Stephen Lapinsky
@stephenlap.bsky.social
880 followers 270 following 66 posts
Critical Care Obstetric Medicine Pulmonary & Critical Care in pregnancy Sinai Health System & University of Toronto 🇨🇦🇿🇦
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stephenlap.bsky.social
Please follow @woccs.bsky.social our new Obstetric Critical Care resource and website WOCCS.org
Obstetric Critical Care |
WOCCS.org
stephenlap.bsky.social
UK population-based cohort study including 14 083 patients with hypertensive disorders of pregnancy.
HDP associated with a doubling of the risk of developing dilated cardiomyopathy. Risk was increased with severity of preeclampsia, older maternal age & postpartum hypertension.

ja.ma/3Fwf0n2
Hypertensive Disorders of Pregnancy and Long-Term Risk of Dilated Cardiomyopathy
This population cohort study uses multiple linked UK electronic health records to examine whether hypertensive disorders of pregnancy are associated with long-term risk of dilated cardiomyopathy.
ja.ma
stephenlap.bsky.social
Mechanism of preeclampsia: fascinating talk @nasom-obmed.bsky.social 2025 by Dr. Surendra Sharma on the role of impaired autophagy related to tau protein aggregation, and treatable with trehalose

pubmed.ncbi.nlm.nih.gov/38760513/
stephenlap.bsky.social
Top 5 articles in OB Medicine in 2024 presented at @nasom-obmed.bsky.social 2025 meeting
stephenlap.bsky.social
Jayson Potts opening the @nasom-obmed.bsky.social 2025 meeting in Newport, RI
stephenlap.bsky.social
New review on PlGF & sFlt1 in Obstetic care, by @sinaihealth.bsky.social leaders in the field.

journals.sagepub.com/doi/10.1177/...
Reposted by Stephen Lapinsky
nasom-obmed.bsky.social
NASOM annual conference coming up April 25-26, Newport, Rhode Island

Participate in person or virtually

Program:
nasom.org/wp-content/u...

Register at:
nasom.org/event-regist...
stephenlap.bsky.social
Smoking cessation drugs in pregnancy: large cohort study of 1st trimester exposure shows no significant increased risk of congenital malformations with nicotine replacement & varenicline. (similarly no increased risk for buproprion but limited data)

jamanetwork.com/journals/jam...
Risk of Major Congenital Malformations Following Prenatal Exposure to Smoking Cessation Medicines
This cohort study examines whether prenatal use of smoking cessation pharmacotherapies is associated with increased risks of major congenital malformations.
jamanetwork.com
Reposted by Stephen Lapinsky
greenjrnl.bsky.social
New research examining subcapsular liver hematomas in preeclampsia and HELLP syndrome: ow.ly/M7vR50Vj7OR
stephenlap.bsky.social
Excellent podcast by Catherine Nelson-Piercy and Marie Teil discussing the challenges women with chronic medical diseases face in pregnancy, the lack of data to inform decisions, and the move towards including pregnant women in research studies

scanmail.trustwave.com?c=8248&d=jaz...
scanmail.trustwave.com
stephenlap.bsky.social
Time to register for NASOM 2025
April 25-26, Newport, Rhode Island

Or participate virtually!

Early bird rate ends March 31st

nasom.org/current-year...
Reposted by Stephen Lapinsky
jamiedaw.bsky.social
I received one of the 232 NIH grant "terminations" sent to scientists at Columbia last night. My research focuses on improving maternal and child health in the US. Also affected: ongoing clinical trials, research training programs, and research centers that aim to improve the health of Americans.
Hundreds of research grants at Columbia canceled following Trump edict, administrator says
The National Institutes of Health is terminating 232 grants for scientific research at Columbia University Irving Medical Center, according to an email an administrator sent to faculty.
gothamist.com
stephenlap.bsky.social
Obstetrics & Gynecology, the Green Journal, has left Twitter and is now here!

@greenjrnl.bsky.social
Reposted by Stephen Lapinsky
nasom-obmed.bsky.social
Letter from NASOM President, Jayson Potts, regarding the upcoming NASOM conference.
- now a virtual option
- added session on impact of political changes on women's health

𝙉𝙚𝙬𝙥𝙤𝙧𝙩, 𝙍𝙝𝙤𝙙𝙚 𝙄𝙨𝙡𝙖𝙣𝙙 𝙤𝙣 𝘼𝙥𝙧𝙞𝙡 25 & 26, 2025

Details & registration at:

nasom.org/current-year...
Reposted by Stephen Lapinsky
cardioob.bsky.social
Pregnancies in women after peri-partum cardiomyopathy #PPCM: global ESC EuroObservational Registry

#CardioSky #CardioObstetrics
academic.oup.com/eurheartj/ad...
@escardio.bsky.social @jgrapsa.bsky.social @anastasiasmihaili.bsky.social @garimasharmamd.bsky.social @emilyswlau.bsky.social
stephenlap.bsky.social
Cystic fibrosis & pregnancy

New data from American Cystic Fibrosis Foundation Patient Registry.

Pregnancy assoc with:
- reduced hazard of death compared to never-pregnant
- no significant impact on lung function.

www.sciencedirect.com/science/arti...
stephenlap.bsky.social
I never really thought much about where our fruit came from, but now that we buy non-American, these Italian & Israeli options are great! 🇨🇦
Reposted by Stephen Lapinsky
bethangoulden.bsky.social
Another report of pregnancy associated HLH in @OBMedicine, with no driver identified. Important to also highlight the role of anakinra & the 3Fs (fever, falling counts & ⬆️ ferritin) as a quick screen. In the UK, also remember the HLH MDT & @NPEU_UKOSS study.

journals.sagepub.com/doi/10.1177/...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
stephenlap.bsky.social
I like this, will try! I usually give a 1-2 hr trial of vasopressin. There are definitely vasopressin responders and non-responders - I view it as replacing a hormone deficiency rather than acting purely as pressor.
trial.here
stephenlap.bsky.social
Well Alberta, we (in Toronto) accepted your overflow critically ill COVID patients in 2021. Remember, if they come here they receive evidence-based medicine, no ivermectin included!