Lightnews — Scholar-powered news

Reposted by Roberta Azzarelli

Joaquina Delas @joadelas.bsky.social · Jul 21

Excited to share our latest work with @jamesbriscoe.bsky.social .

A global #cis-regulatory temporal program guides how spatial cues are interpreted in neural progenitors. We show how #space and #time can be integrated to generate cell type diversity in the #spinalcord.

Congrats to all authors.

UCL Faculty of Life Sciences @ucllifesciences.bsky.social · Jul 21

A study from @crick.ac.uk and @ucllifesciences.bsky.social reveals how timing mechanisms, not just spatial cues, shape cell identity during spinal cord development. The findings open up new avenues for both basic developmental biology and clinical applications.
www.sciencedirect.com/science/arti...

The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube

The vertebrate neural tube generates a large diversity of molecularly and functionally distinct neurons and glia from a small progenitor pool. While t…

www.sciencedirect.com

2 16 40

Roberta Azzarelli @robertazzarelli.bsky.social · Jun 19

Glad to share our review on Cell fate acquisition and reprogramming by ASCL1

Big shout out to Jethro Lundie-Brown, Francesca Puletti and Anna Philpott

Collaboration between @scicambridge.bsky.com @ucl.ac.uk @ucllifesciences.bsky.com School of Pharmacy

royalsocietypublishing.org/doi/10.1098/...

Cell fate acquisition and reprogramming by the proneural transcription factor ASCL1 | Open Biology

ASCL1 is a key member of the proneural basic helix-loop-helix (bHLH) transcription factor (TF) family and it plays diverse roles in nervous system development and maintenance. ASCL1 is also one of the...

royalsocietypublishing.org

2 7

Roberta Azzarelli @robertazzarelli.bsky.social · Jun 12

A pleasure to host the Jean Banister Prize Lecture @ucl.ac.uk School of Pharmacy
Thank you Sylvia for a fantastic lecture! And many thanks to Annette, Mala Shah and the Physiological Society
@sylviaschroeder.bsky.social @annieneuro.bsky.social @physoc.bsky.social

2

Reposted by Roberta Azzarelli

Annette Dolphin @annieneuro.bsky.social · Jun 12

Great lecture on visual processing given by @sylviaschroeder.bsky.social
She is the winner of 2025 R Jean Banister prize for early career scientists, awarded by @physoc.bsky.social .

Thanks to Marreo Carandini for the photo

1 3 4

Reposted by Roberta Azzarelli

Friedel Lab @labfriedel.bsky.social · Jun 5

Congratulations @sangjokang.bsky.social and #zoulab for this pioneering study on how #microglia shape invasion of brain cancer through cell collision mechanism via Plexin-B2. 축하해요 ! www.nature.com/articles/s43...
@sinaibrain.bsky.social

1 4

Roberta Azzarelli @robertazzarelli.bsky.social · Jun 4

🧠 ‘How vision is shaped by behaviour and internal states’ 🧠

All welcome! Looking forward to it!

Roberta Azzarelli @robertazzarelli.bsky.social · Jun 4

Please mark this in your calendar! 👇🏼
Wed 11th June 4pm @ucllifesciences.bsky.social School of Pharmacy, we host R Jean Banister Prize Lecture @physoc.bsky.social from Dr Sylvia Schroeder
@sylviaschroeder.bsky.social Uni of Sussex

1 2 1

Roberta Azzarelli @robertazzarelli.bsky.social · May 17

Please join us for the next Pharmacology seminar series @ucl.ac.uk @ucllifesciences.bsky.social School of Pharmacy

Dr Irving Aye will talk on Metabolic control of epigenetics in placenta on 21st of May! Coming very soon!!

1 2

Reposted by Roberta Azzarelli

London Stem Cell Network @lscn.bsky.social · May 6

And to round off the day, the perfect conclusion to our symposium, a broad exploration and thorough discourse of the history and state of the art in molecular developmental haematology from Prof. @BertieGottgens of Cambridge Stem Cell Institute.

#science #research

1 5

Reposted by Roberta Azzarelli

London Stem Cell Network @lscn.bsky.social · May 6

Invited speaker Prof. Selina Wray leading Session 2: Stem cell models of health and disease. An exciting journey through her use of, and novel insights from, patient-derived iPSC models of Alzheimer’s Disease.

1 2 6

Reposted by Roberta Azzarelli

London Stem Cell Network @lscn.bsky.social · May 6

Symposium kicked off with an energising Flagship Lecture from @inesequeira.bsky.social , presenting work decoding epithelial tissue regeneration and cell type heterogeneity using multi-omic and cellular dynamics data.

1 8

Roberta Azzarelli @robertazzarelli.bsky.social · Apr 5

Did I say that the Pharmacology seminar series @ucl.ac.uk @ucllifesciences.bsky.social School of Pharmacy is in full swing?

Yes. After the success of @MootazSalman, we will have @MikkoAiravaara 16thApril and @IrvingAye 21stMay (none on bsky yet 😊)

1

Roberta Azzarelli @robertazzarelli.bsky.social · Apr 5

The Pharmacology seminar series @ucl.ac.uk @ucllifesciences.bsky.social School of Pharmacy is in full swing!

Thank you @MootazSalman @ox.ac.uk for a fantastic seminar! Contagious enthusiasm and great science! Thank you for coming!
And thanks to Prof. Afia Ali for bringing him in!

1

Reposted by Roberta Azzarelli

UCL Faculty of Life Sciences @ucllifesciences.bsky.social · Mar 4

Discover how our researchers are creating real-world impact, developing innovative solutions to tackle humanity's most pressing challenges.
Watch the full video here: shorturl.at/mYLQV

9 16

Reposted by Roberta Azzarelli

London Stem Cell Network @lscn.bsky.social · Feb 21

📢Registration for #LSCN2025 is now open! We have a fantastic lineup of speakers and more to be confirmed!

Secure your place today eventbrite.co.uk/e/8th-annual... and submit your abstract for a chance to present your #stemcell work docs.google.com/forms/d/e/1F...

1 5 6

Roberta Azzarelli @robertazzarelli.bsky.social · Jan 17

London Stem Cell Network @lscn.bsky.social is on Bsky! Hello! Please follow☝🏻 if interested in stem cells

8 14

Reposted by Roberta Azzarelli

Development @dev-journal.bsky.social · Jan 6

Issue 24 is complete!

On the cover: Confocal microscope image of a mouse embryonic kidney section identifying the metanephric mesenchyme (WT1+, cyan) and the ureteric bud epithelium (CDH1+, magenta) during early renal branching morphogenesis. See article by Franks & Allen:
doi.org/10.1242/dev....

Confocal microscope image of a mouse embryonic kidney section identifying the metanephric mesenchyme (WT1+, cyan) and the ureteric bud epithelium (CDH1+, magenta) during early renal branching morphogenesis. See Research article by Franks and Allen

1 3 10

Roberta Azzarelli @robertazzarelli.bsky.social · Dec 20

😂 so true..

1

Reposted by Roberta Azzarelli

Development @dev-journal.bsky.social · Dec 17

ASCL1 is a better chromatin remodeller when unphosphorylated

Read this Research Highlight showcasing work from Roberta Azzarelli (@robertazzarelli.bsky.social @ucllifesciences.bsky.social), Anna Philpott and colleagues:
https://journals.biologists.com/dev/article/151/24/e151_e2401/363434/

Figure 1 (C) Representative immunostaining images for Tubb3 (green) in ESCs in pluripotency, NE and MS after 48 h of WT or SA ASCL1 induction or in control cells. DAPI nuclear counterstain (blue). Scale bars: 100 μm.

1 2 9

Roberta Azzarelli @robertazzarelli.bsky.social · Dec 14

Please add me, thank you!

1 2

Roberta Azzarelli @robertazzarelli.bsky.social · Dec 12

And I should not forget to thank the Cambridge community at the Stem Cell Institute and the UCL community at the School of Pharmacy for creating supporting and welcoming environments @ucllifesciences.bsky.social