Huber Lab @ RU Bochum
@shuberlab.bsky.social
Research in organic and supramolecular chemistry at Ruhr-University Bochum, Germany. Key interests are applications of halogen or chalcogen bonding in solution.
Reposted by Huber Lab @ RU Bochum
Anyway, we need some joy, so here's the Egyptian foreign minister being given a Lego Pyramid by the Danish foreign minister.
November 3, 2025 at 2:35 PM
Anyway, we need some joy, so here's the Egyptian foreign minister being given a Lego Pyramid by the Danish foreign minister.
Just like halogen bonding, chalcogen bonding is not purely electrostatic - orbital interactions are also very important and my override the electrostatics. We recently published an illustrative example for this: inter-anion chalcogen bonding.
See: pubs.rsc.org/en/Content/A...
See: pubs.rsc.org/en/Content/A...
'Anti-Electrostatic' (Inter-Anion) Chalcogen Bonding Interactions
In this work, the ability of 1,2-bis(dicyanomethylene)cyclopropanide substituents to enable inter-anion interactions has been expanded to chalcogen bonding. An anionic selenium-based chalcogen-bond do...
pubs.rsc.org
October 20, 2025 at 8:03 PM
Just like halogen bonding, chalcogen bonding is not purely electrostatic - orbital interactions are also very important and my override the electrostatics. We recently published an illustrative example for this: inter-anion chalcogen bonding.
See: pubs.rsc.org/en/Content/A...
See: pubs.rsc.org/en/Content/A...
Prof. Wolfgang Kirmse, former Chair of Organic Chemistry II at Ruhr-University Bochum, has died on October 3rd. He was known, inter alia, for many fundamental contributions to carbocation chemistry and was a very well-visible representative of our chemistry department for a long time. Rest in peace.
October 15, 2025 at 8:37 AM
Prof. Wolfgang Kirmse, former Chair of Organic Chemistry II at Ruhr-University Bochum, has died on October 3rd. He was known, inter alia, for many fundamental contributions to carbocation chemistry and was a very well-visible representative of our chemistry department for a long time. Rest in peace.
Please check this announcement for an early-career group leader, hosted jointly by our cluster of excellence RESOLV and the MPI Kofo. The thematic focus should be on catalysis: jobs.ruhr-uni-bochum.de/jobposting/4...
Early Career Research (ECR) Group Leader position (m/f/d) with the thematic focus on “Catalysis” within the Cluster of Excellence RESOLV
jobs.ruhr-uni-bochum.de
October 2, 2025 at 1:54 PM
Please check this announcement for an early-career group leader, hosted jointly by our cluster of excellence RESOLV and the MPI Kofo. The thematic focus should be on catalysis: jobs.ruhr-uni-bochum.de/jobposting/4...
In a preprint, we report a particularly interesting substrate for biaxial halogen bonding with iodine(III)-based Lewis acids: allenes. We also introduce chiral variants which allow enantiodiscrimination of allenes via NMR:
September 19, 2025 at 2:52 PM
In a preprint, we report a particularly interesting substrate for biaxial halogen bonding with iodine(III)-based Lewis acids: allenes. We also introduce chiral variants which allow enantiodiscrimination of allenes via NMR:
At the end of August, we said goodbye to Julian Wolf, former PhD student and postdoc. Thanks a lot for your contributions, particularly all the work to establish highly enantioselective XB catalysis, and all the best!
September 19, 2025 at 2:22 PM
At the end of August, we said goodbye to Julian Wolf, former PhD student and postdoc. Thanks a lot for your contributions, particularly all the work to establish highly enantioselective XB catalysis, and all the best!
Reposted by Huber Lab @ RU Bochum
Wow. Check this out.
Politicians actually trying to solve problems can achieve a lot!
www.washingtonpost.com/climate-solu...
Politicians actually trying to solve problems can achieve a lot!
www.washingtonpost.com/climate-solu...
Paris said au revoir to cars. Air pollution maps reveal a dramatic change.
Air pollution fell substantially as the city restricted car traffic and made way for parks and bike lanes.
www.washingtonpost.com
August 30, 2025 at 9:15 PM
Wow. Check this out.
Politicians actually trying to solve problems can achieve a lot!
www.washingtonpost.com/climate-solu...
Politicians actually trying to solve problems can achieve a lot!
www.washingtonpost.com/climate-solu...
We welcome Katyayani and Jelke as new PhD students to our group - both will explore different aspects of halogen and chalcogen bonding organocatalysis. All the best!
August 29, 2025 at 5:30 PM
We welcome Katyayani and Jelke as new PhD students to our group - both will explore different aspects of halogen and chalcogen bonding organocatalysis. All the best!
We have now finally completed the renovation of our synthesis labs. Thanks to Ruhr-University Bochum for providing us with such excellent infrastructure!
August 29, 2025 at 5:27 PM
We have now finally completed the renovation of our synthesis labs. Thanks to Ruhr-University Bochum for providing us with such excellent infrastructure!
A paper with a Queen song title? Check! (Even though that was an easy one).
We've investigated the high pressure behavior of halogen bonding and found some unexpected solvent @solvationsci.bsky.social dependence:
pubs.acs.org/doi/10.1021/...
We've investigated the high pressure behavior of halogen bonding and found some unexpected solvent @solvationsci.bsky.social dependence:
pubs.acs.org/doi/10.1021/...
Halogen Bonding in Solution: Under Pressure
The first study of the high-pressure behavior of organic halogen bond donors in solution is presented: HP-NMR titrations were performed in various solvents, primarily with a neutral tridentate halogen...
pubs.acs.org
August 7, 2025 at 10:36 AM
A paper with a Queen song title? Check! (Even though that was an easy one).
We've investigated the high pressure behavior of halogen bonding and found some unexpected solvent @solvationsci.bsky.social dependence:
pubs.acs.org/doi/10.1021/...
We've investigated the high pressure behavior of halogen bonding and found some unexpected solvent @solvationsci.bsky.social dependence:
pubs.acs.org/doi/10.1021/...
Last monday, we bid farewell to Saber Mehrparvar now that his two-year postdoc stay came to an end. He tackled a difficult project, under high pressure, which will hopefully be published soon. Saber, it was a GREAT pleasure having you around, all the best for your future!
July 7, 2025 at 3:13 PM
Last monday, we bid farewell to Saber Mehrparvar now that his two-year postdoc stay came to an end. He tackled a difficult project, under high pressure, which will hopefully be published soon. Saber, it was a GREAT pleasure having you around, all the best for your future!
Said opus magnum (see below) is now in its final layout: highly enantioselective organocatalysis with bidentate halogen bond donors! A breakthrough that we had been hunting fir many, many years: onlinelibrary.wiley.com/doi/10.1002/...
Highly Enantioselective Organocatalysis with Bidentate Halogen Bond Donors
In a model Mukaiyama aldol reaction with unbiased substrates, high enantioselectivity was achieved with a modifiable bidentate iodine(I)-based halogen bonding organocatalyst. The crucial role of halo...
onlinelibrary.wiley.com
July 7, 2025 at 3:08 PM
Said opus magnum (see below) is now in its final layout: highly enantioselective organocatalysis with bidentate halogen bond donors! A breakthrough that we had been hunting fir many, many years: onlinelibrary.wiley.com/doi/10.1002/...
Today, Julian Wolf briliantly defended his thesis, congrats! His opus magnum can be found here: chemrxiv.org/engage/chemr.... Thanks to Raphael Stoll for chairing and to Gerald Dyker, Nils Metzler-Nolte for co-reviewing!
March 25, 2025 at 8:27 PM
Today, Julian Wolf briliantly defended his thesis, congrats! His opus magnum can be found here: chemrxiv.org/engage/chemr.... Thanks to Raphael Stoll for chairing and to Gerald Dyker, Nils Metzler-Nolte for co-reviewing!
Reposted by Huber Lab @ RU Bochum
Ein Appell von S4F an die Politik
Die Klimakrise und weitere Umweltkrisen (Biodiversitätsverlust, Überlastung biogeochemischer Stoffkreisläufe, ...) sind mittelfristig die größte Bedrohung für Sicherheit, Wirtschaft und Wohlstand, Demokratie, Zivilisation und Menschenleben.
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Die Klimakrise und weitere Umweltkrisen (Biodiversitätsverlust, Überlastung biogeochemischer Stoffkreisläufe, ...) sind mittelfristig die größte Bedrohung für Sicherheit, Wirtschaft und Wohlstand, Demokratie, Zivilisation und Menschenleben.
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March 10, 2025 at 6:21 AM
Ein Appell von S4F an die Politik
Die Klimakrise und weitere Umweltkrisen (Biodiversitätsverlust, Überlastung biogeochemischer Stoffkreisläufe, ...) sind mittelfristig die größte Bedrohung für Sicherheit, Wirtschaft und Wohlstand, Demokratie, Zivilisation und Menschenleben.
➡️
Die Klimakrise und weitere Umweltkrisen (Biodiversitätsverlust, Überlastung biogeochemischer Stoffkreisläufe, ...) sind mittelfristig die größte Bedrohung für Sicherheit, Wirtschaft und Wohlstand, Demokratie, Zivilisation und Menschenleben.
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The combined power of halogen bonding and asymmetric counteranion-directed catalysis = XB-ACDC: pubs.acs.org/doi/10.1021/.... Thanks to @mertenlab.bsky.social for structure elucidation and to the List group for this beautiful cooperation! A perfect #RESOLV project! @solvationsci.bsky.social
Asymmetric Counteranion-Directed Halogen Bonding Catalysis
Halogen bonding has been established as a promising tool in organocatalysis. Asymmetric processes are nevertheless scarce, and their applications are limited to a few studies applying chiral halogen b...
pubs.acs.org
March 3, 2025 at 7:40 PM
The combined power of halogen bonding and asymmetric counteranion-directed catalysis = XB-ACDC: pubs.acs.org/doi/10.1021/.... Thanks to @mertenlab.bsky.social for structure elucidation and to the List group for this beautiful cooperation! A perfect #RESOLV project! @solvationsci.bsky.social
So far, strong neutral halogen bond donors were often based on fluoroarenes. Here, we present ortho-carborane-based systems that clearly outcompete them: onlinelibrary.wiley.com/doi/10.1002/.... Thanks to Jas Ward and Kari Rissanen for the X-ray analyses and to Sandro Keller for assistance with ITC.
Ortho‐Carborane‐Derived Halogen Bonding Organocatalysts
Multidentate neutral halogen bonding catalysts based on iodinated icosahedral ortho-carborane moieties are introduced. Co-crystallization-studies, calorimetric measurements, and 1H NMR titrations dem...
onlinelibrary.wiley.com
February 18, 2025 at 7:29 PM
So far, strong neutral halogen bond donors were often based on fluoroarenes. Here, we present ortho-carborane-based systems that clearly outcompete them: onlinelibrary.wiley.com/doi/10.1002/.... Thanks to Jas Ward and Kari Rissanen for the X-ray analyses and to Sandro Keller for assistance with ITC.
We are hiring! Please share, thanks!
February 11, 2025 at 7:33 AM
We are hiring! Please share, thanks!
After a one-year hiatus on this platform, we have decided to move here for good - it's just a so much nicer place than the other one...
PS: For all biochemists and biologists who have started to follow us: thank you for your interest, but be aware that we don't really work much in these areas...
PS: For all biochemists and biologists who have started to follow us: thank you for your interest, but be aware that we don't really work much in these areas...
December 21, 2024 at 3:39 PM
After a one-year hiatus on this platform, we have decided to move here for good - it's just a so much nicer place than the other one...
PS: For all biochemists and biologists who have started to follow us: thank you for your interest, but be aware that we don't really work much in these areas...
PS: For all biochemists and biologists who have started to follow us: thank you for your interest, but be aware that we don't really work much in these areas...
We all wish you Merry Christmas and a great start into the New Year!
December 21, 2024 at 3:37 PM
We all wish you Merry Christmas and a great start into the New Year!
We wish you - and in particular our three followers - merry Christmas and a great start into the new year!
December 21, 2023 at 5:15 PM
We wish you - and in particular our three followers - merry Christmas and a great start into the new year!