Piyush Sharma
@psharmaphd.bsky.social
Scientist at St. Jude Children’s Research Hospital.
Exploring the world of Nutrients as the controllers of the “Civilization”. #tcells #immunometabolism
Exploring the world of Nutrients as the controllers of the “Civilization”. #tcells #immunometabolism
Amazing study from @RoychoudhuriLab highlighting the next-gen genetic manipulation to tweak the right amount of protein expression to enhance T cell function in cancers. Kudos to the authors.
Check it out : www.nature.com/articles/s41...
#tcellexhaustion #tcells
Check it out : www.nature.com/articles/s41...
#tcellexhaustion #tcells
Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy - Nature Immunology
One of three back-to-back papers to show dosage of BACH2 can modulate T cell differentiation and function and how we might apply this to enhance chimeric antigen receptor T cell therapies for cancer.
www.nature.com
January 21, 2026 at 8:01 PM
Amazing study from @RoychoudhuriLab highlighting the next-gen genetic manipulation to tweak the right amount of protein expression to enhance T cell function in cancers. Kudos to the authors.
Check it out : www.nature.com/articles/s41...
#tcellexhaustion #tcells
Check it out : www.nature.com/articles/s41...
#tcellexhaustion #tcells
Thrilled to share our story published in @natimmunol.nature.com
We discovered a previously unknown metabolic regulatory event of T cell activation that affects their fate, providing a new perspective on T cell exhaustion. @stjuderesearch.bsky.social
Article: rdcu.be/exxhD
#Tcell #immunometabolism
We discovered a previously unknown metabolic regulatory event of T cell activation that affects their fate, providing a new perspective on T cell exhaustion. @stjuderesearch.bsky.social
Article: rdcu.be/exxhD
#Tcell #immunometabolism
Early methionine availability attenuates T cell exhaustion
Nature Immunology - The tumor environment is nutrient deficient. Here the authors show that early availability of methionine is critical for optimal T cell activation and prevents...
rdcu.be
July 25, 2025 at 4:12 AM
Thrilled to share our story published in @natimmunol.nature.com
We discovered a previously unknown metabolic regulatory event of T cell activation that affects their fate, providing a new perspective on T cell exhaustion. @stjuderesearch.bsky.social
Article: rdcu.be/exxhD
#Tcell #immunometabolism
We discovered a previously unknown metabolic regulatory event of T cell activation that affects their fate, providing a new perspective on T cell exhaustion. @stjuderesearch.bsky.social
Article: rdcu.be/exxhD
#Tcell #immunometabolism
Check out our chapter on ‘Adaptive Immunity and Metabolism’, in a recently published book by @elsevierconnect.bsky.social , highlighting the current understanding of how metabolites regulate adaptive immune system development and their response in diseases.
#immunometabolism
tinyurl.com/268f6sad
#immunometabolism
tinyurl.com/268f6sad
Metabolites as Signals in Immunity and Inflammation
Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinkin
tinyurl.com
July 16, 2025 at 2:05 AM
Check out our chapter on ‘Adaptive Immunity and Metabolism’, in a recently published book by @elsevierconnect.bsky.social , highlighting the current understanding of how metabolites regulate adaptive immune system development and their response in diseases.
#immunometabolism
tinyurl.com/268f6sad
#immunometabolism
tinyurl.com/268f6sad