🦋 Mix of basic & more advanced stuff (eg designing user-curated hashtag feeds)
🦋 Take a look & add any useful tips you have in the comments section
blog:
emcrit.org/pulmcrit/blu... #MedSky
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
would discharge home immediately (it doesn’t seem like this admission is even indicated?)
outpatient followup
honestly this guy needs good outpatient management, not a fancy hospitalization that will be super expensive
would discharge home immediately (it doesn’t seem like this admission is even indicated?)
outpatient followup
honestly this guy needs good outpatient management, not a fancy hospitalization that will be super expensive
Duration of therapy is a risk factor (>7 days).
Could likely be minimized by avoiding unnecessarily long courses.
TMP-SMX is usually well tolerated, but can wreak havok (SJS, ARDS, drug-induced meningitis). #EMIMCC
Duration of therapy is a risk factor (>7 days).
Could likely be minimized by avoiding unnecessarily long courses.
TMP-SMX is usually well tolerated, but can wreak havok (SJS, ARDS, drug-induced meningitis). #EMIMCC
Justin explores the many limitations of this trial but then admits that he does use CRT as a resus target.
I fundamentally agree.
Implementing imperfect data into practice is complicated. #EMIMCC
Justin explores the many limitations of this trial but then admits that he does use CRT as a resus target.
I fundamentally agree.
Implementing imperfect data into practice is complicated. #EMIMCC
Multiply a small & uncertain number with a big number and you get a big number
The final big number looks, well, really big
This grabs headlines & gets cited
It doesn’t clarify underlying uncertainty, so it doesn’t actually illuminate anything
Mathematically rigorous clickbait
Multiply a small & uncertain number with a big number and you get a big number
The final big number looks, well, really big
This grabs headlines & gets cited
It doesn’t clarify underlying uncertainty, so it doesn’t actually illuminate anything
Mathematically rigorous clickbait
I’ve argued against this for years (it delays tx for 3 days & you miss optimal window for intervention)
HRS-AKI carries a massive ~30% in-hospital mortality, its an emergency…
I’ve argued against this for years (it delays tx for 3 days & you miss optimal window for intervention)
HRS-AKI carries a massive ~30% in-hospital mortality, its an emergency…
if they are healthy enough to tolerate closure (MELD <11), IR ligation of the shunt improves encephalopathy
this case👇 is extremely unusual
if they are healthy enough to tolerate closure (MELD <11), IR ligation of the shunt improves encephalopathy
this case👇 is extremely unusual
adjust q4hr??
the whole point of a NE gtt in HRS-AKI is immediate BP control
tell the ICU RN the target MAP and they will achieve it immediately... that's why NE gtts are great
(and peripheral IV is fine)
adjust q4hr??
the whole point of a NE gtt in HRS-AKI is immediate BP control
tell the ICU RN the target MAP and they will achieve it immediately... that's why NE gtts are great
(and peripheral IV is fine)
This is largely intuitive and common sense, but it's useful to have a guideline if needed for reference. #EMIMCC
www.neurology.org/doi/pdf/10.1...
This is largely intuitive and common sense, but it's useful to have a guideline if needed for reference. #EMIMCC
www.neurology.org/doi/pdf/10.1...
even if the kidneys take 24-48 hrs to start working, isotonic bicarb resus can often drop the K & improve pH enough to avoid needing dialysis (buys time for renal recovery)
-Restore volume, incr kidney perfusion leading to incr urine output + K elimination
-0.9% saline: pH 5.5, big Cl load. Worsen acidosis leading incr serum K
-LR superior: small amount of K in it won’t raise serum K. Won’t contribute to acidosis
youtube.com/shorts/3G4yc...
#EMIMCC
even if the kidneys take 24-48 hrs to start working, isotonic bicarb resus can often drop the K & improve pH enough to avoid needing dialysis (buys time for renal recovery)
We’re barely recovering from the last RN shortage and they want to create another one 😫
Literally zero patients survive the ICU without outstanding RN care.
www.newsweek.com/nursing-not-...
We’re barely recovering from the last RN shortage and they want to create another one 😫
Literally zero patients survive the ICU without outstanding RN care.
www.newsweek.com/nursing-not-...
Finer point: administration of metaclopramide + erythromycin
Promotility agents which help empty the stomach of blood, improve the view for endoscopist
youtube.com/shorts/ae98W...
#EMIMCC
Finer point: administration of metaclopramide + erythromycin
Promotility agents which help empty the stomach of blood, improve the view for endoscopist
youtube.com/shorts/ae98W...
#EMIMCC
Looks lame
The strength of MedTwitter has always been diversity (geographic & training - docs, RNs, PAs, pharmacists etc)
Further fractionating our community isn't the way forward
I think Bluesky is ideal; we just need more people here
Looks lame
The strength of MedTwitter has always been diversity (geographic & training - docs, RNs, PAs, pharmacists etc)
Further fractionating our community isn't the way forward
I think Bluesky is ideal; we just need more people here
This algorithm is where I ended up 👇
Therapies should be based on several factors (not solely whether CRT is <3; CRT isn't precise so this dichotomy is problematic)
Beware of vasopressin; it may depress digital perfusion & block the goal #EMIMCC
This algorithm is where I ended up 👇
Therapies should be based on several factors (not solely whether CRT is <3; CRT isn't precise so this dichotomy is problematic)
Beware of vasopressin; it may depress digital perfusion & block the goal #EMIMCC
Intervention group: fix macrohemodynamics, then target Pi >1.4
I think they're right
Pi is similar to cap refill, but continuously displayed number on monitor 😍
pubmed.ncbi.nlm.nih.gov/41033063/ #EMIMCC
Intervention group: fix macrohemodynamics, then target Pi >1.4
I think they're right
Pi is similar to cap refill, but continuously displayed number on monitor 😍
pubmed.ncbi.nlm.nih.gov/41033063/ #EMIMCC
(anaphylactoid rxns = angry mast cells spit out histamine; usually less severe than anaphylaxis)
Canadian guidelines: don't pre-treatment w/ steroid, give antihistamine
This makes physiological sense!
Thank you science! #1/3. #EMIMCC
youtube.com/watch?v=h2Hv...
(anaphylactoid rxns = angry mast cells spit out histamine; usually less severe than anaphylaxis)
Canadian guidelines: don't pre-treatment w/ steroid, give antihistamine
This makes physiological sense!
Thank you science! #1/3. #EMIMCC
Don't use ACEi/ARB for management of HTN in patients who are tenuous or have limited prognosis (eg advanced malignancy). There are much safer anti-HTN tx's (amlodipine, nifedipine XR).
Educate patients that if they're too sick to eat they should to hold ACEi/ARB #EMIMCC
Don't use ACEi/ARB for management of HTN in patients who are tenuous or have limited prognosis (eg advanced malignancy). There are much safer anti-HTN tx's (amlodipine, nifedipine XR).
Educate patients that if they're too sick to eat they should to hold ACEi/ARB #EMIMCC
Can you estimate optimal PEEP in any BMI with the simple equation of BMI/3?
Maybe!
Our new paper comparing esophageal pressure base transpulmonary pressure estimates of optimal PEEP (tPP of 0 +\-2) vs BMI/3 in OR patients
www.sciencedirect.com/science/arti...
Can you estimate optimal PEEP in any BMI with the simple equation of BMI/3?
Maybe!
Our new paper comparing esophageal pressure base transpulmonary pressure estimates of optimal PEEP (tPP of 0 +\-2) vs BMI/3 in OR patients
www.sciencedirect.com/science/arti...
(e.g., these two 2025 review articles reach totally different conclusions! Lajoye is correct IMHO)
TLDR: there is no simple answer; personalize tx 🌌
my current take on vaso in sepsis is here: emcrit.org/ibcc/shock/#... #EMIMCC
(e.g., these two 2025 review articles reach totally different conclusions! Lajoye is correct IMHO)
TLDR: there is no simple answer; personalize tx 🌌
my current take on vaso in sepsis is here: emcrit.org/ibcc/shock/#... #EMIMCC
This is basically where POCUS was 1995-2005
Technology & evidence-basis are improving
Early adopters may be interested
IMHO anything bringing us to the bedside more & forcing us to engage w/ the exam is good
emcrit.org/ibcc/pocit/ #EMIMCC
This is basically where POCUS was 1995-2005
Technology & evidence-basis are improving
Early adopters may be interested
IMHO anything bringing us to the bedside more & forcing us to engage w/ the exam is good
emcrit.org/ibcc/pocit/ #EMIMCC
-0.9% NaCl: 154 mEq Na + 154 mEq Cl. pH ~ 5.6
-Human/animal data shows it's proinflammatory
-SALT-ED (PMID:29485926) + SMART (PMID:29485925) show incr kidney injury w/ 0.9% NaCl vs balanced solutions
-LR more physiologic
youtube.com/shorts/XcV7R...
#EMIMCC
-0.9% NaCl: 154 mEq Na + 154 mEq Cl. pH ~ 5.6
-Human/animal data shows it's proinflammatory
-SALT-ED (PMID:29485926) + SMART (PMID:29485925) show incr kidney injury w/ 0.9% NaCl vs balanced solutions
-LR more physiologic
youtube.com/shorts/XcV7R...
#EMIMCC