The Probst Lab
@probstlab.bsky.social
Group for Environmental Metagenomics, led by @alexjprobst.bsky.social
Microbial, viral, & geochemical interactions by linking meta'omics & microscopy
Managed by @geomicrosoares.bsky.social
Microbial, viral, & geochemical interactions by linking meta'omics & microscopy
Managed by @geomicrosoares.bsky.social
We are excited to share @probstlab.bsky.social's latest publication on the diversity of CRISPR-Cas spacers, led by @katharinasures.bsky.social !! 🧬
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Acquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural Environments
Abstract. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems of bacteria and archaea provide immunities
doi.org
November 17, 2025 at 12:09 PM
We are excited to share @probstlab.bsky.social's latest publication on the diversity of CRISPR-Cas spacers, led by @katharinasures.bsky.social !! 🧬
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Our own @alexjprobst.bsky.social @geomicrosoares.bsky.social and Cristina Moraru have recently authored a @natmicrobiol.nature.com Consensus Statement where they discuss new mechanisms for sequencing data reuse! 🧬💻
Check out their manuscript here:
www.nature.com/articles/s41...
Check out their manuscript here:
www.nature.com/articles/s41...
A roadmap for equitable reuse of public microbiome data - Nature Microbiology
In this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.
www.nature.com
September 30, 2025 at 8:03 AM
Our own @alexjprobst.bsky.social @geomicrosoares.bsky.social and Cristina Moraru have recently authored a @natmicrobiol.nature.com Consensus Statement where they discuss new mechanisms for sequencing data reuse! 🧬💻
Check out their manuscript here:
www.nature.com/articles/s41...
Check out their manuscript here:
www.nature.com/articles/s41...
Fresh out of the oven! 🍞
We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻
Small 🧵 below going through the main points 👇
www.biorxiv.org/content/10.1...
We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻
Small 🧵 below going through the main points 👇
www.biorxiv.org/content/10.1...
Uranium mining fuels evolution in deep groundwater microbiomes
Microbial communities in the deep biosphere underpin global biogeochemical cycles, yet their evolutionary responses to extensive anthropogenic disturbances remain unclear. Uranium in-situ leaching (IS...
www.biorxiv.org
August 7, 2025 at 8:05 AM
Fresh out of the oven! 🍞
We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻
Small 🧵 below going through the main points 👇
www.biorxiv.org/content/10.1...
We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻
Small 🧵 below going through the main points 👇
www.biorxiv.org/content/10.1...
Please RT this awesome opportunity to do a PhD at @unidue.bsky.social in collaboration with @jgi.doe.gov!! 🔥 Thanks!
The Central Collection of Algal Cultures (CCAC) at @unidue.bsky.social is advertising a 3-year PhD position supervised by the current Curator, Dr. Olga Matantseva!
This PhD will take place in close collaboration with the @jgi.doe.gov. 🦠🧬💻
Apply here: www.uni-due.de/karriere/ste...
This PhD will take place in close collaboration with the @jgi.doe.gov. 🦠🧬💻
Apply here: www.uni-due.de/karriere/ste...
July 31, 2025 at 3:10 PM
Please RT this awesome opportunity to do a PhD at @unidue.bsky.social in collaboration with @jgi.doe.gov!! 🔥 Thanks!
We’re happy to announce Dr. Lennard Stach!! 🥳🥳 Well done Lennard for a brilliant defense and thesis!! We will miss you!
Finally, thank you @leeselab.bsky.social for sitting in the thesis committee! 🫶
Finally, thank you @leeselab.bsky.social for sitting in the thesis committee! 🫶
July 16, 2025 at 2:48 PM
We’re happy to announce Dr. Lennard Stach!! 🥳🥳 Well done Lennard for a brilliant defense and thesis!! We will miss you!
Finally, thank you @leeselab.bsky.social for sitting in the thesis committee! 🫶
Finally, thank you @leeselab.bsky.social for sitting in the thesis committee! 🫶
Our @umweltstiftung.bsky.social fellow Linda Labecka presented her work at the most recent DBU conference! She works closely with the Institute for Artificial Intelligence in Medicine (@unidue.bsky.social & University Medicine Essen) and Universitätsklinikum Bonn (@unibonn.bsky.social)! 🧬💻
June 13, 2025 at 7:50 AM
Our @umweltstiftung.bsky.social fellow Linda Labecka presented her work at the most recent DBU conference! She works closely with the Institute for Artificial Intelligence in Medicine (@unidue.bsky.social & University Medicine Essen) and Universitätsklinikum Bonn (@unibonn.bsky.social)! 🧬💻
Our latest work is out - here, our own Dr. Sarah Eßer compares transcriptomic patterns of Altiarchaeum in Crystal Geyser (US) and the Muehlbacher sufidic spring (Germany)! 🧬
Read more below:
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Read more below:
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Differential Expression of Core Metabolic Functions in Candidatus Altiarchaeum Inhabiting Distinct Subsurface Ecosystems
Major differences between Candidatus Altiarchaeum species living in two distinct subsurface ecosystems as determined via metatranscriptomics. Genes overly expressed in different Ca. Altiarchaea in Mu...
enviromicro-journals.onlinelibrary.wiley.com
June 4, 2025 at 4:11 PM
Our latest work is out - here, our own Dr. Sarah Eßer compares transcriptomic patterns of Altiarchaeum in Crystal Geyser (US) and the Muehlbacher sufidic spring (Germany)! 🧬
Read more below:
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Read more below:
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Excited to welcome @hsintunglai.bsky.social and @renaandraes.bsky.social as PhD students to our group!! They will be working within Phase 2 of @crc-resist.bsky.social @unidue.bsky.social under the supervision of @alexjprobst.bsky.social and @cristinamoraru.bsky.social.
a person in a lab coat with the word let 's do this
ALT: a person in a lab coat with the word let 's do this
media.tenor.com
May 30, 2025 at 9:01 AM
Excited to welcome @hsintunglai.bsky.social and @renaandraes.bsky.social as PhD students to our group!! They will be working within Phase 2 of @crc-resist.bsky.social @unidue.bsky.social under the supervision of @alexjprobst.bsky.social and @cristinamoraru.bsky.social.
#TBT to @joernstarke.bsky.social and @katharinasures.bsky.social presenting their amazing work at the @vaam-microbes.bsky.social AC 2025 which took place at @ruhr-uni-bochum.de just last week! Well done you two!
@crc-resist.bsky.social @unidue.bsky.social
@crc-resist.bsky.social @unidue.bsky.social
April 3, 2025 at 4:19 PM
#TBT to @joernstarke.bsky.social and @katharinasures.bsky.social presenting their amazing work at the @vaam-microbes.bsky.social AC 2025 which took place at @ruhr-uni-bochum.de just last week! Well done you two!
@crc-resist.bsky.social @unidue.bsky.social
@crc-resist.bsky.social @unidue.bsky.social
Here's our latest group photo! Our lovely team keeps growing, as does our enthusiasm for doing great science together! 🦠🧬
March 31, 2025 at 8:47 AM
Here's our latest group photo! Our lovely team keeps growing, as does our enthusiasm for doing great science together! 🦠🧬
We’re looking forward to meeting all our science friends at the @vaam-microbes.bsky.social Annual Conference 2025 at @ruhr-uni-bochum.de !! 🧬🦠
On our side, we’re exceptionally giving two talks about our latest work:
⬇️
On our side, we’re exceptionally giving two talks about our latest work:
⬇️
March 24, 2025 at 6:07 AM
We’re looking forward to meeting all our science friends at the @vaam-microbes.bsky.social Annual Conference 2025 at @ruhr-uni-bochum.de !! 🧬🦠
On our side, we’re exceptionally giving two talks about our latest work:
⬇️
On our side, we’re exceptionally giving two talks about our latest work:
⬇️
Super happy to be hosting Prof. Richard Allen White III AKA @raw937.bsky.social from the University of North Carolina at Charlotte at @unidue.bsky.social for 3 surprisingly sunny weeks!! Great to have you around Rick!! 🦠🧬
March 17, 2025 at 2:02 PM
Super happy to be hosting Prof. Richard Allen White III AKA @raw937.bsky.social from the University of North Carolina at Charlotte at @unidue.bsky.social for 3 surprisingly sunny weeks!! Great to have you around Rick!! 🦠🧬
Want to know who’s replicating and who’s just hanging out in your enrichment cultures? Our new study led by @soansi.bsky.social shows how @nanoporetech.com long-read sequencing can reveal replication states, shedding light on microbial growth. 🦠🧬
See our latest publication: doi.org/10.1093/isme...
See our latest publication: doi.org/10.1093/isme...
Inferring replication states of bacteria and viruses in enrichment cultures via long-read sequencing
Abstract. Most microorganisms cannot be cultured in isolation, necessitating sophisticated methods for studying their (eco)physiology. While numerous appro
doi.org
March 11, 2025 at 8:15 AM
Want to know who’s replicating and who’s just hanging out in your enrichment cultures? Our new study led by @soansi.bsky.social shows how @nanoporetech.com long-read sequencing can reveal replication states, shedding light on microbial growth. 🦠🧬
See our latest publication: doi.org/10.1093/isme...
See our latest publication: doi.org/10.1093/isme...
Is stress response in stream sediments uniform across catchments? 🌊🦠
With @TheWrightonLab at CSU, we built river MAG & gene DBs and used metaT data to explore this while uncovering active stream microbiome metabolic functions!
Read our preprint here: doi.org/10.1101/2025...
@unidue.bsky.social
With @TheWrightonLab at CSU, we built river MAG & gene DBs and used metaT data to explore this while uncovering active stream microbiome metabolic functions!
Read our preprint here: doi.org/10.1101/2025...
@unidue.bsky.social
A uniform stress response of stream microbiomes in the hyporheic zone across North America
Background Stream hyporheic zones represent a unique ecosystem at the interface of stream water and surrounding sediments, characterized by high heterogeneity and accelerated biogeochemical activity. ...
doi.org
February 20, 2025 at 9:40 AM
Is stress response in stream sediments uniform across catchments? 🌊🦠
With @TheWrightonLab at CSU, we built river MAG & gene DBs and used metaT data to explore this while uncovering active stream microbiome metabolic functions!
Read our preprint here: doi.org/10.1101/2025...
@unidue.bsky.social
With @TheWrightonLab at CSU, we built river MAG & gene DBs and used metaT data to explore this while uncovering active stream microbiome metabolic functions!
Read our preprint here: doi.org/10.1101/2025...
@unidue.bsky.social
Quick PSA: we’ve officially deactivated our profile on Twitter/X and will henceforth only use Bluesky to communicate our science 😁
February 20, 2025 at 9:31 AM
Quick PSA: we’ve officially deactivated our profile on Twitter/X and will henceforth only use Bluesky to communicate our science 😁
We’re kicking off our Archean Park ERC project at @uni-muenster.de with @alexjprobst.bsky.social Jens Kallmeyer, Ivan Berg and Kai-Uwe Hinrichs & respective groups! Thanks very much to @donatogiovannelli.bsky.social and Prof. William Martin for giving invited talks to get us started!
January 13, 2025 at 1:30 PM
We’re kicking off our Archean Park ERC project at @uni-muenster.de with @alexjprobst.bsky.social Jens Kallmeyer, Ivan Berg and Kai-Uwe Hinrichs & respective groups! Thanks very much to @donatogiovannelli.bsky.social and Prof. William Martin for giving invited talks to get us started!
Reposted by The Probst Lab
@probstlab.bsky.social
@crc-resist.bsky.social
#1 on virus-host stress response in rivers tinyurl.com/43cjd6es
#2 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a
@alexjprobst.bsky.social
@unidue.bsky.social
Pls RT!
@crc-resist.bsky.social
#1 on virus-host stress response in rivers tinyurl.com/43cjd6es
#2 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a
@alexjprobst.bsky.social
@unidue.bsky.social
Pls RT!
Stellenausschreibung
tinyurl.com
December 20, 2024 at 7:43 AM
@probstlab.bsky.social
@crc-resist.bsky.social
#1 on virus-host stress response in rivers tinyurl.com/43cjd6es
#2 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a
@alexjprobst.bsky.social
@unidue.bsky.social
Pls RT!
@crc-resist.bsky.social
#1 on virus-host stress response in rivers tinyurl.com/43cjd6es
#2 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a
@alexjprobst.bsky.social
@unidue.bsky.social
Pls RT!
Reposted by The Probst Lab
We're hiring two bioinformatics-focused PhD students - one on microbial & epigenetic stress response in rivers, another on virus-host stress response in rivers! 🧬🦠💻
@unidue.bsky.social
@cristinamoraru.bsky.social
Please RT & spread the word - the @probstlab.bsky.social awaits you! 🦸
@idw-online.de
@unidue.bsky.social
@cristinamoraru.bsky.social
Please RT & spread the word - the @probstlab.bsky.social awaits you! 🦸
@idw-online.de
#PhD #position #alert
2 bioinfo PhD positions @ProbstLab @RESIST_CRC
#1 on microbial & epigenetic stress response in rivers
tinyurl.com/bdf8eu5a
#2 on virus-host stress response in rivers
tinyurl.com/43cjd6es (supervision Moraru)
Please share!
2 bioinfo PhD positions @ProbstLab @RESIST_CRC
#1 on microbial & epigenetic stress response in rivers
tinyurl.com/bdf8eu5a
#2 on virus-host stress response in rivers
tinyurl.com/43cjd6es (supervision Moraru)
Please share!
Stellenausschreibung
tinyurl.com
December 20, 2024 at 7:52 AM
We're hiring two bioinformatics-focused PhD students - one on microbial & epigenetic stress response in rivers, another on virus-host stress response in rivers! 🧬🦠💻
@unidue.bsky.social
@cristinamoraru.bsky.social
Please RT & spread the word - the @probstlab.bsky.social awaits you! 🦸
@idw-online.de
@unidue.bsky.social
@cristinamoraru.bsky.social
Please RT & spread the word - the @probstlab.bsky.social awaits you! 🦸
@idw-online.de
Reposted by The Probst Lab
Interested in multiple stressor research in rivers?
Interested in a PhD under excellent supervision in one of Europe’s largest freshwater research centres?
We seek 8 doctoral researchers for the CRC RESIST at the University of Duisburg-Essen!
sfb-resist.de/people/open-...
#rivers #PhDjobs
Interested in a PhD under excellent supervision in one of Europe’s largest freshwater research centres?
We seek 8 doctoral researchers for the CRC RESIST at the University of Duisburg-Essen!
sfb-resist.de/people/open-...
#rivers #PhDjobs
December 19, 2024 at 4:33 PM
Interested in multiple stressor research in rivers?
Interested in a PhD under excellent supervision in one of Europe’s largest freshwater research centres?
We seek 8 doctoral researchers for the CRC RESIST at the University of Duisburg-Essen!
sfb-resist.de/people/open-...
#rivers #PhDjobs
Interested in a PhD under excellent supervision in one of Europe’s largest freshwater research centres?
We seek 8 doctoral researchers for the CRC RESIST at the University of Duisburg-Essen!
sfb-resist.de/people/open-...
#rivers #PhDjobs
We’re hiring!! Come do a PhD with us using -omics to better understand river microbiomes responses to drought processes! ⬇️
December 19, 2024 at 5:10 PM
We’re hiring!! Come do a PhD with us using -omics to better understand river microbiomes responses to drought processes! ⬇️
Reposted by The Probst Lab
#PhD #position #alert
2 bioinfo PhD positions @ProbstLab @RESIST_CRC
#1 on microbial & epigenetic stress response in rivers
tinyurl.com/bdf8eu5a
#2 on virus-host stress response in rivers
tinyurl.com/43cjd6es (supervision Moraru)
Please share!
2 bioinfo PhD positions @ProbstLab @RESIST_CRC
#1 on microbial & epigenetic stress response in rivers
tinyurl.com/bdf8eu5a
#2 on virus-host stress response in rivers
tinyurl.com/43cjd6es (supervision Moraru)
Please share!
Stellenausschreibung
tinyurl.com
December 19, 2024 at 4:37 PM
#PhD #position #alert
2 bioinfo PhD positions @ProbstLab @RESIST_CRC
#1 on microbial & epigenetic stress response in rivers
tinyurl.com/bdf8eu5a
#2 on virus-host stress response in rivers
tinyurl.com/43cjd6es (supervision Moraru)
Please share!
2 bioinfo PhD positions @ProbstLab @RESIST_CRC
#1 on microbial & epigenetic stress response in rivers
tinyurl.com/bdf8eu5a
#2 on virus-host stress response in rivers
tinyurl.com/43cjd6es (supervision Moraru)
Please share!
We are grateful for the privilege of hosting Sigrid Neuhauser @sigridneuhauser.bsky.social today. She delivered a fascinating talk about her work on Phytomyxids. As part of the university network AURORA she currently visits the ProbstLab to foster scientific cooperations. 🥬🧬🥦
December 12, 2023 at 2:25 PM
We are grateful for the privilege of hosting Sigrid Neuhauser @sigridneuhauser.bsky.social today. She delivered a fascinating talk about her work on Phytomyxids. As part of the university network AURORA she currently visits the ProbstLab to foster scientific cooperations. 🥬🧬🥦