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PLOS Medicine
@plosmedicine.org
Leading open access health science journal publishing impactful research that transforms global healthcare and advances clinical understanding.

🔗 https://journals.plos.org/plosmedicine
Despite many antihypertensive options, uncontrolled #hypertension remains pervasive. In this Perspective, Luke Laffin & Steven Nissen discuss the promise & challenges of aldosterone synthase inhibitors as the next breakthrough treatment of uncontrolled hypertension🧪 #CVD #MedSky
Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption
In this Perspective, Luke Laffin and Steven Nissen discuss the promise and challenges of aldosterone synthase inhibitors as the next breakthrough in the treatment of uncontrolled hypertension, the…
plos.io
February 11, 2026 at 2:01 PM
In recognition of International Day of Women and Girls in STEM, this Editorial by Aparajita Chattopadhyay reflects on the gender gap in #STEM in India, outlining socio-cultural & infrastructural factors, recent promising trends, and what is needed to continue these transformations 🧪
Let her shine: Empowering women and closing India’s gender gap in STEM
In recognition of International day of women and girls in STEM, this Editorial by Aparajita Chattopadhyay reflects on the gender gap in STEM in India, outlining socio-cultural and infrastructural…
plos.io
February 11, 2026 at 10:15 AM
Given recent advancements in digital technology, this systematic review and meta-analysis by Jack Le Vance and colleagues assesses whether teleultrasound is feasible, acceptable, diagnostically accurate and cost effective for antenatal care 🧪 #MedSky
plos.io/4raBqgo
Teleultrasound in obstetrics: A systematic review and meta-analysis
Given recent advancements in digital technology, Jack Le Vance and colleagues assess whether teleultrasound is feasible, acceptable, diagnostically accurate and cost effective for antenatal care.
plos.io
February 10, 2026 at 5:00 PM
In this study, Cameron M. Gee and colleagues investigated whether targeting spinal cord perfusion pressure via cerebrospinal fluid drainage after acute traumatic spinal cord injury leads to better neurologic recovery than standard mean arterial pressure targets 🧪 #MedSky
plos.io/4tpmoEZ
Targeting spinal cord perfusion pressure in acute spinal cord injury through cerebrospinal fluid drainage: A prospective multi-center clinical trial
Cameron M. Gee and colleagues not only report whether targeting spinal cord perfusion pressure via cerebrospinal fluid drainage after acute traumatic spinal cord injury leads to better neurologic reco...
plos.io
February 9, 2026 at 4:41 PM
In this mathematical modeling study, Alvaro Schwalb and colleagues estimate the global burden of viable Mycobacterium tuberculosis—that which can cause disease and be transmitted—to help guide disease prevention efforts 🧪 #tuberculosis #MedSky
plos.io/4aqzIQV
Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study
Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...
plos.io
February 9, 2026 at 12:04 PM
We are deeply saddened by the passing of Professor Sir Nicholas White. His pioneering research transformed malaria treatment worldwide, & his insight & generosity as an Academic Editor were invaluable to PLOS Medicine. Our thoughts are with his family, colleagues, & those whose lives he touched
February 9, 2026 at 10:15 AM
Optimal glycemic targets for women with gestational diabetes mellitus (GDM) are unclear. In this study, Lisa Douglas & colleagues investigate the effects of different glycemic targets during pregnancy in women with GDM on the health of mothers & their children 🧪 #MedSky
plos.io/4tmvh1V
Mother and child health 4.5 years after gestational diabetes mellitus managed using tight or less tight targets for glycaemic control: Post-hoc follow-up study of the TARGET trial
In a follow-up study to a cluster randomised study, Lisa Douglas and colleagues investigated the effects of tight or less tight glycemic targets during pregnancy in women with gestational diabetes, on...
plos.io
February 6, 2026 at 10:37 AM
Abstract deadlines are coming up for the @‌keystoneSymposia.bsky.social #CancerImmunotherapy meeting this March in Québec.

Learn more about key dates and submission details:
hubs.la/Q03Xlgbv0

#KSCancerImmune26
February 5, 2026 at 4:15 PM
The 2022 #mpox outbreak quickly made headlines and galvanized global attention; but the #epidemic is not over. In this Perspective, Rosamund Lewis & colleagues (@who.int) highlight ongoing mpox outbreaks across Africa & the world, & advocate for a sustained global response🧪 #MedSky
plos.io/45QeNFh
The mpox epidemic is not over: Reducing disproportionate burden in Africa and persistent global risk require a sustained response
The 2022 mpox outbreak quickly made headlines and galvanized global attention; but the epidemic is not over. In this Perspective, Rosamund Lewis and colleagues highlight ongoing mpox outbreaks across ...
plos.io
February 5, 2026 at 2:02 PM
In this Perspective, Giulia Notini & co discuss why the rapid expansion of antibody-drug conjugates, while redefining treatment options in advanced breast #cancer, has also resulted in several unresolved challenges for sequencing strategies, trial design, & drug development programs🧪
plos.io/3Mc25dp
Beyond the hype: Antibody-Drug Conjugates are advancing faster than our clinical strategy
In this Perspective, Giulia Notini and colleagues discuss why the rapid expansion of antibody-drug conjugates, while redefining treatment options in advanced breast cancer, has also resulted in severa...
plos.io
February 4, 2026 at 6:14 PM
Reposted by PLOS Medicine
For #WorldCancerDay, Associate Editor Jenny Tucker discusses the people-focused theme 'United by Unique', and talks to @plosone.org Section Editor Justin Brown and @plosmedicine.org Academic Editor James Brenton about a collaborative and personalized approach.

everyone.plos.org/2026/02/04/w...
World Cancer Day 2026: Continuing the theme of "United by Unique" - EveryONE
World Cancer Day 2024 Research Highlights, showcasing articles relevant to the theme of closing the cancer care gap and reducing care disparity.
everyone.plos.org
February 4, 2026 at 12:14 PM
It is recognized that adiposity increases liver cancer risk, but the specific biological mechanisms connecting them are not fully understood. In this study, Zhuo-Ying Li & colleagues identify metabolic mediators linking adiposity markers to liver cancer and assess potential causality
plos.io/3NTHUBv
Metabolomic insights into associations between adiposity markers and liver cancer risk: Results from a prospective cohort study and Mendelian randomization analysis
Zhuo-Ying Li and colleagues identify metabolic mediators linking adiposity markers to liver cancer in a nested case–control study, then assess their potential causality using a two-sample Mendelian ra...
plos.io
February 4, 2026 at 10:15 AM
In this population-based cohort study, Rita Patel & colleagues compare socioeconomic differences of multiple outcomes among patients aged 50+ years who underwent primary total hip replacement surgery for osteoarthritis in England 🧪 #MedSky
plos.io/46h0YQk
Social inequalities in patient outcomes after total hip replacement surgery for osteoarthritis in England: A population-based cohort study of the National Joint Registry
Rita Patel and colleagues compare area-level socioeconomic differences in multiple outcomes, such as 90-day mortality and 5-year revision rates, among patients aged 50 years and over who underwent pri...
plos.io
February 3, 2026 at 5:43 PM
Reposted by PLOS Medicine
PLOS Biology is proud to present our new collection of comment and opinionated review articles on the many facets of #immunometabolism!

🧪 #immunosky #immunology #metabolism

plos.io/4c5z6Cn

See 🧵⬇️ for more details
The many facets of immunometabolism
This Collection of articles aims to shine a light on the many facets of immunometabolism, highlighting how molecular and cellular mechanisms impact diverse tissue and organismal functions and the exci...
plos.io
February 3, 2026 at 10:36 AM
Experts across microbiology, cell biology, immunology, and clinical research will unite to tackle the global TB challenge. This @‌keystoneSymposia.bsky.social meeting highlights new technologies advancing our understanding of disease from bacteria to the human host.

buff.ly/1tdrFIP

#KSTB26
February 2, 2026 at 3:26 PM
Using Danish nationwide registry data of nearly 2 million women, Caroline H. Hemmingsen and colleagues evaluate the risk of #leukemia among pre-menopausal women using contemporary hormonal contraceptives 🧪#MedSky
plos.io/4kg44Kr
Leukemia in users of contemporary hormonal contraception: A nationwide registry-based cohort study among premenopausal women in Denmark
Using Danish nationwide registry data of nearly 2 million women, Caroline H. Hemmingsen and colleagues evaluate the risk of leukemia among pre-menopausal women using contemporary hormonal contraceptiv...
plos.io
February 2, 2026 at 10:30 AM
In this Editorial, PLOS Medicine Editor-in-Chief Till Bärnighausen and Executive Editor Helen Lumbard outline how #climate change and associated extreme weather events are threatening human health, and call for research on the effectiveness of climate adaptation interventions🧪🌍
plos.io/4adxog2
Intervention research to protect human health in the era of climate extremes
In this Editorial, PLOS Medicine Editor-in-Chief Till Bärnighausen and Executive Editor Helen Lumbard outline how climate change and associated extreme weather events are threatening human health, and...
plos.io
January 30, 2026 at 5:09 PM
Register now for on demand access to @keystoneSymposia.bsky.social: 'Long COVID and Other Post-Acute Infection Syndromes': hubs.la/Q03Xlbmv0

#KSLongCOVID26
January 29, 2026 at 4:45 PM
This @keystoneSymposia.bsky.social conference will address topics that go beyond tumor metabolism and explore the reciprocal relationship between cancer and whole-body metabolism. Find out more and register your place: hubs.la/Q03XlgKS0

#KSTumorMetab26
January 28, 2026 at 4:03 PM
In a secondary analysis of the C-STICH trial, Victoria Hodgetts Morton and colleagues investigate the association between progesterone treatment versus no treatment on #pregnancy outcomes in women at high risk of #preterm birth who had received a vaginal cervical cerclage 🧪 #MedSky
Pregnancy outcomes in women at high risk of preterm birth receiving a vaginal cervical cerclage with, or without, progesterone: A retrospective, secondary analysis of the C-STICH randomised controlled trial data
In a secondary analysis of the CSTICH trial, Victoria Hodgetts Morton and colleagues investigate the association between progesterone treatment versus no treatment on pregnancy outcomes in women at…
plos.io
January 27, 2026 at 5:45 PM
Next up in our 'meet the editors' is Academic Editor Peter MacPherson (@petermacp.bsky.social), Professor of Global Public Health and Head of Public Health at the University of Glasgow. Peter also specializes in infectious disease epidemiology, tuberculosis, HIV, and evidence synthesis 🧪 #MedSky
January 27, 2026 at 3:49 PM
Deadlines are fast approaching for @keystoneSymposia.bsky.social #Neuroinflammation in Health & Disease, this June in Whistler! See scholarship, abstract and discount registration dates: hubs.la/Q03XljQv0 #KSNeuroInflam26
January 26, 2026 at 2:22 PM
In this study, Daiki Tatematsu et al apply an "energy landscape analysis", which models multivariate psychological states as a dynamic system of interactions, to evaluate longitudinal changes in psychological distress among high school students before & during the COVID-19 pandemic🧪🧠
plos.io/4bjzrBk
Psychological distress among Japanese high school students during the COVID-19 pandemic: An energy landscape analysis
Daiki Tatematsu and colleagues apply an "energy landscape analysis," which models multivariate psychological states as a dynamic system of interactions, to evaluate longitudinal changes in psychologic...
plos.io
January 26, 2026 at 12:16 PM
Explore emerging research with field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, this March in Québec! hubs.la/Q03Xlgbv0 #KSCancerImmune26
January 23, 2026 at 4:45 PM
Reposted by PLOS Medicine
Our Section Editor Rubeena Zakar and coauthor Sarosh Iqbal give an Overview of @plos.org's Collection on Health Literacy, which is key to enhancing healthcare access, improving health outcomes and reducing health disparities.

journals.plos.org/plosone/arti...

collections.plos.org/collection/h...
Health Literacy
Health literacy refers to our knowledge of issues relating to our health and well-being, as well as the ability to understand and use information to make decisions about our health.
collections.plos.org
January 23, 2026 at 2:47 PM