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3D imaging demonstrates that amyloid β deposits in cerebral amyloid angiopathy progress from surface arteries to deeper brain vessels, offering new insight into the spatial organization of vascular pathology. doi.org/hbpbt8
3D imaging traces vascular amyloid spread in the human brain, from surface arteries to deeper vessels
Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy (CAA).
medicalxpress.com
February 12, 2026 at 7:43 PM
3D imaging demonstrates that amyloid β deposits in cerebral amyloid angiopathy progress from surface arteries to deeper brain vessels, offering new insight into the spatial organization of vascular pathology. doi.org/hbpbt8
Pivekimab sunirine, an antibody-drug conjugate, demonstrated an 85% overall response rate as a frontline treatment for blastic plasmacytoid dendritic cell neoplasm in a recent clinical trial. doi.org/hbpbr7
Antibody-drug conjugate achieves high response rates as frontline treatment in aggressive, rare blood cancer
Seventy-five percent of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) who were treated with the antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) had a complete response, according to new data from the Phase I/II multicenter international CADENZA trial led by researchers at The University of Texas MD Anderson Cancer Center.
medicalxpress.com
February 12, 2026 at 7:40 PM
Pivekimab sunirine, an antibody-drug conjugate, demonstrated an 85% overall response rate as a frontline treatment for blastic plasmacytoid dendritic cell neoplasm in a recent clinical trial. doi.org/hbpbr7
Newly uncovered frescoes at Villa Poppaea near Pompeii display vivid original pigments and intricate motifs, offering fresh insights into Roman art and elite life before the eruption of Vesuvius.
'Virgin' frescoes emerge from Pompeii suburb
Amid the remains of a sumptuous villa near Pompeii, the hard-hatted conservationist scraped away centuries-old ash to reveal a vibrant red fresco.
phys.org
February 12, 2026 at 7:40 PM
Newly uncovered frescoes at Villa Poppaea near Pompeii display vivid original pigments and intricate motifs, offering fresh insights into Roman art and elite life before the eruption of Vesuvius.
A global analysis of over 3,100 surging glaciers shows that climate change is making these unpredictable events more hazardous, with significant risks for communities in high mountain regions. doi.org/hbpbq2
Global analysis tracks 3,100 glacier surges as climate change rewrites the rules
While most of the world's glaciers are retreating as the climate warms, a small but significant population behaves very differently—and the consequences can be severe.
phys.org
February 12, 2026 at 7:38 PM
A global analysis of over 3,100 surging glaciers shows that climate change is making these unpredictable events more hazardous, with significant risks for communities in high mountain regions. doi.org/hbpbq2
Local pollution and overfishing are limiting the effectiveness of climate refugia for coral reefs, highlighting the need to reduce local stressors to support reef survival under climate change. doi.org/hbpbpf
Mapping where local pollution and fishing suppress climate refugia for world's coral reefs
As ocean temperatures rise due to climate change, corals and other sensitive organisms survive where temperatures are less extreme.
phys.org
February 12, 2026 at 7:36 PM
Local pollution and overfishing are limiting the effectiveness of climate refugia for coral reefs, highlighting the need to reduce local stressors to support reef survival under climate change. doi.org/hbpbpf
A multi-country clinical trial confirms that high-dose primaquine and single-dose tafenoquine are safe and effective for treating P. vivax malaria in G6PD-normal patients, supporting more efficient regimens. doi.org/hbpbkj
Multi-country malaria trial shows a more efficient way to treat the disease
Landmark findings from a major malaria clinical trial led by Menzies School of Health Research (Menzies) and international collaborators have confirmed the safety and effectiveness of two Plasmodium vivax (P.
medicalxpress.com
February 12, 2026 at 7:33 PM
A multi-country clinical trial confirms that high-dose primaquine and single-dose tafenoquine are safe and effective for treating P. vivax malaria in G6PD-normal patients, supporting more efficient regimens. doi.org/hbpbkj
A new transmission model demonstrates that airborne inhalation can trigger smallpox infection within hours and estimates mpox exposure duration ranges from 8 to 127 hours, aiding outbreak response. doi.org/hbpbg2
Mpox transmission model sheds light on a medical mystery
In a groundbreaking new study, a team of researchers from South Dakota State University—led by associate professor Saikat Basu—determined the critical exposure durations for inhaled transmission of pox viruses, including smallpox and mpox, and may have provided key insights into a medical mystery.
medicalxpress.com
February 12, 2026 at 7:28 PM
A new transmission model demonstrates that airborne inhalation can trigger smallpox infection within hours and estimates mpox exposure duration ranges from 8 to 127 hours, aiding outbreak response. doi.org/hbpbg2
A new microscope enables simultaneous nanoscale measurement of temperature, magnetism, structure, and electrical properties, advancing the study and diagnostics of complex quantum materials and devices. doi.org/hbpbd9
A new microscope for the quantum age: Single nanoscale scan measures four key material properties
Physicists in Leiden have built a microscope that can measure no fewer than four key properties of a material in a single scan, all with nanoscale precision.
phys.org
February 12, 2026 at 7:25 PM
A new microscope enables simultaneous nanoscale measurement of temperature, magnetism, structure, and electrical properties, advancing the study and diagnostics of complex quantum materials and devices. doi.org/hbpbd9
New climate and machine learning models indicate that wild ancestors of wheat, barley, and rye were less widespread in the Middle East 12,000 years ago than previously thought. doi.org/hbpbb8
New study maps where wheat, barley and rye grew before the first farmers found them
Using advanced machine learning and climate models, researchers have shown that the ancestors of crops like wheat, barley, and rye probably were much less widespread in the Middle East 12,000 years ago than previously believed.
phys.org
February 12, 2026 at 7:22 PM
New climate and machine learning models indicate that wild ancestors of wheat, barley, and rye were less widespread in the Middle East 12,000 years ago than previously thought. doi.org/hbpbb8
A new equation combining AI and physics offers a more efficient way to model turbulent eddy interactions, potentially improving simulations of climate, ocean currents, and solar flows. doi.org/hbn993
A new turbulence equation for eddy interactions: AI and physics team up to tackle notoriously difficult question
The currents of the oceans, the roiling surface of the sun, and the clouds of smoke billowing off a forest fire—all are governed by the same laws of physics and give rise to a complex phenomenon known as turbulence.
phys.org
February 12, 2026 at 7:20 PM
A new equation combining AI and physics offers a more efficient way to model turbulent eddy interactions, potentially improving simulations of climate, ocean currents, and solar flows. doi.org/hbn993
A new model describes how cancer cells, immune cells, and the central nervous system interact to drive cachexia and anorexia in pancreatic cancer, highlighting GDF15 as a key factor. doi.org/hbn992
Cancer cell study sheds light on cachexia's origins
New research from the University of Oklahoma, published today in Cancer Cell, describes for the first time a "triangle regulation theory" of cancer-induced cachexia and anorexia.
medicalxpress.com
February 12, 2026 at 7:20 PM
A new model describes how cancer cells, immune cells, and the central nervous system interact to drive cachexia and anorexia in pancreatic cancer, highlighting GDF15 as a key factor. doi.org/hbn992
Predator stress significantly increases the lethal effects of road salt on freshwater snails, suggesting that combined environmental stressors may pose greater risks to aquatic ecosystems than previously recognized. doi.org/hbn99z
Predator stress makes road salt far deadlier for freshwater snails, study finds
Freshwater streams, ponds and lakes across the United States are becoming saltier, and new research from the University of Missouri shows the damage may be greater than scientists once thought.
phys.org
February 12, 2026 at 7:20 PM
Predator stress significantly increases the lethal effects of road salt on freshwater snails, suggesting that combined environmental stressors may pose greater risks to aquatic ecosystems than previously recognized. doi.org/hbn99z
Astronomers have captured the most complete observational record of a massive star collapsing directly into a black hole, offering new insights into the fate of failed supernovas.
Failed supernova provides clearest view yet of a star collapsing into a black hole
Astronomers have watched a dying star fail to explode as a supernova, instead collapsing into a black hole. The remarkable sighting is the most complete observational record ever made of a star's transformation into a black hole, allowing astronomers to construct a comprehensive physical picture of the process.
phys.org
February 12, 2026 at 7:00 PM
Astronomers have captured the most complete observational record of a massive star collapsing directly into a black hole, offering new insights into the fate of failed supernovas.
New findings show that thermospermine regulates plant vascular development by binding to methylated ribosomes, influencing the balance between woody xylem and fleshy storage tissues.
How plants balance woody xylem and fleshy tissues: Thermospermine targets methylated ribosomes
Scientists have identified a crucial mechanism that allows plants to shape their vascular systems, determining whether they grow soft edible storage organs or develop the rigid woody tissue characteristic of trees.
phys.org
February 12, 2026 at 7:00 PM
New findings show that thermospermine regulates plant vascular development by binding to methylated ribosomes, influencing the balance between woody xylem and fleshy storage tissues.
Astronomers have identified a planetary system with a rocky planet orbiting beyond gas giants, challenging established models of planet formation and suggesting new evolutionary pathways.
Unique 'inside out' planetary system reveals rocky outer world
A global team of astronomers, led by the University of Warwick, have used a European Space Agency (ESA) telescope to discover a planetary system that turns our understanding of planet formation upside down, with a distant rocky world.
phys.org
February 12, 2026 at 7:00 PM
Astronomers have identified a planetary system with a rocky planet orbiting beyond gas giants, challenging established models of planet formation and suggesting new evolutionary pathways.
Cells use mRNA fragments as molecular signals to activate backup genes, helping protect against harmful mutations and revealing a new layer of gene regulation.
mRNA fragments reveal a hidden process that protects cells from harmful mutations
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms.
phys.org
February 12, 2026 at 7:00 PM
Cells use mRNA fragments as molecular signals to activate backup genes, helping protect against harmful mutations and revealing a new layer of gene regulation.
Genomic selection is accelerating American chestnut restoration by enabling breeders to predict disease resistance and maintain ecological traits, offering a model for conserving other threatened tree species.
Genomics offers a faster path to restoring the American chestnut
For more than a century, the American chestnut, once a dominant tree across eastern North American forests, has been devastated by an invasive fungal disease that killed billions of trees in the early 1900s.
phys.org
February 12, 2026 at 7:00 PM
Genomic selection is accelerating American chestnut restoration by enabling breeders to predict disease resistance and maintain ecological traits, offering a model for conserving other threatened tree species.
Elephant trunk whiskers feature a unique stiffness gradient from base to tip, enabling precise tactile sensing and inspiring new designs for robotic touch sensors.
Elephant trunk whiskers exhibit material intelligence, revealing the secret behind an amazing sense of touch
A new study from an interdisciplinary German research collaboration, led by the Haptic Intelligence Department at the Max Planck Institute for Intelligent Systems (MPI-IS), reveals the secret to the gentle dexterity of the elephant trunk.
phys.org
February 12, 2026 at 7:00 PM
Elephant trunk whiskers feature a unique stiffness gradient from base to tip, enabling precise tactile sensing and inspiring new designs for robotic touch sensors.
The creatinine muscle index, combining creatinine and cystatin C blood tests, can help identify sarcopenia and predict mortality risk in individuals with chronic kidney disease. doi.org/hbn99s
Creatinine muscle index can identify deadly complication of chronic kidney disease
Scientists from The University of Manchester and Northern Care Alliance NHS Foundation Trust have discovered that the combination of two biomarkers can reliably identify sarcopenia, a serious condition of the muscle linked to higher mortality in chronic kidney disease (CKD).
medicalxpress.com
February 12, 2026 at 7:00 PM
The creatinine muscle index, combining creatinine and cystatin C blood tests, can help identify sarcopenia and predict mortality risk in individuals with chronic kidney disease. doi.org/hbn99s
A new AI model can estimate the optimal timing for feeding tube placement in Motor Neuron Disease patients, supporting proactive care and potentially improving quality of life. doi.org/g97ccn
AI model may predict when MND patients need feeding tubes within months
A new AI tool that accurately predicts the need for a feeding tube could transform patient care and improve quality of life for people living with Motor Neuron Disease (MND).
medicalxpress.com
February 12, 2026 at 6:40 PM
A new AI model can estimate the optimal timing for feeding tube placement in Motor Neuron Disease patients, supporting proactive care and potentially improving quality of life. doi.org/g97ccn
Analysis of Hubble images shows comet 41P/Tuttle–Giacobini–Kresak slowed, stopped, and reversed its spin direction in 2017, with rapid changes linked to outgassing and its small nucleus size. doi.org/hbn98g
Jupiter-family comet 41P/TGK slows down and reverses spin after perihelion
New analysis on 2017 Hubble images of the Jupiter-family comet, 41P/Tuttle–Giacobini–Kresak (41P/TGK), indicates that the comet underwent a spin reversal between April and December 2017.
phys.org
February 12, 2026 at 6:40 PM
Analysis of Hubble images shows comet 41P/Tuttle–Giacobini–Kresak slowed, stopped, and reversed its spin direction in 2017, with rapid changes linked to outgassing and its small nucleus size. doi.org/hbn98g
A small, low-abundance protein has been identified as essential for assembling carboxysomes, key bacterial structures that enhance carbon fixation and underpin global photosynthetic efficiency. doi.org/hbn967
A little protein with a big role in building Earth's carbon fixing machinery
An international team of scientists has discovered that a small, low-abundance protein plays a surprisingly big role in assembling carboxysomes—specialized bacterial microcompartments that enable efficient carbon fixation and underpin much of life on Earth.
phys.org
February 12, 2026 at 6:33 PM
A small, low-abundance protein has been identified as essential for assembling carboxysomes, key bacterial structures that enhance carbon fixation and underpin global photosynthetic efficiency. doi.org/hbn967
The Gulf Stream influences the climate system by transporting heat, nutrients, and carbon, supporting plankton growth and enhancing the North Atlantic’s capacity to absorb atmospheric carbon dioxide.
Exploring how the Gulf Stream affects the climate system and the carbon cycle
It is well documented that the Gulf Stream plays a pivotal role in the climate system through its transfer of heat, which ultimately supplies warmth to northern latitudes in the North Atlantic.
phys.org
February 12, 2026 at 6:25 PM
The Gulf Stream influences the climate system by transporting heat, nutrients, and carbon, supporting plankton growth and enhancing the North Atlantic’s capacity to absorb atmospheric carbon dioxide.
A new approach enables reversible DNA strand crosslinking using light or redox cues, offering dynamic control for applications in nanotechnology, drug delivery, and molecular engineering. doi.org/hbn96z
A DNA 'on-off' switch? Light and redox cues reversibly link strands for nanotech
DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases.
phys.org
February 12, 2026 at 6:20 PM
A new approach enables reversible DNA strand crosslinking using light or redox cues, offering dynamic control for applications in nanotechnology, drug delivery, and molecular engineering. doi.org/hbn96z
Non-contractile heart cells, such as fibroblasts and macrophages, create specialized regions that help sustain persistent atrial fibrillation, suggesting new targets for future therapies. doi.org/hbn96p
Non-contractile heart cells help sustain persistent atrial fibrillation, study reveals
Atrial fibrillation (AF), the most common chronic cardiac arrhythmia in clinical practice, is very challenging to treat once it becomes persistent, after which spontaneous return to normal rhythm becomes highly unlikely.
medicalxpress.com
February 12, 2026 at 5:39 PM
Non-contractile heart cells, such as fibroblasts and macrophages, create specialized regions that help sustain persistent atrial fibrillation, suggesting new targets for future therapies. doi.org/hbn96p