Rubin Dasgupta
@rubindg.bsky.social
26 followers 12 following 7 posts
> Scientifically a Marie-Curie and Moderna Postdoctoral Fellow at Uppsala University with expertise in NMR spectroscopist, RNA biologist, and Protein Biochemist > Personally an avid book reader with emphasis on Epic Fantasy 📖
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Reposted by Rubin Dasgupta
stonebutcher.bsky.social
Check out our new method for targeted DNP-enhanced NMR of RNA using site-directed spin labeling, now live as a preprint on ChemRxiv:

doi.org/10.26434/che...

A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.
rubindg.bsky.social
Looking forward to discuss #RNA #Science at the 30th @rnasociety.bsky.social meeting. I will be presenting our recent work on employing state-of-the-art #solid-state #NMR methods to study dynamics in microRNA-Argonaute complex in the Concurrent session 16 about miRNA and siRNA (T-149).
rubindg.bsky.social
Congratulations 🎉
rubindg.bsky.social
That’s a very dedicated purification 😅
rubindg.bsky.social
For the last year I spent sometime learning #ONT #Nanopore sequencing and we decided to get this amazing P2 Solo. Can’t wait to start acquiring some in-house data. #RNAbiology #ChemicalProbing #RNA
rubindg.bsky.social
Amazing article highlighting the important discoveries in RNA biology cementing its role in evolution of life
rubindg.bsky.social
Can increasing the sensitivity of #NMRspectroscopy provide some insight into #microRNA and #Argonaute interaction?
The answer is a resounding Yes.
Find out more in our recent study where we used #DynamicNuclearPolarisation to study this complex
doi.org/10.1093/nar/...
Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR
Abstract. Understanding mRNA regulation by microRNA (miR) relies on the structural understanding of the RNA-induced silencing complex (RISC). Here, we eluc
doi.org