Author | Lightnews

Raj Rajnarayanan @rajlabn.bsky.social · 2d

Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters (> 100 Seqs w/ collection dates in the last 30 days): #UnitedKingdom #USA #France #Canada #Spain #Netherlands #Australia #Germany #Italy

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Raj Rajnarayanan @rajlabn.bsky.social · 2d

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 09/25/2025 (4,684 sequences)

Note: 164,341 SARSCoV2 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

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Raj Rajnarayanan @rajlabn.bsky.social · 2d

Tracking #SARSCoV2 #Lineages - Globally |10/26/25

Top lineages -#30DayTrends #G30

XFG.3 (8.4%)
XFG.3.4.1 (6.7%)
XFG.5.1 (4.5%)
NB.1.8.1 (4.4%)
XFG.2 (3.6%)
XFG (3.4%)
XFG.4.1 (2.8%)
XFG.8 (2.6%)
XFG.6 (2.6%)
XFG.3.4 (2.5%)

Tracker: public.tableau.com/app/profile/...

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Raj Rajnarayanan @rajlabn.bsky.social · 12d

These are sequences with sample collection dates in the last 30 days - I can check if this is missing some seqs

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Raj Rajnarayanan @rajlabn.bsky.social · 12d

Following BA.3.2.2* in #WesternAustralia closely

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Raj Rajnarayanan @rajlabn.bsky.social · 12d

Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters (> 100 Seqs w/ collection dates in the last 30 days): #Canada #USA #UnitedKingdom #Spain #France #Australia #Netherlands #Italy #Germany

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Raj Rajnarayanan @rajlabn.bsky.social · 12d

This analysis includes #SARSCoV2 sequences submitted to
@GISAID with sample collection dates on or after 09/16/2025 (5,714 sequences)

Note: 157,144 SARSCoV2 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

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Raj Rajnarayanan @rajlabn.bsky.social · 12d

Tracking #SARSCoV2 #Lineages - Globally |10/16/25

Top lineages -#30DayTrends #G30

XFG.3 (9.2%)
NB.1.8.1 (5.3%)
XFG.2 (5.3%)
XFG.3.4.1 (4.8%)
XFG.5.1 (3.8%)
XFG.8 (3.2%)
XFG.4.1 (2.9%)
XFG (2.6%)
XFG.6 (2.1%)
PQ.17 (2%)

Tracker: public.tableau.com/app/profile/...

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Raj Rajnarayanan @rajlabn.bsky.social · 23d

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 08/29/2025 (4,212 sequences)

Note: 146,261 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 15

XFG* mutations under watch

Spike K529T is worth watching (its one of the signature mutations of XFG.14 lineage)

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 15

Status of #COVID19 in #California

XFG.3, XFG, XFG.2 and PQ.2 are the top circulating #SARSCoV2 lineages in CA |[🚨Low sequence count]

#COVID19 hospitalizations -low | #WasteWater #SARSCoV2 - Very High | @capublichealth.bsky.social

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 15

Status of #COVID19 in #NewYork (#Bellwether State)

XFG and XFG.3 are the top circulating #SARSCoV2 lineages in NY [🚨low sequence count]

#COVID19 hospitalizations - trending up| #WasteWater #SARSCoV2 -low | @HealthNYGov

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 15

#COVID19 #VariantDashboard - #USA| 09/14/25

#SARSCoV2 #Lineages #30DAYTRENDS

XFG (35.9%)
XFG.3 (24.8%)
XFG.2 (14.2%)
NB.1.8.1 (6.3%)
PQ.2 (3.4%)
XFG.3.1 (2.2%)
LP.8.1.1 (1.4%)
NW.1.2 (1.4%)
NW.1 (1.1%)
XFC (1.1%)
PY.1 (0.8%)

Tracker: tinyurl.com/mryj4uu7

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 14

XFG.3* is the top circulating variant group in the world!

Top XFG sub-lineages in circulation (>=1%)

XFG.3, XFG, XFG.5, XFG.2, XFG.3.4.1, XFG.4.1,
XFG.9, XFG.8, XFG.3.1, XFG.3.4, XFG.6, XFG.3.4.3,
XFG.14.1, XFG.3.4.2, XFG.22, XFG.10, XFG.4, XFG.3.1.2,
XFG.21

102 XFG sub-lineages:

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 14

Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters #USA #Spain #UK #Canada #Australia #NewZealand #France #Brazil #Italy #SouthKorea #Netherlands #PuertoRico #Japan #Denmark #Ukraine #Singapore #China
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Raj Rajnarayanan @rajlabn.bsky.social · Sep 14

Tracking #SARSCoV2 #Lineages - Globally |09/14/25

Top lineages -#30DayTrends #G30

XFG (32.1%)
XFG.3 (23%)
NB.1.8.1 (13.3%)
XFG.2 (5.2%)
PQ.2 (4.5%)
XFG.3.1 (3.3%)
PE.1 (2.4%)
PQ.1 (1.1%)
PQ.10 (1.1%)
LP.8.1.1 (1%)

Tracker: public.tableau.com/app/profile/... 1/n

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 9

Status of #COVID19 in #California

XFG, XFG.3, NB.1.8.1, PQ.2 and XFG.2 are the top circulating #SARSCoV2 lineages in CA |[🚨Low sequence count]

#COVID19 hospitalizations -low but trending up| #WasteWater #SARSCoV2 - Very High |
@CAPublicHealth

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 9

Status of #COVID19 in #NewYork (#Bellwether State)

XFG, XFG.3, XFG.2, XFG.3.1 and NB.1.8.1 are the top circulating #SARSCoV2 lineages in NY
[🚨low sequence count]

#COVID19 hospitalizations - trending up| #WasteWater #SARSCoV2 -low |
@HealthNYGov

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 9

#COVID19 #VariantDashboard - #USA| 09/08/25

#SARSCoV2 #Lineages #30DAYTRENDS

XFG (34.4%)
XFG.3 (22.2%)
XFG.2 (15.4%)
NB.1.8.1 (7.1%)
PQ.2 (3.6%)
NW.1.2 (2.8%)
XFG.3.1 (1.9%)
LP.8.1.1 (1.2%)
PQ.1 (0.9%)

Tracker: tinyurl.com/mryj4uu7

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 2

XFG.3* is the top circulating variant group in the world!

Top XFG sub-lineages in circulation -
XFG.3; XFG; XFG.2; XFG.5; XFG.9; XFG.3.4.1; XFG.4.1; XFG.8; XFG.3.1; XFG.10; XFG.3.4.2; XFG.4

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 2

Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters #USA #Spain #UK #Canada #NewZealand #Singapore #Australia #France #SouthKorea #China #Denmark #Brazil #Ireland #PuertoRico #Germany #Japan #Ukraine

3/n

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 2

This analysis includes #SARSCoV2 sequences submitted to
@GISAID with sample collection dates on or after 08/02/2025 (3,277 sequences)

Note: Tracker includes ~120K seqs w/ collection dates on or after 01/01/2025 (seqs with significant date errors are not included)

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Raj Rajnarayanan @rajlabn.bsky.social · Sep 2

Tracking #SARSCoV2 #Lineages - Globally |09/01/25

Top lineages -#30DayTrends #G30

XFG (31.5%)
XFG.3 (20%)
NB.1.8.1 (13.4%)
XFG.2 (6%)
PQ.2 (5%)
XFG.3.1 (3.5%)
PQ.1 (1.8%)
LP.8.1.1 (1.3%)
PQ.10 (1.3%)
MC.10.2.1 (1.2%)

Tracker: public.tableau.com/app/profile/... 1/n

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Raj Rajnarayanan @rajlabn.bsky.social · Aug 29

Status of #COVID19 in #California

XFG.3, XFG.2 and XFG are the top circulating #SARSCoV2 lineages in CA

#COVID19 hospitalizations -low but trending up| #WasteWater #SARSCoV2 - High |
@CAPublicHealth

1 5

Raj Rajnarayanan @rajlabn.bsky.social · Aug 29

Status of #COVID19 in #NewYork (#Bellwether State)

XFG.3, XFG and XFG.2 are the top circulating #SARSCoV2 lineages in NY

#COVID19 hospitalizations - trending up| #WasteWater #SARSCoV2 -trending up |
@HealthNYGov

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