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Federico Soria

@soriafn.bsky.social

97 followers 58 following 16 posts

Neurobiologist at Achucarro Basque Center for Neuroscience (GlioMatrixLab). Investigating the extracellular matrix in healthy and diseased brain 🔬🧠. Also on X (@SoriaFN)

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Federico Soria @soriafn.bsky.social · Feb 6

We are happy to present AAV-Ncan-GFP, a genetically-encoded fluorescent probe for live #imaging of the extracellular matrix in the mouse brain.

Stay tuned for the peer-reviewed version, with more insights on live #ECM monitoring by two-photon microscopy!

www.biorxiv.org/content/10.1...

Viral-mediated fluorescent labeling of hyaluronan reveals extracellular matrix dynamics in the mouse brain in vivo

The extracellular matrix (ECM) of the brain is primarily composed of the glycan polymer hyaluronan (HA), a core scaffold that nucleates proteoglycans forming a self-assembled matrix that acts as struc...

www.biorxiv.org

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Federico Soria @soriafn.bsky.social · Jun 19

Want to tag the #ECM for live imaging?

Our AAV vector, pAAV-CMVie-NcanGFP (a genetically encoded fluorescent tag for hyaluronan) is now available at Addgene!

addgene.org/235983/

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Federico Soria @soriafn.bsky.social · Jun 18

This was science fiction not long ago. Now it's a reality:
Brain-computer interface decodes language and reproduces it with nuances (tone, etc). I wonder how long until they can decode thoughts and show them as images/videos.

Black Mirror stuff!

www.nature.com/articles/d41...

World first: brain implant lets man speak with expression — and sing

Device translates thought to speech in real time.

www.nature.com

Reposted by Federico Soria

European Microglia Webinar Series @microgliaseries.bsky.social · May 27

📢 New webinar coming soon 📢
Clare Pridans from Institute for Regeneration and Repair, University of Edinburgh will be our next speaker on June 3rd. Check all the information in the flyer and add it to your calendar! 🧠👩🏻‍🔬

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Federico Soria @soriafn.bsky.social · Apr 8

Happy to be part of this beautiful work from Maria Domercq and Alejandro Montilla.
The paper explores the role of microglia in myelin clearance after demyelination, and how lipid accumulation in mice without IRF5 (immune response-related) impairs remyelination.
link.springer.com/article/10.1...

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5 - Cellular and Molecular Life Sciences

Interferon regulatory factor 5 (IRF5) is a transcription factor that plays a role in orchestrating innate immune responses, particularly in response to viral infections. Notably, IRF5 has been identif...

link.springer.com

Federico Soria @soriafn.bsky.social · Apr 2

www.nature.com/articles/s41...

Science "non-fiction"...

A streaming brain-to-voice neuroprosthesis to restore naturalistic communication - Nature Neuroscience

Naturalistic communication is an aim for neuroprostheses. Here the authors present a neuroprosthesis that restores the voice of a paralyzed person simultaneously with their speaking attempts, enabling...

www.nature.com

Federico Soria @soriafn.bsky.social · Mar 28

Super interesting symposium and great discussion at #NWG2025.

Thanks Egor and Alexander and Constanze for the invitation and the delicious lunch under the spring sun of Göttingen.

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Federico Soria @soriafn.bsky.social · Mar 27

Ready for some Extracellular Matrix science at Göttingen, within the German Neuroscience Society meeting. #NWG2025

Federico Soria @soriafn.bsky.social · Mar 25

This is next Tuesday!

European Microglia Webinar Series @microgliaseries.bsky.social · Mar 24

📢New webinar coming soon📢
Prof. Steffen Jung from Weizmann Institute of Science will be our next speaker on April 1st. Check all the information in the flyer and add it to your calendar! 🧠🔬

Federico Soria @soriafn.bsky.social · Mar 19

the paper...
www.pnas.org/doi/full/10....

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org

Federico Soria @soriafn.bsky.social · Mar 19

"What if you could listen to music without headphones and without disturbing anyone around you?"
Audible enclaves... localized pockets of sound that are isolated from their surroundings.
Los auriculares del futuro...
theconversation.com/researchers-...

Researchers created sound that can bend itself through space, reaching only your ear in a crowd

By combining ultrasound with a concept called nonlinear acoustics, you can create sound that stays silent until it reaches a specific location.

theconversation.com

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Federico Soria @soriafn.bsky.social · Mar 19

Felicitaciones!

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Reposted by Federico Soria

Federico Soria @soriafn.bsky.social · Feb 6

NcanGFP in live brain tissue

AAV-NcanGFP labeling of the extracellular matrix in live tissue

Federico Soria @soriafn.bsky.social · Feb 6

NcanGFP in live brain tissue

Federico Soria @soriafn.bsky.social · Feb 6

Viral-mediated fluorescent labeling of hyaluronan reveals extracellular matrix dynamics in the mouse brain in vivo

www.biorxiv.org

1 1 2

Federico Soria @soriafn.bsky.social · Feb 4

This is today. No recording, so it won't be available in our website.
Don't miss it!

European Microglia Webinar Series @microgliaseries.bsky.social · Jan 28

📢New webinar coming soon📢
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!

Federico Soria @soriafn.bsky.social · Jan 28

Next Tuesday!

European Microglia Webinar Series @microgliaseries.bsky.social · Jan 28

📢New webinar coming soon📢
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!

Reposted by Federico Soria

European Microglia Webinar Series @microgliaseries.bsky.social · Jan 28

📢New webinar coming soon📢
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!

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Federico Soria @soriafn.bsky.social · Jan 21

Great opportunity!

Ʌʗʜʋʗɑɼɼʘ @achucarro.bsky.social · Jan 9

We launched an open call to select a new Scientific Director for ACHUCARRO.

All the details of the call, here:
www.achucarro.org/job/scientif...

Federico Soria @soriafn.bsky.social · Jan 21

Hola Bluesky científico. Soy totalmente nuevo aquí.

Como funciona? (Hashtags, menciones, todo eso es igual?)

Cual es la principal diferencia con la red social innombrable?

Gracias 🙂