1186/s12929-025-01190-2
https://pubmed.ncbi.nlm.nih.gov/41219972/
The infectome framework: linking polymicrobial ecology and biofilm dynamics to precision diagnostic approaches.
DOI: 10.1007/s15010-025-02687-6
https://pubmed.ncbi.nlm.nih.gov/41201733/
DOI: 10.1007/s15010-025-02687-6
https://pubmed.ncbi.nlm.nih.gov/41201733/
The infectome framework: linking polymicrobial ecology and biofilm dynamics to precision diagnostic approaches - PubMed
Chronic infections are a persistent global health problem and are frequently sustained by polymicrobial communities rather than by a single pathogen. This review brings together current evidence for the infectome concept, defined as the dynamic set of pathogenic or pathobiont taxa in the host, their …
pubmed.ncbi.nlm.nih.gov
November 25, 2025 at 3:53 AM
The infectome framework: linking polymicrobial ecology and biofilm dynamics to precision diagnostic approaches.
DOI: 10.1007/s15010-025-02687-6
https://pubmed.ncbi.nlm.nih.gov/41201733/
DOI: 10.1007/s15010-025-02687-6
https://pubmed.ncbi.nlm.nih.gov/41201733/
Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention.
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention - PubMed
This case underscores the potential of phage therapy to complement traditional treatments in managing chronic bacterial infections in CF patients, though further studies are needed to optimize treatment protocols and understand the role of phages in modulating the bacterial population.
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 11:53 PM
Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention.
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
Harnessing droplet microfluidics and morphology-based deep learning for the label-free study of polymicrobial-phage interactions.
DOI: 10.1038/s42003-025-08925-9
https://pubmed.ncbi.nlm.nih.gov/41225150/
DOI: 10.1038/s42003-025-08925-9
https://pubmed.ncbi.nlm.nih.gov/41225150/
Harnessing droplet microfluidics and morphology-based deep learning for the label-free study of polymicrobial-phage interactions - PubMed
Evaluating the impact of bacteriophages on bacterial communities is required to assess the future utility of phage therapy. Methods able to study bacterial polycultures in the presence of phages are useful to mimic evolutionary pressures found in natural environments and recapitulate complex ecologi …
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 7:52 PM
Harnessing droplet microfluidics and morphology-based deep learning for the label-free study of polymicrobial-phage interactions.
DOI: 10.1038/s42003-025-08925-9
https://pubmed.ncbi.nlm.nih.gov/41225150/
DOI: 10.1038/s42003-025-08925-9
https://pubmed.ncbi.nlm.nih.gov/41225150/
Bathing seawater and sand as reservoirs of clinically relevant and antimicrobial resistant Klebsiella pneumoniae strains.
DOI: 10.1016/j.scitotenv.2025.180930
https://pubmed.ncbi.nlm.nih.gov/41237617/
DOI: 10.1016/j.scitotenv.2025.180930
https://pubmed.ncbi.nlm.nih.gov/41237617/
Bathing seawater and sand as reservoirs of clinically relevant and antimicrobial resistant Klebsiella pneumoniae strains - PubMed
Klebsiella pneumoniae is included in the ESKAPE list of bacteria, which are currently considered the greatest threat to human health. It is widely distributed in the environment, including waters, soils, and plants. According to the One Health concept, it is essential to enhance our understanding of …
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 3:52 PM
Bathing seawater and sand as reservoirs of clinically relevant and antimicrobial resistant Klebsiella pneumoniae strains.
DOI: 10.1016/j.scitotenv.2025.180930
https://pubmed.ncbi.nlm.nih.gov/41237617/
DOI: 10.1016/j.scitotenv.2025.180930
https://pubmed.ncbi.nlm.nih.gov/41237617/
Disarming Salmonella virulence with 32H-hilE anti-virulence bacteriophage.
DOI: 10.1016/j.micres.2025.128396
https://pubmed.ncbi.nlm.nih.gov/41240734/
DOI: 10.1016/j.micres.2025.128396
https://pubmed.ncbi.nlm.nih.gov/41240734/
Disarming Salmonella virulence with 32H-hilE anti-virulence bacteriophage - PubMed
As the development of new antibiotics struggles with the continuous emergence of drug-resistant bacteria, targeting bacterial virulence factors instead of viability has been proposed as one of the alternative approaches to combat the pathogens. Here, we genetically engineered the temperate phage SPC …
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 11:52 AM
Disarming Salmonella virulence with 32H-hilE anti-virulence bacteriophage.
DOI: 10.1016/j.micres.2025.128396
https://pubmed.ncbi.nlm.nih.gov/41240734/
DOI: 10.1016/j.micres.2025.128396
https://pubmed.ncbi.nlm.nih.gov/41240734/
Identification of internalizing ScFvs for EGFR inhibition and apoptosis induction in cholangiocarcinoma cells.
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
Identification of internalizing ScFvs for EGFR inhibition and apoptosis induction in cholangiocarcinoma cells - PubMed
Cholangiocarcinoma (CCA) is an aggressive malignancy with limited treatment options. EGFR overexpression is associated with tumor recurrence and poor prognosis, yet current EGFR-targeted therapies show limited efficacy. To identify alternative therapeutic candidates, we performed subtractive bio-pan …
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 7:51 AM
Identification of internalizing ScFvs for EGFR inhibition and apoptosis induction in cholangiocarcinoma cells.
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
Exploring diversity and distribution patterns of chicken gut bacteriophage community.
DOI: 10.1186/s42523-025-00484-y
https://pubmed.ncbi.nlm.nih.gov/41239428/
DOI: 10.1186/s42523-025-00484-y
https://pubmed.ncbi.nlm.nih.gov/41239428/
Exploring diversity and distribution patterns of chicken gut bacteriophage community - PubMed
The online version contains supplementary material available at 10.1186/s42523-025-00484-y.
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 3:51 AM
Exploring diversity and distribution patterns of chicken gut bacteriophage community.
DOI: 10.1186/s42523-025-00484-y
https://pubmed.ncbi.nlm.nih.gov/41239428/
DOI: 10.1186/s42523-025-00484-y
https://pubmed.ncbi.nlm.nih.gov/41239428/
Complete genome sequence of lytic Pseudomonas aeruginosa phage vB_PaeS_Tums_P6.
DOI: 10.1007/s13205-025-04528-7
https://pubmed.ncbi.nlm.nih.gov/41255842/
DOI: 10.1007/s13205-025-04528-7
https://pubmed.ncbi.nlm.nih.gov/41255842/
Complete genome sequence of lytic Pseudomonas aeruginosa phage vB_PaeS_Tums_P6 - PubMed
The online version contains supplementary material available at 10.1007/s13205-025-04528-7.
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 11:51 PM
Complete genome sequence of lytic Pseudomonas aeruginosa phage vB_PaeS_Tums_P6.
DOI: 10.1007/s13205-025-04528-7
https://pubmed.ncbi.nlm.nih.gov/41255842/
DOI: 10.1007/s13205-025-04528-7
https://pubmed.ncbi.nlm.nih.gov/41255842/
Conserved tripartite tail proteins mediate virophage-host interactions through Synechococcus lipopolysaccharide binding.
DOI: 10.1128/jvi.01082-25
https://pubmed.ncbi.nlm.nih.gov/41251349/
DOI: 10.1128/jvi.01082-25
https://pubmed.ncbi.nlm.nih.gov/41251349/
Conserved tripartite tail proteins mediate virophage-host interactions through Synechococcus lipopolysaccharide binding - PubMed
This study significantly advances our understanding of virophage biology by elucidating key molecular mechanisms underlying their host interactions. The discovery of a conserved heterotrimeric tail complex in Dishui Lake Virophage 2, evolutionarily related to tail proteins of <i>Synechococcus</i> ph …
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 7:51 PM
Conserved tripartite tail proteins mediate virophage-host interactions through Synechococcus lipopolysaccharide binding.
DOI: 10.1128/jvi.01082-25
https://pubmed.ncbi.nlm.nih.gov/41251349/
DOI: 10.1128/jvi.01082-25
https://pubmed.ncbi.nlm.nih.gov/41251349/
Identification of internalizing ScFvs for EGFR inhibition and apoptosis induction in cholangiocarcinoma cells.
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
Identification of internalizing ScFvs for EGFR inhibition and apoptosis induction in cholangiocarcinoma cells - PubMed
Cholangiocarcinoma (CCA) is an aggressive malignancy with limited treatment options. EGFR overexpression is associated with tumor recurrence and poor prognosis, yet current EGFR-targeted therapies show limited efficacy. To identify alternative therapeutic candidates, we performed subtractive bio-pan …
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 3:51 PM
Identification of internalizing ScFvs for EGFR inhibition and apoptosis induction in cholangiocarcinoma cells.
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
DOI: 10.1038/s41598-025-24324-w
https://pubmed.ncbi.nlm.nih.gov/41257876/
KlebPhaCol: a community-driven resource for Klebsiella research identified a novel phage family.
DOI: 10.1093/nar/gkaf1122
https://pubmed.ncbi.nlm.nih.gov/41261852/
DOI: 10.1093/nar/gkaf1122
https://pubmed.ncbi.nlm.nih.gov/41261852/
KlebPhaCol: a community-driven resource for Klebsiella research identified a novel phage family - PubMed
The growing threat of multidrug-resistant Klebsiella pneumoniae, coupled with its role in gut colonisation, has intensified the search for new treatments, including bacteriophage therapy. Despite increasing documentation of Klebsiella-targeting phages, clinical applications remain limited, with key …
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 11:50 AM
KlebPhaCol: a community-driven resource for Klebsiella research identified a novel phage family.
DOI: 10.1093/nar/gkaf1122
https://pubmed.ncbi.nlm.nih.gov/41261852/
DOI: 10.1093/nar/gkaf1122
https://pubmed.ncbi.nlm.nih.gov/41261852/
Genomic characterization of an Anticarsia gemmatalis multiple nucleopolyhedrovirus isolate from the cotton leafworm, Alabama argillacea with cross-species infectivity potential for pest management.
DOI: 10.1016/j.virol.2025.110740
https://pubmed.ncbi.nlm.nih.gov/41248595/
DOI: 10.1016/j.virol.2025.110740
https://pubmed.ncbi.nlm.nih.gov/41248595/
Genomic characterization of an Anticarsia gemmatalis multiple nucleopolyhedrovirus isolate from the cotton leafworm, Alabama argillacea with cross-species infectivity potential for pest management - PubMed
The cotton leafworm Alabama argillacea is an important pest of cotton in South America, traditionally controlled using chemical insecticides, which reinforces the demand for environmentally safe alternatives. Baculoviruses are widely used in microbial pest control due to their efficacy and biosafety …
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 7:50 AM
Genomic characterization of an Anticarsia gemmatalis multiple nucleopolyhedrovirus isolate from the cotton leafworm, Alabama argillacea with cross-species infectivity potential for pest management.
DOI: 10.1016/j.virol.2025.110740
https://pubmed.ncbi.nlm.nih.gov/41248595/
DOI: 10.1016/j.virol.2025.110740
https://pubmed.ncbi.nlm.nih.gov/41248595/
Antivirulence drugs against Acinetobacter baumannii: where do they stand?
DOI: 10.1007/s11274-025-04593-3
https://pubmed.ncbi.nlm.nih.gov/41165876/
DOI: 10.1007/s11274-025-04593-3
https://pubmed.ncbi.nlm.nih.gov/41165876/
Antivirulence drugs against Acinetobacter baumannii: where do they stand? - PubMed
Acinetobacter baumannii is a nosocomial Gram-negative pathogen of multi- and extensive-drug resistance phenotypes. In certain regions, multi-drug resistance rates can soar as high as 80-90%. Accordingly, reports by the World Health Organization and the Centers for Disease Control and Prevention unde …
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 3:50 AM
Antivirulence drugs against Acinetobacter baumannii: where do they stand?
DOI: 10.1007/s11274-025-04593-3
https://pubmed.ncbi.nlm.nih.gov/41165876/
DOI: 10.1007/s11274-025-04593-3
https://pubmed.ncbi.nlm.nih.gov/41165876/
Inactivating conditions of therapeutic mycobacteriophages.
DOI: 10.1101/2025.09.30.679648
https://pubmed.ncbi.nlm.nih.gov/41256447/
DOI: 10.1101/2025.09.30.679648
https://pubmed.ncbi.nlm.nih.gov/41256447/
Inactivating conditions of therapeutic mycobacteriophages - PubMed
There is a need for new therapies to treat drug resistant nontuberculous mycobacteria (NTM) disease. Bacteriophages (phages), which are viruses that infect and kill bacteria, are actively being explored as an alternative approach for treating mycobacterial diseases. Several compassionate-use cases o …
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 11:50 PM
Inactivating conditions of therapeutic mycobacteriophages.
DOI: 10.1101/2025.09.30.679648
https://pubmed.ncbi.nlm.nih.gov/41256447/
DOI: 10.1101/2025.09.30.679648
https://pubmed.ncbi.nlm.nih.gov/41256447/
Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention.
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention - PubMed
This case underscores the potential of phage therapy to complement traditional treatments in managing chronic bacterial infections in CF patients, though further studies are needed to optimize treatment protocols and understand the role of phages in modulating the bacterial population.
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 7:49 PM
Resolution of acute rejection in a bilateral double-lung transplanted cystic fibrosis patient following phage intervention.
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
DOI: 10.1128/asmcr.00058-24
https://pubmed.ncbi.nlm.nih.gov/41244966/
Isolation, Identification and Typing of Nine Strains of Brucella in Arun Banner.
DOI: 10.1002/vms3.70694
https://pubmed.ncbi.nlm.nih.gov/41251272/
DOI: 10.1002/vms3.70694
https://pubmed.ncbi.nlm.nih.gov/41251272/
Isolation, Identification and Typing of Nine Strains of Brucella in Arun Banner - PubMed
People involved in raising and trafficking sheep constitute a high-risk group for brucellosis. The strains isolated were B. melitensis, with ST8 as the predominant type identified by MLST typing. Attention should also be given to the discovery of new alleles.
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 3:49 PM
Isolation, Identification and Typing of Nine Strains of Brucella in Arun Banner.
DOI: 10.1002/vms3.70694
https://pubmed.ncbi.nlm.nih.gov/41251272/
DOI: 10.1002/vms3.70694
https://pubmed.ncbi.nlm.nih.gov/41251272/
Polyvalent phage GSP004 recognizes O-antigen polysaccharide receptors in Salmonella and Escherichia coli through tail fiber protein ORF208.
DOI: 10.1128/jvi.00810-25
https://pubmed.ncbi.nlm.nih.gov/41251352/
DOI: 10.1128/jvi.00810-25
https://pubmed.ncbi.nlm.nih.gov/41251352/
Polyvalent phage GSP004 recognizes O-antigen polysaccharide receptors in Salmonella and Escherichia coli through tail fiber protein ORF208 - PubMed
The majority of phages are capable of lysing only specific bacterial strains within a single species, and polyvalent phages with cross-genus lytic capability are relatively rare. In this study, we isolated a polyvalent phage, GSP004, from swine farm wastewater, which exhibited cross-genus lytic acti …
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 11:49 AM
Polyvalent phage GSP004 recognizes O-antigen polysaccharide receptors in Salmonella and Escherichia coli through tail fiber protein ORF208.
DOI: 10.1128/jvi.00810-25
https://pubmed.ncbi.nlm.nih.gov/41251352/
DOI: 10.1128/jvi.00810-25
https://pubmed.ncbi.nlm.nih.gov/41251352/
Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time.
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time - PubMed
Aortitis due to hypervirulent Klebsiella pneumoniae (hvKp) in a Belarusian male from central New York is described. Isolates at the time of diagnosis (Kp031824-1, Kp031824-2) and after 12 weeks of antimicrobial therapy (Kp070124) were characterized. Kp070124 was genomically and phenotypically unchan …
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 7:49 AM
Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time.
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
Bacteriophage density influences the rate of resistance evolution.
DOI: 10.1101/2025.10.05.680490
https://pubmed.ncbi.nlm.nih.gov/41256655/
DOI: 10.1101/2025.10.05.680490
https://pubmed.ncbi.nlm.nih.gov/41256655/
Bacteriophage density influences the rate of resistance evolution - PubMed
The antagonistic relationship between bacteria and bacteriophages (phages) drives genetic changes that result in phage resistance. Phage resistance mutations arise in natural microbial communities and during the treatment of diseases with phages (phage therapy), making it important to understand the …
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 3:49 AM
Bacteriophage density influences the rate of resistance evolution.
DOI: 10.1101/2025.10.05.680490
https://pubmed.ncbi.nlm.nih.gov/41256655/
DOI: 10.1101/2025.10.05.680490
https://pubmed.ncbi.nlm.nih.gov/41256655/
Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery.
DOI: 10.1073/pnas.2519643122
https://pubmed.ncbi.nlm.nih.gov/41252147/
DOI: 10.1073/pnas.2519643122
https://pubmed.ncbi.nlm.nih.gov/41252147/
Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery - PubMed
Bacterial immune systems exhibit remarkable diversity and modularity, as a consequence of the continuous selective pressures imposed by phage predation. Despite recent mechanistic advances, the evolutionary origins of many antiphage immune systems remain elusive, especially for those that encode hom …
pubmed.ncbi.nlm.nih.gov
November 21, 2025 at 11:48 PM
Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery.
DOI: 10.1073/pnas.2519643122
https://pubmed.ncbi.nlm.nih.gov/41252147/
DOI: 10.1073/pnas.2519643122
https://pubmed.ncbi.nlm.nih.gov/41252147/
A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade.
DOI: 10.1038/s41392-025-02457-8
https://pubmed.ncbi.nlm.nih.gov/41188260/
DOI: 10.1038/s41392-025-02457-8
https://pubmed.ncbi.nlm.nih.gov/41188260/
A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade - PubMed
Sepsis is a life-threatening syndrome characterized by dysregulated host responses to infection, leading to severe organ dysfunction and a high mortality rate. Reducing the incidence of sepsis is of paramount importance. Given that sepsis-associated drugs largely fail in clinical trials, in this pro …
pubmed.ncbi.nlm.nih.gov
November 21, 2025 at 7:48 PM
A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade.
DOI: 10.1038/s41392-025-02457-8
https://pubmed.ncbi.nlm.nih.gov/41188260/
DOI: 10.1038/s41392-025-02457-8
https://pubmed.ncbi.nlm.nih.gov/41188260/
Novel lytic phages improve the antibiofilm activity of dalbavancin, daptomycin, and fosfomycin against vancomycin-resistant enterococci.
DOI: 10.1128/spectrum.01818-25
https://pubmed.ncbi.nlm.nih.gov/41258817/
DOI: 10.1128/spectrum.01818-25
https://pubmed.ncbi.nlm.nih.gov/41258817/
Novel lytic phages improve the antibiofilm activity of dalbavancin, daptomycin, and fosfomycin against vancomycin-resistant enterococci - PubMed
Periprosthetic joint infections (PJI) caused by <i>Enterococcus</i> spp., especially vancomycin-resistant strains (VRE), are challenging to treat due to biofilm tolerance and limited antibiotic options. Bacteriophages offer a promising adjunct through targeted and biofilm-disrupting activity. This s …
pubmed.ncbi.nlm.nih.gov
November 21, 2025 at 3:48 PM
Novel lytic phages improve the antibiofilm activity of dalbavancin, daptomycin, and fosfomycin against vancomycin-resistant enterococci.
DOI: 10.1128/spectrum.01818-25
https://pubmed.ncbi.nlm.nih.gov/41258817/
DOI: 10.1128/spectrum.01818-25
https://pubmed.ncbi.nlm.nih.gov/41258817/
A previously undescribed archaeal virus suppresses host immunity.
DOI: 10.1038/s44319-025-00540-3
https://pubmed.ncbi.nlm.nih.gov/41249581/
DOI: 10.1038/s44319-025-00540-3
https://pubmed.ncbi.nlm.nih.gov/41249581/
A previously undescribed archaeal virus suppresses host immunity - PubMed
Extremophilic archaea can have chronic viral infections that are well-tolerated by the hosts and may potentially protect against more lethal infections. Here we show that a natural Haloferax strain (48N), is chronically infected by a lemon-shaped virus. This viral infection is not cleared spontaneou …
pubmed.ncbi.nlm.nih.gov
November 21, 2025 at 11:48 AM
A previously undescribed archaeal virus suppresses host immunity.
DOI: 10.1038/s44319-025-00540-3
https://pubmed.ncbi.nlm.nih.gov/41249581/
DOI: 10.1038/s44319-025-00540-3
https://pubmed.ncbi.nlm.nih.gov/41249581/