PLOS Medicine
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PLOS Medicine
@plosmedicine.org
Leading open access health science journal publishing impactful research that transforms global healthcare and advances clinical understanding.

🔗 https://journals.plos.org/plosmedicine
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We are thrilled to now be on BlueSky!

We prioritize studies addressing critical health challenges—from major diseases to health equity—that bridge scientific rigor with real-world impact, connecting researchers, clinicians, and policymakers to advance global health 🧬🧪

#OpenScience #MedSky
Next up in our "meet the editors", it's Editor-in-Chief of PLOS Medicine, Till Bärnighausen, Director of the Heidelberg Institute of Global Health and Alexander von Humboldt Professor at the University of Heidelberg. 🧪 #MedSky #PLOSMedicine
December 11, 2025 at 5:15 PM
In this retrospective analysis of national surveillance data in China, Li Chen & colleagues find that short-term exposure to wildfire-related fine particulate matter (PM2.5) was associated with a higher incidence of respiratory transmitted diseases than non-wildfire-related PM2.5.🧪
plos.io/4iRaPBn
Wildfire-related PM2.5 and respiratory transmitted disease among Chinese children and adolescents from 2008 to 2019: A retrospective study
In a retrospective analysis of national surveillance data in China over a 12 year period, Li Chen and colleagues find that short-term exposure to wildfire-related fine particulate matter (PM2.5) was a...
plos.io
December 11, 2025 at 10:22 AM
Analyses of open health datasets can offer valuable contributions to health & medicine, but recent years have seen a proliferation of papers lacking robust or novel findings. In this Editorial, we provide guidance for conducting & reporting high-quality analyses using open datasets🧪
plos.io/4poBmZo
Setting the standard for high-quality studies using open health datasets
Large open health datasets present unique opportunities for studies that when well-designed, conducted, and reported, can offer valuable contributions to health and medicine. However, recent years hav...
plos.io
December 10, 2025 at 2:21 PM
Next up in our 'meet the editors' is Academic Editor Brooke Nichols (@brookeenichols.bsky.social), Associate Professor of Global Health at Boston University School of Public Health (@busph.bsky.social). Brooke specializes in infectious disease modeling and health economics. 🧪 #MedSky #PLOSMedicine
December 9, 2025 at 5:22 PM
In this population health estimates analysis, Xiaojing Zeng and colleagues explore the distinct factors associated with declines in maternal mortality in Eastern and Western China, which may help inform efforts to reach global reduction targets 🧪 #MedSky
plos.io/44YcdfP
Social and health system factors associated with maternal mortality in Eastern and Western China: Population health estimates using provincial-level data
Xiaojing Zeng and colleagues, in a population health estimates analysis, explore the distinct factors associated with declines in maternal mortality in Eastern and Western China, which may help inform...
plos.io
December 9, 2025 at 4:59 PM
High blood pressure is recognized as a risk factor associated with the development of blood cancers. Here, the authors analyzed whether continuous use of the antihypertensive agent hydralazine is associated with a lower risk of hematologic neoplasms compared to other treatments 🧪
plos.io/48rqCDx
Association of hydralazine use with risk of hematologic neoplasms in patients with hypertension: A nationwide population-based cohort study in Taiwan
Li-Tzu Wang, Wu-Chien Chien and colleagues analyzed the association between long-term hydralazine use and the risk of hematologic neoplasms in patients with hypertension.
plos.io
December 9, 2025 at 10:39 AM
In this population-based cohort study, Daniel Myran and colleagues report that emergency or hospital care after hallucinogen use was associated with an increased risk of incident mania or bipolar disorder diagnosis 🏥🧪 #MedSky
plos.io/48nPZGq
Hospital-based care for hallucinogens and risk of mania and bipolar disorder: A population-based cohort study
Using a population-based cohort study, Daniel Myran and colleagues report that emergency or hospital care after hallucinogen use was associated with an increased risk of incident mania or bipolar diso...
plos.io
December 8, 2025 at 2:47 PM
In this Editorial, Zulfiqar Bhutta discusses the Global Burden of Disease 2023 report, outlining why, alongside improved data acquisition & analysis, its continued expansion creates new challenges & opportunities for improving its accuracy, completeness & policy relevance 🌏🧪 #GBD2023
plos.io/4rKtXVN
Global Burden of Disease 2023: Challenges and opportunities for a growing collaboration
In this Editorial, Zulfiqar Bhutta discusses the Global Burden of Disease (GBD) 2023 report, outlining why, alongside improved health monitoring, data acquisition, and analytical methods, its continue...
plos.io
December 8, 2025 at 10:50 AM
Over the next few weeks, as our Bluesky community grows, we will be introducing some of the PLOS Medicine Staff and Academic Editors, so that you can learn about their roles, areas of expertise, and their hopes for the journal and community. 🧪 #MedSky #PLOSMedicine #editors
December 4, 2025 at 4:15 PM
In this modeling study, Jiaxin Xie, Xuesi Dong, Zilin Luo and team use a multistate Markov model to quantify the long-term health and economic benefits of adhering to colorectal #cancer #screening, incorporating both traditional and biomarker-based initial screening methods 🧪 #MedSky
plos.io/4rB3nOT
The impact of adherence on colorectal cancer screening cost-effectiveness: A modeling study
Jiaxin Xie, Xuesi Dong, Zilin Luo, and team use a multistate Markov model to quantify the long-term health and economic benefits of adhering to colorectal cancer screening, incorporating both traditio...
plos.io
December 4, 2025 at 10:49 AM
Did you know that you may be eligible to publish in PLOS Medicine without paying an APC? All PLOS journals offer several APC-alternative business agreements through institutional partnerships.📝🧪

To learn more and find out if your institution has an agreement, visit: plos.org/libraries/pa...
Institutional Partners - PLOS
Institutional partners Open access is not truly open without equitable opportunities to publish. To support authors from diverse research communities, funding backgrounds…
plos.org
December 3, 2025 at 5:16 PM
In this retrospective cohort study, Josh Lamb and colleagues estimate the cumulative incidence of first-time reoperation following primary total hip replacement, taking into consideration different age groups, sex, and implant types to help guide treatment decisions. 🧪🦴 #MedSky
plos.io/4ougtL6
The association between implant design, age, sex and the rate of major reoperation in patients undergoing primary total hip replacement: A retrospective study of UK National Joint Registry and Hospita...
Josh N Lamb and colleagues estimate the cumulative incidence of first-time reoperation following primary total hip replacement, including revision for any cause or fixation of the femur for postoperat...
journals.plos.org
December 3, 2025 at 10:25 AM
What prospects are there for preventative & stem-cell based therapies for type 1 #diabetes? 💉
In this Perspective, Kevan Herold & colleagues highlight exciting therapeutic developments aimed at arresting or reversing T1D & discuss challenges they face in reaching the clinic🧪 #MedSky
plos.io/3XyyCwi
Towards insulin independence in type 1 diabetes: Prospects for prevention and cure
This Perspective highlights exciting developments in preventative treatments and stem cell-based therapies for type 1 diabetes, discussing the prospects and hurdles of arresting or reversing the disea...
plos.io
December 2, 2025 at 5:28 PM
In recognition of World AIDS Day 2025, this Perspective by Gregory Folkers & Anthony Fauci reflects on progress made in #antiretroviral treatments & prevention of HIV/AIDS, highlighting promising therapeutic developments and looking ahead to what is needed to end the #AIDS epidemic 🧪
plos.io/48np3Fu
Treatment and prevention of HIV/AIDS: Unfinished business
In recognition of World AIDS Day 2025, this Perspective by Gregory Folkers and Anthony Fauci reflects on the progress made in antiretroviral treatments and prevention of HIV/AIDS, highlighting promisi...
plos.io
December 1, 2025 at 7:04 PM
In this population-based study, Jehan Karim and colleagues investigate whether different policies of fetal anatomical ultrasound practice have an impact on the time of diagnosis of major fetal anomalies in England. 🧪 #MedSky #PLOSMed
plos.io/4oqDrmc
Impact of first-trimester ultrasound on early detection of major fetal anomalies: Nationwide population-based study of over 1 million pregnancies
In a population-based study, Jehan Karim and colleagues show that different policies of fetal anatomical ultrasound practice have an impact on the time of diagnosis of major fetal anomalies in England...
plos.io
December 1, 2025 at 2:58 PM
We are pleased to sponsor the online seminar, "Global Health After the Breakpoint: Evidence for What Comes Next", featuring a panel of experts to discuss the future of global health. It's not too late to register using the link below! 🧪
📆 Tuesday 2nd Dec
🕐3.00-4.30pm GMT
duke.zoom.us/webinar/regi...
November 28, 2025 at 4:42 PM
In this Perspective, Petra Heitkamp, Obioma Chijioke-Akaniro & @madhupai.bsky.social discuss why abrupt international funding cuts, while threatening #tuberculosis services, also present an opportunity for a more self-reliant response led by high-burden countries🧪
journals.plos.org/plosmedicine...
From dependence to self-reliance: The future of the global tuberculosis response
In this Perspective, Madhukar Pai and colleagues highlight that while international health aid cuts are impacting the tuberculosis response, they also present an opportunity to shift towards a more eq...
journals.plos.org
November 26, 2025 at 6:02 PM
In this cohort study, Valsamis and colleagues investigate the association between #BMI, patient complications and implant survival after shoulder replacement #surgery, finding that access to shoulder replacement should not be restricted based on BMI alone. ⬇️🧪 #MedSky #PLOSMed
plos.io/43PI1TM
The association of body mass index with patient outcomes after shoulder replacement surgery: Population-based cohort study using linked national data from the United Kingdom and Denmark
Epaminondas Markos Valsamis and colleagues investigate the association between BMI, patient complications and implant survival after shoulder replacement surgery using linked national datasets from th...
plos.io
November 24, 2025 at 2:19 PM
We pride ourselves on our commitments to open science, integrity, and equity in research. If you want to learn more, this Editorial by Executive Editor Helen Lumbard & Editor-in-Chief Till Bärnighausen outlines our scope and vision, and reaffirms our drive for meaningful change 🧪
plos.io/3XFZfzg
Charting the future of PLOS Medicine: Priorities for evidence, impact, and equity
As PLOS Medicine enters a new chapter, its leadership sets out a bold editorial vision grounded in evidence, impact and equity. In a rapidly evolving global health landscape, the journal reaffirms its...
plos.io
November 21, 2025 at 2:15 PM
We are thrilled to now be on BlueSky!

We prioritize studies addressing critical health challenges—from major diseases to health equity—that bridge scientific rigor with real-world impact, connecting researchers, clinicians, and policymakers to advance global health 🧬🧪

#OpenScience #MedSky
November 20, 2025 at 2:31 PM