Polymenidou Lab
@polylab.bsky.social
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We are a diverse team of scientists joined by our common interest in the molecular mechanisms of neurodegeneration. We study ALS and FTD at the University of Zurich: www.polymenidoulab.com
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Polymenidou Lab
@polylab.bsky.social
· Mar 28
Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures
TDP-43 pathology characterizes neurodegenerative diseases. Scialò et al. use in vitro-generated
and patient-derived TDP-43 aggregates as seeds to show that seed-induced TDP-43 cytoplasmic
aggregation ...
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