Sofia Medvedeva
sonaida.bsky.social
Sofia Medvedeva
@sonaida.bsky.social
SHEATH
www.nature.com/articles/s41...

Thrilled to share our new study! We show that mirusviruses include lineages packed with spliceosomal introns and likely replicating in the nucleus of unicellular eukaryotes—a sharp contrast to most large and giant eukaryotic viruses that replicate in the cytoplasm.
Widespread and intron-rich mirusviruses are predicted to reproduce in nuclei of unicellular eukaryotes - Nature Microbiology
Environmental metagenomic explorations show that Mirusviricota lineages lack essential replication and transcription genes and contain spliceosomal introns, suggesting nuclear reproduction.
www.nature.com
November 28, 2025 at 1:21 PM
Reposted by Sofia Medvedeva
Very happy to share the first publication from my PhD as a preprint!!
Are you an archaea enthusiast? A network afficionado? Do you love the cell cycle?
If you answered yes to any of those questions this preprint is for you! Little 🧵 (1/11)

www.biorxiv.org/content/10.1...
Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes
The cell cycle is a series of events that occur from the moment of cell birth to cell division. In eukaryotes, cell growth, genome replication, genome segregation, and cytokinesis are strictly coordin...
www.biorxiv.org
November 26, 2024 at 11:29 AM
Have you ever heard about sheaths? Happy to share our last paper with @sgribaldo.bsky.social and Guillaume Borrel @pasteur.fr where we investigated their distribution and evolution!
doi.org/10.1093/isme...
Below a thread of our major findings:
Sheaths are diverse and abundant cell surface layers in archaea
Abstract. Prokaryotic cells employ multiple protective layers crucial for defense, structural integrity, and cellular interactions in the environment. Arch
doi.org
November 22, 2024 at 10:49 AM