Ravi Dashnamoorthy
@ravidmurthy.bsky.social
Oncology Therapeutic Drug R&D, Medical Biochemist, Genomics and Metabolomics.
#AACR2025, several rows of empty poster boards, some posters were not even attended. Changing interests and themes, crowds mostly focused on DNA repair/cell cycle inhibitors or Degraders. Not so much on CAR-T, Systems biology is lost in translation, not sure where cancer research is headed.
April 30, 2025 at 4:58 PM
#AACR2025, several rows of empty poster boards, some posters were not even attended. Changing interests and themes, crowds mostly focused on DNA repair/cell cycle inhibitors or Degraders. Not so much on CAR-T, Systems biology is lost in translation, not sure where cancer research is headed.
Hi All, please see this active discussion board, about a recent publication in Lancet Oncology, which is an insult to science and these authors have "0" credibility without any publications metabolism or clinical studies on this topic.
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Redirecting...
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December 20, 2024 at 3:37 PM
Hi All, please see this active discussion board, about a recent publication in Lancet Oncology, which is an insult to science and these authors have "0" credibility without any publications metabolism or clinical studies on this topic.
www.facebook.com/share/1D8Qqe...
www.facebook.com/share/1D8Qqe...
MSN
www.msn.com
December 16, 2024 at 10:25 PM
December 13, 2024 at 3:20 PM
We recently mapped the biological progression maps in human tumors. This study shows how cancer can behave like "Charlotte's web" when it comes to targeting with precision medicine. How we can use certain drugs to reverse biological progression etc., pmc.ncbi.nlm.nih.gov/articles/PMC...
An Analysis of Transcriptomic Burden Identifies Biological Progression Roadmaps for Hematological Malignancies and Solid Tumors
Biological paths of tumor progression are difficult to predict without time-series data. Using median shift and abacus transformation in the analysis of RNA sequencing data sets, natural patient strat...
pmc.ncbi.nlm.nih.gov
November 25, 2024 at 5:35 PM
We recently mapped the biological progression maps in human tumors. This study shows how cancer can behave like "Charlotte's web" when it comes to targeting with precision medicine. How we can use certain drugs to reverse biological progression etc., pmc.ncbi.nlm.nih.gov/articles/PMC...
This study solves the mechanistic basis of 100 year old Warburg's paradox. Please show your support by reading/commenting about this study.
This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...
Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma
Background/Objectives: Warburg’s metabolic paradox illustrates that malignant cells require both glucose and oxygen to survive, even after converting glucose into lactate. It remains unclear whether s...
doi.org
November 25, 2024 at 5:32 PM
This study solves the mechanistic basis of 100 year old Warburg's paradox. Please show your support by reading/commenting about this study.
www.msn.com/en-us/health...
Next big advancement in Antibody Drug Conjugate based therapy, customizable and cheaper.
Next big advancement in Antibody Drug Conjugate based therapy, customizable and cheaper.
MSN
www.msn.com
November 25, 2024 at 5:29 PM
www.msn.com/en-us/health...
Next big advancement in Antibody Drug Conjugate based therapy, customizable and cheaper.
Next big advancement in Antibody Drug Conjugate based therapy, customizable and cheaper.
Reposted by Ravi Dashnamoorthy
This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...
Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma
Background/Objectives: Warburg’s metabolic paradox illustrates that malignant cells require both glucose and oxygen to survive, even after converting glucose into lactate. It remains unclear whether s...
doi.org
November 12, 2024 at 8:25 PM
This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...
This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...
Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma
Background/Objectives: Warburg’s metabolic paradox illustrates that malignant cells require both glucose and oxygen to survive, even after converting glucose into lactate. It remains unclear whether s...
doi.org
November 12, 2024 at 8:25 PM
This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...